| MeSH term | MeSH ID | Detail |
|---|---|---|
| Drug-Related Side Effects and Adverse Reactions | D064420 | 3 associated lipids |
| Vagus Nerve Injuries | D061223 | 1 associated lipids |
| Occupational Injuries | D060051 | 1 associated lipids |
| Acute Kidney Injury | D058186 | 34 associated lipids |
| Chemical and Drug Induced Liver Injury | D056486 | 39 associated lipids |
| Acute Lung Injury | D055371 | 33 associated lipids |
| Atrioventricular Block | D054537 | 1 associated lipids |
| Pneumonia, Ventilator-Associated | D053717 | 1 associated lipids |
| Kidney Diseases, Cystic | D052177 | 3 associated lipids |
| Granulomatosis, Orofacial | D051261 | 2 associated lipids |
erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- J. Pharmacol. Exp. Ther. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Cho T et al. | [Effects of EM on the intracellular Ca 2+ response in A549 cells]. | 2000 | Jpn J Antibiot | pmid:10756443 |
| Nakamura A et al. | [Selective suppression of aminoglycoside 3'-phosphorylating enzyme activities by macrolides--a study by using macrolide-resistant bacteria]. | 2000 | Jpn J Antibiot | pmid:10756446 |
| Homa K et al. | [Erythromycin sensitivity of Shigella flexneri and S. sonnei]. | 2000 | Jpn J Antibiot | pmid:10756447 |
| Sakamoto M et al. | [Usefulness of clarithromycin in paitents with unresectable non-small-cell lung cancer--clinical evaluation of those who survived for a long time and those succumbed in a short period]. | 2000 | Jpn J Antibiot | pmid:10756453 |
| Miyazawa T and Iino Y | [Effect of macrolides on ligand expression by T lymphocytes obtained from human peripheral blood]. | 2000 | Jpn J Antibiot | pmid:10756457 |
| Enomoto F et al. | [Involvement of adhesion molecules in experimental otitis media in rats--an in vitro evaluation]. | 2000 | Jpn J Antibiot | pmid:10756459 |
| Obori M et al. | [Effects of 14-member cyclic macrolide compounds on rat leukocyte chemotaxis]. | 2000 | Jpn J Antibiot | pmid:10756460 |
| Takahashi T et al. | [Efficacy of erythromycin (EM) on a rabbit model of Pseudomonas aeruginosa-induced chronic bronchiolitis--its action on apoptosis]. | 2000 | Jpn J Antibiot | pmid:10756461 |
| Dezaki S et al. | [Effects of macrolides on several transcription factors]. | 2000 | Jpn J Antibiot | pmid:10756462 |
| Komiyane M and Tamaoki K | [Clinical effects of macrolides on psoriasis vulgaris]. | 2000 | Jpn J Antibiot | pmid:10756468 |
| Cojocaru I et al. | [Dermatologic preparations with erythromycin--the correlation of the pharmaceutical form-therapeutic effect]. | 1997 Jul-Dec | Rev Med Chir Soc Med Nat Iasi | pmid:10756791 |
| Fowler SM et al. | Amino acid 305 determines catalytic center accessibility in CYP3A4. | 2000 | Biochemistry | pmid:10757990 |
| Curran JB et al. | Infection of abnormal heart valves and total joint prosthesis following dental procedures. | 1976 Jul-Aug | Northwest Dent | pmid:1075923 |
| Van Herwaarden MA et al. | The effect of motilin agonist ABT-229 on gastro-oesophageal reflux, oesophageal motility and lower oesophageal sphincter characteristics in GERD patients. | 2000 | Aliment. Pharmacol. Ther. | pmid:10759625 |
| Douthwaite S et al. | Macrolide-ketolide inhibition of MLS-resistant ribosomes is improved by alternative drug interaction with domain II of 23S rRNA. | 2000 | Mol. Microbiol. | pmid:10760175 |
| Miller P et al. | Neural and muscular receptors for motilin in the rabbit colon. | 2000 | Peptides | pmid:10764957 |
| Evans AJ and Krentz AJ | Should cisapride be avoided in patients with diabetic gastroparesis? | 1999 Sep-Dec | J. Diabetes Complicat. | pmid:10765008 |
| Osterholm MT | Erythromycin remains gold standard for treatment of pertussis in infants. | 2000 | Clin. Infect. Dis. | pmid:10766495 |
| Quirós LM et al. | Glycosylation of macrolide antibiotics. Purification and kinetic studies of a macrolide glycosyltransferase from Streptomyces antibioticus. | 2000 | J. Biol. Chem. | pmid:10766792 |
| Suwa M et al. | Identification of two polyketide synthase gene clusters on the linear plasmid pSLA2-L in Streptomyces rochei. | 2000 | Gene | pmid:10767533 |