erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Endocarditis, Subacute Bacterial D004698 1 associated lipids
Choanal Atresia D002754 1 associated lipids
Lacrimal Duct Obstruction D007767 1 associated lipids
Scarlet Fever D012541 1 associated lipids
Maxillofacial Injuries D008446 1 associated lipids
Dacryocystitis D003607 1 associated lipids
Erythrasma D004894 1 associated lipids
Granuloma, Respiratory Tract D015769 1 associated lipids
Pilonidal Sinus D010864 1 associated lipids
Postoperative Nausea and Vomiting D020250 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Authors Title Published Journal PubMed Link
Huang M et al. Single nucleotide polymorphism of CYP3A4 intron 2 and its influence on CYP3A4 mRNA expression and liver enzymatic activity in human liver. 2015 J. Huazhong Univ. Sci. Technol. Med. Sci. pmid:26223917
Schneider SC et al. Antibiotic Susceptibility and Sequence Type Distribution of Ureaplasma Species Isolated from Genital Samples in Switzerland. 2015 Antimicrob. Agents Chemother. pmid:26195516
Takagi M et al. Underlying mechanism of drug-drug interaction between pioglitazone and gemfibrozil: Gemfibrozil acyl-glucuronide is a mechanism-based inhibitor of CYP2C8. 2015 Drug Metab. Pharmacokinet. pmid:26195223
Aydin S et al. Development of antibiotic resistance genes in microbial communities during long-term operation of anaerobic reactors in the treatment of pharmaceutical wastewater. 2015 Water Res. pmid:26188597
Gaudreau C et al. Long-Lasting Outbreak of Erythromycin- and Ciprofloxacin-Resistant Campylobacter jejuni Subspecies jejuni From 2003 to 2013 in Men Who Have Sex With Men, Quebec, Canada. 2015 Clin. Infect. Dis. pmid:26187024
Fayed B et al. Multiplexed integrating plasmids for engineering of the erythromycin gene cluster for expression in Streptomyces spp. and combinatorial biosynthesis. 2015 Appl. Environ. Microbiol. pmid:26431970
Vlakh EG et al. Preparation and characterization of macroporous monoliths imprinted with erythromycin. 2015 J Sep Sci pmid:26033867
Wang L et al. Changes in diversity of cultured bacteria resistant to erythromycin and tetracycline in swine manure during simulated composting and lagoon storage. 2015 Lett. Appl. Microbiol. pmid:26031793
Wang Z et al. MicroRNA 21 is a homeostatic regulator of macrophage polarization and prevents prostaglandin E2-mediated M2 generation. 2015 PLoS ONE pmid:25706647
Yoon IA et al. Clinical significance of serotype V among infants with invasive group B streptococcal infections in South Korea. 2015 Int. J. Infect. Dis. pmid:26026823
Gherardi G et al. Decline in macrolide resistance rates among Streptococcus pyogenes causing pharyngitis in children isolated in Italy. 2015 Eur. J. Clin. Microbiol. Infect. Dis. pmid:26024763
Reveiz L and Cardona AF Antibiotics for acute laryngitis in adults. 2015 Cochrane Database Syst Rev pmid:26002823
Pesola AK et al. Clindamycin resistant emm33 Streptococcus pyogenes emerged among invasive infections in Helsinki metropolitan area, Finland, 2012 to 2013. 2015 Euro Surveill. pmid:25990232
Sun XJ et al. Combination of erythromycin and dexamethasone improves corticosteroid sensitivity induced by CSE through inhibiting PI3K-δ/Akt pathway and increasing GR expression. 2015 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:25957293
Guo MT et al. Insights into the amplification of bacterial resistance to erythromycin in activated sludge. 2015 Chemosphere pmid:25957255
Hersch M et al. Prokinetic drugs for gastric emptying in critically ill ventilated patients: Analysis through breath testing. 2015 J Crit Care pmid:25746849
Lee S et al. Functional analysis of Vibrio vulnificus RND efflux pumps homologous to Vibrio cholerae VexAB and VexCD, and to Escherichia coli AcrAB. 2015 J. Microbiol. pmid:25740377
Lysnyansky I et al. Decreased Susceptibility to Macrolide-Lincosamide in Mycoplasma synoviae Is Associated with Mutations in 23S Ribosomal RNA. 2015 Microb. Drug Resist. pmid:25734368
Abreu AC et al. Combinatorial Activity of Flavonoids with Antibiotics Against Drug-Resistant Staphylococcus aureus. 2015 Microb. Drug Resist. pmid:25734256
Ou H et al. Selective removal of erythromycin by magnetic imprinted polymers synthesized from chitosan-stabilized Pickering emulsion. 2015 J. Hazard. Mater. pmid:25704432
Ikebe T et al. Increased prevalence of group A streptococcus isolates in streptococcal toxic shock syndrome cases in Japan from 2010 to 2012. 2015 Epidemiol. Infect. pmid:25703404
Li Y et al. Where macrolide resistance is prevalent. 2015 APMIS pmid:25703275
Chemler JA et al. Evolution of Efficient Modular Polyketide Synthases by Homologous Recombination. 2015 J. Am. Chem. Soc. pmid:26230368
Choi JH et al. Distribution of emm types among group A Streptococcus isolates from children in Korea. 2015 Diagn. Microbiol. Infect. Dis. pmid:25700867
Luo H et al. Identification of ribosomal RNA methyltransferase gene ermF in Riemerella anatipestifer. 2015 Avian Pathol. pmid:25690020
Sessa R et al. Effects of Mentha suaveolens essential oil on Chlamydia trachomatis. 2015 Biomed Res Int pmid:25685793
Nagelreiter C et al. Dilution of semi-solid creams: influence of various production parameters on rheological properties and skin penetration. 2015 Int J Pharm pmid:25475015
Harmer CJ et al. A type 2 A/C2 plasmid carrying the aacC4 apramycin resistance gene and the erm(42) erythromycin resistance gene recovered from two Salmonella enterica serovars. 2015 J. Antimicrob. Chemother. pmid:25468903
Wan J et al. Effect of erythromycin exposure on the growth, antioxidant system and photosynthesis of Microcystis flos-aquae. 2015 J. Hazard. Mater. pmid:25464321
Zhou Z et al. Macrolide-resistant Mycoplasma pneumoniae in adults in Zhejiang, China. 2015 Antimicrob. Agents Chemother. pmid:25451048
Hur J et al. Systems pharmacological analysis of drugs inducing stevens-johnson syndrome and toxic epidermal necrolysis. 2015 Chem. Res. Toxicol. pmid:25811541
Haxel BR et al. Controlled trial for long-term low-dose erythromycin after sinus surgery for chronic rhinosinusitis. 2015 Laryngoscope pmid:25425539
Berg C et al. Significance of archaeal nitrification in hypoxic waters of the Baltic Sea. 2015 ISME J pmid:25423026
Siekmeier R et al. Inhalation of macrolides: a novel approach to treatment of pulmonary infections. 2015 Adv. Exp. Med. Biol. pmid:25252902
Chen Y et al. The glucose RQ-feedback control leading to improved erythromycin production by a recombinant strain Saccharopolyspora erythraea ZL1004 and its scale-up to 372-m(3) fermenter. 2015 Bioprocess Biosyst Eng pmid:25042891
Llorca M et al. Identification of new transformation products during enzymatic treatment of tetracycline and erythromycin antibiotics at laboratory scale by an on-line turbulent flow liquid-chromatography coupled to a high resolution mass spectrometer LTQ-Orbitrap. 2015 Chemosphere pmid:24972175
Mazur CS et al. P-glycoprotein inhibition by the agricultural pesticide propiconazole and its hydroxylated metabolites: Implications for pesticide-drug interactions. 2015 Toxicol. Lett. pmid:25268938
Song LY et al. Exploring Synergy between Classic Mutagens and Antibiotics To Examine Mechanisms of Synergy and Antibiotic Action. 2015 Antimicrob. Agents Chemother. pmid:26711761
Cochrane SA et al. Synthesis of Tridecaptin-Antibiotic Conjugates with in Vivo Activity against Gram-Negative Bacteria. 2015 J. Med. Chem. pmid:26636619
Wilson DW et al. Macrolides rapidly inhibit red blood cell invasion by the human malaria parasite, Plasmodium falciparum. 2015 BMC Biol. pmid:26187647
Fedashchin A et al. Random transposon mutagenesis of the Saccharopolyspora erythraea genome reveals additional genes influencing erythromycin biosynthesis. 2015 FEMS Microbiol. Lett. pmid:26468041
Yi X et al. Improved detection of multiple environmental antibiotics through an optimized sample extraction strategy in liquid chromatography-mass spectrometry analysis. 2015 Anal Bioanal Chem pmid:26449847
Ayazi P et al. Tick-borne Relapsing Fever in Children in the North-west of Iran, Qazvin. 2015 Prague Med Rep pmid:26445390
Yamaguchi M et al. Calcitonin Receptor Signaling Inhibits Muscle Stem Cells from Escaping the Quiescent State and the Niche. 2015 Cell Rep pmid:26440893
Chazan B et al. Susceptibility of Group A Streptococcus to Antimicrobial Agents in Northern Israel: A Surveillance Study. 2015 Microb. Drug Resist. pmid:26430943
Hoffmann K et al. Prevalence and resistance patterns of commensal S. aureus in community-dwelling GP patients and socio-demographic associations. A cross-sectional study in the framework of the APRES-project in Austria. 2015 BMC Infect. Dis. pmid:25981559
Peyre L et al. High-content screening imaging and real-time cellular impedance monitoring for the assessment of chemical's bio-activation with regards hepatotoxicity. 2015 Toxicol In Vitro pmid:26239606
Banik A et al. Inducible and constitutive clindamycin resistance in Staphylococcus aureus in a northeastern Indian tertiary care hospital. 2015 J Infect Dev Ctries pmid:26230122
Wang Z et al. Direct Detection of Erythromycin-Resistant Bordetella pertussis in Clinical Specimens by PCR. 2015 J. Clin. Microbiol. pmid:26224847
Olivieri R et al. Evolution of macrolide resistance in Streptococcus pyogenes over 14 years in an area of central Italy. 2015 J. Med. Microbiol. pmid:26224594