erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Juntunen P et al. | Campylobacter coli isolates from Finnish farrowing farms using aminopenicillins: high prevalence of bla(OXA-61) and β-lactamase production, but low MIC values. | 2012 | Foodborne Pathog. Dis. | pmid:22924522 |
Kwiatkowska B and Maślińska M | Macrolide therapy in chronic inflammatory diseases. | 2012 | Mediators Inflamm. | pmid:22969171 |
Mulholland S et al. | Antibiotics for community-acquired lower respiratory tract infections secondary to Mycoplasma pneumoniae in children. | 2012 | Cochrane Database Syst Rev | pmid:22972079 |
Rashed SM et al. | Genetic characteristics of drug-resistant Vibrio cholerae O1 causing endemic cholera in Dhaka, 2006-2011. | 2012 | J. Med. Microbiol. | pmid:22977073 |
Mokhber-Dezfooli MR et al. | Effect of abomasal emptying rate on the apparent efficiency of colostral immunoglobulin G absorption in neonatal Holstein-Friesian calves. | 2012 | J. Dairy Sci. | pmid:22981576 |
Wang L et al. | Persistence of resistance to erythromycin and tetracycline in swine manure during simulated composting and lagoon treatments. | 2012 | Microb. Ecol. | pmid:21811793 |
Oo C and Shah B | Does erythromycin have anti-inflammatory effects independent of its antimicrobial action? | 2012 | J Clin Pharmacol | pmid:21868717 |
Janssen BD et al. | Analysis of aminoacyl- and peptidyl-tRNAs by gel electrophoresis. | 2012 | Methods Mol. Biol. | pmid:22736012 |
LeTourneau N et al. | Synthesis and antibacterial activity of desosamine-modified macrolide derivatives. | 2012 | Bioorg. Med. Chem. Lett. | pmid:22738632 |
Harvey CJ et al. | Precursor directed biosynthesis of an orthogonally functional erythromycin analogue: selectivity in the ribosome macrolide binding pocket. | 2012 | J. Am. Chem. Soc. | pmid:22741553 |
KurinÄiÄ M et al. | Effects of efflux pump inhibitors on erythromycin, ciprofloxacin, and tetracycline resistance in Campylobacter spp. isolates. | 2012 | Microb. Drug Resist. | pmid:22741576 |
Tran TD et al. | Synthesis and anti Methicillin resistant Staphylococcus aureus activity of substituted chalcones alone and in combination with non-beta-lactam antibiotics. | 2012 | Bioorg. Med. Chem. Lett. | pmid:22727643 |
Sommerfeld Ross S and Fiegel J | Nutrient dispersion enhances conventional antibiotic activity against Pseudomonas aeruginosa biofilms. | 2012 | Int. J. Antimicrob. Agents | pmid:22727773 |
Shi JG et al. | The effect of CYP3A4 inhibition or induction on the pharmacokinetics and pharmacodynamics of orally administered ruxolitinib (INCB018424 phosphate) in healthy volunteers. | 2012 | J Clin Pharmacol | pmid:21602517 |
Gokmen T et al. | A controlled trial of erythromycin and UDCA in premature infants during parenteral nutrition in minimizing feeding intolerance and liver function abnormalities. | 2012 | J Perinatol | pmid:21566568 |
GarcÃa-Pérez ME et al. | Picea mariana bark: a new source of trans-resveratrol and other bioactive polyphenols. | 2012 | Food Chem | pmid:22953840 |
Imai Y et al. | Development of the ability to produce secondary metabolites in Streptomyces through the acquisition of erythromycin resistance. | 2012 | J. Antibiot. | pmid:22491137 |
Hellmann-Regen J et al. | Retinoic acid as target for local pharmacokinetic interaction with modafinil in neural cells. | 2012 | Eur Arch Psychiatry Clin Neurosci | pmid:22434147 |
Vendrell D et al. | Accumulation and depletion kinetics of erythromycin in rainbow trout (Oncorhynchus mykiss). | 2012 | Prev. Vet. Med. | pmid:22436556 |
Martins ER et al. | Dominance of serotype Ia among group B Streptococci causing invasive infections in nonpregnant adults in Portugal. | 2012 | J. Clin. Microbiol. | pmid:22219307 |
Golparian D et al. | In vitro activity of the new fluoroketolide solithromycin (CEM-101) against a large collection of clinical Neisseria gonorrhoeae isolates and international reference strains, including those with high-level antimicrobial resistance: potential treatment option for gonorrhea? | 2012 | Antimicrob. Agents Chemother. | pmid:22354296 |
Devlin MJ et al. | Gastric emptying and symptoms of bulimia nervosa: effect of a prokinetic agent. | 2012 | Physiol. Behav. | pmid:22361261 |
Chini P et al. | Effect of azithromycin on small bowel motility in patients with gastrointestinal dysmotility. | 2012 | Scand. J. Gastroenterol. | pmid:22364597 |
Gazzola S et al. | Assessment of tetracycline and erythromycin resistance transfer during sausage fermentation by culture-dependent and -independent methods. | 2012 | Food Microbiol. | pmid:22365347 |
Palumbo Piccionello A et al. | Synthesis and preliminary antibacterial evaluation of Linezolid-like 1,2,4-oxadiazole derivatives. | 2012 | Eur J Med Chem | pmid:22365410 |
Pešić D et al. | Design, synthesis, and in vitro activity of novel 2'-O-substituted 15-membered azalides. | 2012 | J. Med. Chem. | pmid:22380766 |
Shore EM and Yudin MH | Choice of antibiotic for group B streptococcus in women in labour based on antibiotic sensitivity testing. | 2012 | J Obstet Gynaecol Can | pmid:22385665 |
Pinto A et al. | 6-Deoxyerythronolide B synthase thioesterase-catalyzed macrocyclization is highly stereoselective. | 2012 | Org. Lett. | pmid:22519860 |
Yuzawa S et al. | Role of a conserved arginine residue in linkers between the ketosynthase and acyltransferase domains of multimodular polyketide synthases. | 2012 | Biochemistry | pmid:22509729 |
Wang Y et al. | The preferred conformation of erythro- and threo-1,2-difluorocyclododecanes. | 2012 | Beilstein J Org Chem | pmid:23019458 |
Michael M et al. | Docetaxel pharmacokinetics and its correlation with two in vivo probes for cytochrome P450 enzymes: the C(14)-erythromycin breath test and the antipyrine clearance test. | 2012 | Cancer Chemother. Pharmacol. | pmid:21626050 |
Shimizu S et al. | Reactivity of lignin with different composition of aromatic syringyl/guaiacyl structures and erythro/threo side chain structures in β-O-4 type during alkaline delignification: as a basis for the different degradability of hardwood and softwood lignin. | 2012 | J. Agric. Food Chem. | pmid:22694300 |
Chen C et al. | Isolation and characterization of LS1924A, a new analog of emycins. | 2012 | J. Antibiot. | pmid:22569162 |
Mandisodza O et al. | Arcobacter species in diarrhoeal faeces from humans in New Zealand. | 2012 | N. Z. Med. J. | pmid:22522270 |
Gao J et al. | Antibiotic resistance of Streptococcus agalactiae from cows with mastitis. | 2012 | Vet. J. | pmid:22627045 |
Zhou Y et al. | Erythromycin ameliorates cigarette-smoke-induced emphysema and inflammation in rats. | 2012 | Transl Res | pmid:22633097 |
Yu DJ et al. | Cornmeal-induced resistance to ciprofloxacin and erythromycin in enterococci. | 2012 | Chemosphere | pmid:22633859 |
Karlgren M et al. | Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. | 2012 | J. Med. Chem. | pmid:22541068 |
Noormohamed A and Fakhr MK | Incidence and antimicrobial resistance profiling of Campylobacter in retail chicken livers and gizzards. | 2012 | Foodborne Pathog. Dis. | pmid:22545960 |
Leung HW et al. | Distribution, fate and risk assessment of antibiotics in sewage treatment plants in Hong Kong, South China. | 2012 | Environ Int | pmid:21450345 |
Pinto TF et al. | Tolerance to enteral nutrition therapy in traumatic brain injury patients. | 2012 | Brain Inj | pmid:22571511 |
Giovanetti E et al. | ICESp2905, the erm(TR)-tet(O) element of Streptococcus pyogenes, is formed by two independent integrative and conjugative elements. | 2012 | Antimicrob. Agents Chemother. | pmid:21986826 |
Izumikawa M et al. | JBIR-78 and JBIR-95: phenylacetylated peptides isolated from Kibdelosporangium sp. AK-AA56. | 2012 | J. Nat. Prod. | pmid:22264203 |
Li M et al. | Effect of erythromycin on cigarette-induced histone deacetylase protein expression and nuclear factor-κB activity in human macrophages in vitro. | 2012 | Int. Immunopharmacol. | pmid:22265969 |
PiÄ…tkowska E et al. | The strongest resistance of Staphylococcus aureus to erythromycin is caused by decreasing uptake of the antibiotic into the cells. | 2012 | Cell. Mol. Biol. Lett. | pmid:23001512 |
Leiding JW et al. | Successful sirolimus graded dose challenge in an erythromycin-allergic patient. | 2012 | Ann. Allergy Asthma Immunol. | pmid:23010239 |
Brill S et al. | Transforming a drug/H+ antiporter into a polyamine importer by a single mutation. | 2012 | Proc. Natl. Acad. Sci. U.S.A. | pmid:23035252 |
Kou X et al. | Synthesis, characterization and adsorption behavior of molecularly imprinted nanospheres for erythromycin using precipitation polymerization. | 2012 | J Nanosci Nanotechnol | pmid:23035481 |
Ashour S and Bayram R | Novel spectrophotometric method for determination of some macrolide antibiotics in pharmaceutical formulations using 1,2-naphthoquinone-4-sulphonate. | 2012 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:23041925 |