erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Rat-Bite Fever D011906 1 associated lipids
Pelvic Infection D034161 1 associated lipids
Prolapse D011391 1 associated lipids
Compartment Syndromes D003161 1 associated lipids
Fecal Incontinence D005242 1 associated lipids
Gastric Outlet Obstruction D017219 1 associated lipids
Hematemesis D006396 1 associated lipids
Carbuncle D002270 1 associated lipids
Erysipelas D004886 1 associated lipids
Gas Gangrene D005738 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Authors Title Published Journal PubMed Link
Karlsson M et al. Genetic basis of macrolide and lincosamide resistance in Brachyspira (Serpulina) hyodysenteriae. 1999 FEMS Microbiol. Lett. pmid:10188254
Kinirons MT et al. Effects of ketoconazole on the erythromycin breath test and the dapsone recovery ratio. 1999 Br J Clin Pharmacol pmid:10190659
Mthwalo M et al. Antibiotic resistance of nasopharyngeal isolates of Streptococcus pneumoniae from children in Lesotho. 1998 Bull. World Health Organ. pmid:10191560
Isohanni MH et al. Effect of erythromycin and itraconazole on the pharmacokinetics of oral lignocaine. 1999 Pharmacol. Toxicol. pmid:10193676
Stenson BJ et al. Influence of erythromycin on establishment of feeding in preterm infants: observations from a randomised controlled trial. 1998 Arch. Dis. Child. Fetal Neonatal Ed. pmid:10194995
Dorner S and Barta A Probing ribosome structure by europium-induced RNA cleavage. 1999 Biol. Chem. pmid:10195431
Montenez JP et al. Interactions of macrolide antibiotics (Erythromycin A, roxithromycin, erythromycylamine [Dirithromycin], and azithromycin) with phospholipids: computer-aided conformational analysis and studies on acellular and cell culture models. 1999 Toxicol. Appl. Pharmacol. pmid:10198278
Sakaeva DD and Lazareva DN [The effect of erythromycin on immunity in immunodeficiency]. 1999 Jan-Feb Eksp Klin Farmakol pmid:10198768
Jarrett F et al. Antibiotic bowel preparation and burn wound colonization. 1976 Surg Forum pmid:1019996
Scarpignato C and Pelosini I Management of irritable bowel syndrome: novel approaches to the pharmacology of gut motility. 1999 Can. J. Gastroenterol. pmid:10202210