erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Walkey AJ and Wiener RS | Macrolide antibiotics and survival in patients with acute lung injury. | 2012 | Chest | pmid:22116799 |
Segatore B et al. | In vitro interaction of usnic acid in combination with antimicrobial agents against methicillin-resistant Staphylococcus aureus clinical isolates determined by FICI and ΔE model methods. | 2012 | Phytomedicine | pmid:22119041 |
De Francesco MA et al. | Phenotypes, genotypes, serotypes and molecular epidemiology of erythromycin-resistant Streptococcus agalactiae in Italy. | 2012 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:22120421 |
Weber JM et al. | An erythromycin process improvement using the diethyl methylmalonate-responsive (Dmr) phenotype of the Saccharopolyspora erythraea mutB strain. | 2012 | Appl. Microbiol. Biotechnol. | pmid:22048617 |
Dekio I | Follicular spicules associated with Propionibacterium acnes with response to erythromycin: Lack of evidence for the species? | 2012 | J. Dermatol. | pmid:22224953 |
Malnick SD and Melzer E | Compromise of patient safety in research report. | 2012 | J. Clin. Gastroenterol. | pmid:22227732 |
Moncrieffe MC et al. | Structure of the glycosyltransferase EryCIII in complex with its activating P450 homologue EryCII. | 2012 | J. Mol. Biol. | pmid:22056329 |
Popowska M et al. | Influence of soil use on prevalence of tetracycline, streptomycin, and erythromycin resistance and associated resistance genes. | 2012 | Antimicrob. Agents Chemother. | pmid:22203596 |
McCusker KP and Fujimori DG | The chemistry of peptidyltransferase center-targeted antibiotics: enzymatic resistance and approaches to countering resistance. | 2012 | ACS Chem. Biol. | pmid:22208312 |
Ducrotté P and Gourcerol G | [Gastroparesis: pathophysiology and management]. | 2012 | Presse Med | pmid:22154929 |
Biester EM et al. | Identification of avian wax synthases. | 2012 | BMC Biochem. | pmid:22305293 |
Jaglic Z et al. | Distribution, characterization and genetic bases of erythromycin resistance in staphylococci and enterococci originating from livestock. | 2012 | Zoonoses Public Health | pmid:21843202 |
Shiu WK et al. | Antibacterial acylphloroglucinols from Hypericum olympicum. | 2012 | J. Nat. Prod. | pmid:21899267 |
Boswihi SS et al. | Serotypes and antibiotic resistance in Group B streptococcus isolated from patients at the Maternity Hospital, Kuwait. | 2012 | J. Med. Microbiol. | pmid:21903822 |
Carbonero A et al. | Campylobacter spp., C. jejuni and C. upsaliensis infection-associated factors in healthy and ill dogs from clinics in Cordoba, Spain. Screening tests for antimicrobial susceptibility. | 2012 | Comp. Immunol. Microbiol. Infect. Dis. | pmid:22640550 |
Sadeghi SJ et al. | Drug-drug interactions and cooperative effects detected in electrochemically driven human cytochrome P450 3A4. | 2012 | Bioelectrochemistry | pmid:22480862 |
Nunoi H et al. | A relationship between motilin and growth hormone secretagogue receptors. | 2012 | Regul. Pept. | pmid:22465164 |
Jada S et al. | Design and synthesis of novel magnolol derivatives as potential antimicrobial and antiproliferative compounds. | 2012 | Eur J Med Chem | pmid:22424614 |
Saxena S et al. | Practical disk diffusion method for detection of inducible clindamycin resistance in Staphylococcus aureus at a tertiary care hospital: implications for clinical therapy. | 2012 | J Commun Dis | pmid:25151754 |
Bosnar M et al. | N'-substituted-2'-O,3'-N-carbonimidoyl bridged macrolides: novel anti-inflammatory macrolides without antimicrobial activity. | 2012 | J. Med. Chem. | pmid:22697905 |
Yiannakopoulou E et al. | Pharmacological modulation of oxidative stress response in minimally invasive surgery: systematic review. | 2012 | Surg Laparosc Endosc Percutan Tech | pmid:22678313 |
Bai J et al. | Erythromycin enhances CD4+Foxp3+ regulatory T-cell responses in a rat model of smoke-induced lung inflammation. | 2012 | Mediators Inflamm. | pmid:22701274 |
Vázquez-Sánchez D et al. | Incidence and characterization of Staphylococcus aureus in fishery products marketed in Galicia (Northwest Spain). | 2012 | Int. J. Food Microbiol. | pmid:22704064 |
Kim EY et al. | The effectiveness of erythromycin in reducing stent-related tissue hyperplasia: an experimental study with a rat esophageal model. | 2012 | Acta Radiol | pmid:22855416 |
Oldenburg M et al. | TLR13 recognizes bacterial 23S rRNA devoid of erythromycin resistance-forming modification. | 2012 | Science | pmid:22821982 |
Feng Z et al. | Unidirectional peristaltic movement in multisite drug binding pockets of AcrB from molecular dynamics simulations. | 2012 | Mol Biosyst | pmid:22825052 |
Maeda Y et al. | UV-C-irradiation sublethal stress does not alter antibiotic susceptibility of the viridans group streptococci to β-lactam, macrolide, and fluoroquinolone antibiotic agents. | 2012 | J Investig Clin Dent | pmid:22887906 |
Hossein nia R et al. | An expeditious regioselective synthesis of novel bioactive indole-substituted chromene derivatives via one-pot three-component reaction. | 2012 | Bioorg. Med. Chem. Lett. | pmid:22892120 |
Cetin M et al. | Clarithromycin-Induced Long QT Syndrome: A Case Report. | 2012 | Case Rep Med | pmid:22489247 |
Wauters J et al. | A Novel Method (CiMON) for Continuous Intra-Abdominal Pressure Monitoring: Pilot Test in a Pig Model. | 2012 | Crit Care Res Pract | pmid:22454765 |
Aiello A et al. | Aplisulfamines, new sulfoxide-containing metabolites from an aplidium tunicate: absolute stereochemistry at chiral sulfur and carbon atoms assigned through an original combination of spectroscopic and computational methods. | 2012 | Mar Drugs | pmid:22363220 |
Molnari JC and Myers AL | Carbonyl reduction of bupropion in human liver. | 2012 | Xenobiotica | pmid:22339467 |
Chiba Y et al. | Mechanism for folate-independent aldolase reaction catalyzed by serine hydroxymethyltransferase. | 2012 | FEBS J. | pmid:22141341 |
Lu X et al. | Antimicrobial effect of diallyl sulphide on Campylobacter jejuni biofilms. | 2012 | J. Antimicrob. Chemother. | pmid:22550133 |
Bistrian BR | The who, what, where, when, why, and how of early enteral feeding. | 2012 | Am. J. Clin. Nutr. | pmid:22552029 |
Noto MJ and Wheeler AP | Macrolides for acute lung injury. | 2012 | Chest | pmid:22553255 |
Milberg P et al. | Blockade of I(Ca) suppresses early afterdepolarizations and reduces transmural dispersion of repolarization in a whole heart model of chronic heart failure. | 2012 | Br. J. Pharmacol. | pmid:22013922 |
Chen X et al. | Synthesis and antibacterial activity of novel modified 5-O-desosamine ketolides. | 2012 | Bioorg. Med. Chem. Lett. | pmid:23122862 |
Klibi N et al. | Genotypic diversity, antibiotic resistance and bacteriocin production of enterococci isolated from rhizospheres. | 2012 | Microbes Environ. | pmid:23124764 |
Guan Y et al. | [Preliminary study of effects of andrographolide on Staphylococcus epidermidis biofilms]. | 2012 | Zhongguo Zhong Yao Za Zhi | pmid:23126203 |
Kelley C et al. | 3-Phenyl substituted 6,7-dimethoxyisoquinoline derivatives as FtsZ-targeting antibacterial agents. | 2012 | Bioorg. Med. Chem. | pmid:23127490 |
Parhi A et al. | Antibacterial activity of substituted 5-methylbenzo[c]phenanthridinium derivatives. | 2012 | Bioorg. Med. Chem. Lett. | pmid:23084900 |
Benet LZ | A step closer to personalized chemotherapy: consideration of the influence of genetic variation in hepatic uptake transporters on the metabolism of CYP3A substrates. | 2012 | Clin. Pharmacol. Ther. | pmid:23085879 |
Ocular prophylaxis for gonococcal ophthalmia neonatorum: reaffirmation recommendation statement. | 2012 | Am Fam Physician | pmid:22335221 | |
Jordan PA and Miller SJ | An approach to the site-selective deoxygenation of hydroxy groups based on catalytic phosphoramidite transfer. | 2012 | Angew. Chem. Int. Ed. Engl. | pmid:22319027 |
Lenglet A et al. | Surveillance status and recent data for Mycoplasma pneumoniae infections in the European Union and European Economic Area, January 2012. | 2012 | Euro Surveill. | pmid:22321134 |
Blystad H et al. | Increased incidence of Mycoplasma pneumoniae infection in Norway 2011. | 2012 | Euro Surveill. | pmid:22321136 |
Laine L and Jensen DM | Management of patients with ulcer bleeding. | 2012 | Am. J. Gastroenterol. | pmid:22310222 |
Waseem S et al. | Spectrum of gastroparesis in children. | 2012 | J. Pediatr. Gastroenterol. Nutr. | pmid:22314391 |
Koning S et al. | Interventions for impetigo. | 2012 | Cochrane Database Syst Rev | pmid:22258953 |