erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Camilleri M and Prather CM | Axial forces during gastric emptying in health and models of disease. | 1994 | Dig. Dis. Sci. | pmid:7995207 |
Peeters TL and Depoortere I | Motilin receptor: a model for development of prokinetics. | 1994 | Dig. Dis. Sci. | pmid:7995222 |
Maeda K et al. | [Suppression of the Pseudomonas aeruginosa-induced biofilm formation on human epithelial cells by erythromycin]. | 1994 | Kansenshogaku Zasshi | pmid:7996019 |
Torabinejad M et al. | Effectiveness of various medications on postoperative pain following complete instrumentation. | 1994 | J Endod | pmid:7996097 |
Torabinejad M et al. | Effectiveness of various medications on postoperative pain following root canal obturation. | 1994 | J Endod | pmid:7996111 |
From the Centers for Disease Control and Prevention. Erythromycin-resistant Bordetella pertussis--Yuma County, Arizona, May-October 1994. | 1995 | JAMA | pmid:7996637 | |
Mani C et al. | Involvement of cytochrome P4503A in catalysis of tamoxifen activation and covalent binding to rat and human liver microsomes. | 1994 | Carcinogenesis | pmid:8001226 |
Sørensen JL et al. | Early- and late-onset pelvic inflammatory disease among women with cervical Chlamydia trachomatis infection at the time of induced abortion--a follow-up study. | 1994 Jul-Aug | Infection | pmid:8002083 |
Bush MR and Rosa C | Azithromycin and erythromycin in the treatment of cervical chlamydial infection during pregnancy. | 1994 | Obstet Gynecol | pmid:8008325 |
Pajukanta R et al. | Evaluation of the E test for antimicrobial susceptibility testing of Porphyromonas gingivalis. | 1994 | Oral Microbiol. Immunol. | pmid:8008429 |
MacNeil DJ et al. | Correlation of the avermectin polyketide synthase genes to the avermectin structure. Implications for designing novel avermectins. | 1994 | Ann. N. Y. Acad. Sci. | pmid:8010663 |
Klugman KP et al. | Cluster of an erythromycin-resistant variant of the Spanish multiply resistant 23F clone of Streptococcus pneumoniae in South Africa. | 1994 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:8013492 |
Broadway DC et al. | Mycobacterium chelonei keratitis: a case report and review of previously reported cases. | 1994 | Eye (Lond) | pmid:8013708 |
Nishijima S et al. | The antibiotic susceptibility of Propionibacterium acnes and Staphylococcus epidermidis isolated from acne. | 1994 | J. Dermatol. | pmid:8014270 |
Dorrell L et al. | Intravenous azithromycin as salvage therapy in a patient with Legionnaire's disease. | 1994 | Thorax | pmid:8016806 |
Turgeon DK et al. | Prediction of interpatient and intrapatient variation in OG 37-325 dosing requirements by the erythromycin breath test. A prospective study in renal transplant recipients. | 1994 | Transplantation | pmid:8016878 |
Farrar HC et al. | Cardiac toxicity associated with intravenous erythromycin lactobionate: two case reports and a review of the literature. | 1993 | Pediatr. Infect. Dis. J. | pmid:8018130 |
Kounenis G et al. | Comparative study of erythromycin, troleandomycin and tylosin on the rabbit intestine. | 1994 | Fundam Clin Pharmacol | pmid:8020874 |
Mehta A et al. | Antibiotic inhibition of pectolytic and cellulolytic enzyme activity in two Fusarium species. | 1993 | Mycopathologia | pmid:8022465 |
Zechnich AD et al. | Possible interactions with terfenadine or astemizole. | 1994 | West. J. Med. | pmid:8023479 |
Winkler M et al. | [Puerperium after threatened premature labor--effects of infection screening in pregnancy]. | 1994 Mar-Apr | Z Geburtshilfe Perinatol | pmid:8023535 |
Di Lorenzo C et al. | Effect of erythromycin on antroduodenal motility in children with chronic functional gastrointestinal symptoms. | 1994 | Dig. Dis. Sci. | pmid:8026249 |
Koutsoviti-Papadopoulou M et al. | Effect of erythromycin on different parts of the rabbit intestine: comparison with motilin. | 1994 | Gen. Pharmacol. | pmid:8026719 |
Gostishchev VK et al. | [Diagnosis and surgical treatment of foot osteomyelitis]. | 1994 | Khirurgiia (Mosk) | pmid:8028247 |
Stella PR et al. | Systemic infection with Nocardia asteroides cured with amoxicillin/clavulanic acid, erythromycin and ultrasound-guided transcutaneous aspiration. | 1994 | Neth J Med | pmid:8028693 |
Ishida K et al. | In vitro and in vivo activities of macrolides against Mycoplasma pneumoniae. | 1994 | Antimicrob. Agents Chemother. | pmid:8031048 |
Carlin EM et al. | Group A beta haemolytic streptococcal proctitis in an HIV-positive man. | 1994 Mar-Apr | Int J STD AIDS | pmid:8031920 |
Liippo K et al. | A comparative study of dirithromycin and erythromycin in bacterial pneumonia. | 1994 | J. Infect. | pmid:8034992 |
Parkinson AJ et al. | Serotype distribution and antimicrobial resistance patterns of invasive isolates of Streptococcus pneumoniae: Alaska 1986-1990. | 1994 | J. Infect. Dis. | pmid:8035038 |
Della Santa L et al. | [Pulmonary infections in children. I -- pneumonia due to Legionella pneumophila]. | 1994 | Minerva Pediatr. | pmid:8035763 |
Waites KB et al. | Serum concentrations of erythromycin after intravenous infusion in preterm neonates treated for Ureaplasma urealyticum infection. | 1994 | Pediatr. Infect. Dis. J. | pmid:8036045 |
Kao CM et al. | Engineered biosynthesis of a complete macrolactone in a heterologous host. | 1994 | Science | pmid:8036492 |
Yasbin RE et al. | Transformation and transfection in lysogenic strains of Bacillus subtilis: evidence for selective induction of prophage in competent cells. | 1975 | J. Bacteriol. | pmid:803952 |
Mtairag EM et al. | Investigation of dirithromycin and erythromycylamine uptake by human neutrophils in vitro. | 1994 | J. Antimicrob. Chemother. | pmid:8040116 |
Dillon HC and Derrick CW | Clinical experience with clindamycin hydrochloride: I. Treatment of streptococcal and mixed streptococcal-staphylococcal skin infections. | 1975 | Pediatrics | pmid:804159 |
Yeary RA | Systemic toxic effects of chemotherapeutic agents in domestic animals. | 1975 | Vet Clin North Am | pmid:804202 |
Ates S et al. | In vitro release of erythromycin from hydrogels. | 1994 | Pharmazie | pmid:8047550 |
Rezkalla MA and Pochop C | Erythromycin induced Torsades de Pointes: case report and review of the literature. | 1994 | S D J Med | pmid:8047870 |
Sadrieh N and Thomas PE | Characterization of rat cytochrome P450 isozymes involved in the covalent binding of cyclosporin A to microsomal proteins. | 1994 | Toxicol. Appl. Pharmacol. | pmid:8048065 |
Iino Y et al. | [Histopathological studies on paranasal mucosa from patients treated with erythromycin]. | 1994 | Nippon Jibiinkoka Gakkai Kaiho | pmid:8051596 |
Matsunaga T et al. | [On the antimicrobial activities of oral cephems against methicillin-sensitive Staphylococcus aureus isolated from children with pediatric infection]. | 1994 | Jpn J Antibiot | pmid:8051791 |
Ooshima T et al. | Detection of caries-inducing microorganisms in hyposalivated rats without infection of mutans streptococci. | 1994 | Microbiol. Immunol. | pmid:8052161 |
Lee WR et al. | Bacillary angiomatosis of the conjunctiva. | 1994 | Am. J. Ophthalmol. | pmid:8053460 |
Durack DT | Current practice in prevention of bacterial endocarditis. | 1975 | Br Heart J | pmid:805596 |
Wood GD and Deeble T | Warfarin: dangers with antibiotics. | 1993 | Dent Update | pmid:8056109 |
Wynn RL | Dental drug interactions with the greatest potential for serious adverse effects. | 1994 Mar-Apr | Gen Dent | pmid:8056271 |
Tanaka E et al. | The effect of erythromycin on Pseudomonas aeruginosa and neutrophil mediated epithelial damage. | 1994 | J. Antimicrob. Chemother. | pmid:8056695 |
Bonacorsi S and Bingen E | Bactericidal activity of erythromycin associated with sulphisoxazole against the infectious agents most frequently responsible for acute infantile otitis media. | 1994 | J. Antimicrob. Chemother. | pmid:8056713 |
Treatment of acute otitis media. | 1975 | Med Lett Drugs Ther | pmid:805905 | |
StrachunskiÄ LS et al. | [Comparative clinical effectiveness and tolerance of azithromycin (sumamed) and erythromycin in patients with sinusitis]. | 1993 | Antibiot. Khimioter. | pmid:8060176 |
Shubin SV et al. | [Effectiveness of azithromycin relative to chlamydia infection in reactive arthritis]. | 1993 | Antibiot. Khimioter. | pmid:8060177 |
Kirichenko NV et al. | [Isolation and characterization of genetic recombinants in protoplast fusion in Saccharopolyspora erythraea]. | 1993 | Antibiot. Khimioter. | pmid:8060179 |
Miller LW | Letter: diphtheria carriers. | 1975 | Ann. Intern. Med. | pmid:806244 |
Perry TL | Antibiotic abuse: the testimony of medical students. | 1975 | Can Med Assoc J | pmid:806341 |
Fargette F and Grelet N | [Bacillus thuringiensis Berliner mutants resistant to various antibiotics and showing alterations of sporulation]. | 1975 | C.R. Hebd. Seances Acad. Sci., Ser. D, Sci. Nat. | pmid:806389 |
ElTabbakh GH et al. | Primary syphilis and nonimmune fetal hydrops in a penicillin-allergic woman. A case report. | 1994 | J Reprod Med | pmid:8064710 |
Fujiwara H et al. | [Pure red cell aplasia induced by erythromycin and furosemide effects on in vitro erythroid colony forming unit (CFU-E)]. | 1994 | Rinsho Ketsueki | pmid:8065024 |
Bremmelgaard A et al. | Evaluation of the E-test for susceptibility testing of the Bacteroides fragilis group. Danish study group. | 1994 | APMIS | pmid:8068304 |
MatkovskiÄ VS and Liashenko IuI | [Basic principles of antistreptococcal treatment of angina]. | 1975 | Sov Med | pmid:806973 |
Kawashima Y et al. | Structure-activity relationship study of 6-O-methylerythromycin 9-O-substituted oxime derivatives. | 1994 | Chem. Pharm. Bull. | pmid:8069961 |
van der Sande FM and Hoorntje SJ | Acute interstitial nephritis with septicemia and erythromycin. | 1994 | Nephron | pmid:8072620 |
Sterne GG | Group A beta-hemolytic streptococci and erythromycin. | 1994 | Arch Pediatr Adolesc Med | pmid:8075755 |
Flurer CL and Wolnik KA | Chemical profiling of pharmaceuticals by capillary electrophoresis in the determination of drug origin. | 1994 | J Chromatogr A | pmid:8075768 |
Patel SP and Jarowski CI | Oral absorption efficiency of acid-labile antibiotics from lipid-drug delivery systems. | 1975 | J Pharm Sci | pmid:807706 |
Peterman TA et al. | Incubating syphilis in patients treated for gonorrhea: a comparison of treatment regimens. | 1994 | J. Infect. Dis. | pmid:8077730 |
Hortal M et al. | Antimicrobial resistance in Streptococcus pneumoniae strains from Uruguay. | 1994 | Pediatr. Infect. Dis. J. | pmid:8078746 |
Lartey PA et al. | New developments in macrolides: structures and antibacterial and prokinetic activities. | 1994 | Adv. Pharmacol. | pmid:8080820 |
Salgado F et al. | [Bacillary angiomatosis: report of 2 cases]. | 1994 Jun-Jul | Enferm. Infecc. Microbiol. Clin. | pmid:8080867 |
Yag Y et al. | Plasmid-determined resistance to erythromycin: comparison of strains of streptococcus faecalis and streptococcus pyogenes with regard to plasmid hmology and resistance inducibility. | 1975 | Antimicrob. Agents Chemother. | pmid:808161 |
Stewart JJ et al. | Effects of motion sickness and antimotion sickness drugs on gastric function. | 1994 | J Clin Pharmacol | pmid:8083395 |
Weber DJ and Rutala WA | Management of healthcare workers exposed to pertussis. | 1994 | Infect Control Hosp Epidemiol | pmid:8083507 |
Wanat FE and Wychulis AR | Diphtheroid endocarditis after aortic valve replacement. | 1975 | Chest | pmid:808399 |
Della Santa L et al. | [Pulmonary infections in children. II - Mycoplasma pneumonia]. | 1994 | Minerva Pediatr. | pmid:8084321 |
Weekes JW | Erythromycin to facilitate placement of naso-duodenal feeding tubes. | 1994 | Anaesth Intensive Care | pmid:8085646 |
Pozdniakova VP et al. | [Protegentin--a combined preparation for the local treatment of suppurative infection]. | 1993 Oct-Nov | Antibiot. Khimioter. | pmid:8085892 |
Relman DA | Bacillary angiomatosis and Rochalimaea species. | 1994 | Curr Clin Top Infect Dis | pmid:8086116 |
LeMahieu RA et al. | Aromatic esters of 5-O-desosaminylerythronolide A oxime. | 1975 | J. Med. Chem. | pmid:808612 |
Brandriss MW et al. | Erythromycin-induced QT prolongation and polymorphic ventricular tachycardia (torsades de pointes): case report and review. | 1994 | Clin. Infect. Dis. | pmid:8086567 |
Fernandez Redondo V et al. | Systemic contact dermatitis from erythromycin. | 1994 | Contact Derm. | pmid:8088157 |
Kaufman A et al. | Streptococcal sore throat followup program in a hospital clinic, New York City. | 1975 Jul-Aug | Public Health Rep | pmid:808824 |
Baughman RP et al. | The penetration of dirithromycin into bronchoalveolar lavage fluid and alveolar macrophages. | 1994 | J. Antimicrob. Chemother. | pmid:8089052 |
Della Santa L et al. | [Pulmonary infections in children. III. Pneumonia due to Chlamydia trachomatis]. | 1994 | Minerva Pediatr. | pmid:8090137 |
Della Santa L et al. | [Lung infections in children. IV. Pneumonia due to Chlamydia pneumoniae]. | 1994 | Minerva Pediatr. | pmid:8090147 |
Paradisi M et al. | [Perianal streptococcal dermatitis]. | 1994 | Minerva Pediatr. | pmid:8090151 |
Woods R | An assessment of antibiotics for the treatment of pyogenic dental infections. | 1975 | Aust Dent J | pmid:809025 |
Tarnow-Mordi W et al. | Randomized controlled trials of antibiotics in preterm labor. | 1994 | Am. J. Obstet. Gynecol. | pmid:8092243 |
Gully C and Riem R | [Torsades de pointes caused by the association of terfenadine and erythromycin]. | 1994 | Ann Med Interne (Paris) | pmid:8092653 |
Wynn RF et al. | Azithromycin for cerebral toxoplasmosis in AIDS. | 1993 | Lancet | pmid:8093526 |
Vantrappen G | Acute colonic pseudo-obstruction. | 1993 | Lancet | pmid:8093750 |
Qin XY et al. | Effects of cholinoceptor and 5-hydroxytryptamine3 receptor antagonism on erythromycin-induced canine intestinal motility disruption and emesis. | 1993 | Br. J. Pharmacol. | pmid:8094027 |
Ramirez B and Richter JE | Review article: promotility drugs in the treatment of gastro-oesophageal reflux disease. | 1993 | Aliment. Pharmacol. Ther. | pmid:8094981 |
Morgan MS and Cruickshank JG | Prevention of postsplenectomy sepsis. | 1993 | Lancet | pmid:8095614 |
Dirithromycin: a new once-daily macrolide. Symposium proceedings. Rome, 20-21 March 1992. | 1993 | J. Antimicrob. Chemother. | pmid:8097512 | |
Bailey RL et al. | Randomised controlled trial of single-dose azithromycin in treatment of trachoma. | 1993 | Lancet | pmid:8102427 |
Mikasa K et al. | [Effect of erythromycin on production of cytotoxin and attachment factors of bacteria]. | 1993 | Kansenshogaku Zasshi | pmid:8103071 |
Mukae H et al. | Elevation of tumor-associated carbohydrate antigens in patients with diffuse panbronchiolitis. | 1993 | Am. Rev. Respir. Dis. | pmid:8103656 |
Yeo CJ et al. | Erythromycin accelerates gastric emptying after pancreaticoduodenectomy. A prospective, randomized, placebo-controlled trial. | 1993 | Ann. Surg. | pmid:8103982 |
LeMahieu RA et al. | A novel intramolecular displacement reaction of 5-O-desosaminylerythronolide A oxime. | 1975 | J. Antibiot. | pmid:810470 |
Sparling PF et al. | Inheritance of low-level resistance to penicillin, tetracycline, and chloramphenicol in Neisseria gonorrhoeae. | 1975 | J. Bacteriol. | pmid:810479 |
Sarubbi FA et al. | Loss of low-level antibiotic resistance in Neisseria gonorrhoeae due to env mutations. | 1975 | J. Bacteriol. | pmid:810480 |