erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Heggie AD et al. | Topical sulfacetamide vs oral erythromycin for neonatal chlamydial conjunctivitis. | 1985 | Am. J. Dis. Child. | pmid:3890519 |
Patamasucon P et al. | Oral v topical erythromycin therapies for chlamydial conjunctivitis. | 1982 | Am. J. Dis. Child. | pmid:7051813 |
Rodriguez WJ et al. | Erythromycin-sulfisoxazole vs amoxicillin in the treatment of acute otitis media in children. A double-blind, multiple-dose comparative study. | 1985 | Am. J. Dis. Child. | pmid:3895889 |
BURNS L and HODGMAN J | STUDIES OF PREMATURES GIVEN ERYTHROMYCIN ESTOLATE. | 1963 | Am. J. Dis. Child. | pmid:14057607 |
Bass JW et al. | Antimicrobials in the treatment of acute otitis media. A second clinical trial. | 1973 | Am. J. Dis. Child. | pmid:4632555 |
Maruyama S et al. | Sensitivity of group A streptococci to antibiotics. Prevalence of resistance to erythromycin in Japan. | 1979 | Am. J. Dis. Child. | pmid:389035 |
Derrick CW and Dillon HC | Streptococcal pharyngitis therapy. A comparison of two erythromycin formulations. | 1979 | Am. J. Dis. Child. | pmid:389036 |
Pai CH et al. | Erythromycin in treatment of Campylobacter enteritis in children. | 1983 | Am. J. Dis. Child. | pmid:6600579 |
Disney FA and Pichichero ME | Treatment of Staphylococcus aureus infections in children in office practice. | 1983 | Am. J. Dis. Child. | pmid:6600877 |
Aiello LF and Luby JP | Concomitant Mycoplasma and adenovirus infection in a family. | 1974 | Am. J. Dis. Child. | pmid:4374082 |
Lloyd-Still JD et al. | Erythromycin estolate hepatotoxicity. | 1978 | Am. J. Dis. Child. | pmid:629252 |
Wannamaker LW | Perplexity and precision in the diagnosis of streptococcal pharyngitis. | 1972 | Am. J. Dis. Child. | pmid:5056872 |
Fischer PR and Shigeoka AO | Familial occurrence of Stevens-Johnson syndrome. | 1983 | Am. J. Dis. Child. | pmid:6604452 |
HUXTABLE KA et al. | STAPHYLOCOCCAL PNEUMONIA IN CHILDHOOD; LONG-TERM FOLLOW-UP. | 1964 | Am. J. Dis. Child. | pmid:14168063 |
Feigin RD et al. | Osteomyelitis of the calcaneus. Report of eight cases. | 1970 | Am. J. Dis. Child. | pmid:5410295 |
Demidovich CW et al. | Impetigo. Current etiology and comparison of penicillin, erythromycin, and cephalexin therapies. | 1990 | Am. J. Dis. Child. | pmid:2244610 |
Ginsburg CM et al. | Erythromycin therapy for group A streptococcal pharyngitis. Results of a comparative study of the estolate and ethylsuccinate formulations. | 1984 | Am. J. Dis. Child. | pmid:6372437 |
Esterly NB et al. | Impetigo. | 1991 | Am. J. Dis. Child. | pmid:1899777 |
Hughes WT and Collier RN | Streptococcal pharyngitis. Evaluation of erythromycin, erythromycin-sulfas, and sulfamethoxazole (possible antagonism between erythromycin and sulfas). | 1969 | Am. J. Dis. Child. | pmid:5348368 |
Sprauer MA et al. | Prevention of secondary transmission of pertussis in households with early use of erythromycin. | 1992 | Am. J. Dis. Child. | pmid:1733147 |
Dillon HC and Ware JC | Sources and susceptibilities of staphylococci isolated from children. A seven-year survey. | 1981 | Am. J. Dis. Child. | pmid:7234768 |
Breese BB et al. | Streptococcal infections in children. Comparison of the therapeutic effectiveness of erythromycin administered twice daily with erythromycin, penicillin phenoxymethyl, and clindamycin administered three times daily. | 1974 | Am. J. Dis. Child. | pmid:4213398 |
Robins-Browne RM et al. | Treatment of Campylobacter-associated enteritis with erythromycin. | 1983 | Am. J. Dis. Child. | pmid:6337473 |
Barton LL and Friedman AD | Etiology and therapy of impetigo: reconsidered. | 1990 | Am. J. Dis. Child. | pmid:2305731 |
Drusin LM et al. | Group C streptococcal colonization in a newborn nursery. | 1973 | Am. J. Dis. Child. | pmid:4708274 |
Phair JP et al. | Penicillin phenoxymethyl. Use in rheumatic fever prophylaxis. | 1973 | Am. J. Dis. Child. | pmid:4198746 |
Harrison HS et al. | Congenital laryngeal cleft: report of a case. A comparison with other types of tracheo-esophageal communication. | 1965 | Am. J. Dis. Child. | pmid:5846694 |
Khuri-Bulos N et al. | Bacteroides brain abscess treated with clindamycin. | 1973 | Am. J. Dis. Child. | pmid:4723176 |
Stallings MW and Archer SB | Atypical Mycoplasma pneumonia. | 1973 | Am. J. Dis. Child. | pmid:4759371 |
Davis SD et al. | Partial antibiotic therapy in Haemophilus infuenzae meningitis. Its effect on cerebrospinal fluid abnormalities. | 1975 | Am. J. Dis. Child. | pmid:1080009 |
Wittler RR et al. | Penicillin tolerance and erythromycin resistance of group A beta-hemolytic streptococci in Hawaii and the Philippines. | 1990 | Am. J. Dis. Child. | pmid:2184661 |
Halsey NA et al. | Nosocomial pertussis: a failure of erythromycin treatment and prophylaxis. | 1980 | Am. J. Dis. Child. | pmid:7377164 |
Noonan JA et al. | Cerebral and cardiac complications from bacterial endocarditis. A successfully managed case with unusual complications. | 1968 | Am. J. Dis. Child. | pmid:5303294 |
Bruhn FW | Lyme disease. | 1984 | Am. J. Dis. Child. | pmid:6711502 |
Slotkin RI et al. | The effect of antibiotics on Mycoplasma pneumoniae in vitro and in vivo. | 1967 | Am. J. Epidemiol. | pmid:5006447 |
Tomomasa T et al. | Gastrointestinal sounds and migrating motor complex in fasted humans. | 1999 | Am. J. Gastroenterol. | pmid:10022632 |
Glupczynski Y and Burette A | Failure of azythromycin to eradicate Campylobacter pylori from the stomach because of acquired resistance during treatment. | 1990 | Am. J. Gastroenterol. | pmid:2153337 |
Chang AD et al. | Bacillary angiomatosis associated with extensive esophageal polyposis: a new mucocutaneous manifestation of acquired immunodeficiency disease (AIDS). | 1996 | Am. J. Gastroenterol. | pmid:8855753 |
Fiorucci S et al. | Effect of erythromycin on gastric and gallbladder emptying and gastrointestinal symptoms in scleroderma patients is maintained medium term. | 1994 | Am. J. Gastroenterol. | pmid:8147358 |
Rayner CK et al. | The stimulation of antral motility by erythromycin is attenuated by hyperglycemia. | 2000 | Am. J. Gastroenterol. | pmid:11007223 |
Bachman BA et al. | Erythromycin ethylsuccinate-induced cholestasis. | 1982 | Am. J. Gastroenterol. | pmid:6979924 |
Resnick J et al. | Delayed gastric emptying and postoperative ileus after nongastric abdominal surgery: part II. | 1997 | Am. J. Gastroenterol. | pmid:9177505 |
Camilleri M | The current role of erythromycin in the clinical management of gastric emptying disorders. | 1993 | Am. J. Gastroenterol. | pmid:8424415 |
Keshavarzian A and Isaac RM | Erythromycin accelerates gastric emptying of indigestible solids and transpyloric migration of the tip of an enteral feeding tube in fasting and fed states. | 1993 | Am. J. Gastroenterol. | pmid:8424419 |
Mantides A et al. | The effect of erythromycin in gastric emptying of solids and hypertonic liquids in healthy subjects. | 1993 | Am. J. Gastroenterol. | pmid:8424420 |
Richards RD et al. | The treatment of idiopathic and diabetic gastroparesis with acute intravenous and chronic oral erythromycin. | 1993 | Am. J. Gastroenterol. | pmid:8424421 |
Bonacini M et al. | Effect of intravenous erythromycin on postoperative ileus. | 1993 | Am. J. Gastroenterol. | pmid:8424422 |
Carmagnola S et al. | Mechanoreceptors of the proximal stomach and perception of gastric distension. | 2005 | Am. J. Gastroenterol. | pmid:16086705 |
Kalkay MN et al. | Campylobacter-induced toxic megacolon. | 1983 | Am. J. Gastroenterol. | pmid:6613968 |
Laine L and Jensen DM | Management of patients with ulcer bleeding. | 2012 | Am. J. Gastroenterol. | pmid:22310222 |