erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- J. Pharmacol. Exp. Ther. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kenyon SL et al. | Broad-spectrum antibiotics for preterm, prelabour rupture of fetal membranes: the ORACLE I randomised trial. ORACLE Collaborative Group. | 2001 | Lancet | pmid:11293640 |
| Kenyon SL et al. | Broad-spectrum antibiotics for spontaneous preterm labour: the ORACLE II randomised trial. ORACLE Collaborative Group. | 2001 | Lancet | pmid:11293641 |
| Kanazawa S et al. | The effects of grapefruit juice on the pharmacokinetics of erythromycin. | 2001 Jan-Feb | Eur. J. Clin. Pharmacol. | pmid:11294369 |
| Craft JC | ABT-773 overview. | 2001 | Jpn J Antibiot | pmid:11296410 |
| Gunics G et al. | Enhanced antibacterial effect of erythromycin in the presence of 3,5-dibenzoyl-1,4-dihydropyridines. | 2001 Jan-Feb | Anticancer Res. | pmid:11299745 |
| Tsunoda SM et al. | Preliminary evaluation of progestins as inducers of cytochrome P450 3A4 activity in postmenopausal women. | 1998 | J Clin Pharmacol | pmid:11301566 |
| Ip M et al. | Macrolide resistance in Streptococcus pneumoniae in Hong Kong. | 2001 | Antimicrob. Agents Chemother. | pmid:11302833 |
| McGee L et al. | Serotype 19f multiresistant pneumococcal clone harboring two erythromycin resistance determinants (erm(B) and mef(A)) in South Africa. | 2001 | Antimicrob. Agents Chemother. | pmid:11302838 |
| Milne RW et al. | Hepatic disposition of fexofenadine: influence of the transport inhibitors erythromycin and dibromosulphothalein. | 2000 | Pharm. Res. | pmid:11303961 |
| Trepanier LA and Miller JL | NADH-dependent reduction of sulphamethoxazole hydroxylamine in dog and human liver microsomes. | 2000 | Xenobiotica | pmid:11307968 |
| Ripa S et al. | SmaI macrorestriction analysis of Italian isolates of erythromycin-resistant Streptococcus pyogenes and correlations with macrolide-resistance phenotypes. | 2001 | Microb. Drug Resist. | pmid:11310805 |
| Fogarty CM et al. | Effectiveness of levofloxacin for adult community-acquired pneumonia caused by macrolide-resistant Streptococcus pneumoniae: integrated results from four open-label, multicenter, phase III clinical trials. | 2001 | Clin Ther | pmid:11318077 |
| Ng PC et al. | Randomised controlled study of oral erythromycin for treatment of gastrointestinal dysmotility in preterm infants. | 2001 | Arch. Dis. Child. Fetal Neonatal Ed. | pmid:11320044 |
| Rouzica M and Filipová K | [On the article of J. Buchanec and V. Kdrajnák: Lesions of the liver during therapy with erythromycin in 3 children]. | 1975 | Cesk Pediatr | pmid:1132045 |
| Lanbeck P and Paulsen O | Short-term effects of four antibiotics on DNA synthesis in endothelial cells. | 2001 | Pharmacol. Toxicol. | pmid:11322179 |
| Kim HS et al. | Double-edged sword of chemosensitizer: increase of multidrug resistance protein (MRP) in leukemic cells by an MRP inhibitor probenecid. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11322768 |
| Weeda LW | Erythromycin and amoxicillin? | 2001 | J Tenn Dent Assoc | pmid:11324196 |
| From the Centers for Disease Control and Prevention. Sudden death in a traveler following halofantrine administration--Togo, 2000. | 2001 | JAMA | pmid:11324646 | |
| Rivory LP et al. | The erythromycin breath test for the prediction of drug clearance. | 2001 | Clin Pharmacokinet | pmid:11327195 |
| Tsuji SY et al. | Selective protein-protein interactions direct channeling of intermediates between polyketide synthase modules. | 2001 | Biochemistry | pmid:11327852 |
| Curry JI et al. | Review article: erythromycin as a prokinetic agent in infants and children. | 2001 | Aliment. Pharmacol. Ther. | pmid:11328252 |
| Martin SJ et al. | The activity of 14-hydroxy clarithromycin, alone and in combination with clarithromycin, against penicillin- and erythromycin-resistant Streptococcus pneumoniae. | 2001 | J. Antimicrob. Chemother. | pmid:11328768 |
| Zarantonelli L et al. | Decreased susceptibility to azithromycin and erythromycin mediated by a novel mtr(R) promoter mutation in Neisseria gonorrhoeae. | 2001 | J. Antimicrob. Chemother. | pmid:11328778 |
| Hattori A et al. | [A case of Folliculitis barbae Candidomycetica]. | 2001 | Nihon Ishinkin Gakkai Zasshi | pmid:11331469 |
| Ibarrola M et al. | [Disseminated disease by Mycobacterium kansasii resistant to isoniazid and rifampin in patients] with AIDS]. | 2001 | Enferm. Infecc. Microbiol. Clin. | pmid:11333577 |
| Gharpure V et al. | Efficacy of erythromycin for postpyloric placement of feeding tubes in critically ill children: a randomized, double-blind, placebo controlled study. | 2001 May-Jun | JPEN J Parenter Enteral Nutr | pmid:11334066 |
| Takiguchi Y et al. | Fulminant Mycoplasma pneumoniae pneumonia. | 2001 | Intern. Med. | pmid:11334397 |
| Hondeghem LM et al. | Phase 2 prolongation, in the absence of instability and triangulation, antagonizes class III proarrhythmia. | 2001 | Cardiovasc. Res. | pmid:11334838 |
| Gintant GA et al. | The canine Purkinje fiber: an in vitro model system for acquired long QT syndrome and drug-induced arrhythmogenesis. | 2001 | J. Cardiovasc. Pharmacol. | pmid:11336111 |
| Rawlings BJ | Type I polyketide biosynthesis in bacteria (Part A--erythromycin biosynthesis). | 2001 | Nat Prod Rep | pmid:11336289 |
| Samra Z et al. | In vitro susceptibility of recent clinical isolates of Chlamydia trachomatis to macrolides and tetracyclines. | 2001 | Diagn. Microbiol. Infect. Dis. | pmid:11337185 |
| Wang M et al. | Prevalence and phenotypes of erythromycin-resistant Streptococcus pneumoniae in Shanghai, China. | 2001 | Diagn. Microbiol. Infect. Dis. | pmid:11337187 |
| Corcoran JW | S-adenosylmethionine:erythromycin C O-methyltransferase. | 1975 | Meth. Enzymol. | pmid:1134368 |
| Dobbin CJ et al. | The efficacy of an antibiotic protocol for community-acquired pneumonia. | 2001 | Med. J. Aust. | pmid:11346105 |
| Akritopoulou-Zanze I and Sowin TJ | Solid-phase synthesis of macrolide analogues. | 2001 May-Jun | J Comb Chem | pmid:11350254 |
| Chitturi S and Farrell GC | Drug-induced cholestasis. | 2001 | Semin. Gastrointest. Dis. | pmid:11352118 |
| Bonnefoy A et al. | In vivo efficacy of the new ketolide telithromycin (HMR 3647) in murine infection models. | 2001 | Antimicrob. Agents Chemother. | pmid:11353612 |
| Marti GarcÃa JL et al. | [Rheumatic pneumonitis]. | 1975 | Rev Clin Esp | pmid:1135467 |
| Dujovne CA | Liver cell culture toxicity and surfactant potency of erythromycin derivatives. | 1975 | Toxicol. Appl. Pharmacol. | pmid:1135866 |
| Rowe CJ et al. | Engineering a polyketide with a longer chain by insertion of an extra module into the erythromycin-producing polyketide synthase. | 2001 | Chem. Biol. | pmid:11358694 |
| Ray RS et al. | Evaluation of UV-induced superoxide radical generation potential of some common antibiotics. | 2001 | Drug Chem Toxicol | pmid:11360435 |
| Germaniskis L and Singer EJ | HIV and peripheral neuropathy. | 1995 | J Int Assoc Physicians AIDS Care | pmid:11362726 |
| Takedomi S et al. | In-vivo kinetics of the interaction between midazolam and erythromycin in rats, taking account of metabolic intermediate complex formation. | 2001 | J. Pharm. Pharmacol. | pmid:11370704 |
| Sambol SP et al. | Infection of hamsters with epidemiologically important strains of Clostridium difficile. | 2001 | J. Infect. Dis. | pmid:11372028 |
| Fardis M et al. | Synthesis of 14,15-dehydroerythromycin A ketolides: effects of the 13-substituent on erythromycin tautomerism. | 2001 | J. Antibiot. | pmid:11372784 |
| Whitehead TR and Cotta MA | Sequence analyses of a broad host-range plasmid containing ermT from a tylosin-resistant Lactobacillus sp. Isolated from swine feces. | 2001 | Curr. Microbiol. | pmid:11375658 |
| Claesson K et al. | Sirolimus and erythromycin interaction: two cases. | 2001 | Transplant. Proc. | pmid:11377477 |
| Kim C et al. | The role of serine-246 in cytochrome P450eryF-catalyzed hydroxylation of 6-deoxyerythronolide B. | 2001 | Biosci. Biotechnol. Biochem. | pmid:11388449 |
| Fox KK et al. | Gonorrhea in the HIV era: a reversal in trends among men who have sex with men. | 2001 | Am J Public Health | pmid:11392941 |
| Sudden death in a traveler following halofantrine administration--Togo, 2000. | 2001 | MMWR Morb. Mortal. Wkly. Rep. | pmid:11393488 |