erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Drug-Related Side Effects and Adverse Reactions D064420 3 associated lipids
Vagus Nerve Injuries D061223 1 associated lipids
Occupational Injuries D060051 1 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Chemical and Drug Induced Liver Injury D056486 39 associated lipids
Acute Lung Injury D055371 33 associated lipids
Atrioventricular Block D054537 1 associated lipids
Pneumonia, Ventilator-Associated D053717 1 associated lipids
Kidney Diseases, Cystic D052177 3 associated lipids
Granulomatosis, Orofacial D051261 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Ball SE et al. Population distribution and effects on drug metabolism of a genetic variant in the 5' promoter region of CYP3A4. 1999 Clin. Pharmacol. Ther. pmid:10511065
Chantarotorn S et al. Diffuse panbronchiolitis, the first case reports in Thailand. 1999 J Med Assoc Thai pmid:10511794
Yoshida H and Furuta T [Tissue penetration properties of macrolide antibiotics--comparative tissue distribution of erythromycin-stearate, clarithromycin, roxithromycin and azithromycin in rats]. 1999 Jpn J Antibiot pmid:10516929
De Winter BY et al. Effect of different prokinetic agents and a novel enterokinetic agent on postoperative ileus in rats. 1999 Gut pmid:10517907
Xue Q et al. A multiplasmid approach to preparing large libraries of polyketides. 1999 Proc. Natl. Acad. Sci. U.S.A. pmid:10518520
Sheu BS et al. A three-day course of intravenous omeprazole plus antibiotics for H. pylori-positive bleeding duodenal ulcer. 1999 Jul-Aug Hepatogastroenterology pmid:10521999
Cocito C and Di Giambattista M The in vitro binding of virginiamycin M to bacteria ribosomes and ribosomal subunits. 1978 Mol. Gen. Genet. pmid:105240
Shortridge VD et al. Prevalence of macrolide resistance mechanisms in Streptococcus pneumoniae isolates from a multicenter antibiotic resistance surveillance study conducted in the United States in 1994-1995. 1999 Clin. Infect. Dis. pmid:10524961
Yoh M et al. Effect of subinhibitory concentrations of antimicrobial agents (quinolones and macrolide) on the production of verotoxin by enterohemorrhagic Escherichia coli O157:H7. 1999 Can. J. Microbiol. pmid:10526400
Sato A et al. Effects of organic anions and vinblastine on biliary excretion of erythromycin in rats. 1999 Pharmacology pmid:10529657
Janier M [Syphilis (except congenital syphilis)]. 1999 Aug-Sep Ann Dermatol Venereol pmid:10530355
Schmidtke LM and Carson J Induction, characterisation and pathogenicity in rainbow trout Oncorhynchus mykiss (Walbaum) of Lactococcus garvieae L-forms. 1999 Vet. Microbiol. pmid:10535774
Nicholas KC et al. Periadenitis mucosa necrotica recurrens. 1975 J Oral Surg pmid:1053656
Tobback K et al. Micellar electrokinetic capillary chromatography of macrolide antibiotics. Separation of tylosin, erythromycin and their related substances. 1999 J Chromatogr A pmid:10536850
Maeda K et al. [A case of common variable immunodeficiency that responded to long-term erythromycin chemotherapy]. 1999 Nihon Kokyuki Gakkai Zasshi pmid:10540836
Aoki Y and Kao PN Erythromycin inhibits transcriptional activation of NF-kappaB, but not NFAT, through calcineurin-independent signaling in T cells. 1999 Antimicrob. Agents Chemother. pmid:10543746
Netherwood T et al. Probiotics shown to change bacterial community structure in the avian gastrointestinal tract. 1999 Appl. Environ. Microbiol. pmid:10543832
Jobe DA et al. Detection of borreliacidal antibodies in Lyme borreliosis patient sera containing antimicrobial agents. 1999 Clin. Diagn. Lab. Immunol. pmid:10548588
Zallen RD and Curry JT A study of antibiotic usage in compound mandibular fractures. 1975 J Oral Surg pmid:1055204
Watanabe M et al. Role of CYP3A in bromperidol metabolism in rat in vitro and in vivo. 1999 Xenobiotica pmid:10553724