| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Airway Obstruction | D000402 | 13 associated lipids |
| Tuberculosis | D014376 | 20 associated lipids |
| Uremia | D014511 | 33 associated lipids |
| Colitis, Ulcerative | D003093 | 24 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Nocardia Infections | D009617 | 6 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Hearing Loss, Sensorineural | D006319 | 8 associated lipids |
erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- J. Pharmacol. Exp. Ther. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kasetty G et al. | The Nonantibiotic Macrolide EM703 Improves Survival in a Model of Quinolone-Treated Pseudomonas aeruginosa Airway Infection. | 2017 | Antimicrob. Agents Chemother. | pmid:28652240 |
| Di Sante L et al. | pHTβ-promoted mobilization of non-conjugative resistance plasmids from Enterococcus faecium to Enterococcus faecalis. | 2017 | J. Antimicrob. Chemother. | pmid:28645197 |
| Ramos CJ and Antonetti DA | The role of small GTPases and EPAC-Rap signaling in the regulation of the blood-brain and blood-retinal barriers. | 2017 | Tissue Barriers | pmid:28632993 |
| Sader HS et al. | Antimicrobial Susceptibility Trends among Staphylococcus aureus Isolates from U.S. Hospitals: Results from 7 Years of the Ceftaroline (AWARE) Surveillance Program, 2010 to 2016. | 2017 | Antimicrob. Agents Chemother. | pmid:28630196 |
| Post A et al. | Antibiotic susceptibility profiles among Campylobacter isolates obtained from international travelers between 2007 and 2014. | 2017 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:28623550 |
| Ishikawa Y et al. | Inactivation kinetics and residual activity of CYP3A4 after treatment with erythromycin. | 2017 | Biopharm Drug Dispos | pmid:28425104 |
| Rea E and Husbands E | Erythromycin: prophylaxis against recurrent small bowel obstruction. | 2017 | BMJ Support Palliat Care | pmid:28356304 |
| Jia L et al. | Synthesis and antibacterial evaluation of novel 11-O-carbamoyl clarithromycin ketolides. | 2017 | Bioorg. Med. Chem. Lett. | pmid:28711353 |
| Adhikari RP et al. | Inducible clindamycin and methicillin resistant Staphylococcus aureus in a tertiary care hospital, Kathmandu, Nepal. | 2017 | BMC Infect. Dis. | pmid:28693489 |
| Wang HK et al. | Clinical features and molecular characteristics of childhood community-associated methicillin-resistant Staphylococcus aureus infection in a medical center in northern Taiwan, 2012. | 2017 | BMC Infect. Dis. | pmid:28679429 |
| Haynes KM et al. | Identification and Structure-Activity Relationships of Novel Compounds that Potentiate the Activities of Antibiotics in Escherichia coli. | 2017 | J. Med. Chem. | pmid:28650638 |
| Dalal A et al. | Interventions for the prevention of recurrent erysipelas and cellulitis. | 2017 | Cochrane Database Syst Rev | pmid:28631307 |
| Štšepetova J et al. | Assessment of phenotypic and genotypic antibiotic susceptibility of vaginal Lactobacillus sp. | 2017 | J. Appl. Microbiol. | pmid:28574626 |
| Tanaka Y et al. | Applicability of ribosome engineering to vitamin B12 production by Propionibacterium shermanii. | 2017 | Biosci. Biotechnol. Biochem. | pmid:28532245 |
| Calle-Miguel L et al. | [Resistance rates and phenotypic characterization of Streptococcus pyogenes in a paediatric population in Northern Spain (2005-2015)]. | 2017 | Rev Esp Quimioter | pmid:28233483 |
| Selwood DL | Macrocycles, the edge of drug-likeness chemical space or Goldilocks zone? | 2017 | Chem Biol Drug Des | pmid:28205398 |
| Shrivastav AM et al. | Highly sensitive and selective erythromycin nanosensor employing fiber optic SPR/ERY imprinted nanostructure: Application in milk and honey. | 2017 | Biosens Bioelectron | pmid:27825873 |
| Liu J et al. | Engineering of an Lrp family regulator SACE_Lrp improves erythromycin production in Saccharopolyspora erythraea. | 2017 | Metab. Eng. | pmid:27794466 |
| Marlow N et al. | The ORACLE Children Study: educational outcomes at 11 years of age following antenatal prescription of erythromycin or co-amoxiclav. | 2017 | Arch. Dis. Child. Fetal Neonatal Ed. | pmid:27515985 |
| Ksia S et al. | Molecular Characteristics of Erythromycin-Resistant Streptococcus pyogenes Strains Isolated from Children Patients in Tunis, Tunisia. | 2017 | Microb. Drug Resist. | pmid:27991848 |
| Olajuyigbe OO et al. | In vitro pharmacological interaction of caffeine and first-line antibiotics is antagonistic against clinically important bacterial pathogens. | 2017 | Acta Biochim. Pol. | pmid:28612062 |
| Pfaller MA et al. | Ceftaroline Activity Against Multidrug-Resistant Streptococcus pneumoniae from U.S. Medical Centers (2014) and Molecular Characterization of a Single Ceftaroline Nonsusceptible Isolate. | 2017 | Microb. Drug Resist. | pmid:27918694 |
| Chang KH et al. | Comparison of antibiotic regimens in preterm premature rupture of membranes: neonatal morbidity and 2-year follow-up of neurologic outcome. | 2017 | J. Matern. Fetal. Neonatal. Med. | pmid:27687157 |
| Weber JM et al. | Application of In Vitro Transposon Mutagenesis to Erythromycin Strain Improvement in Saccharopolyspora erythraea. | 2017 | Methods Mol. Biol. | pmid:27709581 |
| Tay JH et al. | Regiodivergent Glycosylations of 6-Deoxy-erythronolide B and Oleandomycin-Derived Macrolactones Enabled by Chiral Acid Catalysis. | 2017 | J. Am. Chem. Soc. | pmid:28627172 |
| Hong M et al. | C-assisted metabolomics analysis reveals the positive correlation between specific erythromycin production rate and intracellular propionyl-CoA pool size in Saccharopolyspora erythraea. | 2017 | Bioprocess Biosyst Eng | pmid:28567527 |
| Na HK et al. | Erythromycin infusion prior to endoscopy for acute nonvariceal upper gastrointestinal bleeding: a pilot randomized controlled trial. | 2017 | Korean J. Intern. Med. | pmid:28352063 |
| Li LH et al. | [Effect of low dose erythromycin on the proliferation of granulation tissue after tracheal injury]. | 2017 | Zhonghua Yi Xue Za Zhi | pmid:28316160 |
| Fohner AE et al. | PharmGKB summary: Macrolide antibiotic pathway, pharmacokinetics/pharmacodynamics. | 2017 | Pharmacogenet. Genomics | pmid:28146011 |
| Thomas L et al. | Ophthalmic Considerations in Stevens-Johnson Syndrome. | 2016 | J. Pediatr. | pmid:27318376 |
| Tang C et al. | The incidence and drug resistance of Clostridium difficile infection in Mainland China: a systematic review and meta-analysis. | 2016 | Sci Rep | pmid:27897206 |
| Sun H et al. | Mechanism Underlying Time-dependent Cross-phenomenon between Concentration-response Curves and Concentration Addition Curves: A Case Study of Sulfonamides-Erythromycin mixtures on Escherichia coli. | 2016 | Sci Rep | pmid:27644411 |
| Ulanovsky I et al. | Erythromycin Prophylaxis for Neonatal Conjunctivitis: Ointment Versus Drops. | 2016 | Isr. Med. Assoc. J. | pmid:28471562 |
| Tack J et al. | Motilin-induced gastric contractions signal hunger in man. | 2016 | Gut | pmid:25539673 |
| de Jesus Gaffney V et al. | Chemical and biochemical characterization and in vivo safety evaluation of pharmaceuticals in drinking water. | 2016 | Environ. Toxicol. Chem. | pmid:27061931 |
| Caumes E et al. | [Donovanosis (granuloma inguinale)]. | 2016 | Ann Dermatol Venereol | pmid:27773509 |
| Caumes E et al. | [Lymphogranuloma venereum]. | 2016 | Ann Dermatol Venereol | pmid:27773504 |
| Burr LD et al. | Macrolide Treatment Inhibits Pseudomonas aeruginosa Quorum Sensing in Non-Cystic Fibrosis Bronchiectasis. An Analysis from the Bronchiectasis and Low-Dose Erythromycin Study Trial. | 2016 | Ann Am Thorac Soc | pmid:27464029 |
| Ben Salem I et al. | Removal of Penicillin G and Erythromycin with Ionizing Radiation Followed by Biological Treatment. | 2016 | Curr. Microbiol. | pmid:27447798 |
| Hsieh PF et al. | The Klebsiella pneumoniae YfgL (BamB) lipoprotein contributes to outer membrane protein biogenesis, type-1 fimbriae expression, anti-phagocytosis, and in vivo virulence. | 2016 | Virulence | pmid:27029012 |
| Baker KR et al. | A High-Throughput Approach To Identify Compounds That Impair Envelope Integrity in Escherichia coli. | 2016 | Antimicrob. Agents Chemother. | pmid:27458225 |
| Juda M et al. | The prevalence of genotypes that determine resistance to macrolides, lincosamides, and streptogramins B compared with spiramycin susceptibility among erythromycin-resistant Staphylococcus epidermidis. | 2016 | Mem. Inst. Oswaldo Cruz | pmid:27008373 |
| Cui B et al. | Selection of suitable reference genes for gene expression studies in Staphylococcus capitis during growth under erythromycin stress. | 2016 | Mol. Genet. Genomics | pmid:27000656 |
| Pierattini EC et al. | Morpho-physiological response of Populus alba to erythromycin: A timeline of the health status of the plant. | 2016 | Sci. Total Environ. | pmid:27366984 |
| Bhadra PK et al. | Enhancement of the properties of a drug by mono-deuteriation: reduction of acid-catalysed formation of a gut-motilide enol ether from 8-deuterio-erythromycin B. | 2016 | Org. Biomol. Chem. | pmid:27273525 |
| Topp E et al. | Reduced persistence of the macrolide antibiotics erythromycin, clarithromycin and azithromycin in agricultural soil following several years of exposure in the field. | 2016 | Sci. Total Environ. | pmid:27096634 |
| Entorf M et al. | Comparative erythromycin and tylosin susceptibility testing of streptococci from bovine mastitis. | 2016 | Vet. Microbiol. | pmid:26732695 |
| Arenz S et al. | A combined cryo-EM and molecular dynamics approach reveals the mechanism of ErmBL-mediated translation arrest. | 2016 | Nat Commun | pmid:27380950 |
| Takahashi T et al. | Epidemiological study of erythromycin-resistant Streptococcus pyogenes from Korea and Japan by emm genotyping and multilocus sequence typing. | 2016 | Ann Lab Med | pmid:26522753 |
| Snoeys J et al. | Mechanistic understanding of the nonlinear pharmacokinetics and intersubject variability of simeprevir: A PBPK-guided drug development approach. | 2016 | Clin. Pharmacol. Ther. | pmid:26259716 |