| MeSH term | MeSH ID | Detail |
|---|---|---|
| Body Weight | D001835 | 333 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Hypertension | D006973 | 115 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Chen C et al. | Blocking the flow of propionate into TCA cycle through a mutB knockout leads to a significant increase of erythromycin production by an industrial strain of Saccharopolyspora erythraea. | 2017 | Bioprocess Biosyst Eng | pmid:27709326 |
| Tran LTC et al. | Erythromycin encapsulation in nanoemulsion-based delivery systems for treatment of Helicobacter pylori infection: Protection and synergy. | 2017 | Biochem. Biophys. Res. Commun. | pmid:28917836 |
| Gonser LI et al. | Systemic therapy of ocular and cutaneous rosacea in children. | 2017 | J Eur Acad Dermatol Venereol | pmid:28621909 |
| Tintino SR et al. | Tannic acid affects the phenotype of Staphylococcus aureus resistant to tetracycline and erythromycin by inhibition of efflux pumps. | 2017 | Bioorg. Chem. | pmid:28841421 |
| Ji W et al. | Colonization prevalence and antibiotic susceptibility of Group B Streptococcus in pregnant women over a 6-year period in Dongguan, China. | 2017 | PLoS ONE | pmid:28813477 |
| Wang D et al. | An analogous wood barrel theory to explain the occurrence of hormesis: A case study of sulfonamides and erythromycin on Escherichia coli growth. | 2017 | PLoS ONE | pmid:28715457 |
| Jia L et al. | Synthesis and antibacterial evaluation of novel 11-O-carbamoyl clarithromycin ketolides. | 2017 | Bioorg. Med. Chem. Lett. | pmid:28711353 |
| Adhikari RP et al. | Inducible clindamycin and methicillin resistant Staphylococcus aureus in a tertiary care hospital, Kathmandu, Nepal. | 2017 | BMC Infect. Dis. | pmid:28693489 |
| Wang HK et al. | Clinical features and molecular characteristics of childhood community-associated methicillin-resistant Staphylococcus aureus infection in a medical center in northern Taiwan, 2012. | 2017 | BMC Infect. Dis. | pmid:28679429 |
| Haynes KM et al. | Identification and Structure-Activity Relationships of Novel Compounds that Potentiate the Activities of Antibiotics in Escherichia coli. | 2017 | J. Med. Chem. | pmid:28650638 |
| Dalal A et al. | Interventions for the prevention of recurrent erysipelas and cellulitis. | 2017 | Cochrane Database Syst Rev | pmid:28631307 |
| Ge LL et al. | [Antibiotic resistance analysis of isolates from the hospitalized children in Shanxi Children's Hospital from 2012 to 2014]. | 2017 | Zhonghua Er Ke Za Zhi | pmid:28173648 |
| Giguère S | Treatment of Infections Caused by Rhodococcus equi. | 2017 | Vet. Clin. North Am. Equine Pract. | pmid:28161038 |
| Wang Y et al. | Evaluation of a series of 2-napthamide derivatives as inhibitors of the drug efflux pump AcrB for the reversal of antimicrobial resistance. | 2017 | Bioorg. Med. Chem. Lett. | pmid:28129976 |
| Descours G et al. | Ribosomal Mutations Conferring Macrolide Resistance in Legionella pneumophila. | 2017 | Antimicrob. Agents Chemother. | pmid:28069647 |
| Owen L et al. | A Multifactorial Comparison of Ternary Combinations of Essential Oils in Topical Preparations to Current Antibiotic Prescription Therapies for the Control of Acne Vulgaris-Associated Bacteria. | 2017 | Phytother Res | pmid:28124400 |
| Chen K et al. | Drug-resistance dynamics of Staphylococcus aureus between 2008 and 2014 at a tertiary teaching hospital, Jiangxi Province, China. | 2017 | BMC Infect. Dis. | pmid:28122513 |
| Berni E et al. | Risk of cardiovascular events, arrhythmia and all-cause mortality associated with clarithromycin versus alternative antibiotics prescribed for respiratory tract infections: a retrospective cohort study. | 2017 | BMJ Open | pmid:28115334 |
| Wei L et al. | Transformation of erythromycin during secondary effluent soil aquifer recharging: Removal contribution and degradation path. | 2017 | J Environ Sci (China) | pmid:28115128 |
| Koryakina I et al. | Inversion of Extender Unit Selectivity in the Erythromycin Polyketide Synthase by Acyltransferase Domain Engineering. | 2017 | ACS Chem. Biol. | pmid:28103677 |
| Kassem II et al. | Antimicrobial-Resistant Campylobacter in Organically and Conventionally Raised Layer Chickens. | 2017 | Foodborne Pathog. Dis. | pmid:27768387 |
| Song KH et al. | Characteristics of cefazolin inoculum effect-positive methicillin-susceptible staphylococcus aureus infection in a multicentre bacteraemia cohort. | 2017 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:27714592 |
| Kullin B et al. | Toxin A-negative toxin B-positive ribotype 017 Clostridium difficile is the dominant strain type in patients with diarrhoea attending tuberculosis hospitals in Cape Town, South Africa. | 2017 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:27696234 |
| Austin BA and Fleischer AB | The extinction of topical erythromycin therapy for acne vulgaris and concern for the future of topical clindamycin. | 2017 | J Dermatolog Treat | pmid:27425633 |
| Jakubů V et al. | Trends in the Minimum Inhibitory Concentrations of Erythromycin, Clarithromycin, Azithromycin, Ciprofloxacin, and Trimethoprim/Sulfamethoxazole for Strains of Bordetella pertussis isolated in the Czech Republic in 1967-2015. | 2017 | Cent. Eur. J. Public Health | pmid:29346850 |
| Romero L et al. | Macrolides for treatment of Haemophilus ducreyi infection in sexually active adults. | 2017 | Cochrane Database Syst Rev | pmid:29226307 |
| Naimi HM et al. | Determination of antimicrobial susceptibility patterns in Staphylococcus aureus strains recovered from patients at two main health facilities in Kabul, Afghanistan. | 2017 | BMC Infect. Dis. | pmid:29187146 |
| Svetlov MS et al. | Kinetics of drug-ribosome interactions defines the cidality of macrolide antibiotics. | 2017 | Proc. Natl. Acad. Sci. U.S.A. | pmid:29229833 |
| Wang B et al. | Acid or erythromycin stress significantly improves transformation efficiency through regulating expression of DNA binding proteins in Lactococcus lactis F44. | 2017 | J. Dairy Sci. | pmid:28987584 |
| Stieler AL et al. | Macrolide-induced hyperthermia in foals: Role of impaired sweat responses. | 2016 | Equine Vet. J. | pmid:26174202 |
| Talebi M et al. | Determination of Characteristics of Erythromycin Resistant Streptococcus pneumoniae with Preferred PCV Usage in Iran. | 2016 | PLoS ONE | pmid:28033345 |
| Li M et al. | Inducible Expression of both ermB and ermT Conferred High Macrolide Resistance in Streptococcus gallolyticus subsp. pasteurianus Isolates in China. | 2016 | Int J Mol Sci | pmid:27669217 |
| Murchison L et al. | Post-natal erythromycin exposure and risk of infantile hypertrophic pyloric stenosis: a systematic review and meta-analysis. | 2016 | Pediatr. Surg. Int. | pmid:27655365 |
| Dzyubak E and Yap MN | The Expression of Antibiotic Resistance Methyltransferase Correlates with mRNA Stability Independently of Ribosome Stalling. | 2016 | Antimicrob. Agents Chemother. | pmid:27645242 |
| Abreu AC et al. | Combinatorial approaches with selected phytochemicals to increase antibiotic efficacy against Staphylococcus aureus biofilms. | 2016 | Biofouling | pmid:27643487 |
| Waiser MJ et al. | Effects of erythromycin, trimethoprim and clindamycin on attached microbial communities from an effluent dominated prairie stream. | 2016 | Ecotoxicol. Environ. Saf. | pmid:27261880 |
| KarniÄar K et al. | Integrated omics approaches provide strategies for rapid erythromycin yield increase in Saccharopolyspora erythraea. | 2016 | Microb. Cell Fact. | pmid:27255285 |
| Ghosh S and Banerjee M | Methicillin resistance & inducible clindamycin resistance in Staphylococcus aureus. | 2016 | Indian J. Med. Res. | pmid:27241651 |
| Pignatello R et al. | Synthesis, characterization and in vitro evaluation of amphiphilic ion pairs of erythromycin and kanamycin antibiotics with liposaccharides. | 2016 | Eur J Med Chem | pmid:27236014 |
| Trac MH et al. | Macrolide antibiotics and the risk of ventricular arrhythmia in older adults. | 2016 | CMAJ | pmid:26903359 |
| Aydin S et al. | Assessment of anaerobic bacterial diversity and its effects on anaerobic system stability and the occurrence of antibiotic resistance genes. | 2016 | Bioresour. Technol. | pmid:26897411 |
| Baek YS et al. | Antimicrobial resistance of Staphylococcus aureus isolated from skin infections and its implications in various clinical conditions in Korea. | 2016 | Int. J. Dermatol. | pmid:26892888 |
| Chua SL et al. | Selective labelling and eradication of antibiotic-tolerant bacterial populations in Pseudomonas aeruginosa biofilms. | 2016 | Nat Commun | pmid:26892159 |
| Liu H et al. | [A systematic review of the therapy for Mycoplasma pneumoniae infections in children]. | 2016 | Zhonghua Er Ke Za Zhi | pmid:26875461 |
| Broad J et al. | RQ-00201894: A motilin receptor agonist causing long-lasting facilitation of human gastric cholinergically-mediated contractions. | 2016 | J. Pharmacol. Sci. | pmid:26685754 |
| Sayed Ahmed WA et al. | Maternal serum interleukin-6 in the management of patients with preterm premature rupture of membranes. | 2016 | J. Matern. Fetal. Neonatal. Med. | pmid:26669630 |
| Vitali LA et al. | Correlation between genetic features of the mef(A)-msr(D) locus and erythromycin resistance in Streptococcus pyogenes. | 2016 | Diagn. Microbiol. Infect. Dis. | pmid:26429294 |
| Sugawara A et al. | Non-antibiotic 12-membered macrolides: design, synthesis and biological evaluation in a cigarette-smoking model. | 2016 | J. Antibiot. | pmid:26419414 |
| Brunel R and Charpentier X | Trans-translation is essential in the human pathogen Legionella pneumophila. | 2016 | Sci Rep | pmid:27892503 |
| Yuan SF et al. | Levels of six antibiotics used in China estimated by means of wastewater-based epidemiology. | 2016 | Water Sci. Technol. | pmid:26901719 |