erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Hypersplenism D006971 3 associated lipids
Splenic Infarction D013159 1 associated lipids
Mastoiditis D008417 2 associated lipids
Onychomycosis D014009 2 associated lipids
Hematemesis D006396 1 associated lipids
Pityriasis Rosea D017515 3 associated lipids
Duodenogastric Reflux D004383 2 associated lipids
Trisomy D014314 6 associated lipids
Epidural Abscess D020802 1 associated lipids
Trench Fever D014205 1 associated lipids
Herpes Genitalis D006558 2 associated lipids
Compartment Syndromes D003161 1 associated lipids
Wounds, Gunshot D014948 2 associated lipids
Pericoronitis D010497 2 associated lipids
Postoperative Nausea and Vomiting D020250 1 associated lipids
Eye Infections, Parasitic D015822 2 associated lipids
Myiasis D009198 1 associated lipids
Digestive System Abnormalities D004065 1 associated lipids
Choroiditis D002833 1 associated lipids
Pelvic Infection D034161 1 associated lipids
Seroma D049291 2 associated lipids
Choanal Atresia D002754 1 associated lipids
Limb Deformities, Congenital D017880 4 associated lipids
Microphthalmos D008850 1 associated lipids
Chalazion D017043 1 associated lipids
Acalculous Cholecystitis D042101 3 associated lipids
Pneumonia, Ventilator-Associated D053717 1 associated lipids
Tooth Fractures D014082 2 associated lipids
Sebaceous Gland Diseases D012625 1 associated lipids
Adrenocortical Carcinoma D018268 4 associated lipids
Granuloma, Respiratory Tract D015769 1 associated lipids
Staphylococcal Scalded Skin Syndrome D013206 1 associated lipids
Stomatognathic Diseases D009057 1 associated lipids
Moraxellaceae Infections D045828 3 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
Fecal Incontinence D005242 1 associated lipids
Atrioventricular Block D054537 1 associated lipids
Abdominal Abscess D018784 2 associated lipids
Vagus Nerve Injuries D061223 1 associated lipids
Pyloric Stenosis, Hypertrophic D046248 2 associated lipids
Hoarseness D006685 2 associated lipids
Occupational Injuries D060051 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
De Francesco MA et al. Phenotypes, genotypes, serotypes and molecular epidemiology of erythromycin-resistant Streptococcus agalactiae in Italy. 2012 Eur. J. Clin. Microbiol. Infect. Dis. pmid:22120421
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Popowska M et al. Influence of soil use on prevalence of tetracycline, streptomycin, and erythromycin resistance and associated resistance genes. 2012 Antimicrob. Agents Chemother. pmid:22203596
Biester EM et al. Identification of avian wax synthases. 2012 BMC Biochem. pmid:22305293
Jaglic Z et al. Distribution, characterization and genetic bases of erythromycin resistance in staphylococci and enterococci originating from livestock. 2012 Zoonoses Public Health pmid:21843202
Shiu WK et al. Antibacterial acylphloroglucinols from Hypericum olympicum. 2012 J. Nat. Prod. pmid:21899267
Carbonero A et al. Campylobacter spp., C. jejuni and C. upsaliensis infection-associated factors in healthy and ill dogs from clinics in Cordoba, Spain. Screening tests for antimicrobial susceptibility. 2012 Comp. Immunol. Microbiol. Infect. Dis. pmid:22640550
Sadeghi SJ et al. Drug-drug interactions and cooperative effects detected in electrochemically driven human cytochrome P450 3A4. 2012 Bioelectrochemistry pmid:22480862
Nunoi H et al. A relationship between motilin and growth hormone secretagogue receptors. 2012 Regul. Pept. pmid:22465164
Bosnar M et al. N'-substituted-2'-O,3'-N-carbonimidoyl bridged macrolides: novel anti-inflammatory macrolides without antimicrobial activity. 2012 J. Med. Chem. pmid:22697905
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Maeda Y et al. UV-C-irradiation sublethal stress does not alter antibiotic susceptibility of the viridans group streptococci to β-lactam, macrolide, and fluoroquinolone antibiotic agents. 2012 J Investig Clin Dent pmid:22887906
Aiello A et al. Aplisulfamines, new sulfoxide-containing metabolites from an aplidium tunicate: absolute stereochemistry at chiral sulfur and carbon atoms assigned through an original combination of spectroscopic and computational methods. 2012 Mar Drugs pmid:22363220
Molnari JC and Myers AL Carbonyl reduction of bupropion in human liver. 2012 Xenobiotica pmid:22339467
Noto MJ and Wheeler AP Macrolides for acute lung injury. 2012 Chest pmid:22553255
Guan Y et al. [Preliminary study of effects of andrographolide on Staphylococcus epidermidis biofilms]. 2012 Zhongguo Zhong Yao Za Zhi pmid:23126203
Kelley C et al. 3-Phenyl substituted 6,7-dimethoxyisoquinoline derivatives as FtsZ-targeting antibacterial agents. 2012 Bioorg. Med. Chem. pmid:23127490
Blystad H et al. Increased incidence of Mycoplasma pneumoniae infection in Norway 2011. 2012 Euro Surveill. pmid:22321136
Laine L and Jensen DM Management of patients with ulcer bleeding. 2012 Am. J. Gastroenterol. pmid:22310222
Waseem S et al. Spectrum of gastroparesis in children. 2012 J. Pediatr. Gastroenterol. Nutr. pmid:22314391
Henningsen E and Bygum A Budesonide-induced periorificial dermatitis presenting as chalazion and blepharitis. 2011 Sep-Oct Pediatr Dermatol pmid:21895758
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Fessler AT et al. Novel apramycin resistance gene apmA in bovine and porcine methicillin-resistant Staphylococcus aureus ST398 isolates. 2011 Antimicrob. Agents Chemother. pmid:20876371
Ogungbenro K et al. A semi-mechanistic gastric emptying model for the population pharmacokinetic analysis of orally administered acetaminophen in critically ill patients. 2011 Pharm. Res. pmid:20949310
Ridley EJ and Davies AR Practicalities of nutrition support in the intensive care unit: the usefulness of gastric residual volume and prokinetic agents with enteral nutrition. 2011 Nutrition pmid:21295944
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Watanabe I et al. Combined effect of disopyramide and erythromycin on ventricular repolarization in dogs with complete atrioventricular block. 2011 Int Heart J pmid:22188715
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Ma S et al. Synthesis and antibacterial evaluation of novel clarithromycin derivatives with C-4″ elongated arylalkyl groups against macrolide-resistant strains. 2011 Eur J Med Chem pmid:21159410
Mak PJ et al. Defining CYP3A4 structural responses to substrate binding. Raman spectroscopic studies of a nanodisc-incorporated mammalian cytochrome P450. 2011 J. Am. Chem. Soc. pmid:21207936
Ren GW et al. Rapid detection of point mutations in domain V of the 23S rRNA gene in erythromycin-resistant Campylobacter isolates by pyrosequencing. 2011 Foodborne Pathog. Dis. pmid:21166562
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Khan NW et al. Antimicrobial activity of erythromycin and clarithromycin against clinical isolates of Escherichia coli, Staphylococcus aureus, Klebsiella and Proteus by disc diffusion method. 2011 Pak J Pharm Sci pmid:21190914
Lee HY et al. Improved precursor-directed biosynthesis in E. coli via directed evolution. 2011 J. Antibiot. pmid:21081955
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Jessick AM et al. Optimization of analytical methods to improve detection of erythromycin from water and sediment. 2011 J Environ Sci Health B pmid:21877980
Lee CY et al. Identification and treatment of bisphosphonate-associated actinomycotic osteonecrosis of the jaws. 2011 Implant Dent pmid:21881516
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Maezono H et al. Antibiofilm effects of azithromycin and erythromycin on Porphyromonas gingivalis. 2011 Antimicrob. Agents Chemother. pmid:21911560
Lehtopolku M et al. Ribosomal mutations as the main cause of macrolide resistance in Campylobacter jejuni and Campylobacter coli. 2011 Antimicrob. Agents Chemother. pmid:21911571
Drago L et al. Macrolide resistance and in vitro selection of resistance to antibiotics in Lactobacillus isolates. 2011 J. Microbiol. pmid:21887650
Liu K et al. Direct entry to erythronolides via a cyclic bis[allene]. 2011 J. Am. Chem. Soc. pmid:21894913
Torra S et al. Meal size can be decreased in obese subjects through pharmacological acceleration of gastric emptying (The OBERYTH trial). 2011 Int J Obes (Lond) pmid:20938444
Li MJ et al. High electrochemiluminescence of a new water-soluble iridium(III) complex for determination of antibiotics. 2011 Analyst pmid:20944848
Haenni M et al. ermB-mediated erythromycin resistance in Streptococcus uberis from bovine mastitis. 2011 Vet. J. pmid:20667752
Chen I et al. Emergence of erythromycin- and clindamycin-resistant Streptococcus pyogenes emm 90 strains in Hawaii. 2011 J. Clin. Microbiol. pmid:21068284
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Bilk S et al. Antimicrobial susceptibilities and occurrence of resistance genes in bovine Helcococcus ovis isolates. 2011 Vet. Microbiol. pmid:21131144
Zou X et al. An assessment of seed quality on erythromycin production by recombinant Saccharopolyspora erythraea strain. 2011 Bioresour. Technol. pmid:21134745
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Bosnjakovic A et al. Poly(amidoamine) dendrimer-erythromycin conjugates for drug delivery to macrophages involved in periprosthetic inflammation. 2011 Nanomedicine pmid:21059404
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Amarir-Bouhram J et al. Low efficiency of homology-facilitated illegitimate recombination during conjugation in Escherichia coli. 2011 PLoS ONE pmid:22194937
Ng PC Erythromycin as a prokinetic agent in newborns--useful or doubtful. Commentary on Y. Mansi et al.: Randomized controlled trial of a high dose of oral erythromycin for the treatment of feeding intolerance in preterm infants (Neonatology 2011;100:290-294). 2011 Neonatology pmid:21701224
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Serisier DJ and Martin ML Long-term, low-dose erythromycin in bronchiectasis subjects with frequent infective exacerbations. 2011 Respir Med pmid:21367595
Almofti YA et al. Impact of erythromycin resistance on the virulence properties and fitness of Campylobacter jejuni. 2011 Microb. Pathog. pmid:21377522
Luo DQ et al. In vitro activities of erythromycin, tetracycline and levofloxacin alone and in dual combinations against ureaplasma spp. 2011 Chemotherapy pmid:21430380
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Del Grosso M et al. Genetic resistance elements carrying mef subclasses other than mef(A) in Streptococcus pyogenes. 2011 Antimicrob. Agents Chemother. pmid:21502613
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Ozkok IP et al. Respirometric assessment of substrate binding by antibiotics in peptone biodegradation. 2011 J Environ Sci Health A Tox Hazard Subst Environ Eng pmid:22029701
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Zhao DL et al. Characterization of a cryptic plasmid pSM429 and its application for heterologous expression in psychrophilic Pseudoalteromonas. 2011 Microb. Cell Fact. pmid:21542941
Gannon M et al. Clinical inquiries. Which oral antibiotics are best for acne? 2011 J Fam Pract pmid:21544278
Chia HY et al. Follicular spicules associated with Propionibacterium acnes in response to erythromycin. 2011 J. Dermatol. pmid:21544949
Nguyen TT et al. A food-grade system for inducible gene expression in Lactobacillus plantarum using an alanine racemase-encoding selection marker. 2011 J. Agric. Food Chem. pmid:21504147
Tilmant K et al. Comparison of a genomic and a multiplex cell imaging approach for the detection of phospholipidosis. 2011 Toxicol In Vitro pmid:21515356
Ma X and Ma S Significant breakthroughs in search for anti-infectious agents derived from erythromycin A. 2011 Curr. Med. Chem. pmid:21517774
Boecxstaens V et al. Modulation of the postprandial acid and bile pockets at the gastro-oesophageal junction by drugs that affect gastric motility. 2011 Aliment. Pharmacol. Ther. pmid:21517922
Sugawara A et al. Novel 12-membered non-antibiotic macrolides from erythromycin A; EM900 series as novel leads for anti-inflammatory and/or immunomodulatory agents. 2011 Bioorg. Med. Chem. Lett. pmid:21524580
Chen HX et al. [Compound erythromycin sustained release preparation and its in vitro release]. 2011 Yao Xue Xue Bao pmid:22260035
Wei Z et al. [Treatment of low-dose erythromycin and sinus displacement on sinusitis in patients with nasopharyngeal carcinoma after radiotherapy]. 2011 Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi pmid:22260078
Bansal BK et al. Elimination of erythromycin in milk after intramammary administration in cows with specific mastitis: relation to dose, milking frequency and udder health. 2011 Trop Anim Health Prod pmid:20844949