erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Cundliffe E and McQuillen K | Peptide bond formation: the effects of antibiotics on the puromycin reaction. | 1968 | J. Gen. Microbiol. | pmid:4968006 |
Cundliffe E and McQuillen K | Peptide-bond formation: the modes of action of chloramphenicol, sparsomycin and erythromycin. | 1968 | J. Gen. Microbiol. | pmid:4968007 |
Cerná J and RychlÃk I | Cross resistance of Escherichia coli B ribosomes to inhibition of the puromycin reaction by erythromycin, spiramycin and chloramphenicol. | 1968 | Biochim. Biophys. Acta | pmid:4870247 |
Shipley A et al. | T-strain mycoplasmas in non-specific urethritis. | 1968 | Med. J. Aust. | pmid:4872365 |
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Garanin BA | [Sensitivity toward antibiotics of Shigella Sonnei of individual fermentative types based on data from a hospital for communicable diseases during 1966]. | 1968 | Antibiotiki | pmid:4877060 |
Sanders E et al. | Group A beta-hemolytic streptococci resistant to erythromycin and lincomycin. | 1968 | N. Engl. J. Med. | pmid:4966066 |
Ross S | Erythromycin, oleandomycin and triacetyloleandomycin. | 1968 | Pediatr. Clin. North Am. | pmid:4867776 |
Mao JC and Putterman M | Accumulation in gram-postive and gram-negative bacteria as a mechanism of resistance to erythromycin. | 1968 | J. Bacteriol. | pmid:4966821 |
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Frisby BR | A laboratory comparison of tri-acetyl oleandomycin and nine other antibiotics. | 1968 | Med. J. Aust. | pmid:4967052 |
Lindsay AE and Truxal AC | Oral therapy in bacterial endocarditis. | 1968 | Rocky Mt Med J | pmid:4967211 |
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Choudhuri KK and Basu Mallick KC | Study of antibiotic-resistant staphylococci isolated from different sources and their role in pathogenicity. | 1968 | Indian J. Med. Res. | pmid:5186305 |
Robertson MH | Tetracycline-resistant streptococci in South-west Essex: a continuing survey. | 1968 | Br Med J | pmid:5186976 |
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Franco S et al. | Erythromycin in childhood pneumonias. | 1968 | Curr Ther Res Clin Exp | pmid:4969674 |
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Sabath LD et al. | Enhancing effect on alkalinization of the medium on the activity of erythromycin against gram-negative bacteria. | 1968 | Appl Microbiol | pmid:4970991 |
Jewett JF et al. | Childbed fever--a continuing entity. | 1968 | JAMA | pmid:4971028 |
Iats'ko VA | [On the dynamics of sensitivity to antibiotics of different microorganisms, isolated from patients of a surgical section]. | 1968 | Antibiotiki | pmid:4971186 |
Betinová M | [Effect of tetracyclines, macrolide antibiotics, and sigmamycin on staphylococci in vitro]. | 1968 | Biologia | pmid:4971503 |
Erythromycin compared with phenoxymethyl-penicillin and tetracycline. | 1968 | Practitioner | pmid:4972106 | |
Ahmed A | Altered ribosomes in spiramycin-resistant mutants of Bacillus subtilis. | 1968 | Biochim. Biophys. Acta | pmid:4972350 |
Gabraschanski P | [Gallimycin for therapy and prophylaxis of some diseases or the rock partridge in Bulgaria]. | 1968 | Dtsch Tierarztl Wochenschr | pmid:5693286 |
De Vries JA et al. | Adjunctive use of antibiotics in traumatic dental procedures. | 1968 | Int Z Klin Pharmakol Ther Toxikol | pmid:4972570 |
Fekety FR | Gastrointestinal complications of antibiotic therapy. | 1968 | JAMA | pmid:5694045 |
Jackson DM | The burnt child and his family. What the burnt child goes through. | 1968 | Proc. R. Soc. Med. | pmid:4972634 |
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Sabath LD et al. | Excretion of erythromycin and its enhanced activity in urine against gram-negative bacilli with alkalinization. | 1968 | J. Lab. Clin. Med. | pmid:4972710 |
Ramos e Silva J | [Current treatment of syphilis, particularly of early syphilis]. | 1968 | Rev Bras Med | pmid:5707186 |
Velluti G and Grifa P | [In vitro activity of erythromycin on various mycobacterium strains]. | 1968 | G Mal Infett Parassit | pmid:4976935 |
Hejzlar M et al. | Ten-year study of Neisseria gonorrhoeae sensitivity to antibiotics in Czechoslovakia. | 1968 | J Hyg Epidemiol Microbiol Immunol | pmid:4977454 |
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Magliulo E et al. | [Effects of a lysozyme-antibiotic combination on the phagocytic activity of human neutrophil granulocytes]. | 1968 | Arch Sci Med (Torino) | pmid:5733616 |
Weinstein MJ et al. | Preliminary studies on megalomicin, a new Micromonospora-produced macrolide antibiotic complex. | 1968 | Antimicrob Agents Chemother (Bethesda) | pmid:5735370 |
Paterson PY and Madden GM | Occurrence and erythromycin susceptibility of penicillin-resistant Viridans streptococci in rheumatic fever patients on oral penicillin prophylaxis. | 1968 | Antimicrob Agents Chemother (Bethesda) | pmid:5735376 |
McGehee RF R et al. | Resistance of Staphylococcus aureus to lincomycin, clinimycin, and erythromycin. | 1968 | Antimicrob Agents Chemother (Bethesda) | pmid:5735385 |
Wick WE and Mallett GE | New analysis for the therapeutic efficacy opropionyl erythromycin and erythromycin base. | 1968 | Antimicrob Agents Chemother (Bethesda) | pmid:5735386 |
Kuntsevich LD | [Erythromycin and oleandomycin in therapy of fresh gonorrhea in women]. | 1968 | Vestn Dermatol Venerol | pmid:5738081 |
Pezzìca R | [Damage caused by associated antibiotics in domiciliary therapy of acute febrile diseases. Film: "These 3 neutrophil leukocytes are from a 4-year-old child on the fourth day of treatment with CAF in average therapeutic doses. The toxic granulations in the protoplasm are clearly visible"]. | 1968 | Minerva Pediatr. | pmid:5739033 |
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Renzini G et al. | [Study of the antibacterial activity and of the serum and tissue levels produced in animals by the administration of two antibiotic associations]. | 1968 | Antibiotica | pmid:5740898 |
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Martini J et al. | [Treatment of acute male gonococcal urethritis with a single dosis of erythromycin-stearate]. | 1968 | Rev Med Chil | pmid:5746282 |
Mitsui Y and Suzuki H | [Evaluation of colistin-erythromycin ointment and solution in ophthalmology]. | 1968 | Nihon Ganka Kiyo | pmid:5748900 |
Pulverer G | [Studies with lysostaphin. I. Lysostaphin sensitivity of 355 strains of Staph. aureus of human origin]. | 1968 | Z Med Mikrobiol Immunol | pmid:5710870 |
Mao JC and Wiegand RG | Mode of action of macrolides. | 1968 | Biochim. Biophys. Acta | pmid:5649911 |
Puito L | [Antibiotic therapy in infancy]. | 1968 | Pediatria (Napoli) | pmid:4312284 |
Amato Neto V and Wanderley RA | [Use of an erythromycin stearate preparation, of regulated intestinal release in the treatment of intestinal amebiasis]. | 1968 | Hospital (Rio J) | pmid:5311770 |
Morgan IG and Austin L | Synaptosomal protein synthesis in a cell-free system. | 1968 | J. Neurochem. | pmid:4230127 |
Smith CC et al. | Bacterial substitution for staphylococcal infection. | 1968 | N. Z. Med. J. | pmid:4231513 |
Bülow P | A new epidemic phage type of Staphylococcus aureus. I. The experimental typing phage 6557'. | 1968 | Acta Pathol Microbiol Scand | pmid:4231992 |
Bülow P | A new epidemic phage type of Staphylococcus aureus. 2. Characteristics of staphylococci lysed by phage 6557'. | 1968 | Acta Pathol Microbiol Scand | pmid:4231993 |
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Beck LE | Some recent advances and trends in drug therapy. 2. Antibiotics. | 1968 | Med. J. Aust. | pmid:4233563 |
Jayaraman J and Goldberg IH | Localization of sparsomycin action to the peptide-bond-forming step. | 1968 | Biochemistry | pmid:4921281 |
Herrschaft H | [On the participation of the central nervous system in Behcet's disease]. | 1968 | Dtsch. Med. Wochenschr. | pmid:5655850 |
Ezekiel DH and Elkins BN | The stimulation of ribonucleic acid synthesis by ribosome inhibitors in amino acid-starved Escherichia coli. | 1968 | Biochim. Biophys. Acta | pmid:4234520 |
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Wyman JB et al. | Pancreatic, hepatic, and renal excretion of antibiotics in dogs. Observations on erythromycin, lincomycin, kanamycin, and colistimethate excretion. | 1968 | Arch Surg | pmid:5657416 |
Hashimoto H et al. | Drug resistance of staphylococci. IX. Inducible resistance to macrolide antibiotics in Staphylococcus aureus. | 1968 | Jpn. J. Microbiol. | pmid:4236812 |
Schmitt BD | Indications for tetracycline in pediatrics. | 1968 | Pediatrics | pmid:5657689 |
Forshaw J | Penicillin-induced granulopenia. | 1968 | Br Med J | pmid:5662555 |
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Mezey E et al. | Serum alcohol dehydrogenase, an indicator of intrahepatic cholestasis. | 1968 | N. Engl. J. Med. | pmid:5662777 |
The macrolides and lincomycin. | 1968 | Br Med J | pmid:5662980 | |
Sanders S and Norman AP | The bacterial flora of the upper respiratory tract in children with severe asthma. | 1968 | J Allergy | pmid:5300899 |
McGehee RF et al. | Comparative studies of antibacterial activity in vitro and absorption and excretion of lincomycin and clinimycin. | 1968 | Am. J. Med. Sci. | pmid:4386950 |
Oppenheimer S and Turek M | Laboratory and clinical evaluation of 7-chloro-7-deoxylincomycin. | 1968 | Am. J. Med. Sci. | pmid:4386951 |
Noonan JA et al. | Cerebral and cardiac complications from bacterial endocarditis. A successfully managed case with unusual complications. | 1968 | Am. J. Dis. Child. | pmid:5303294 |
Gause GG and Grünberger D | Translational characteristics of ribosomes and coding properties of transfer RNA in the mutant of bacterium paracoli with the increased GC content of DNA. | 1968 | Biochim. Biophys. Acta | pmid:5680608 |
Dixon JM | Group A Streptococcus resistant to erythromycin and lincomycin. | 1968 | Can Med Assoc J | pmid:4386993 |
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Wayland LG and Weiss PJ | Identification of antibiotics in sensitivity disks. | 1968 | J Pharm Sci | pmid:4173079 |
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Winningham DG et al. | Diffusion of antibiotics from plasma into prostatic fluid. | 1968 | Nature | pmid:4298194 |
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MacLowry JD and Marsh HH | Semiautomatic microtechnique for serial dilution-antibiotic sensitivity testing in the clinical laboratory. | 1968 | J. Lab. Clin. Med. | pmid:4175675 |
Vasarinsh P | Primary cutaneous nocardiosis. | 1968 | Arch Dermatol | pmid:5684220 |
Tereshin IM and Belousova II | [Effect of some antibiotics on the transfer of the resistance to tetracycline and chloramphenicol by means of the episome factor (Rtf)]. | 1968 | Antibiotiki | pmid:4298603 |
Sabath LD et al. | Serum glutamic oxalacetic transaminase. False elevations during administration of erythromycin. | 1968 | N. Engl. J. Med. | pmid:5686481 |
Rajka G | Treatment of gonorrhoea patients with intolerance to penicillin. | 1968 | Acta Derm. Venereol. | pmid:4177580 |
Grimble AS | Possible Mycoplasma hominis urethritis rvealed by differing responses of "abacterial urethritis" to treatment with tetracycline and erythromycin. | 1968 | Br J Vener Dis | pmid:5687045 |
Weisblum B and Davies J | Antibiotic inhibitors of the bacterial ribosome. | 1968 | Bacteriol Rev | pmid:4179192 |
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Ivanitskaia LP and Manafova NA | [Study of sensitivity to antibiotics in cultures of Anacystis nidulans and Chlorella sp. in relation to their possible use as tests in selection of new biologically active compounds from Actinomycetes]. | 1968 | Antibiotiki | pmid:4180805 |
Hirasawa K | [Studies on renin-angiotensin system. I. Angiotensinase activities in hepatic disorders]. | 1968 | Jpn. Circ. J. | pmid:4299837 |
Barnes RW et al. | Studies of sterility of calf venous blood. | 1968 | Surgery | pmid:4300855 |
Dohlman CH and Boruchoff SA | Penetrating keratoplasty. | 1968 | Int Ophthalmol Clin | pmid:4904228 |
Ruczaj Z | Sensitivity of microorganisms to antibiotics produced by them. | 1968 | Arch. Immunol. Ther. Exp. (Warsz.) | pmid:4302938 |
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Minkova GL | [On the sensitivity of microflora of burn wounds to antibiotics]. | 1968 | Antibiotiki | pmid:4305269 |