erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Airway Obstruction D000402 13 associated lipids
Tuberculosis D014376 20 associated lipids
Uremia D014511 33 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Nocardia Infections D009617 6 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Per page 10 20 50 100 | Total 442

PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Authors Title Published Journal PubMed Link
Chen C et al. Blocking the flow of propionate into TCA cycle through a mutB knockout leads to a significant increase of erythromycin production by an industrial strain of Saccharopolyspora erythraea. 2017 Bioprocess Biosyst Eng pmid:27709326
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Cluver C et al. Interventions for treating genital Chlamydia trachomatis infection in pregnancy. 2017 Cochrane Database Syst Rev pmid:28937705
Tran LTC et al. Erythromycin encapsulation in nanoemulsion-based delivery systems for treatment of Helicobacter pylori infection: Protection and synergy. 2017 Biochem. Biophys. Res. Commun. pmid:28917836
Gonser LI et al. Systemic therapy of ocular and cutaneous rosacea in children. 2017 J Eur Acad Dermatol Venereol pmid:28621909
Tintino SR et al. Tannic acid affects the phenotype of Staphylococcus aureus resistant to tetracycline and erythromycin by inhibition of efflux pumps. 2017 Bioorg. Chem. pmid:28841421
Ji W et al. Colonization prevalence and antibiotic susceptibility of Group B Streptococcus in pregnant women over a 6-year period in Dongguan, China. 2017 PLoS ONE pmid:28813477
Wang D et al. An analogous wood barrel theory to explain the occurrence of hormesis: A case study of sulfonamides and erythromycin on Escherichia coli growth. 2017 PLoS ONE pmid:28715457
Hawkins PA et al. Cross-resistance to lincosamides, streptogramins A and pleuromutilins in Streptococcus agalactiae isolates from the USA. 2017 J. Antimicrob. Chemother. pmid:28333320
Jia L et al. Synthesis and antibacterial evaluation of novel 11-O-carbamoyl clarithromycin ketolides. 2017 Bioorg. Med. Chem. Lett. pmid:28711353
Adhikari RP et al. Inducible clindamycin and methicillin resistant Staphylococcus aureus in a tertiary care hospital, Kathmandu, Nepal. 2017 BMC Infect. Dis. pmid:28693489
Wang HK et al. Clinical features and molecular characteristics of childhood community-associated methicillin-resistant Staphylococcus aureus infection in a medical center in northern Taiwan, 2012. 2017 BMC Infect. Dis. pmid:28679429
Haynes KM et al. Identification and Structure-Activity Relationships of Novel Compounds that Potentiate the Activities of Antibiotics in Escherichia coli. 2017 J. Med. Chem. pmid:28650638
Dalal A et al. Interventions for the prevention of recurrent erysipelas and cellulitis. 2017 Cochrane Database Syst Rev pmid:28631307
Štšepetova J et al. Assessment of phenotypic and genotypic antibiotic susceptibility of vaginal Lactobacillus sp. 2017 J. Appl. Microbiol. pmid:28574626
Tanaka Y et al. Applicability of ribosome engineering to vitamin B12 production by Propionibacterium shermanii. 2017 Biosci. Biotechnol. Biochem. pmid:28532245
Demczuk WHB et al. Phylogenetic analysis of emergent Streptococcus pneumoniae serotype 22F causing invasive pneumococcal disease using whole genome sequencing. 2017 PLoS ONE pmid:28531208
Cheled-Shoval S et al. From Cell to Beak: In-Vitro and In-Vivo Characterization of Chicken Bitter Taste Thresholds. 2017 Molecules pmid:28513558
Huang YW et al. Overexpression of SmeDEF Efflux Pump Decreases Aminoglycoside Resistance in Stenotrophomonas maltophilia. 2017 Antimicrob. Agents Chemother. pmid:28193669
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Giguère S Treatment of Infections Caused by Rhodococcus equi. 2017 Vet. Clin. North Am. Equine Pract. pmid:28161038
Wang Y et al. Evaluation of a series of 2-napthamide derivatives as inhibitors of the drug efflux pump AcrB for the reversal of antimicrobial resistance. 2017 Bioorg. Med. Chem. Lett. pmid:28129976
Descours G et al. Ribosomal Mutations Conferring Macrolide Resistance in Legionella pneumophila. 2017 Antimicrob. Agents Chemother. pmid:28069647
Owen L et al. A Multifactorial Comparison of Ternary Combinations of Essential Oils in Topical Preparations to Current Antibiotic Prescription Therapies for the Control of Acne Vulgaris-Associated Bacteria. 2017 Phytother Res pmid:28124400
Chen K et al. Drug-resistance dynamics of Staphylococcus aureus between 2008 and 2014 at a tertiary teaching hospital, Jiangxi Province, China. 2017 BMC Infect. Dis. pmid:28122513
Berni E et al. Risk of cardiovascular events, arrhythmia and all-cause mortality associated with clarithromycin versus alternative antibiotics prescribed for respiratory tract infections: a retrospective cohort study. 2017 BMJ Open pmid:28115334
Wei L et al. Transformation of erythromycin during secondary effluent soil aquifer recharging: Removal contribution and degradation path. 2017 J Environ Sci (China) pmid:28115128
Koryakina I et al. Inversion of Extender Unit Selectivity in the Erythromycin Polyketide Synthase by Acyltransferase Domain Engineering. 2017 ACS Chem. Biol. pmid:28103677
Sugimoto N et al. Invasive pneumococcal disease caused by mucoid serotype 3 Streptococcus pneumoniae: a case report and literature review. 2017 BMC Res Notes pmid:28057059
Liu J et al. Modulation of erythromycin-induced biochemical responses in crucian carp by ketoconazole. 2017 Environ Sci Pollut Res Int pmid:28004371
Hillitt KL et al. Antimicrobial activity of Manuka honey against antibiotic-resistant strains of the cell wall-free bacteria Ureaplasma parvum and Ureaplasma urealyticum. 2017 Lett. Appl. Microbiol. pmid:27992658
Kassem II et al. Antimicrobial-Resistant Campylobacter in Organically and Conventionally Raised Layer Chickens. 2017 Foodborne Pathog. Dis. pmid:27768387
Song KH et al. Characteristics of cefazolin inoculum effect-positive methicillin-susceptible staphylococcus aureus infection in a multicentre bacteraemia cohort. 2017 Eur. J. Clin. Microbiol. Infect. Dis. pmid:27714592
Kullin B et al. Toxin A-negative toxin B-positive ribotype 017 Clostridium difficile is the dominant strain type in patients with diarrhoea attending tuberculosis hospitals in Cape Town, South Africa. 2017 Eur. J. Clin. Microbiol. Infect. Dis. pmid:27696234
Pavlović D et al. Synthesis of novel 15-membered 8a-azahomoerythromycin A acylides: Consequences of structural modification at the C-3 and C-6 position on antibacterial activity. 2017 Eur J Med Chem pmid:27657812
Austin BA and Fleischer AB The extinction of topical erythromycin therapy for acne vulgaris and concern for the future of topical clindamycin. 2017 J Dermatolog Treat pmid:27425633
Jakubů V et al. Trends in the Minimum Inhibitory Concentrations of Erythromycin, Clarithromycin, Azithromycin, Ciprofloxacin, and Trimethoprim/Sulfamethoxazole for Strains of Bordetella pertussis isolated in the Czech Republic in 1967-2015. 2017 Cent. Eur. J. Public Health pmid:29346850
Romero L et al. Macrolides for treatment of Haemophilus ducreyi infection in sexually active adults. 2017 Cochrane Database Syst Rev pmid:29226307
Naimi HM et al. Determination of antimicrobial susceptibility patterns in Staphylococcus aureus strains recovered from patients at two main health facilities in Kabul, Afghanistan. 2017 BMC Infect. Dis. pmid:29187146
Ricker EB and Nuxoll E Synergistic effects of heat and antibiotics on Pseudomonas aeruginosa biofilms. 2017 Biofouling pmid:29039211
Bitew A et al. Species distribution and antibiotic susceptibility profile of bacterial uropathogens among patients complaining urinary tract infections. 2017 BMC Infect. Dis. pmid:28962545
Öksüz L and Gürler N [Serotype distribution and antibiotic resistance of Streptococcus pneumoniae strains isolated from the adult patients in a Turkish üniversity hospital]. 2017 Mikrobiyol Bul pmid:28929957
Svetlov MS et al. Kinetics of drug-ribosome interactions defines the cidality of macrolide antibiotics. 2017 Proc. Natl. Acad. Sci. U.S.A. pmid:29229833
Atkinson CT et al. Expression of acquired macrolide resistance genes in Haemophilus influenzae. 2017 J. Antimicrob. Chemother. pmid:28961896
Zhou Z et al. Combination of Erythromycin and Curcumin Alleviates Induced Osteomyelitis in Rats. 2017 Front Cell Infect Microbiol pmid:28884090
Michael-Kordatou I et al. On the capacity of ozonation to remove antimicrobial compounds, resistant bacteria and toxicity from urban wastewater effluents. 2017 J. Hazard. Mater. pmid:26947803
Wang B et al. Acid or erythromycin stress significantly improves transformation efficiency through regulating expression of DNA binding proteins in Lactococcus lactis F44. 2017 J. Dairy Sci. pmid:28987584
Quinn KL et al. Macrolides, Digoxin Toxicity and the Risk of Sudden Death: A Population-Based Study. 2017 Drug Saf pmid:28421551
Zhao L et al. Occurrence of erythromycin and its degradation products residues in honey. Validation of an analytical method. 2017 J Sep Sci pmid:28121061
Dreno B et al. Skin microbiome and acne vulgaris: Staphylococcus, a new actor in acne. 2017 Exp. Dermatol. pmid:28094874