erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Drug-Related Side Effects and Adverse Reactions D064420 3 associated lipids
Vagus Nerve Injuries D061223 1 associated lipids
Occupational Injuries D060051 1 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Chemical and Drug Induced Liver Injury D056486 39 associated lipids
Acute Lung Injury D055371 33 associated lipids
Atrioventricular Block D054537 1 associated lipids
Pneumonia, Ventilator-Associated D053717 1 associated lipids
Kidney Diseases, Cystic D052177 3 associated lipids
Granulomatosis, Orofacial D051261 2 associated lipids
Seroma D049291 2 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Pyloric Stenosis, Hypertrophic D046248 2 associated lipids
Moraxellaceae Infections D045828 3 associated lipids
Desulfovibrionaceae Infections D045824 5 associated lipids
Ileus D045823 3 associated lipids
Acalculous Cholecystitis D042101 3 associated lipids
Pelvic Infection D034161 1 associated lipids
Communicable Diseases, Emerging D021821 3 associated lipids
Neuroaspergillosis D020953 2 associated lipids
Epidural Abscess D020802 1 associated lipids
Enterocolitis, Necrotizing D020345 3 associated lipids
Postoperative Nausea and Vomiting D020250 1 associated lipids
Dermatitis, Perioral D019557 4 associated lipids
Postoperative Hemorrhage D019106 7 associated lipids
Sepsis D018805 11 associated lipids
Abdominal Abscess D018784 2 associated lipids
Arthralgia D018771 8 associated lipids
Gastroparesis D018589 2 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Lymphoma, B-Cell, Marginal Zone D018442 1 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Adrenocortical Carcinoma D018268 4 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
Limb Deformities, Congenital D017880 4 associated lipids
Granuloma, Pyogenic D017789 2 associated lipids
Community-Acquired Infections D017714 8 associated lipids
Retropharyngeal Abscess D017703 2 associated lipids
Lung Diseases, Interstitial D017563 5 associated lipids
Pityriasis Rosea D017515 3 associated lipids
Pityriasis Lichenoides D017514 2 associated lipids
Acneiform Eruptions D017486 3 associated lipids
Skin Diseases, Vascular D017445 1 associated lipids
Skin Diseases, Papulosquamous D017444 2 associated lipids
Gastric Outlet Obstruction D017219 1 associated lipids
Skin Diseases, Viral D017193 2 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Tachycardia, Ventricular D017180 9 associated lipids
AIDS-Related Opportunistic Infections D017088 9 associated lipids
Chalazion D017043 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Ragosta M et al. Potentially fatal interaction between erythromycin and disopyramide. 1989 Am. J. Med. pmid:2467560
Gumaste VV Erythromycin-induced pancreatitis. 1989 Am. J. Med. pmid:2729328
Curtis LH et al. Prescription of QT-prolonging drugs in a cohort of about 5 million outpatients. 2003 Am. J. Med. pmid:12586234
Cameron DJ Effectiveness of early Lyme disease treatment. 1993 Am. J. Med. pmid:8388627
Naot Y et al. IgM and IgG antibody response in two immunosuppressed patients with Legionnaires' disease. Evidence of reactivation of latent infection. 1982 Am. J. Med. pmid:6756135
Klein JO Emerging perspectives in management and prevention of infections of the respiratory tract in infants and children. 1985 Am. J. Med. pmid:4014286
Rudin JE et al. Failure of erythromycin in treatment of Legionella micdadei pneumonia. 1984 Am. J. Med. pmid:6607673
Sacristán JA and Soto J Erythromycin ototoxicity: methodology and conclusions. 1993 Am. J. Med. pmid:8430720
Wong KF et al. Psittacosis-associated hemophagocytic syndrome. 1991 Am. J. Med. pmid:1867249
Lipsky BA et al. Ofloxacin treatment of Chlamydia pneumoniae (strain TWAR) lower respiratory tract infections. 1990 Am. J. Med. pmid:2252040
Tablan OC and Reyes MP Chronic interstitial pulmonary fibrosis following Mycoplasma pneumoniae pneumonia. 1985 Am. J. Med. pmid:4025379
Vianna NJ and Hinman AR Rocky Mountain spotted fever on Long Island. Epidemiologic and clinical aspects. 1971 Am. J. Med. pmid:5129543
Augenbraun MH et al. Chlamydia pneumoniae pneumonia with pleural effusion: diagnosis by culture. 1991 Am. J. Med. pmid:1951390
Massarotti EM et al. Treatment of early Lyme disease. 1992 Am. J. Med. pmid:1313637
Swanson DJ et al. Erythromycin ototoxicity: prospective assessment with serum concentrations and audiograms in a study of patients with pneumonia. 1992 Am. J. Med. pmid:1731511
Kugler JW et al. Nosocomial Legionnaires' disease. Occurrence in recipients of bone marrow transplants. 1983 Am. J. Med. pmid:6337488
Petersdorf RG Antimicrobial prophylaxis of bacterial endocarditis. Prudent caution or bacterial overkill? 1978 Am. J. Med. pmid:99033
Moellering RC et al. Endocarditis due to group D streptococci. Comparison of disease caused by streptococcus bovis with that produced by the enterococci. 1974 Am. J. Med. pmid:4843895
Moellering RC Introduction: revolutionary changes in the macrolide and azalide antibiotics. 1991 Am. J. Med. pmid:1656735
Neu HC Clinical microbiology of azithromycin. 1991 Am. J. Med. pmid:1656736
Bent S et al. Antibiotics in acute bronchitis: a meta-analysis. 1999 Am. J. Med. pmid:10403354
Stamm WE Azithromycin in the treatment of uncomplicated genital chlamydial infections. 1991 Am. J. Med. pmid:1656737
Hooton TM A comparison of azithromycin and penicillin V for the treatment of streptococcal pharyngitis. 1991 Am. J. Med. pmid:1656738
Casiano RR Azithromycin and amoxicillin in the treatment of acute maxillary sinusitis. 1991 Am. J. Med. pmid:1656739
Dark D Multicenter evaluation of azithromycin and cefaclor in acute lower respiratory tract infections. 1991 Am. J. Med. pmid:1656740
Mallory SB Azithromycin compared with cephalexin in the treatment of skin and skin structure infections. 1991 Am. J. Med. pmid:1656741
Hopkins S Clinical toleration and safety of azithromycin. 1991 Am. J. Med. pmid:1656742
Friedland L et al. Ocular and pericardial involvement in Legionnaires' disease. 1984 Am. J. Med. pmid:6507461
Schentag JJ and Ballow CH Tissue-directed pharmacokinetics. 1991 Am. J. Med. pmid:1656743
Nichols RL Use of prophylactic antibiotics in surgical practice. 1981 Am. J. Med. pmid:7011021
Wing EJ et al. Successful treatment of Legionella micdadei (Pittsburgh pneumonia agent) pneumonia with erythromycin. 1981 Am. J. Med. pmid:7304656
Bolton WK et al. Ventriculojugular shunt nephritis with Corynebacterium bovis. Successful therapy with antibiotics. 1975 Am. J. Med. pmid:1163549
Nastro LJ and Finegold SM Endocarditis due to anaerobic gram-negative bacilli. 1973 Am. J. Med. pmid:4696007
Quintiliani R and Hymans PJ The association of bacteremic Haemophilus influenzae pneumonia in adults with typable strains. 1971 Am. J. Med. pmid:5314534
Watanakunakorn C Clindamycin therapy of Staphylococcus aureus endocarditis. Clinical relapse and development of resistance to clindamycin, lincomycin and erythromycin. 1976 Am. J. Med. pmid:1045861
Bowler WA et al. Gastrointestinal side effects of intravenous erythromycin: incidence and reduction with prolonged infusion time and glycopyrrolate pretreatment. 1992 Am. J. Med. pmid:1546723
Singer DR et al. Drug hypersensitivity causing granulomatous interstitial nephritis. 1988 Am. J. Kidney Dis. pmid:3354573
Martínez-Maldonado M Postinfectious glomerulonephritis. 2000 Am. J. Kidney Dis. pmid:10636819
Mery JP and Kanfer A Alterations in pharmacokinetics and ototoxicity of erythromycin in renal failure. 1984 Am. J. Kidney Dis. pmid:6741942
Silang R et al. Prokinetic agents increase plasma albumin in hypoalbuminemic chronic dialysis patients with delayed gastric emptying. 2001 Am. J. Kidney Dis. pmid:11157368
Ross EA and Koo LC Improved nutrition after the detection and treatment of occult gastroparesis in nondiabetic dialysis patients. 1998 Am. J. Kidney Dis. pmid:9428453
Tanaka M et al. Agranulocytosis induced by macrolide antibiotics. 1995 Am. J. Hematol. pmid:7847332
Janssen P et al. The relation between symptom improvement and gastric emptying in the treatment of diabetic and idiopathic gastroparesis. 2013 Am. J. Gastroenterol. pmid:24005344
DITTLER EL Upper abdominal pain and intrahepatic cholestasis as manifestations of sensitivity to ilosone. 1962 Am. J. Gastroenterol. pmid:14028076
Rayner CK et al. The stimulation of antral motility by erythromycin is attenuated by hyperglycemia. 2000 Am. J. Gastroenterol. pmid:11007223
Weber FH et al. Erythromycin: a motilin agonist and gastrointestinal prokinetic agent. 1993 Am. J. Gastroenterol. pmid:8470625
McNulty CA The treatment of Campylobacter-associated gastritis. 1987 Am. J. Gastroenterol. pmid:3493685
Koutsoumbi P et al. The effect of erythromycin on human esophageal motility is mediated by serotonin receptors. 2000 Am. J. Gastroenterol. pmid:11151866
Portincasa P et al. The effect of acute oral erythromycin on gallbladder motility and on upper gastrointestinal symptoms in gastrectomized patients with and without gallstones: a randomized, placebo-controlled ultrasonographic study. 2000 Am. J. Gastroenterol. pmid:11151875
Ecker JA et al. Pseudomembraneous enterocolitis--an unwelcome gastrointestinal complication of antibiotic therapy. 1970 Am. J. Gastroenterol. pmid:4319211