erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Airway Obstruction D000402 13 associated lipids
Tuberculosis D014376 20 associated lipids
Uremia D014511 33 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Nocardia Infections D009617 6 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Otitis Media D010033 12 associated lipids
Adenocarcinoma D000230 166 associated lipids
Bacterial Infections D001424 21 associated lipids
Otitis Externa D010032 8 associated lipids
Pain D010146 64 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Stomach Diseases D013272 7 associated lipids
Genital Diseases, Female D005831 7 associated lipids
Alveolitis, Extrinsic Allergic D000542 6 associated lipids
Per page 10 20 50 100 | Total 442

PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Chen C et al. Blocking the flow of propionate into TCA cycle through a mutB knockout leads to a significant increase of erythromycin production by an industrial strain of Saccharopolyspora erythraea. 2017 Bioprocess Biosyst Eng pmid:27709326
Gonser LI et al. Systemic therapy of ocular and cutaneous rosacea in children. 2017 J Eur Acad Dermatol Venereol pmid:28621909
Wang D et al. An analogous wood barrel theory to explain the occurrence of hormesis: A case study of sulfonamides and erythromycin on Escherichia coli growth. 2017 PLoS ONE pmid:28715457
Jia L et al. Synthesis and antibacterial evaluation of novel 11-O-carbamoyl clarithromycin ketolides. 2017 Bioorg. Med. Chem. Lett. pmid:28711353
Adhikari RP et al. Inducible clindamycin and methicillin resistant Staphylococcus aureus in a tertiary care hospital, Kathmandu, Nepal. 2017 BMC Infect. Dis. pmid:28693489
Wang HK et al. Clinical features and molecular characteristics of childhood community-associated methicillin-resistant Staphylococcus aureus infection in a medical center in northern Taiwan, 2012. 2017 BMC Infect. Dis. pmid:28679429
Haynes KM et al. Identification and Structure-Activity Relationships of Novel Compounds that Potentiate the Activities of Antibiotics in Escherichia coli. 2017 J. Med. Chem. pmid:28650638
Dalal A et al. Interventions for the prevention of recurrent erysipelas and cellulitis. 2017 Cochrane Database Syst Rev pmid:28631307
Štšepetova J et al. Assessment of phenotypic and genotypic antibiotic susceptibility of vaginal Lactobacillus sp. 2017 J. Appl. Microbiol. pmid:28574626
Tanaka Y et al. Applicability of ribosome engineering to vitamin B12 production by Propionibacterium shermanii. 2017 Biosci. Biotechnol. Biochem. pmid:28532245
Descours G et al. Ribosomal Mutations Conferring Macrolide Resistance in Legionella pneumophila. 2017 Antimicrob. Agents Chemother. pmid:28069647
Owen L et al. A Multifactorial Comparison of Ternary Combinations of Essential Oils in Topical Preparations to Current Antibiotic Prescription Therapies for the Control of Acne Vulgaris-Associated Bacteria. 2017 Phytother Res pmid:28124400
Chen K et al. Drug-resistance dynamics of Staphylococcus aureus between 2008 and 2014 at a tertiary teaching hospital, Jiangxi Province, China. 2017 BMC Infect. Dis. pmid:28122513
Berni E et al. Risk of cardiovascular events, arrhythmia and all-cause mortality associated with clarithromycin versus alternative antibiotics prescribed for respiratory tract infections: a retrospective cohort study. 2017 BMJ Open pmid:28115334
Wei L et al. Transformation of erythromycin during secondary effluent soil aquifer recharging: Removal contribution and degradation path. 2017 J Environ Sci (China) pmid:28115128
Koryakina I et al. Inversion of Extender Unit Selectivity in the Erythromycin Polyketide Synthase by Acyltransferase Domain Engineering. 2017 ACS Chem. Biol. pmid:28103677
Sugimoto N et al. Invasive pneumococcal disease caused by mucoid serotype 3 Streptococcus pneumoniae: a case report and literature review. 2017 BMC Res Notes pmid:28057059
Song KH et al. Characteristics of cefazolin inoculum effect-positive methicillin-susceptible staphylococcus aureus infection in a multicentre bacteraemia cohort. 2017 Eur. J. Clin. Microbiol. Infect. Dis. pmid:27714592
Kullin B et al. Toxin A-negative toxin B-positive ribotype 017 Clostridium difficile is the dominant strain type in patients with diarrhoea attending tuberculosis hospitals in Cape Town, South Africa. 2017 Eur. J. Clin. Microbiol. Infect. Dis. pmid:27696234
Pavlović D et al. Synthesis of novel 15-membered 8a-azahomoerythromycin A acylides: Consequences of structural modification at the C-3 and C-6 position on antibacterial activity. 2017 Eur J Med Chem pmid:27657812
Jakubů V et al. Trends in the Minimum Inhibitory Concentrations of Erythromycin, Clarithromycin, Azithromycin, Ciprofloxacin, and Trimethoprim/Sulfamethoxazole for Strains of Bordetella pertussis isolated in the Czech Republic in 1967-2015. 2017 Cent. Eur. J. Public Health pmid:29346850
Romero L et al. Macrolides for treatment of Haemophilus ducreyi infection in sexually active adults. 2017 Cochrane Database Syst Rev pmid:29226307
Naimi HM et al. Determination of antimicrobial susceptibility patterns in Staphylococcus aureus strains recovered from patients at two main health facilities in Kabul, Afghanistan. 2017 BMC Infect. Dis. pmid:29187146
Ricker EB and Nuxoll E Synergistic effects of heat and antibiotics on Pseudomonas aeruginosa biofilms. 2017 Biofouling pmid:29039211
Svetlov MS et al. Kinetics of drug-ribosome interactions defines the cidality of macrolide antibiotics. 2017 Proc. Natl. Acad. Sci. U.S.A. pmid:29229833
Atkinson CT et al. Expression of acquired macrolide resistance genes in Haemophilus influenzae. 2017 J. Antimicrob. Chemother. pmid:28961896
Wang B et al. Acid or erythromycin stress significantly improves transformation efficiency through regulating expression of DNA binding proteins in Lactococcus lactis F44. 2017 J. Dairy Sci. pmid:28987584
Quinn KL et al. Macrolides, Digoxin Toxicity and the Risk of Sudden Death: A Population-Based Study. 2017 Drug Saf pmid:28421551
Zhao L et al. Occurrence of erythromycin and its degradation products residues in honey. Validation of an analytical method. 2017 J Sep Sci pmid:28121061
Stieler AL et al. Macrolide-induced hyperthermia in foals: Role of impaired sweat responses. 2016 Equine Vet. J. pmid:26174202
Ulanovsky I et al. Erythromycin Prophylaxis for Neonatal Conjunctivitis: Ointment Versus Drops. 2016 Isr. Med. Assoc. J. pmid:28471562
Talebi M et al. Determination of Characteristics of Erythromycin Resistant Streptococcus pneumoniae with Preferred PCV Usage in Iran. 2016 PLoS ONE pmid:28033345
Ray D et al. Molecular characterization and evaluation of the emerging antibiotic-resistant Streptococcus pyogenes from eastern India. 2016 BMC Infect. Dis. pmid:27955635
Murchison L et al. Post-natal erythromycin exposure and risk of infantile hypertrophic pyloric stenosis: a systematic review and meta-analysis. 2016 Pediatr. Surg. Int. pmid:27655365
Dzyubak E and Yap MN The Expression of Antibiotic Resistance Methyltransferase Correlates with mRNA Stability Independently of Ribosome Stalling. 2016 Antimicrob. Agents Chemother. pmid:27645242
Abreu AC et al. Combinatorial approaches with selected phytochemicals to increase antibiotic efficacy against Staphylococcus aureus biofilms. 2016 Biofouling pmid:27643487
Jurado-Tarifa E et al. Genetic diversity and antimicrobial resistance of Campylobacter and Salmonella strains isolated from decoys and raptors. 2016 Comp. Immunol. Microbiol. Infect. Dis. pmid:27638115
Hu Z et al. Short-term performance of enhanced biological phosphorus removal (EBPR) system exposed to erythromycin (ERY) and oxytetracycline (OTC). 2016 Bioresour. Technol. pmid:27631889
Ghosh S and Banerjee M Methicillin resistance & inducible clindamycin resistance in Staphylococcus aureus. 2016 Indian J. Med. Res. pmid:27241651
Pignatello R et al. Synthesis, characterization and in vitro evaluation of amphiphilic ion pairs of erythromycin and kanamycin antibiotics with liposaccharides. 2016 Eur J Med Chem pmid:27236014
Mushtaq A et al. Differential Antimicrobial Susceptibilities of Granulicatella adiacens and Abiotrophia defectiva. 2016 Antimicrob. Agents Chemother. pmid:27216060
Hong M et al. Impacts of proline on the central metabolism of an industrial erythromycin-producing strain Saccharopolyspora erythraea via (13)C labeling experiments. 2016 J. Biotechnol. pmid:27215341
Baek YS et al. Antimicrobial resistance of Staphylococcus aureus isolated from skin infections and its implications in various clinical conditions in Korea. 2016 Int. J. Dermatol. pmid:26892888
Chua SL et al. Selective labelling and eradication of antibiotic-tolerant bacterial populations in Pseudomonas aeruginosa biofilms. 2016 Nat Commun pmid:26892159
Liu H et al. [A systematic review of the therapy for Mycoplasma pneumoniae infections in children]. 2016 Zhonghua Er Ke Za Zhi pmid:26875461
Poliquin V et al. Preparedness for Implementing Change in Neonatal Ocular Prophylaxis Policies. 2016 J Obstet Gynaecol Can pmid:26872748
Caspi M et al. A flow cytometry-based reporter assay identifies macrolide antibiotics as nonsense mutation read-through agents. 2016 J. Mol. Med. pmid:26620677
Sugawara A et al. Non-antibiotic 12-membered macrolides: design, synthesis and biological evaluation in a cigarette-smoking model. 2016 J. Antibiot. pmid:26419414
Brunel R and Charpentier X Trans-translation is essential in the human pathogen Legionella pneumophila. 2016 Sci Rep pmid:27892503
Yuan SF et al. Levels of six antibiotics used in China estimated by means of wastewater-based epidemiology. 2016 Water Sci. Technol. pmid:26901719