erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Drug-Related Side Effects and Adverse Reactions D064420 3 associated lipids
Vagus Nerve Injuries D061223 1 associated lipids
Occupational Injuries D060051 1 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Chemical and Drug Induced Liver Injury D056486 39 associated lipids
Acute Lung Injury D055371 33 associated lipids
Atrioventricular Block D054537 1 associated lipids
Pneumonia, Ventilator-Associated D053717 1 associated lipids
Kidney Diseases, Cystic D052177 3 associated lipids
Granulomatosis, Orofacial D051261 2 associated lipids
Seroma D049291 2 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Pyloric Stenosis, Hypertrophic D046248 2 associated lipids
Moraxellaceae Infections D045828 3 associated lipids
Desulfovibrionaceae Infections D045824 5 associated lipids
Ileus D045823 3 associated lipids
Acalculous Cholecystitis D042101 3 associated lipids
Pelvic Infection D034161 1 associated lipids
Communicable Diseases, Emerging D021821 3 associated lipids
Neuroaspergillosis D020953 2 associated lipids
Epidural Abscess D020802 1 associated lipids
Enterocolitis, Necrotizing D020345 3 associated lipids
Postoperative Nausea and Vomiting D020250 1 associated lipids
Dermatitis, Perioral D019557 4 associated lipids
Postoperative Hemorrhage D019106 7 associated lipids
Sepsis D018805 11 associated lipids
Abdominal Abscess D018784 2 associated lipids
Arthralgia D018771 8 associated lipids
Gastroparesis D018589 2 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Lymphoma, B-Cell, Marginal Zone D018442 1 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Adrenocortical Carcinoma D018268 4 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
Limb Deformities, Congenital D017880 4 associated lipids
Granuloma, Pyogenic D017789 2 associated lipids
Community-Acquired Infections D017714 8 associated lipids
Retropharyngeal Abscess D017703 2 associated lipids
Lung Diseases, Interstitial D017563 5 associated lipids
Pityriasis Rosea D017515 3 associated lipids
Pityriasis Lichenoides D017514 2 associated lipids
Acneiform Eruptions D017486 3 associated lipids
Skin Diseases, Vascular D017445 1 associated lipids
Skin Diseases, Papulosquamous D017444 2 associated lipids
Gastric Outlet Obstruction D017219 1 associated lipids
Skin Diseases, Viral D017193 2 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Tachycardia, Ventricular D017180 9 associated lipids
AIDS-Related Opportunistic Infections D017088 9 associated lipids
Chalazion D017043 1 associated lipids
Angiomatosis, Bacillary D016917 2 associated lipids
Gram-Negative Bacterial Infections D016905 16 associated lipids
Ehrlichiosis D016873 2 associated lipids
Neisseriaceae Infections D016870 3 associated lipids
Ureaplasma Infections D016869 5 associated lipids
Death, Sudden, Cardiac D016757 12 associated lipids
Empyema, Pleural D016724 2 associated lipids
Critical Illness D016638 13 associated lipids
Vaginosis, Bacterial D016585 10 associated lipids
Purpura, Thrombocytopenic, Idiopathic D016553 4 associated lipids
Bronchial Hyperreactivity D016535 15 associated lipids
Foot Ulcer D016523 4 associated lipids
Bacteremia D016470 9 associated lipids
Prosthesis-Related Infections D016459 7 associated lipids
Torsades de Pointes D016171 2 associated lipids
Pleural Effusion, Malignant D016066 6 associated lipids
Eye Infections, Parasitic D015822 2 associated lipids
Erythema Chronicum Migrans D015787 3 associated lipids
Granuloma, Respiratory Tract D015769 1 associated lipids
Ethmoid Sinusitis D015521 2 associated lipids
Weight Gain D015430 101 associated lipids
Scleritis D015423 3 associated lipids
Mycobacterium avium-intracellulare Infection D015270 4 associated lipids
Sexually Transmitted Diseases, Bacterial D015231 5 associated lipids
Superinfection D015163 3 associated lipids
Yaws D015001 4 associated lipids
Xerostomia D014987 6 associated lipids
Wounds, Gunshot D014948 2 associated lipids
Wound Infection D014946 12 associated lipids
Whooping Cough D014917 6 associated lipids
Vulvovaginitis D014848 2 associated lipids
Vomiting D014839 21 associated lipids
Vibrio Infections D014735 5 associated lipids
Varicose Ulcer D014647 4 associated lipids
Uveitis D014605 14 associated lipids
Urticaria D014581 13 associated lipids
Urinary Tract Infections D014552 11 associated lipids
Urethritis D014526 9 associated lipids
Urethral Diseases D014522 4 associated lipids
Uremia D014511 33 associated lipids
Typhus, Epidemic Louse-Borne D014438 1 associated lipids
Typhus, Endemic Flea-Borne D014437 3 associated lipids
Tuberculosis, Pulmonary D014397 18 associated lipids
Tuberculosis D014376 20 associated lipids
Trisomy D014314 6 associated lipids
Trench Fever D014205 1 associated lipids
Tremor D014202 15 associated lipids
Toxoplasmosis, Animal D014124 5 associated lipids
Toothache D014098 3 associated lipids
Tooth, Impacted D014095 9 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Weber JM et al. An erythromycin process improvement using the diethyl methylmalonate-responsive (Dmr) phenotype of the Saccharopolyspora erythraea mutB strain. 2012 Appl. Microbiol. Biotechnol. pmid:22048617
Moncrieffe MC et al. Structure of the glycosyltransferase EryCIII in complex with its activating P450 homologue EryCII. 2012 J. Mol. Biol. pmid:22056329
Shimada M et al. Corneal ulcer associated with pepper spray exposure during military training. 2012 J Emerg Med pmid:22100497
Popowska M et al. Influence of soil use on prevalence of tetracycline, streptomycin, and erythromycin resistance and associated resistance genes. 2012 Antimicrob. Agents Chemother. pmid:22203596
Chouchani C et al. First report of mefA and msrA/msrB multidrug efflux pumps associated with blaTEM-1 β-lactamase in Enterococcus faecalis. 2012 Int. J. Infect. Dis. pmid:22137270
McCusker KP and Fujimori DG The chemistry of peptidyltransferase center-targeted antibiotics: enzymatic resistance and approaches to countering resistance. 2012 ACS Chem. Biol. pmid:22208312
Ducrotté P and Gourcerol G [Gastroparesis: pathophysiology and management]. 2012 Presse Med pmid:22154929
Back EE et al. High rates of perinatal group B Streptococcus clindamycin and erythromycin resistance in an upstate New York hospital. 2012 Antimicrob. Agents Chemother. pmid:22143529
Biester EM et al. Identification of avian wax synthases. 2012 BMC Biochem. pmid:22305293
Shiu WK et al. Antibacterial acylphloroglucinols from Hypericum olympicum. 2012 J. Nat. Prod. pmid:21899267
Gokmen T et al. A controlled trial of erythromycin and UDCA in premature infants during parenteral nutrition in minimizing feeding intolerance and liver function abnormalities. 2012 J Perinatol pmid:21566568
Boswihi SS et al. Serotypes and antibiotic resistance in Group B streptococcus isolated from patients at the Maternity Hospital, Kuwait. 2012 J. Med. Microbiol. pmid:21903822
Sadeghi SJ et al. Drug-drug interactions and cooperative effects detected in electrochemically driven human cytochrome P450 3A4. 2012 Bioelectrochemistry pmid:22480862
Nunoi H et al. A relationship between motilin and growth hormone secretagogue receptors. 2012 Regul. Pept. pmid:22465164
Jada S et al. Design and synthesis of novel magnolol derivatives as potential antimicrobial and antiproliferative compounds. 2012 Eur J Med Chem pmid:22424614
Saxena S et al. Practical disk diffusion method for detection of inducible clindamycin resistance in Staphylococcus aureus at a tertiary care hospital: implications for clinical therapy. 2012 J Commun Dis pmid:25151754
Yiannakopoulou E et al. Pharmacological modulation of oxidative stress response in minimally invasive surgery: systematic review. 2012 Surg Laparosc Endosc Percutan Tech pmid:22678313
Bai J et al. Erythromycin enhances CD4+Foxp3+ regulatory T-cell responses in a rat model of smoke-induced lung inflammation. 2012 Mediators Inflamm. pmid:22701274
Vázquez-Sánchez D et al. Incidence and characterization of Staphylococcus aureus in fishery products marketed in Galicia (Northwest Spain). 2012 Int. J. Food Microbiol. pmid:22704064
Correa AM et al. [Pneumococcal bacteremia in adult patients at a hospital in Madrid: serotypes and susceptibility]. 2012 Rev Esp Quimioter pmid:22707105
Teodoro CR et al. Characterization of MLS(b) resistance among Staphylococcus aureus and Staphylococcus epidermidis isolates carrying different SCCmec types. 2012 Microbiol. Immunol. pmid:22672011
Feng Z et al. Unidirectional peristaltic movement in multisite drug binding pockets of AcrB from molecular dynamics simulations. 2012 Mol Biosyst pmid:22825052
Maeda Y et al. UV-C-irradiation sublethal stress does not alter antibiotic susceptibility of the viridans group streptococci to β-lactam, macrolide, and fluoroquinolone antibiotic agents. 2012 J Investig Clin Dent pmid:22887906
Hossein nia R et al. An expeditious regioselective synthesis of novel bioactive indole-substituted chromene derivatives via one-pot three-component reaction. 2012 Bioorg. Med. Chem. Lett. pmid:22892120
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Aiello A et al. Aplisulfamines, new sulfoxide-containing metabolites from an aplidium tunicate: absolute stereochemistry at chiral sulfur and carbon atoms assigned through an original combination of spectroscopic and computational methods. 2012 Mar Drugs pmid:22363220
Molnari JC and Myers AL Carbonyl reduction of bupropion in human liver. 2012 Xenobiotica pmid:22339467
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Zhou X et al. Marthiapeptide A, an anti-infective and cytotoxic polythiazole cyclopeptide from a 60 L scale fermentation of the deep sea-derived Marinactinospora thermotolerans SCSIO 00652. 2012 J. Nat. Prod. pmid:23215246
Noto MJ and Wheeler AP Macrolides for acute lung injury. 2012 Chest pmid:22553255
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Kelley C et al. 3-Phenyl substituted 6,7-dimethoxyisoquinoline derivatives as FtsZ-targeting antibacterial agents. 2012 Bioorg. Med. Chem. pmid:23127490
Parhi A et al. Antibacterial activity of substituted 5-methylbenzo[c]phenanthridinium derivatives. 2012 Bioorg. Med. Chem. Lett. pmid:23084900
Benet LZ A step closer to personalized chemotherapy: consideration of the influence of genetic variation in hepatic uptake transporters on the metabolism of CYP3A substrates. 2012 Clin. Pharmacol. Ther. pmid:23085879
Laine L and Jensen DM Management of patients with ulcer bleeding. 2012 Am. J. Gastroenterol. pmid:22310222
Waseem S et al. Spectrum of gastroparesis in children. 2012 J. Pediatr. Gastroenterol. Nutr. pmid:22314391
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Zhou Q et al. SigB-dependent tolerance to protein synthesis-inhibiting antibiotics in Listeria monocytogenes EGDe. 2012 Curr. Microbiol. pmid:22143398
Zhang H et al. Improved E. coli erythromycin A production through the application of metabolic and bioprocess engineering. 2012 Jan-Feb Biotechnol. Prog. pmid:21905273
Pehr K Mycophenolate mofetil and erythromycin for bullous lupus erythematosus of childhood. 2012 Jan-Feb J Cutan Med Surg pmid:22417996
Amatya A et al. Comparative study of effectiveness of oral acyclovir with oral erythromycin in the treatment of Pityriasis rosea. 2012 Jan-Mar Kathmandu Univ Med J (KUMJ) pmid:22971864
Kuhn M et al. Feed restriction enhances the depressive effects of erythromycin on equine hindgut microbial metabolism in vitro. 2012 Jul-Aug Berl. Munch. Tierarztl. Wochenschr. pmid:22919930
Jiang RS et al. Efficacy of Chinese herbal medicine compared with a macrolide in the treatment of chronic rhinosinusitis without nasal polyps. 2012 Jul-Aug Am J Rhinol Allergy pmid:22801017
Kuehne SA and Minton NP ClosTron-mediated engineering of Clostridium. 2012 Jul-Aug Bioengineered pmid:22750794
Miguel AI et al. Pediatric ocular rosacea: 2 cases. 2012 Jul-Aug Eur J Ophthalmol pmid:22267454
Clementson B and Smidt AC Periorificial dermatitis due to systemic corticosteroids in children: report of two cases. 2012 May-Jun Pediatr Dermatol pmid:22122785
Hapa A et al. Childhood pityriasis lichenoides and oral erythromycin. 2012 Nov-Dec Pediatr Dermatol pmid:22639857
Asai N et al. A successfully treated case of parainfluenza virus 3 pneumonia mimicking influenza pneumonia. 2012 Nov-Dec J Bras Pneumol pmid:23288130
Lian W et al. Electrochemical sensor based on gold nanoparticles fabricated molecularly imprinted polymer film at chitosan-platinum nanoparticles/graphene-gold nanoparticles double nanocomposites modified electrode for detection of erythromycin. 2012 Oct-Dec Biosens Bioelectron pmid:22683249
Heelan K et al. Panton-Valentine leukocidin-producing Staphylococcal aureus: report of four siblings. 2012 Sep-Oct Pediatr Dermatol pmid:21906149
Jiang M and Pfeifer BA Metabolic and pathway engineering to influence native and altered erythromycin production through E. coli. 2013 Metab. Eng. pmid:23747605
Xia Q et al. Adaptive mechanisms of Campylobacter jejuni to erythromycin treatment. 2013 BMC Microbiol. pmid:23767761
Guan Y et al. [Effect of combination of sub-MIC sodium houttuyfonate and erythromycin on biofilm of Staphylococcus epidermidis]. 2013 Zhongguo Zhong Yao Za Zhi pmid:23724685
Lanzarotti C and Rossi G Effect of netupitant, a highly selective NK₁ receptor antagonist, on the pharmacokinetics of midazolam, erythromycin, and dexamethasone. 2013 Support Care Cancer pmid:23729226
Nemeghaire S et al. Characterization of methicillin-resistant Staphylococcus aureus from healthy carrier chickens. 2013 Avian Pathol. pmid:23777220
Patel AM et al. Statin toxicity from macrolide antibiotic coprescription: a population-based cohort study. 2013 Ann. Intern. Med. pmid:23778904
Wasels F et al. Clostridium difficile erm(B)-containing elements and the burden on the in vitro fitness. 2013 J. Med. Microbiol. pmid:23741023
Kawai Y et al. Nationwide surveillance of macrolide-resistant Mycoplasma pneumoniae infection in pediatric patients. 2013 Antimicrob. Agents Chemother. pmid:23716043
Guo L et al. Refining the human iPSC-cardiomyocyte arrhythmic risk assessment model. 2013 Toxicol. Sci. pmid:24052561
Guo MT et al. Ultraviolet reduction of erythromycin and tetracycline resistant heterotrophic bacteria and their resistance genes in municipal wastewater. 2013 Chemosphere pmid:24055024
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Jiang M et al. Deoxysugar pathway interchange for erythromycin analogues heterologously produced through Escherichia coli. 2013 Metab. Eng. pmid:24060454
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Kwak HM et al. The efficacy of cefazolin plus macrolide (erythromycin or clarithromycin) versus cefazolin alone in neonatal morbidity and placental inflammation for women with preterm premature rupture of membranes. 2013 Placenta pmid:23465535
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Magee TV et al. Novel 3-O-carbamoyl erythromycin A derivatives (carbamolides) with activity against resistant staphylococcal and streptococcal isolates. 2013 Bioorg. Med. Chem. Lett. pmid:23414806
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Broad J and Sanger GJ The antibiotic azithromycin is a motilin receptor agonist in human stomach: comparison with erythromycin. 2013 Br. J. Pharmacol. pmid:23190027
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Malinka W et al. Synthesis of novel isothiazolopyridines and their in vitro evaluation against Mycobacterium and Propionibacterium acnes. 2013 Bioorg. Med. Chem. pmid:23850103
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Yang X et al. Occurrence and fate of PPCPs and correlations with water quality parameters in urban riverine waters of the Pearl River Delta, South China. 2013 Environ Sci Pollut Res Int pmid:23608973
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Chang YC and Lo HH Identification, clinical aspects, susceptibility pattern, and molecular epidemiology of beta-haemolytic group G Streptococcus anginosus group isolates from central Taiwan. 2013 Diagn. Microbiol. Infect. Dis. pmid:23632249
Müller M et al. The absolute configuration of (+)- and (-)-erythro-mefloquine. 2013 Angew. Chem. Int. Ed. Engl. pmid:23616269
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Kjær S et al. Ultrasound-guided drainage of subcutaneous abscesses on the trunk is feasible. 2013 Dan Med J pmid:23651712
Fysal N et al. Antibiogram pattern of oral microflora in periodontic children of age group 6 to 12 years: a clinicomicrobiological study. 2013 J Contemp Dent Pract pmid:24309334
Li X et al. Synthesis and antibacterial evaluation of novel 11,4″-disubstituted azithromycin analogs with greatly improved activity against erythromycin-resistant bacteria. 2013 Eur J Med Chem pmid:23229056
Nunez-Samudio V and Chesneau O Functional interplay between the ATP binding cassette Msr(D) protein and the membrane facilitator superfamily Mef(E) transporter for macrolide resistance in Escherichia coli. 2013 Res. Microbiol. pmid:23261969
Secka O et al. Antimicrobial susceptibility and resistance patterns among Helicobacter pylori strains from The Gambia, West Africa. 2013 Antimicrob. Agents Chemother. pmid:23263004
Bruchmann J et al. Sub-inhibitory concentrations of antibiotics and wastewater influencing biofilm formation and gene expression of multi-resistant Pseudomonas aeruginosa wastewater isolates. 2013 Environ Sci Pollut Res Int pmid:23392972
Simoens S et al. Preventing COPD exacerbations with macrolides: a review and budget impact analysis. 2013 Respir Med pmid:23352223
Jiang M et al. The logic, experimental steps, and potential of heterologous natural product biosynthesis featuring the complex antibiotic erythromycin A produced through E. coli. 2013 J Vis Exp pmid:23354010
Elens L et al. CYP3A4 intron 6 C>T SNP (CYP3A4*22) encodes lower CYP3A4 activity in cancer patients, as measured with probes midazolam and erythromycin. 2013 Pharmacogenomics pmid:23327575
Cui B et al. Differences between two clinical Staphylococcus capitis subspecies as revealed by biofilm, antibiotic resistance, and pulsed-field gel electrophoresis profiling. 2013 J. Clin. Microbiol. pmid:23052315