Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Acquired Hyperostosis Syndrome D020083 1 associated lipids
Eisenmenger Complex D004541 1 associated lipids
Myelitis, Transverse D009188 1 associated lipids
Epiglottitis D004826 1 associated lipids
Tick Bites D064927 1 associated lipids
Focal Nodular Hyperplasia D020518 1 associated lipids
Furcation Defects D017823 1 associated lipids
Granulomatous Mastitis D058890 1 associated lipids
Syncope, Vasovagal D019462 1 associated lipids
Achondroplasia D000130 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

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Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Benson C Advances in the diagnosis and treatment of Mycobacterium avium complex (MAC) disease. 1994 AIDS Patient Care pmid:11362136
O'Day DM et al. Ocular pharmacokinetics of orally administered azithromycin in rabbits. 1994 J Ocul Pharmacol pmid:7714407
Klepser ME et al. Treatment of uncomplicated infections caused by Chlamydia trachomatis and Neisseria gonorrhoeae. 1994 Conn Med pmid:7924316
Wallace MR et al. Ototoxicity with azithromycin. 1994 Lancet pmid:7904701
Raszka WV et al. Multifocal M. intracellulare osteomyelitis in an immunocompetent child. 1994 Clin Pediatr (Phila) pmid:7813141
Spangler SK et al. Effect of CO2 on susceptibilities of anaerobes to erythromycin, azithromycin, clarithromycin, and roxithromycin. 1994 Antimicrob. Agents Chemother. pmid:8192445
Rehg J New potential therapies for cryptosporidiosis: an analysis of variables affecting drug efficacy. 1994 Folia Parasitol. pmid:8050751
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Handsfield HH et al. Multicenter trial of single-dose azithromycin vs. ceftriaxone in the treatment of uncomplicated gonorrhea. Azithromycin Gonorrhea Study Group. 1994 Mar-Apr Sex Transm Dis pmid:9071422
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Cheng B Advances in prevention and treatment of MAC. 1995 PI Perspect pmid:11363104
Debets-Ossenkopp YJ et al. Effect of an acidic environment on the susceptibility of Helicobacter pylori to trospectomycin and other antimicrobial agents. 1995 Eur. J. Clin. Microbiol. Infect. Dis. pmid:7649202
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Bermudez LE et al. Efficacy of azithromycin and rifabutin in preventing infection by Mycobacterium avium complex in beige mice. 1995 J. Antimicrob. Chemother. pmid:8591938
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Martin DH et al. Comparison of azithromycin and ceftriaxone for the treatment of chancroid. 1995 Clin. Infect. Dis. pmid:8562752
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Tajima T et al. [Pharmacokinetic and clinical studies with azithromycin (fine granule) in the pediatric field. Pediatric Study Group of Azithromycin]. 1995 Jpn J Antibiot pmid:7474329
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Sasaki J et al. [Comparative clinical study of azithromycin with tosufloxacin tosilate in the treatment of acute odontogenic infection]. 1995 Jpn J Antibiot pmid:7474331
Uchino U et al. [Effects of azithromycin on fecal flora of healthy adult volunteers]. 1995 Jpn J Antibiot pmid:7474332
Toscano MA et al. [Efficacy and tolerance of azithromycin in respiratory tract infections in children]. 1995 Minerva Pediatr. pmid:7476752
Scheen AJ [Pharma-clinics. Drug of the month. Azithromycin (Zitromax)]. 1995 Rev Med Liege pmid:7481274
al-Assi MT et al. Azithromycin triple therapy for Helicobacter pylori infection: azithromycin, tetracycline, and bismuth. 1995 Am. J. Gastroenterol. pmid:7872278
Andersen SL et al. Activity of azithromycin as a blood schizonticide against rodent and human plasmodia in vivo. 1995 Am. J. Trop. Med. Hyg. pmid:7872444
Schlossberg D Azithromycin and clarithromycin. 1995 Med. Clin. North Am. pmid:7791424
Weber JT and Johnson RE New treatments for Chlamydia trachomatis genital infection. 1995 Clin. Infect. Dis. pmid:7795110
Rizzato G et al. Efficacy of a three day course of azithromycin in moderately severe community-acquired pneumonia. 1995 Eur. Respir. J. pmid:7789484
Barry AL et al. Relative potencies of azithromycin, clarithromycin and five other orally administered antibiotics. 1995 J. Antimicrob. Chemother. pmid:7628991
Stamm WE et al. Azithromycin for empirical treatment of the nongonococcal urethritis syndrome in men. A randomized double-blind study. 1995 JAMA pmid:7629982
Schmid GP and Fontanarosa PB Evolving strategies for management of the nongonococcal urethritis syndrome. 1995 JAMA pmid:7629989
Sadiq ST et al. Effects of azithromycin on malariometric indices in The Gambia. 1995 Lancet pmid:7564674
Wawer MJ et al. AIDS intervention in Uganda. 1995 Science pmid:7570005
Amland PF et al. A prospective, double-blind, placebo-controlled trial of a single dose of azithromycin on postoperative wound infections in plastic surgery. 1995 Plast. Reconstr. Surg. pmid:7480237
Gastearena I et al. Determination of the alpha1-acid glycoprotein binding of azithromycin in vitro by equilibrium dialysis. 1995 J Chemother pmid:8904095
Domingo S et al. Significance of environmental conditions (pH and serum) on the in vitro potency of azithromycin against Brucella melitensis. 1995 J Chemother pmid:8904096