erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Lung Neoplasms D008175 171 associated lipids
Adenocarcinoma D000230 166 associated lipids
Edema D004487 152 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hemolysis D006461 131 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Inflammation D007249 119 associated lipids
Hypertension D006973 115 associated lipids
Weight Gain D015430 101 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Seizures D012640 87 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Leukemia D007938 74 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Pain D010146 64 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Psoriasis D011565 47 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Leukemia P388 D007941 43 associated lipids
Hypotension D007022 41 associated lipids
Arthritis D001168 41 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Chemical and Drug Induced Liver Injury D056486 39 associated lipids
Nervous System Diseases D009422 37 associated lipids
Lung Diseases D008171 37 associated lipids
Heart Failure D006333 36 associated lipids
Acne Vulgaris D000152 35 associated lipids
Glomerulonephritis D005921 35 associated lipids
Epilepsy D004827 35 associated lipids
Fever D005334 35 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Acute Lung Injury D055371 33 associated lipids
Peripheral Nervous System Diseases D010523 33 associated lipids
Uremia D014511 33 associated lipids
Diarrhea D003967 32 associated lipids
Cardiomegaly D006332 31 associated lipids
Liver Diseases D008107 31 associated lipids
Drug Eruptions D003875 30 associated lipids
Dermatitis D003872 30 associated lipids
Obesity D009765 29 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Nasal Polyps D009298 26 associated lipids
Pseudomonas Infections D011552 25 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
He Z and Li Y [Diffuse panbronchiolitis]. 1996 Zhonghua Jie He He Hu Xi Za Zhi pmid:9388854
Huang JQ and Xie CM [The effects of erythromycin on the secretion of tumor necrosis factor-alpha and transforming growth factor-beta1 and expression of connexin 43 in human pleural mesothelial cells]. 2003 Zhonghua Jie He He Hu Xi Za Zhi pmid:12901826
Wang BF [A clinical study of 50 cases of Legionnaires disease]. 1992 Zhonghua Jie He He Hu Xi Za Zhi pmid:1306405
Yu L and Ran PX [Effects of erythromycin on the synthesis of interleukin-8 and gamma-glutamylcysteine synthetase induced by 4-hydroxynonenal in the bronchial epithelial cells]. 2009 Zhonghua Jie He He Hu Xi Za Zhi pmid:19567187
Gao W et al. [Analysis of 9 cases of pulmonary tuberculosis complicated with legionnaires disease]. 1997 Zhonghua Jie He He Hu Xi Za Zhi pmid:10374448
Xu Z et al. [Effects of erythromycin and fosfomycin on Pseudomonas aeruginosa biofilm in vitro]. 2001 Zhonghua Jie He He Hu Xi Za Zhi pmid:11802985
Gu XH et al. [Effects of erythromycin on the twitching motility of Pseudomonas aeruginosa]. 2007 Zhonghua Jie He He Hu Xi Za Zhi pmid:17573001
Xia AF [Effect of oculentum erythromycin in the prevention of inflammatory conjunctivitis of neonates]. 1993 Zhonghua Hu Li Za Zhi pmid:8339361
Li X [Combination of commonly used antibiotics in intravenous infusions]. 1991 Zhonghua Hu Li Za Zhi pmid:1889101
Zhang RL et al. [Study on interventional methods and the pattern of maternal-fetal transmission of syphilis during pregnancy]. 2007 Zhonghua Fu Chan Ke Za Zhi pmid:17961330
Zhang FC [Radiologic manifestations of Legionnaires' disease (report of 2 cases)]. 1985 Zhonghua Fang She Xue Za Zhi pmid:2938897
Ding YF et al. [Relation of pbp2B, ermB, ermA/B, mefA genes with resistance to penicillin and erythromycin among Streptococcus pneumoniae isolates from children]. 2005 Zhonghua Er Ke Za Zhi pmid:15924755
Hua CZ et al. [Antibiotics-resistance pattern and genetic type of Streptococcus pneumoniae isolated from children in Hangzhou]. 2004 Zhonghua Er Ke Za Zhi pmid:14990098
Ge LL et al. [Antibiotic resistance analysis of isolates from the hospitalized children in Shanxi Children's Hospital from 2012 to 2014]. 2017 Zhonghua Er Ke Za Zhi pmid:28173648
Su WD et al. [Chymothorax in a newborn infant]. 2003 Zhonghua Er Ke Za Zhi pmid:14723819
He S et al. [Clinical analysis of scrub typhus-associated hemophagocytic syndrome]. 2014 Zhonghua Er Ke Za Zhi pmid:25476431
Sun ZY et al. [Epidemiological study of Streptococcus pneumoniae in the nasopharynx of healthy children under 5 years of age in Wuhan]. 2007 Zhonghua Er Ke Za Zhi pmid:17697628
Hua CZ et al. [An analysis of 181 cases with blood stream infection caused by Streptococcus agalactiae in children from 2011 to 2015: a multi-center retrospective study]. 2016 Zhonghua Er Ke Za Zhi pmid:27510868
Wang CH et al. [Effect of interstitial cells of Cajal on gastrointestinal motility induced by motilin receptor agonist ABT-229]. 2010 Zhonghua Er Ke Za Zhi pmid:20654011
Liu H et al. [A systematic review of the therapy for Mycoplasma pneumoniae infections in children]. 2016 Zhonghua Er Ke Za Zhi pmid:26875461
He JX et al. [Demonstration of a mechanism of anti-inflammatory effect of erythromycin on allergic airway inflammation in rat]. 2005 Zhonghua Er Ke Za Zhi pmid:15833193
Yang H et al. [Macrolide-resistant Streptococcus pneumoniae in the pediatric population in Beijing]. 2004 Zhonghua Er Ke Za Zhi pmid:15733368
Hua CZ et al. [Drug-resistance of staphylococcus aureus and detection of mecA gene in all strains isolated from children in Hangzhou]. 2006 Zhonghua Er Ke Za Zhi pmid:16780714
Xu SN et al. [Effect of erythromycin on apoptosis of epithelial cell in nasal polyps]. 2006 Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi pmid:17007374
Tang J and Li Y [Effect of erythromycin on the expression of apoptotic gene on eosinophils in nasal polyps in vitro]. 2003 Zhonghua Er Bi Yan Hou Ke Za Zhi pmid:15040110
Tang J et al. [Effect of erythromycin on apoptosis of eosinophils in nasal polyps in vitro]. 2002 Zhonghua Er Bi Yan Hou Ke Za Zhi pmid:12768725
Guan Y et al. [Effect of combination of sub-MIC sodium houttuyfonate and erythromycin on biofilm of Staphylococcus epidermidis]. 2013 Zhongguo Zhong Yao Za Zhi pmid:23724685
Guan Y et al. [Preliminary study of effects of andrographolide on Staphylococcus epidermidis biofilms]. 2012 Zhongguo Zhong Yao Za Zhi pmid:23126203
Jia P et al. [Regulative effect of electroacupuncture of different frequencies on derangement of gastric electric rhythm in rabbits]. 2006 Zhongguo Zhen Jiu pmid:17165505
Sun XR et al. [Effect of motilin receptor agonist-erythromycin on the glucose responsive neurons in hypothalamus of rats]. 2005 Zhongguo Ying Yong Sheng Li Xue Za Zhi pmid:21162186
Yu I et al. [The effects of the erythromycin on the production of r-glutamylcys glutamylcysteine synthetase and glutathione in the bronchial epithelial cell]. 2009 Zhongguo Ying Yong Sheng Li Xue Za Zhi pmid:21186628
Lei PS et al. [Advance in synthesis of ketolides, a new class of erythromycin derivatives]. 2004 Zhongguo Yi Xue Ke Xue Yuan Xue Bao pmid:15379279
Wang H et al. Demethylation capacity of human fetal adrenal mitochondrial cytochrome P-450 in vitro. 1999 Zhongguo Yao Li Xue Bao pmid:10452125
Huang SK et al. [A combined perfusion-compartmental pharmacokinetic model used to estimate presystemic metabolism of erythromycin in dogs]. 1986 Zhongguo Yao Li Xue Bao pmid:2954396
Ye H et al. Antimycoplasmal activities of (S)-(-)-9-fluoro-2,3-dihydro-3-methyl-10 -[4-(2-pyridyl)-1-piperazinyl]-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine -6-carboxylic acid (YH-6) in comparison with other antibiotics in vitro. 1999 Zhongguo Yao Li Xue Bao pmid:11270970
Du Y and He Q [The mechanism of alleviation of paraquat induced vascular endothelial permeability by erythromycin through adenosine 3'5'-cyclic monophosphate pathway]. 2009 Zhongguo Wei Zhong Bing Ji Jiu Yi Xue pmid:19930884
Lu NF et al. [Study of erythromycin and metoclopramide in treatment of feeding intolerance of critically ill patients in intensive care unit]. 2010 Zhongguo Wei Zhong Bing Ji Jiu Yi Xue pmid:20092709
Yu M et al. [Mechanism reversing MDR of K562/A02 by garlicin combined with erythromycin]. 2008 Zhongguo Shi Yan Xue Ye Xue Za Zhi pmid:18928592
Xie L et al. [Efficacy of low-dose oral erythromycin as an adjuvant therapy for cytomegalovirus infection]. 2010 Zhongguo Dang Dai Er Ke Za Zhi pmid:20199738
Yang Y [Mechanism and clinical application of erythromycin as a gastrointestinal prokinetic agent in children]. 2008 Zhongguo Dang Dai Er Ke Za Zhi pmid:18289489
Thomas W and Speer CP Prevention and therapy of bronchopulmonary dysplasia - evidence and clinical practice. 2007 Zhongguo Dang Dai Er Ke Za Zhi pmid:17582275
Wang LQ et al. [Pharmacokinetics of erythromycin stinoprate capsule]. 2005 Zhong Nan Da Xue Xue Bao Yi Xue Ban pmid:15898434
Lin XM et al. [Influence of neferine and erythromycin on cellular GSH concentration in K562/A02 cell line]. 2004 Zhong Nan Da Xue Xue Bao Yi Xue Ban pmid:16136961
Xu G [Regulating effect of electro-acupuncture on dysrythmia of gastro-colonic electric activity induced by erythromycine in rabbits]. 1994 Zhen Ci Yan Jiu pmid:7834859
Wu DQ et al. [The expression of transforming growth factor beta-1 in rat model of chronic obstructive pulmonary disease and the effects of early drugs intervention]. 2004 Zhejiang Da Xue Xue Bao Yi Xue Ban pmid:15476327
Liashenko IuI [Humoral immunity indices in angina and chronic tonsillitis and the effect on it of antibiotics]. 1978 Zh. Mikrobiol. Epidemiol. Immunobiol. pmid:665045
Klimchuk ND [Preventive effect of several antibiotics in experimental rickettsial infections]. 1978 Zh. Mikrobiol. Epidemiol. Immunobiol. pmid:742277
Gamaleia NB and Levashev VS [Biological properties and mechanisms of development of bacteria resistant to fusidin, erythromycin and chloramphenicol]. 1978 Zh. Mikrobiol. Epidemiol. Immunobiol. pmid:96638
Klimchuk ND [The effect of various antibiotics on the formation of typhus antibodies following immunization with typhus vaccine]. 1978 Zh. Mikrobiol. Epidemiol. Immunobiol. pmid:97881
Solov'eva SV et al. [Detection of tetracycline- and erythromycin-resistant urogenital Mycoplasma strains using PCR]. 1998 Nov-Dec Zh. Mikrobiol. Epidemiol. Immunobiol. pmid:9949490