erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Drug-Related Side Effects and Adverse Reactions D064420 3 associated lipids
Vagus Nerve Injuries D061223 1 associated lipids
Occupational Injuries D060051 1 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Chemical and Drug Induced Liver Injury D056486 39 associated lipids
Acute Lung Injury D055371 33 associated lipids
Atrioventricular Block D054537 1 associated lipids
Pneumonia, Ventilator-Associated D053717 1 associated lipids
Kidney Diseases, Cystic D052177 3 associated lipids
Granulomatosis, Orofacial D051261 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Authors Title Published Journal PubMed Link
Konturek JW and Domschke W [Gastroparesis--physiopathology, diagnosis and the latest therapy]. 1998 Dtsch. Med. Wochenschr. pmid:9556697
Lilley LL and Guanci R Drug interaction triggers weakness. 1998 Am J Nurs pmid:9556673
Schwarz MI A man with dyspnea, productive cough, and chest radiograph showing hyperinflation and a diffuse nodular pattern. 1998 Chest pmid:9554657
Mortensen JE et al. In vitro activity of oral antimicrobial agents against clinical isolates of Pasteurella multocida. 1998 Diagn. Microbiol. Infect. Dis. pmid:9554176
Mück W et al. Influence of erythromycin pre- and co-treatment on single-dose pharmacokinetics of the HMG-CoA reductase inhibitor cerivastatin. 1998 Eur. J. Clin. Pharmacol. pmid:9551706
Chakrabarti MK et al. Evaluation of different antibiotics in inhibiting colonization of Vibrio cholerae O1 and O139 in the rabbit intestine. 1998 Mar-Apr Chemotherapy pmid:9551241
Sachdeo RC et al. Evaluation of the potential interaction between felbamate and erythromycin in patients with epilepsy. 1998 J Clin Pharmacol pmid:9549651
Tanaka E and Breimer DD In vivo function tests of hepatic drug-oxidizing capacity in patients with liver disease. 1997 J Clin Pharm Ther pmid:9548204
Bertho G et al. Transferred nuclear Overhauser effect study of macrolide-ribosome interactions: correlation between antibiotic activities and bound conformations. 1998 Bioorg. Med. Chem. pmid:9547944
Li YX et al. Sensitive determination of erythromycin in human plasma by LC-MS/MS. 1998 J Pharm Biomed Anal pmid:9547699
Fitzgerald NB et al. Sonication-dependent electroporation of the erythromycin-producing bacterium Saccharopolyspora erythraea. 1998 Appl. Environ. Microbiol. pmid:9546194
Thomas AR et al. Prolongation of the QT interval related to cisapride-diltiazem interaction. 1998 Mar-Apr Pharmacotherapy pmid:9545159
Norcia LJ et al. In vitro microbiological characterization of novel macrolide CP-163,505 for animal health specific use. 1998 J. Antibiot. pmid:9544934
Williamson KM et al. Effects of erythromycin or rifampin on losartan pharmacokinetics in healthy volunteers. 1998 Clin. Pharmacol. Ther. pmid:9542475
Jacobsen JR et al. Spontaneous priming of a downstream module in 6-deoxyerythronolide B synthase leads to polyketide biosynthesis. 1998 Biochemistry pmid:9538011
Lyon AJ et al. Randomised trial of erythromycin on the development of chronic lung disease in preterm infants. 1998 Arch. Dis. Child. Fetal Neonatal Ed. pmid:9536833
Choi MG et al. Dose-related effects of N-demethyl-N-isopropyl-8, 9-anhydroerythromycin A 6,9-hemiacetal on gastric emptying of solids in healthy human volunteers. 1998 J. Pharmacol. Exp. Ther. pmid:9535992
Stout JE et al. Activity of azithromycin, clarithromycin, roxithromycin, dirithromycin, quinupristin/dalfopristin and erythromycin against Legionella species by intracellular susceptibility testing in HL-60 cells. 1998 J. Antimicrob. Chemother. pmid:9533475
Nasher MA and Hay RJ Synergy of antibiotics against Streptomyces somaliensis isolates in vitro. 1998 J. Antimicrob. Chemother. pmid:9533473
Doucet-Populaire F et al. Molecular basis of clarithromycin activity against Mycobacterium avium and Mycobacterium smegmatis. 1998 J. Antimicrob. Chemother. pmid:9533459