erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Hypersplenism D006971 3 associated lipids
Splenic Infarction D013159 1 associated lipids
Mastoiditis D008417 2 associated lipids
Onychomycosis D014009 2 associated lipids
Hematemesis D006396 1 associated lipids
Pityriasis Rosea D017515 3 associated lipids
Duodenogastric Reflux D004383 2 associated lipids
Trisomy D014314 6 associated lipids
Epidural Abscess D020802 1 associated lipids
Trench Fever D014205 1 associated lipids
Herpes Genitalis D006558 2 associated lipids
Compartment Syndromes D003161 1 associated lipids
Wounds, Gunshot D014948 2 associated lipids
Pericoronitis D010497 2 associated lipids
Postoperative Nausea and Vomiting D020250 1 associated lipids
Eye Infections, Parasitic D015822 2 associated lipids
Myiasis D009198 1 associated lipids
Digestive System Abnormalities D004065 1 associated lipids
Choroiditis D002833 1 associated lipids
Pelvic Infection D034161 1 associated lipids
Seroma D049291 2 associated lipids
Choanal Atresia D002754 1 associated lipids
Limb Deformities, Congenital D017880 4 associated lipids
Microphthalmos D008850 1 associated lipids
Chalazion D017043 1 associated lipids
Acalculous Cholecystitis D042101 3 associated lipids
Pneumonia, Ventilator-Associated D053717 1 associated lipids
Tooth Fractures D014082 2 associated lipids
Sebaceous Gland Diseases D012625 1 associated lipids
Adrenocortical Carcinoma D018268 4 associated lipids
Granuloma, Respiratory Tract D015769 1 associated lipids
Staphylococcal Scalded Skin Syndrome D013206 1 associated lipids
Stomatognathic Diseases D009057 1 associated lipids
Moraxellaceae Infections D045828 3 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
Fecal Incontinence D005242 1 associated lipids
Atrioventricular Block D054537 1 associated lipids
Abdominal Abscess D018784 2 associated lipids
Vagus Nerve Injuries D061223 1 associated lipids
Pyloric Stenosis, Hypertrophic D046248 2 associated lipids
Hoarseness D006685 2 associated lipids
Occupational Injuries D060051 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Ramos CJ and Antonetti DA The role of small GTPases and EPAC-Rap signaling in the regulation of the blood-brain and blood-retinal barriers. 2017 Tissue Barriers pmid:28632993
Sader HS et al. Antimicrobial Susceptibility Trends among Staphylococcus aureus Isolates from U.S. Hospitals: Results from 7 Years of the Ceftaroline (AWARE) Surveillance Program, 2010 to 2016. 2017 Antimicrob. Agents Chemother. pmid:28630196
Post A et al. Antibiotic susceptibility profiles among Campylobacter isolates obtained from international travelers between 2007 and 2014. 2017 Eur. J. Clin. Microbiol. Infect. Dis. pmid:28623550
Ishikawa Y et al. Inactivation kinetics and residual activity of CYP3A4 after treatment with erythromycin. 2017 Biopharm Drug Dispos pmid:28425104
Rea E and Husbands E Erythromycin: prophylaxis against recurrent small bowel obstruction. 2017 BMJ Support Palliat Care pmid:28356304
Hawkins PA et al. Cross-resistance to lincosamides, streptogramins A and pleuromutilins in Streptococcus agalactiae isolates from the USA. 2017 J. Antimicrob. Chemother. pmid:28333320
Adhikari RP et al. Inducible clindamycin and methicillin resistant Staphylococcus aureus in a tertiary care hospital, Kathmandu, Nepal. 2017 BMC Infect. Dis. pmid:28693489
Wang HK et al. Clinical features and molecular characteristics of childhood community-associated methicillin-resistant Staphylococcus aureus infection in a medical center in northern Taiwan, 2012. 2017 BMC Infect. Dis. pmid:28679429
Haynes KM et al. Identification and Structure-Activity Relationships of Novel Compounds that Potentiate the Activities of Antibiotics in Escherichia coli. 2017 J. Med. Chem. pmid:28650638
Dalal A et al. Interventions for the prevention of recurrent erysipelas and cellulitis. 2017 Cochrane Database Syst Rev pmid:28631307
Štšepetova J et al. Assessment of phenotypic and genotypic antibiotic susceptibility of vaginal Lactobacillus sp. 2017 J. Appl. Microbiol. pmid:28574626
Tanaka Y et al. Applicability of ribosome engineering to vitamin B12 production by Propionibacterium shermanii. 2017 Biosci. Biotechnol. Biochem. pmid:28532245
Demczuk WHB et al. Phylogenetic analysis of emergent Streptococcus pneumoniae serotype 22F causing invasive pneumococcal disease using whole genome sequencing. 2017 PLoS ONE pmid:28531208
Cheled-Shoval S et al. From Cell to Beak: In-Vitro and In-Vivo Characterization of Chicken Bitter Taste Thresholds. 2017 Molecules pmid:28513558
Calle-Miguel L et al. [Resistance rates and phenotypic characterization of Streptococcus pyogenes in a paediatric population in Northern Spain (2005-2015)]. 2017 Rev Esp Quimioter pmid:28233483
Selwood DL Macrocycles, the edge of drug-likeness chemical space or Goldilocks zone? 2017 Chem Biol Drug Des pmid:28205398
Pergola S et al. Genetic diversity and antimicrobial resistance profiles of Campylobacter coli and Campylobacter jejuni isolated from broiler chicken in farms and at time of slaughter in central Italy. 2017 J. Appl. Microbiol. pmid:28194914
Huang YW et al. Overexpression of SmeDEF Efflux Pump Decreases Aminoglycoside Resistance in Stenotrophomonas maltophilia. 2017 Antimicrob. Agents Chemother. pmid:28193669
Liu J et al. Engineering of an Lrp family regulator SACE_Lrp improves erythromycin production in Saccharopolyspora erythraea. 2017 Metab. Eng. pmid:27794466
Marlow N et al. The ORACLE Children Study: educational outcomes at 11 years of age following antenatal prescription of erythromycin or co-amoxiclav. 2017 Arch. Dis. Child. Fetal Neonatal Ed. pmid:27515985
Ksia S et al. Molecular Characteristics of Erythromycin-Resistant Streptococcus pyogenes Strains Isolated from Children Patients in Tunis, Tunisia. 2017 Microb. Drug Resist. pmid:27991848
Olajuyigbe OO et al. In vitro pharmacological interaction of caffeine and first-line antibiotics is antagonistic against clinically important bacterial pathogens. 2017 Acta Biochim. Pol. pmid:28612062
Pfaller MA et al. Ceftaroline Activity Against Multidrug-Resistant Streptococcus pneumoniae from U.S. Medical Centers (2014) and Molecular Characterization of a Single Ceftaroline Nonsusceptible Isolate. 2017 Microb. Drug Resist. pmid:27918694
Chang KH et al. Comparison of antibiotic regimens in preterm premature rupture of membranes: neonatal morbidity and 2-year follow-up of neurologic outcome. 2017 J. Matern. Fetal. Neonatal. Med. pmid:27687157
Weber JM et al. Application of In Vitro Transposon Mutagenesis to Erythromycin Strain Improvement in Saccharopolyspora erythraea. 2017 Methods Mol. Biol. pmid:27709581
Hong M et al. C-assisted metabolomics analysis reveals the positive correlation between specific erythromycin production rate and intracellular propionyl-CoA pool size in Saccharopolyspora erythraea. 2017 Bioprocess Biosyst Eng pmid:28567527
Na HK et al. Erythromycin infusion prior to endoscopy for acute nonvariceal upper gastrointestinal bleeding: a pilot randomized controlled trial. 2017 Korean J. Intern. Med. pmid:28352063
Li LH et al. [Effect of low dose erythromycin on the proliferation of granulation tissue after tracheal injury]. 2017 Zhonghua Yi Xue Za Zhi pmid:28316160
Fohner AE et al. PharmGKB summary: Macrolide antibiotic pathway, pharmacokinetics/pharmacodynamics. 2017 Pharmacogenet. Genomics pmid:28146011
Sun H et al. Mechanism Underlying Time-dependent Cross-phenomenon between Concentration-response Curves and Concentration Addition Curves: A Case Study of Sulfonamides-Erythromycin mixtures on Escherichia coli. 2016 Sci Rep pmid:27644411
Mombelli A et al. Effect of Periodontal Therapy With Amoxicillin-Metronidazole on Pharyngeal Carriage of Penicillin- and Erythromycin-Resistant Viridans Streptococci. 2016 J. Periodontol. pmid:26654350
Ulanovsky I et al. Erythromycin Prophylaxis for Neonatal Conjunctivitis: Ointment Versus Drops. 2016 Isr. Med. Assoc. J. pmid:28471562
Sagkan-Ozturk A et al. Prokinetics stimulate the increase of ghrelin in mice. 2016 Bratisl Lek Listy pmid:28127970
Caumes E et al. [Lymphogranuloma venereum]. 2016 Ann Dermatol Venereol pmid:27773504
Aslantaş Ö and Demir C Investigation of the antibiotic resistance and biofilm-forming ability of Staphylococcus aureus from subclinical bovine mastitis cases. 2016 J. Dairy Sci. pmid:27592437
Budha NR et al. Evaluation of Cytochrome P450 3A4-Mediated Drug-Drug Interaction Potential for Cobimetinib Using Physiologically Based Pharmacokinetic Modeling and Simulation. 2016 Clin Pharmacokinet pmid:27225997
Ben Salem I et al. Removal of Penicillin G and Erythromycin with Ionizing Radiation Followed by Biological Treatment. 2016 Curr. Microbiol. pmid:27447798
Wu L et al. Development of Novel Erythromycin Derivatives with Inhibitory Activity against Proliferation of Tumor Cells. 2016 PLoS ONE pmid:27447724
Kwon JW Environmental impact assessment of veterinary drug on fish aquaculture for food safety. 2016 Drug Test Anal pmid:27443211
Cui B et al. Selection of suitable reference genes for gene expression studies in Staphylococcus capitis during growth under erythromycin stress. 2016 Mol. Genet. Genomics pmid:27000656
Zhang A et al. Molecular subtyping and erythromycin resistance of Campylobacter in China. 2016 J. Appl. Microbiol. pmid:26999516
Mukai S et al. Macrolides sensitize EGFR-TKI-induced non-apoptotic cell death via blocking autophagy flux in pancreatic cancer cell lines. 2016 Int. J. Oncol. pmid:26718641
Sousa M et al. Genetic Diversity and Antibiotic Resistance Among Coagulase-Negative Staphylococci Recovered from Birds of Prey in Portugal. 2016 Microb. Drug Resist. pmid:26990729
Morroni G et al. Enterococcus faecium ST17 from Coastal Marine Sediment Carrying Transferable Multidrug Resistance Plasmids. 2016 Microb. Drug Resist. pmid:26982016
Topp E et al. Reduced persistence of the macrolide antibiotics erythromycin, clarithromycin and azithromycin in agricultural soil following several years of exposure in the field. 2016 Sci. Total Environ. pmid:27096634
Li X et al. Macrolides use and the risk of sudden cardiac death. 2016 Expert Rev Anti Infect Ther pmid:27086751
Barros RR et al. Polyclonal spread of Streptococcus agalactiae resistant to clindamycin among pregnant women in Brazil. 2016 J. Antimicrob. Chemother. pmid:27029847
Entorf M et al. Comparative erythromycin and tylosin susceptibility testing of streptococci from bovine mastitis. 2016 Vet. Microbiol. pmid:26732695
Gupta P et al. Nascent peptide assists the ribosome in recognizing chemically distinct small molecules. 2016 Nat. Chem. Biol. pmid:26727240
Naik KM and Nandibewoor ST Investigation into the interaction of methylparaben and erythromycin with human serum albumin using multispectroscopic methods. 2016 Luminescence pmid:26239839