erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Hypersplenism D006971 3 associated lipids
Splenic Infarction D013159 1 associated lipids
Mastoiditis D008417 2 associated lipids
Onychomycosis D014009 2 associated lipids
Hematemesis D006396 1 associated lipids
Pityriasis Rosea D017515 3 associated lipids
Duodenogastric Reflux D004383 2 associated lipids
Trisomy D014314 6 associated lipids
Epidural Abscess D020802 1 associated lipids
Trench Fever D014205 1 associated lipids
Herpes Genitalis D006558 2 associated lipids
Compartment Syndromes D003161 1 associated lipids
Wounds, Gunshot D014948 2 associated lipids
Pericoronitis D010497 2 associated lipids
Postoperative Nausea and Vomiting D020250 1 associated lipids
Eye Infections, Parasitic D015822 2 associated lipids
Myiasis D009198 1 associated lipids
Digestive System Abnormalities D004065 1 associated lipids
Choroiditis D002833 1 associated lipids
Pelvic Infection D034161 1 associated lipids
Seroma D049291 2 associated lipids
Choanal Atresia D002754 1 associated lipids
Limb Deformities, Congenital D017880 4 associated lipids
Microphthalmos D008850 1 associated lipids
Chalazion D017043 1 associated lipids
Acalculous Cholecystitis D042101 3 associated lipids
Pneumonia, Ventilator-Associated D053717 1 associated lipids
Tooth Fractures D014082 2 associated lipids
Sebaceous Gland Diseases D012625 1 associated lipids
Adrenocortical Carcinoma D018268 4 associated lipids
Granuloma, Respiratory Tract D015769 1 associated lipids
Staphylococcal Scalded Skin Syndrome D013206 1 associated lipids
Stomatognathic Diseases D009057 1 associated lipids
Moraxellaceae Infections D045828 3 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
Fecal Incontinence D005242 1 associated lipids
Atrioventricular Block D054537 1 associated lipids
Abdominal Abscess D018784 2 associated lipids
Vagus Nerve Injuries D061223 1 associated lipids
Pyloric Stenosis, Hypertrophic D046248 2 associated lipids
Hoarseness D006685 2 associated lipids
Occupational Injuries D060051 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Xu J et al. [Prognosticating the region-selectivity in the O-methylation reaction of erythromycins by conformational search model]. 2003 Yao Xue Xue Bao pmid:12778744
Liu L et al. [Synthesis of derivatives of (9S)-12-methylene erythromycin and their antibacterial activity in vitro]. 2005 Yao Xue Xue Bao pmid:16220785
Watanabe Y et al. [Relationship between quality and serum level after the oral administration of commercial erythromycin tablets in man (author's transl)]. 1977 Yakugaku Zasshi pmid:911413
Matsuoka M [Study of macrolide, lincosamide, and streptogramin B antibiotics resistance in Staphylococcus aureus]. 2000 Yakugaku Zasshi pmid:10774259
Nakamura H et al. Effect of particle size on mixing degree in dispensation. 2004 Yakugaku Zasshi pmid:15049131
Nakamura H et al. Effect of mixing method on the mixing degree during the preparation of triturations. 2004 Yakugaku Zasshi pmid:15049130
Watanabe Y et al. [Effect of dissolving pH of enteric coating agent on bioavailability of enteric coated tablets of erythromycin in man (author's transl)]. 1978 Yakugaku Zasshi pmid:30834
Miyazaki M et al. [Trends and antimicrobial susceptibilities of clinical methicillin-resistant Staphylococcus aureus isolates in Fukuoka University Chikushi Hospital 2008-2012]. 2014 Yakugaku Zasshi pmid:24492229
Otsuka M et al. [Studies on fungicides. XIV. Effect of erythromycin on the growth of fungal mycelia (author's transl)]. 1978 Yakugaku Zasshi pmid:566318
Zhang Y et al. [Erythromycin restores oxidative stress-induced corticosteroid responsiveness of human THP-1 cells by up-regulating the expression of histone deacetylase 2]. 2014 Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi pmid:24721407
Ung D et al. Metabolic interactions between prokinetic agents domperidone and erythromycin: an in vitro analysis. 2009 Xenobiotica pmid:19575604
Hu J et al. Possible multiple transporters were involved in hepatobiliary excretion of antofloxacin in rats. 2007 Xenobiotica pmid:17614005
Salimi A et al. Toxicity of macrolide antibiotics on isolated heart mitochondria: a justification for their cardiotoxic adverse effect. 2016 Xenobiotica pmid:26068526
Emoto C et al. Cooperativity of alpha-naphthoflavone in cytochrome P450 3A-dependent drug oxidation activities in hepatic and intestinal microsomes from mouse and human. 2001 Xenobiotica pmid:11491388
Bickel MH et al. Entero-bacterial formation of cyclohexylamine in rats ingesting cyclamate. 1974 Xenobiotica pmid:4372812
Yamazaki H et al. Effects of roxithromycin, erythromycin and troleandomycin on their N-demethylation by rat and human cytochrome P450 enzymes. 1996 Xenobiotica pmid:8948090
Pasic J et al. The interaction between chronic oral slow-release theophylline and single-dose intravenous erythromycin. 1987 Xenobiotica pmid:3604256
Yamazaki H and Shimada T Formation in vitro of an inhibitory cytochrome P450 x Fe2+-metabolite complex with roxithromycin and its decladinosyl, O-dealkyl and N-demethyl metabolites in rat liver microsomes. 1998 Xenobiotica pmid:9849646
Ward KW et al. Exploration of the African green monkey as a preclinical pharmacokinetic model: oral pharmacokinetic parameters and drug-drug interactions. 2009 Xenobiotica pmid:19280525
Kaye B and Roberts DW The metabolism of oxamniquine in the gut wall. 1980 Xenobiotica pmid:7395269