erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Airway Obstruction D000402 13 associated lipids
Tuberculosis D014376 20 associated lipids
Uremia D014511 33 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Nocardia Infections D009617 6 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Per page 10 20 50 100 | Total 442

PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Authors Title Published Journal PubMed Link
Schmitz FJ et al. In vitro activities of the ketolides ABT-773 and telithromycin and of three macrolides against genetically characterized isolates of Streptococcus pneumoniae, Streptococcus pyogenes, Haemophilus influenzae and Moraxella catarrhalis. 2002 J. Antimicrob. Chemother. pmid:12096026
Doneva M and Bineva I [Pharmacokinetic and microbiological studies of Pharmachem erythromycin asparate]. 1979 Vet Med Nauki pmid:120997
Cooper WO et al. Prenatal prescription of macrolide antibiotics and infantile hypertrophic pyloric stenosis. 2002 Obstet Gynecol pmid:12100810
Frossard JL et al. Erythromycin intravenous bolus infusion in acute upper gastrointestinal bleeding: a randomized, controlled, double-blind trial. 2002 Gastroenterology pmid:12105828
Jones A et al. Colistin stimulates the activity of neutrophil elastase and Pseudomonas aeruginosa elastase. 2002 Eur. Respir. J. pmid:12108869
Tagaya E et al. Effect of a short course of clarithromycin therapy on sputum production in patients with chronic airway hypersecretion. 2002 Chest pmid:12114361
Suzaki K Resistance of Mycoplasma pneumoniae to macrolide and analogous antibiotics. 1979 Sci Rep Res Inst Tohoku Univ Med pmid:121168
Iurenev PN et al. [Complications from antibiotic therapy]. 1975 Antibiotiki pmid:1211892
Belizhenko GG et al. [Study of the joint action of lysozyme and the antibiotics, tetracycline, erythromycin and levomycetin, on Staphylococcus aureus]. 1975 Antibiotiki pmid:1211905
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Berti MA and Maccari M Stability of frozen rat plasma containing different antibiotics. 1975 Antimicrob. Agents Chemother. pmid:1211917
Bennet R et al. The fecal microflora of 1-3-month-old infants during treatment with eight oral antibiotics. 2002 Infection pmid:12120942
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Clegg FG et al. Dry cow therapy: a comparative field trial using benzathine cloxacillin and erythromycin. 1975 Nov-Dec Br. Vet. J. pmid:1212603
Dutta GP and Singh PP Blood schizontocidal activity of some antibiotics against Plasmodium knowlesi infection in Assamese monkey. 1979 Indian J. Med. Res. pmid:121297
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Roger M Mismatch excision and possible polarity effects result in preferred deoxyribonucleic acid strand of integration in pneumococcal transformation. 1977 J. Bacteriol. pmid:12139
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de Zwart IM et al. Gastric motility: comparison of assessment with real-time MR imaging or barostat measurement initial experience. 2002 Radiology pmid:12147861
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Roddis M et al. Structural elucidation studies on 14- and 16-membered macrolide aglycones by accurate-mass electrospray sequential mass spectrometry. 2002 J. Am. Soc. Mass Spectrom. pmid:12148810
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García-Rey C et al. Pharmacoepidemiological analysis of provincial differences between consumption of macrolides and rates of erythromycin resistance among Streptococcus pyogenes isolates in Spain. 2002 J. Clin. Microbiol. pmid:12149359
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Mouly S et al. Hepatic but not intestinal CYP3A4 displays dose-dependent induction by efavirenz in humans. 2002 Clin. Pharmacol. Ther. pmid:12151999
Giovanetti E et al. Conjugative transfer of the erm(A) gene from erythromycin-resistant Streptococcus pyogenes to macrolide-susceptible S. pyogenes, Enterococcus faecalis and Listeria innocua. 2002 J. Antimicrob. Chemother. pmid:12161406
Tao L and Tanzer JM Novel sucrose-dependent adhesion co-factors in Streptococcus mutans. 2002 J. Dent. Res. pmid:12161466
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Banfield C et al. Lack of clinically relevant interaction between desloratadine and erythromycin. 2002 Clin Pharmacokinet pmid:12169044
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Lonks JR et al. Failure of macrolide antibiotic treatment in patients with bacteremia due to erythromycin-resistant Streptococcus pneumoniae. 2002 Clin. Infect. Dis. pmid:12173129
Petrakis IE et al. Hyperglycemia attenuates erythromycin-induced acceleration of solid-phase gastric emptying in healthy subjects. 2002 May-Jun Abdom Imaging pmid:12173362
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Liebl W et al. Plasmid-borne macrolide resistance in Micrococcus luteus. 2002 Microbiology (Reading, Engl.) pmid:12177341
Champney WS and Pelt J The ketolide antibiotic ABT-773 is a specific inhibitor of translation and 50S ribosomal subunit formation in Streptococcus pneumoniae cells. 2002 Curr. Microbiol. pmid:12177734
Steffen RM Effect of erythromycin on gastroduodenal contractile activity in developing neonates. 2002 Jul-Aug Clin Pediatr (Phila) pmid:12180432
Memis D et al. Effect of preoperative oral use of erythromycin and nizatidine on gastric pH and volume. 2002 Anaesth Intensive Care pmid:12180579
Netzer P et al. Effects of ABT-229, a motilin agonist, on acid reflux, oesophageal motility and gastric emptying in patients with gastro-oesophageal reflux disease. 2002 Aliment. Pharmacol. Ther. pmid:12182748
Athanasakis E et al. Octreotide enhances the accelerating effect of erythromycin on gastric emptying in healthy subjects. 2002 Aliment. Pharmacol. Ther. pmid:12182757
Leclercq R and Courvalin P Resistance to macrolides and related antibiotics in Streptococcus pneumoniae. 2002 Antimicrob. Agents Chemother. pmid:12183222
Ng LK et al. Mutation in 23S rRNA associated with macrolide resistance in Neisseria gonorrhoeae. 2002 Antimicrob. Agents Chemother. pmid:12183262
Prunier AL et al. Clinical isolates of Staphylococcus aureus with ribosomal mutations conferring resistance to macrolides. 2002 Antimicrob. Agents Chemother. pmid:12183270
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Thiele J et al. Dynamics of CD34+ progenitor cells following allogeneic bone marrow transplantation in Ph1+CML--an immunohistochemical study on 113 patients with sequential trephine biopsies. 2002 J. Hematother. Stem Cell Res. pmid:12183841
Raha AR et al. Characterisation and molecular cloning of an erythromycin resistance plasmid of Lactococcus lactis isolated from chicken cecum. 2002 J. Biochem. Mol. Biol. Biophys. pmid:12186776
Rönnblom A et al. Gastric emptying in myotonic dystrophy. 2002 Eur. J. Clin. Invest. pmid:12190956