erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Knottenbelt DC | Rhodococcus equi infection in foals: a report of an outbreak on a thoroughbred stud in Zimbabwe. | 1993 | Vet. Rec. | pmid:8438546 |
Bertschinger HU | Antibiotic resistance. | 1989 | Vet. Rec. | pmid:2919499 |
Counter DE | A severe outbreak of bovine mastitis assoicated with Mycoplasma bovigenitalium and Acholeplasma laidlawii. | 1978 | Vet. Rec. | pmid:695253 |
Hillidge CJ | Review of Corynebacterium (Rhodococcus) equi lung abscesses in foals: pathogenesis, diagnosis and treatment. | 1986 | Vet. Rec. | pmid:3535227 |
Edmondson PW | An economic justification of "blitz" therapy to eradicate Streptococcus agalactiae from a dairy herd. | 1989 | Vet. Rec. | pmid:2514481 |
Hartog BJ et al. | Systemic bioavailability of erythromycin in cattle when applied by footbath. | 2001 | Vet. Rec. | pmid:11465266 |
Davies P et al. | Erythromycin resistance of Campylobacter isolates from pigs. | 1996 | Vet. Rec. | pmid:8883355 |
Barber DM | Foot rot in sheep. | 1979 | Vet. Rec. | pmid:516357 |
Laven RA and Proven MJ | Use of an antibiotic footbath in the treatment of bovine digital dermatitis. | 2000 | Vet. Rec. | pmid:11110490 |
Stansfield DG et al. | Campylobacter gastroenteritis in fattening lambs. | 1986 | Vet. Rec. | pmid:3716165 |
Kelmer G et al. | Evaluation of indwelling intravenous catheters for the regional perfusion of the limbs of horses. | 2009 | Vet. Rec. | pmid:19855112 |
Denholm TC | Osteomyelitis in a puppy. | 1966 | Vet. Rec. | pmid:6006976 |
Swarbrick O | The use of parenteral erythromycin in the treatment of bovine mastitis. | 1966 | Vet. Rec. | pmid:6008460 |
Usui M et al. | Selection of macrolide-resistant Campylobacter in pigs treated with macrolides. | 2014 | Vet. Rec. | pmid:25163817 |
Johnston WS | Eradication of STR agalactiae from infected herds using erythromycin. | 1975 | Vet. Rec. | pmid:1094673 |
Hurd DR | Pigeon conditions. | 1991 | Vet. Rec. | pmid:1926717 |
Lacey RW | Rarity of tylosin resistance in human pathogenic bacteria. | 1988 | Vet. Rec. | pmid:3293307 |
Kelmer G and Hayes ME | Regional limb perfusion with erythromycin for treatment of septic physitis and arthritis caused by Rhodococcus equi. | 2009 | Vet. Rec. | pmid:19734562 |
Bradley AJ and Green MJ | Clinical mastitis in dairy cows after 'blitz' therapy. | 1997 | Vet. Rec. | pmid:9290201 |
Laven RA | Efficacy of systemic cefquinome and erythromycin against digital dermatitis in cattle. | 2006 | Vet. Rec. | pmid:16816157 |
Gray JE | Drug-induced enteropathy characterized by lipid in macrophages. | 1975 | Vet. Pathol. | pmid:1166589 |
Marks SL and Kather EJ | Antimicrobial susceptibilities of canine Clostridium difficile and Clostridium perfringens isolates to commonly utilized antimicrobial drugs. | 2003 | Vet. Microbiol. | pmid:12742714 |
Berghaus LJ et al. | Mutant prevention concentration and mutant selection window for 10 antimicrobial agents against Rhodococcus equi. | 2013 | Vet. Microbiol. | pmid:23915992 |
Buchanan AM | Atypical colony-like structures developing in control media and in clinical L-form cultures containing serum. | 1982 | Vet. Microbiol. | pmid:7101718 |
Aarestrup FM et al. | Antimicrobial susceptibility and presence of resistance genes in staphylococci from poultry. | 2000 | Vet. Microbiol. | pmid:10831857 |
Tanner AC et al. | Adaptation of the Sensititre broth microdilution technique to antimicrobial susceptibility testing of Mycoplasma hyopneumoniae. | 1993 | Vet. Microbiol. | pmid:8273275 |
Wasteson Y et al. | Characterization of tetracycline and erythromycin resistance in Actinobacillus pleuropneumoniae. | 1996 | Vet. Microbiol. | pmid:8701576 |
Schmidtke LM and Carson J | Induction, characterisation and pathogenicity in rainbow trout Oncorhynchus mykiss (Walbaum) of Lactococcus garvieae L-forms. | 1999 | Vet. Microbiol. | pmid:10535774 |
Stegmann R and Perreten V | Antibiotic resistance profile of Staphylococcus rostri, a new species isolated from healthy pigs. | 2010 | Vet. Microbiol. | pmid:20399039 |
Hillidge CJ | Use of erythromycin-rifampin combination in treatment of Rhodococcus equi pneumonia. | 1987 | Vet. Microbiol. | pmid:3314109 |
Juntunen P et al. | Longitudinal on-farm study of the development of antimicrobial resistance in Campylobacter coli from pigs before and after danofloxacin and tylosin treatments. | 2011 | Vet. Microbiol. | pmid:21397412 |
Carson J and Statham P | The inhibition by ionophores in vitro of an Enterococcus-like pathogen of rainbow trout, Oncorhynchus mykiss. | 1993 | Vet. Microbiol. | pmid:8273272 |
Bilk S et al. | Antimicrobial susceptibilities and occurrence of resistance genes in bovine Helcococcus ovis isolates. | 2011 | Vet. Microbiol. | pmid:21131144 |
Zanoni RG et al. | Occurrence of Helicobacter pullorum in turkeys. | 2011 | Vet. Microbiol. | pmid:21144678 |
Gautier-Bouchardon AV et al. | In vitro development of resistance to enrofloxacin, erythromycin, tylosin, tiamulin and oxytetracycline in Mycoplasma gallisepticum, Mycoplasma iowae and Mycoplasma synoviae. | 2002 | Vet. Microbiol. | pmid:12119137 |
de Jong A et al. | Antimicrobial susceptibility of enterococci recovered from healthy cattle, pigs and chickens in nine EU countries (EASSA Study) to critically important antibiotics. | 2018 | Vet. Microbiol. | pmid:29519512 |
Shryock TR et al. | Antimicrobial susceptibility of Moraxella bovis. | 1998 | Vet. Microbiol. | pmid:9646479 |
Bagcigil FA et al. | Occurrence, species distribution, antimicrobial resistance and clonality of methicillin- and erythromycin-resistant staphylococci in the nasal cavity of domestic animals. | 2007 | Vet. Microbiol. | pmid:17270365 |
Entorf M et al. | Comparative erythromycin and tylosin susceptibility testing of streptococci from bovine mastitis. | 2016 | Vet. Microbiol. | pmid:26732695 |
Avrain L et al. | Antimicrobial resistance in Campylobacter from broilers: association with production type and antimicrobial use. | 2003 | Vet. Microbiol. | pmid:14559174 |
Roberts MC and Brown MB | Macrolide-lincosamide resistance determinants in streptococcal species isolated from the bovine mammary gland. | 1994 | Vet. Microbiol. | pmid:7941290 |
Kibenge FS et al. | Lysogeny and other characteristics of Staphylococcus hyicus isolated from chickens. | 1983 | Vet. Microbiol. | pmid:6227124 |
Hauschild T et al. | Characterization of a novel type of MLSB resistance plasmid from Staphylococcus saprophyticus carrying a constitutively expressed erm(C) gene. | 2006 | Vet. Microbiol. | pmid:16487670 |
Albarellos GA et al. | Pharmacokinetics of erythromycin after intravenous, intramuscular and oral administration to cats. | 2011 | Vet. J. | pmid:19854664 |
Haenni M et al. | ermB-mediated erythromycin resistance in Streptococcus uberis from bovine mastitis. | 2011 | Vet. J. | pmid:20667752 |
Hung SW et al. | Antibiotic susceptibility and prevalence of erythromycin ribosomal methylase gene, erm(B) in Streptococcus spp. | 2008 | Vet. J. | pmid:17400007 |
Gao J et al. | Antibiotic resistance of Streptococcus agalactiae from cows with mastitis. | 2012 | Vet. J. | pmid:22627045 |
Smith MA et al. | Evaluation of the clinical efficacy of prokinetic drugs in the management of post-operative ileus: can retrospective data help us? | 2005 | Vet. J. | pmid:15908242 |
Penna B et al. | Species distribution and antimicrobial susceptibility of staphylococci isolated from canine otitis externa. | 2010 | Vet. Dermatol. | pmid:20042036 |
Hall JA and Washabau RJ | Diagnosis and treatment of gastric motility disorders. | 1999 | Vet. Clin. North Am. Small Anim. Pract. | pmid:10202795 |
Constable PD et al. | Evidence-based use of prokinetic drugs for abomasal disorders in cattle. | 2012 | Vet. Clin. North Am. Food Anim. Pract. | pmid:22374117 |
Giguère S | Treatment of Infections Caused by Rhodococcus equi. | 2017 | Vet. Clin. North Am. Equine Pract. | pmid:28161038 |
Vaala WE | Aspects of pharmacology in the neonatal foal. | 1985 | Vet. Clin. North Am. Equine Pract. | pmid:3907767 |
Van Hoogmoed LM et al. | Survey of prokinetic use in horses with gastrointestinal injury. | 2004 May-Jun | Vet Surg | pmid:15104636 |
Wittek T et al. | Effect of preoperative erythromycin or dexamethasone/vitamin C on postoperative abomasal emptying rate in dairy cows undergoing surgical correction of abomasal volvulus. | 2008 | Vet Surg | pmid:19134103 |
Jacobs-Reitsma WF et al. | In vitro susceptibility of Campylobacter and Salmonella isolates from broilers to quinolones, ampicillin, tetracycline, and erythromycin. | 1994 | Vet Q | pmid:7740745 |
Stoianova-ZaÄkova L and Doneva M | [Blood concentrations and anti-Borrelia anserina activity of erythromycin salts in birds]. | 1982 | Vet Med Nauki | pmid:7112926 |
Shishkov N et al. | [Use of erythromycin lactate on poultry]. | 1977 | Vet Med Nauki | pmid:607551 |
Doneva M and Bineva I | [Pharmacokinetic and microbiological studies of Pharmachem erythromycin asparate]. | 1979 | Vet Med Nauki | pmid:120997 |
Sherkov Sh et al. | [Drug premixtures wih erythromycin, oxytetracycline and spectinomycin in spirochetosis in poultry]. | 1980 | Vet Med Nauki | pmid:6451979 |
Shishkov N and Drumev D | [Possible synergic action of some drug combinations against Mycoplasma gallisepticum]. | 1975 | Vet Med Nauki | pmid:128891 |
Vasil' M | [Therapy of clinically apparent forms of mastitis in lactating dairy cows using intra-mammary Sulphamycin (Polfa, PR)]. | 1994 | Vet Med (Praha) | pmid:7975049 |
Lukásová J and Jarchovská H | [Resistance of Staphylococcus-aureus strains, isolated from food, to antibiotics]. | 1979 | Vet Med (Praha) | pmid:111401 |
Vyhnálek J | [Distribution of erythromycin following intramuscular administration in laboratory animals]. | 1978 | Vet Med (Praha) | pmid:102070 |
Moffitt CM | Oral and injectable applications of erythromycin in salmonid fish culture. | 1991 | Vet Hum Toxicol | pmid:1926749 |
Moffitt CM | Field trials of investigational new animal drugs. | 1998 | Vet Hum Toxicol | pmid:9823586 |
Bullock GL and Leek SL | Use of erythromycin in reducing vertical transmission of bacterial kidney disease. | 1986 | Vet Hum Toxicol | pmid:3509648 |
Yeary RA | Systemic toxic effects of chemotherapeutic agents in domestic animals. | 1975 | Vet Clin North Am | pmid:804202 |
Mercer HD | Antimicrobial drugs in food-producing animals. Control mechanisms of governmental agencies. | 1975 | Vet Clin North Am | pmid:47207 |
Riazantsev SV et al. | [Dirithromycin, a new antibiotic in the treatment of pharyngeal inflammation]. | 1995 Sep-Oct | Vestn. Otorinolaringol. | pmid:7502454 |
Folomeev VN | [Protegentin phonophoresis as a method of preoperative preparation in the combined treatment of patients with cicatricial stenoses of the larynx and trachea]. | 1988 Jan-Feb | Vestn. Otorinolaringol. | pmid:3281369 |
Chistiakova IS and Klimakova LD | [Treatment of patients with chronic tonsillitis in isolation of a combination of pathogenic staphylococci and candida fungi from the pharynx]. | 1970 | Vestn. Otorinolaringol. | pmid:5510893 |
FEIGIN GA et al. | [USE OF OIL SUSPENSIONS OF SYNTHOMYCIN AND ERYTHROMYCIN IN THE TREATMENT OF CHRONIC TONSILLITIS]. | 1964 Sep-Oct | Vestn. Otorinolaringol. | pmid:14260400 |
Uglov FG et al. | [The use of antibiotics in surgical practice]. | 1967 | Vestn. Khir. Im. I. I. Grek. | pmid:4304565 |
Akzhigitov GH et al. | [The treatment of traumatic pancreatitis with antibiotics and their secretion with pancreatic juice]. | 1968 | Vestn. Khir. Im. I. I. Grek. | pmid:5729234 |
Afanas'ev BA | [Erythromycin in the treatment of gonorrhea in women]. | 1967 | Vestn Dermatol Venerol | pmid:5611849 |
Topuriia RS | [Therapeutic effectiveness of ericycline in combination with apilac in patients with chronic pyoderma]. | 1983 | Vestn Dermatol Venerol | pmid:6659701 |
DENISENKO VA | [Effecicacy of the peroral use of erythromycin in pyoderma]. | 1962 | Vestn Dermatol Venerol | pmid:14026998 |
DENISENKO VS | [Erythromycin treatment of purulent diseases of the skin and subcutaneous tissue]. | 1963 | Vestn Dermatol Venerol | pmid:14026999 |
Lipets ME and Gnidenko VV | [Effectiveness of ericyclin ointment in treating impetigo in children]. | 1986 | Vestn Dermatol Venerol | pmid:3716585 |
Meshkov AM | [Treatment of urogenital chlamydiosis and ureaplasmosis with erycycline combined with diucifon (clinico-electron-microscopy study)]. | 1986 | Vestn Dermatol Venerol | pmid:3825282 |
Vasil'ev TV et al. | [Immediate results of the comprehensive treatment of infectious forms of syphilis with erythromycin, bismuth and nonspecific preparations]. | 1978 | Vestn Dermatol Venerol | pmid:360681 |
Il'in II | [Erythromycin in the therapy of inguinal lymphogranuloma]. | 1966 | Vestn Dermatol Venerol | pmid:5993752 |
Lopatin AI | [Remote results of erythromycin therapy of nongonococcal inflammatory diseases of the urogenital organs]. | 1966 | Vestn Dermatol Venerol | pmid:6002992 |
Bukharovich AM et al. | [Treatment of chronic ulcerative-vegetative pyoderma with ericyclin and levamisole]. | 1985 | Vestn Dermatol Venerol | pmid:4036297 |
AFANAS'EV BA | [Experience in the use of erythromycin in the treatment of acute gonorrhea in men]. | 1962 | Vestn Dermatol Venerol | pmid:13859516 |
Ovchinnikov NM et al. | [Electron microscopic study of gonococcal microstructure in the urethral discharge of gonorrhea patients during penicillin and erythromycin therapy]. | 1973 | Vestn Dermatol Venerol | pmid:4196882 |
SHTEIN AA and DOVZHANSKII SI | [Clinico-bacteriological evaluation of the effectiveness of erythromycin in chronic diffuse strepto-staphyloderma]. | 1962 | Vestn Dermatol Venerol | pmid:13912321 |
Afanas'ev BA | [Erythromycin sensitivity of gonococcal strains isolated in 1965-1966 and in 1971]. | 1973 | Vestn Dermatol Venerol | pmid:4202027 |
Kuntsevich LD | [Erythromycin and oleandomycin in therapy of fresh gonorrhea in women]. | 1968 | Vestn Dermatol Venerol | pmid:5738081 |
Studnitsin AA and Pashkov BM | [Results of discussions on the treatment of syphilis]. | 1968 | Vestn Dermatol Venerol | pmid:5742374 |
Vinokurov IN et al. | [Late results in treating syphilis patients by reserve methods]. | 1988 | Vestn Dermatol Venerol | pmid:3176684 |
Vasil'ev TV et al. | [Immediate results of treatment of syphilis with erythromycin simultaneously with bismuth preparations]. | 1976 | Vestn Dermatol Venerol | pmid:1020453 |
MiliavskiÄ AI and Kostenko AM | [Early prevention of syphilis (experimental study)]. | 1976 | Vestn Dermatol Venerol | pmid:1020461 |
Filatov GI | [Treatment of erysipeloid Rosenbach with erythromycin]. | 1966 | Vestn Dermatol Venerol | pmid:5989838 |
Topuriia RS | [Combined method of relapse-preventing treatment of chronic pyoderma patients]. | 1984 | Vestn Dermatol Venerol | pmid:6730670 |
Rotanov SV | [Use of erythromycin phosphate in treating experimental syphilis in rabbits]. | 1984 | Vestn Dermatol Venerol | pmid:6720078 |
Fedorova LG et al. | [Results of study of the sensitivity of gonococci to combinations of certain antibiotics]. | 1973 | Vestn Dermatol Venerol | pmid:4205737 |
Matsumoto K | New approaches to Pseudomonas aeruginosa lower respiratory tract infections. | 1995 | Verh. K. Acad. Geneeskd. Belg. | pmid:7571853 |
Depoortere I | Motilin and motilin receptors: characterization and functional significance. | 2001 | Verh. K. Acad. Geneeskd. Belg. | pmid:11813507 |