erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Scarlet Fever D012541 1 associated lipids
Pilonidal Sinus D010864 1 associated lipids
Postoperative Nausea and Vomiting D020250 1 associated lipids
Vagus Nerve Injuries D061223 1 associated lipids
Focal Infection, Dental D005491 1 associated lipids
Maxillofacial Injuries D008446 1 associated lipids
Dacryocystitis D003607 1 associated lipids
Erythrasma D004894 1 associated lipids
Granuloma, Respiratory Tract D015769 1 associated lipids
Lymphoma, B-Cell, Marginal Zone D018442 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Authors Title Published Journal PubMed Link
MARTIN WJ et al. The present status of erythromycin. 1953 Proc Staff Meet Mayo Clin pmid:13112261
PERLMAN D Colorimetric method for determination of aureomycin, carbomycin, erythromycin, and terramycin in aqueous solution. 1953 Science pmid:13113207
TALLEY RW Clinical evaluation of erythromycin. 1953 South. Med. J. pmid:13113414
HEDENIUS P and TUNEVALL HG [Erythromycin, its antibacterial effect in vitro, its absorption and excretion, with a preliminary report on a series of cases with erythromycin therapy]. 1953 Sven Lakartidn pmid:13113605
LEVADITI C et al. [Erythromycin; new antibiotic derived from Streptomyces erythreus]. 1953 Ann Inst Pasteur (Paris) pmid:13148738
PARIS J [Severe recurrent intestinal infection due to pathogenic Staphylococcus aureus treated with various antibiotics; favorable effect of erythromycin]. 1953 Arch Mal Appar Dig Mal Nutr pmid:13149270
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KIRBY WM et al. Erythromycin serum concentrations following administration in acid-resistant tablets. 1953 Antibiot Chemother (Northfield) pmid:24542409
JONES PN et al. Use of antibiotics in nonbacterial respiratory infections. 1953 J Am Med Assoc pmid:13084382
KIRSHBAUM A et al. A cupplate method for the determination of erythromycin concentrations in serum and other body fluids. 1953 Antibiot Chemother (Northfield) pmid:24542421
ROMANSKY MJ Current trends in antibiotic therapy. 1953 Med Bull US Army Eur pmid:13085979
CLARK RK The chemistry of erythromycin. I. Acid degradation products. 1953 Antibiot Chemother (Northfield) pmid:24542535
FABRE J [A new antibiotic: erythromycin; its therapeutic effect in 60 cases of various diseases]. 1953 Praxis pmid:13088584
MAPLE FM et al. Serum concentrations of erythromycin following intravenous administration. 1953 Antibiot Chemother (Northfield) pmid:24542586
BUNN PA and COOK E Treatment of pneumococcal pneumonia with erythromycin and carbomycin (magnamycin). 1953 AMA Arch Intern Med pmid:13091455
NESERKE EI Clinical report on the new antibiotic, erythromycin. 1953 J. Am. Vet. Med. Assoc. pmid:13061363
GABLE GR et al. Treatment of gonorrhea with erythromycin. 1953 Am J Syph Gonorrhea Vener Dis pmid:13065617
HERRELL WE et al. Erythromycin for infections due to Micrococcus pyogenes. 1953 J Am Med Assoc pmid:13069224
ROBINSON HM and ZELIGMAN I Erythromycin ointment in the treatment of the pyodermas. 1953 J. Invest. Dermatol. pmid:13069824
ROBINSON HM and COHEN MM Treatment of granuloma inguinale with erythromycin. 1953 J. Invest. Dermatol. pmid:13069825
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LUND E [Erythromycin, a new antibiotic]. 1953 Ugeskr. Laeg. pmid:13136562
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ANDERSON RC et al. The toxicity and distribution of ilotycin. 1952 J Am Pharm Assoc Am Pharm Assoc pmid:12999613
ERYTHROMYCIN, new and promising antibiotic. 1952 N. Engl. J. Med. pmid:14947939
HAIGHT TH and FINLAND M Laboratory and clinical studies on erythromycin. 1952 N. Engl. J. Med. pmid:14947931
ERYTHROMYCIN: another antibiotic. 1952 Lancet pmid:14939901
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Bottega A et al. Evaluation of constitutive and inducible resistance to clindamycin in clinical samples of Staphylococcus aureus from a tertiary hospital. Rev. Soc. Bras. Med. Trop. pmid:25467260
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Zhou W et al. Erythromycin-resistant genes in group A β-haemolytic Streptococci in Chengdu, Southwestern China. Indian J Med Microbiol pmid:25008823
Abraham T and Sistla S Trends in antimicrobial resistance patterns of Group A streptococci, molecular basis and implications. Indian J Med Microbiol pmid:30084408
Cai C et al. Effects of erythromycin on γ-glutamyl cysteine synthetase and interleukin-1β in hyperoxia-exposed lung tissue of premature newborn rats. J Pediatr (Rio J) pmid:24878007
pmid:
Pranteda G et al. Pitted keratolysis, erythromycin, and hyperhidrosis. Dermatol Ther pmid:24703267
Wang X et al. Phenotypic and molecular characterization of Streptococcus agalactiae colonized in Chinese pregnant women: predominance of ST19/III and ST17/III. Res. Microbiol. pmid:29378338
Yayan J and Rasche K Growing Antibiotic Resistance in Fatal Cases of Staphylococcal Pneumonia in the Elderly. Adv. Exp. Med. Biol. pmid:26747068
Alvarez-Sánchez M et al. [Bacterial resistance in acne? A meta-analysis of the controversy]. Cir Cir pmid:26738649
Mondragón-Navarro M et al. Potential association between erythromycin and cholestatic hepatitis. Med Intensiva pmid:26707838
Jahansepas A et al. Occurrence of Enterococcus faecalis and Enterococcus faecium in Various Clinical Infections: Detection of Their Drug Resistance and Virulence Determinants. Microb. Drug Resist. pmid:28525287
Silva V et al. Genetic Characterization of vanA-Enterococcus faecium Isolates from Wild Red-Legged Partridges in Portugal. Microb. Drug Resist. pmid:28504889
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Commerford PJ From the Editor's Desk. Cardiovasc J Afr pmid:26592903
Fallahpour N et al. Overproduction of Erythromycin by Ultraviolet Mutagenesis and Expression of ermE Gene in Saccharopolyspora erythraea. Assay Drug Dev Technol pmid:29120674