erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Classen DC et al. | Clinical and financial impact of intravenous erythromycin therapy in hospitalized patients. | 1999 | Ann Pharmacother | pmid:10410176 |
Lacey RW and Lewis EL | Further evolution of a strain of Staphylococcus aureus in vivo: evidence for significant inactivation of flucloxacillin by penicillinase. | 1975 | J. Med. Microbiol. | pmid:1040676 |
Ullmann U et al. | Comparative in-vitro activity of levofloxacin, other fluoroquinolones, doxycycline and erythromycin against Ureaplasma urealyticum and Mycoplasma hominis. | 1999 | J. Antimicrob. Chemother. | pmid:10404335 |
Bent S et al. | Antibiotics in acute bronchitis: a meta-analysis. | 1999 | Am. J. Med. | pmid:10403354 |
Vesce F et al. | Effect of different classes of antibiotics on amniotic prostaglandin E release. | 1999 | Prostaglandins Other Lipid Mediat. | pmid:10402215 |
Watanabe M et al. | Role of CYP3A in haloperidol N-dealkylation and pharmacokinetics in rats. | 1999 | Fundam Clin Pharmacol | pmid:10392310 |
Kawanami R et al. | [Successful treatment of allergic bronchopulmonary aspergillosis with erythromycin and fluconazole]. | 1999 | Nihon Kokyuki Gakkai Zasshi | pmid:10390974 |
Mazzei T et al. | Pharmacokinetics of dirithromycin in patients with mild or moderate cirrhosis. | 1999 | Antimicrob. Agents Chemother. | pmid:10390202 |
Tanaka T et al. | Effect of EM574 on postprandial pancreaticobiliary secretion, gastric motor activity, and emptying in conscious dogs. | 1999 | Dig. Dis. Sci. | pmid:10389679 |
Cook M and Lynch WH | A sensitive nested reverse transcriptase PCR assay to detect viable cells of the fish pathogen Renibacterium salmoninarum in Atlantic salmon (Salmo salar L.). | 1999 | Appl. Environ. Microbiol. | pmid:10388701 |
Francis GS | Cardiac complications in the intensive care unit. | 1999 | Clin. Chest Med. | pmid:10386256 |
Valisena S et al. | Molecular typing of erythromycin-resistant streptococcus pyogenes strains with the M phenotype isolated in Italy. | 1999 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:10385014 |
Tzelepi E et al. | Erythromycin resistance amongst group A beta-haemolytic streptococci isolated in a paediatric hospital in Athens, Greece. | 1999 | J. Antimicrob. Chemother. | pmid:10382903 |
McConnell SA et al. | Lack of effect of dirithromycin on theophylline pharmacokinetics in healthy volunteers. | 1999 | J. Antimicrob. Chemother. | pmid:10382900 |
Bébéar CM et al. | In-vitro activity of grepafloxacin, a new fluoroquinolone, against mycoplasmas. | 1999 | J. Antimicrob. Chemother. | pmid:10382895 |
Nishijima T et al. | Distribution of mefE and ermB genes in macrolide-resistant strains of Streptococcus pneumoniae and their variable susceptibility to various antibiotics. | 1999 | J. Antimicrob. Chemother. | pmid:10382884 |
Ruckdeschel G and Dalhoff A | The in-vitro activity of moxifloxacin against Legionella species and the effects of medium on susceptibility test results. | 1999 | J. Antimicrob. Chemother. | pmid:10382872 |
Feighner SD et al. | Receptor for motilin identified in the human gastrointestinal system. | 1999 | Science | pmid:10381885 |
Huber R et al. | Increase of cellular hypoxic tolerance by erythromycin and other antibiotics. | 1999 | Neuroreport | pmid:10380977 |
Hägg S et al. | Absence of interaction between erythromycin and a single dose of clozapine. | 1999 | Eur. J. Clin. Pharmacol. | pmid:10379638 |
Griga T et al. | [Effect of stomach motility on measuring stomach permeability with saccharose in vivo]. | 1999 | Z Gastroenterol | pmid:10378362 |
Alvarez-Elcoro S and Enzler MJ | The macrolides: erythromycin, clarithromycin, and azithromycin. | 1999 | Mayo Clin. Proc. | pmid:10377939 |
Taege AJ | Listeriosis: recognizing it, treating it, preventing it. | 1999 | Cleve Clin J Med | pmid:10375847 |
Gao W et al. | [Analysis of 9 cases of pulmonary tuberculosis complicated with legionnaires disease]. | 1997 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:10374448 |
Hume EB et al. | Clarithromycin for experimental Staphylococcus aureus keratitis. | 1999 | Curr. Eye Res. | pmid:10372997 |
Arum ES and Jacobs NF | Nongonococcal urethritis. | 1976 | Cutis | pmid:1037101 |
Gregory ST and Dahlberg AE | Erythromycin resistance mutations in ribosomal proteins L22 and L4 perturb the higher order structure of 23 S ribosomal RNA. | 1999 | J. Mol. Biol. | pmid:10369764 |
Cilostazol for intermittent claudication. | 1999 | Med Lett Drugs Ther | pmid:10368703 | |
Petrakis IE et al. | Hyperglycaemia attenuates erythromycin-induced acceleration of solid-phase gastric emptying in idiopathic and diabetic gastroparesis. | 1999 | Scand. J. Gastroenterol. | pmid:10365900 |
Schulte W et al. | [Diffuse panbronchiolitis. A rare differential diagnosis of chronic obstructive lung disease]. | 1999 | Dtsch. Med. Wochenschr. | pmid:10365176 |
Tamayo M et al. | Dissemination of a chloramphenicol- and tetracycline-resistant but penicillin-susceptible invasive clone of serotype 5 Streptococcus pneumoniae in Colombia. | 1999 | J. Clin. Microbiol. | pmid:10364609 |
Viñado B et al. | [Resistance to erythromycin in strains of Streptococcus pyogenes isolated in the province of Barcelona]. | 1999 | Med Clin (Barc) | pmid:10363246 |
Irokawa T et al. | Cholinomimetic action of macrolide antibiotics on airway gland electrolyte secretion. | 1999 | Am. J. Physiol. | pmid:10362719 |
Janovska D et al. | Administration of antibiotics in combination. Determination of antibacterial effectivity of blood serum and urine after simultaneous administration of macrolides and tetracyclines. | 1976 | J Hyg Epidemiol Microbiol Immunol | pmid:1035924 |
Kalima P et al. | Epidemiology of Streptococcus pneumoniae infections at the Edinburgh City Hospital: 1980-95. | 1999 | Epidemiol. Infect. | pmid:10355789 |
Leal AL and Castañeda E | [Susceptibility to antimicrobial agents in isolates from invasive Streptococcus pneumoniae in Colombia]. | 1999 | Rev. Panam. Salud Publica | pmid:10355313 |
Erickson PR and Herzberg MC | Emergence of antibiotic resistant Streptococcus sanguis in dental plaque of children after frequent antibiotic therapy. | 1999 May-Jun | Pediatr Dent | pmid:10355009 |
Fearfield LA and Staughton RC | Severe vulval apocrine acne successfully treated with prednisolone and isotretinoin. | 1999 | Clin. Exp. Dermatol. | pmid:10354177 |
Rosato A et al. | Inducible or constitutive expression of resistance in clinical isolates of streptococci and enterococci cross-resistant to erythromycin and lincomycin. | 1999 | J. Antimicrob. Chemother. | pmid:10350387 |
Wasilewski MM et al. | Five-day dirithromycin therapy is as effective as seven-day erythromycin therapy for acute exacerbations of chronic bronchitis. | 1999 | J. Antimicrob. Chemother. | pmid:10350384 |
Simon MW | Treatment of acute sinusitis in childhood with ceftibuten. | 1999 | Clin Pediatr (Phila) | pmid:10349523 |
Greiver M | Practice tips. Incorporating a rapid group A streptococcus assay with the sore throat score. | 1999 | Can Fam Physician | pmid:10349060 |
Roberts MC et al. | Erythromycin-resistant Neisseria gonorrhoeae and oral commensal Neisseria spp. carry known rRNA methylase genes. | 1999 | Antimicrob. Agents Chemother. | pmid:10348754 |
Champney WS and Tober CL | Molecular investigation of the postantibiotic effects of clarithromycin and erythromycin on Staphylococcus aureus cells. | 1999 | Antimicrob. Agents Chemother. | pmid:10348746 |
Dujovne CA | Experimental investigations on the different hepatotoxic potential of erythromycin derivatives. | 1976 | Med Chir Dig | pmid:1034861 |
Mikami Y et al. | Production of erythromycin E by pathogenic Nocardia brasiliensis. | 1999 | J. Antibiot. | pmid:10344579 |
Parsons IC et al. | Structural elucidation of a novel erythromycin, 13-cyclopentyl-13-desethyl-erythromycin B, from a recombinant Saccharopolyspora erythraea strain, NRRL 2338 pIG/1. | 1999 | J. Antibiot. | pmid:10344576 |
Levert H et al. | Time and concentration dependent influence of dirithromycin on neutrophils oxidative burst. | 1999 | J. Antibiot. | pmid:10344566 |
Mertens PR et al. | Long-term extracorporeal bilirubin elimination: A case report on cascade resin plasmaperfusion. | 1998 | Blood Purif. | pmid:10343081 |
Dornbusch K et al. | Postantibiotic effect and postantibiotic sub-mic effect of dirithromycin and erythromycin against respiratory tract pathogenic bacteria. | 1999 | APMIS | pmid:10335955 |