erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Airway Obstruction D000402 13 associated lipids
Tuberculosis D014376 20 associated lipids
Uremia D014511 33 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Nocardia Infections D009617 6 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Per page 10 20 50 100 | Total 442

PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Authors Title Published Journal PubMed Link
Manzo L et al. [Effects of phenobarbital on the distribution of erythromycin and erythromycin aspartate in the rat]. 1976 Jan-Jun G Ital Chemioter pmid:1029694
Baggot JD and Gingerich DA Pharmacokinetic interpretation of erythromycin and tylosin activity in serum after intravenous administration of a single dose to cows. 1976 Res. Vet. Sci. pmid:1030820
Di Nucci A et al. [Metabolism of erythromycin and erythromycin aspartate in the microsomal fraction of the rat liver]. 1976 Boll. Soc. Ital. Biol. Sper. pmid:1030960
Fisher AA The safety of topical erythromycin. 1976 Contact Derm. pmid:1032121
van Ketel WG Immediate- and delayed-type allergy to erythromycin. 1976 Contact Derm. pmid:1032135
York MK et al. Characterization of antimicrobial resistance in Streptococcus pyogenes isolates from the San Francisco Bay area of northern California. 1999 J. Clin. Microbiol. pmid:10325315
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Dujovne CA Experimental investigations on the different hepatotoxic potential of erythromycin derivatives. 1976 Med Chir Dig pmid:1034861
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Fearfield LA and Staughton RC Severe vulval apocrine acne successfully treated with prednisolone and isotretinoin. 1999 Clin. Exp. Dermatol. pmid:10354177
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Petrakis IE et al. Hyperglycaemia attenuates erythromycin-induced acceleration of solid-phase gastric emptying in idiopathic and diabetic gastroparesis. 1999 Scand. J. Gastroenterol. pmid:10365900
Cilostazol for intermittent claudication. 1999 Med Lett Drugs Ther pmid:10368703
Gregory ST and Dahlberg AE Erythromycin resistance mutations in ribosomal proteins L22 and L4 perturb the higher order structure of 23 S ribosomal RNA. 1999 J. Mol. Biol. pmid:10369764
Arum ES and Jacobs NF Nongonococcal urethritis. 1976 Cutis pmid:1037101
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Hägg S et al. Absence of interaction between erythromycin and a single dose of clozapine. 1999 Eur. J. Clin. Pharmacol. pmid:10379638
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Feighner SD et al. Receptor for motilin identified in the human gastrointestinal system. 1999 Science pmid:10381885
Ruckdeschel G and Dalhoff A The in-vitro activity of moxifloxacin against Legionella species and the effects of medium on susceptibility test results. 1999 J. Antimicrob. Chemother. pmid:10382872
Nishijima T et al. Distribution of mefE and ermB genes in macrolide-resistant strains of Streptococcus pneumoniae and their variable susceptibility to various antibiotics. 1999 J. Antimicrob. Chemother. pmid:10382884
Bébéar CM et al. In-vitro activity of grepafloxacin, a new fluoroquinolone, against mycoplasmas. 1999 J. Antimicrob. Chemother. pmid:10382895
McConnell SA et al. Lack of effect of dirithromycin on theophylline pharmacokinetics in healthy volunteers. 1999 J. Antimicrob. Chemother. pmid:10382900
Tzelepi E et al. Erythromycin resistance amongst group A beta-haemolytic streptococci isolated in a paediatric hospital in Athens, Greece. 1999 J. Antimicrob. Chemother. pmid:10382903
Valisena S et al. Molecular typing of erythromycin-resistant streptococcus pyogenes strains with the M phenotype isolated in Italy. 1999 Eur. J. Clin. Microbiol. Infect. Dis. pmid:10385014
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