Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Airway Obstruction D000402 13 associated lipids
Stomach Ulcer D013276 75 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Otitis Media D010033 12 associated lipids
Carcinoma, Basal Cell D002280 6 associated lipids
Bacterial Infections D001424 21 associated lipids
Pain D010146 64 associated lipids
Per page 10 20 50 100 | Total 276

PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

Download all related citations
Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Stork CM et al. Elevated International Normalized Ratio associated with long-term azithromycin therapy in a child with cerebral palsy. 2011 Am J Health Syst Pharm pmid:21593229
Baker WL and Couch KA Azithromycin for the secondary prevention of coronary artery disease: a meta-analysis. 2007 Am J Health Syst Pharm pmid:17420199
Voytilla KL et al. Visual compatibility of azithromycin with 24 commonly used drugs during simulated Y-site delivery. 2002 Am J Health Syst Pharm pmid:12004465
Goldstein RC et al. Fluoroquinolone- and ceftriaxone-based therapy of community-acquired pneumonia in hospitalized patients: the risk of subsequent isolation of multidrug-resistant organisms. 2014 Am J Infect Control pmid:24773792
Sorvillo F et al. Incidence and determinants of Pseudomonas aeruginosa infection among persons with HIV: association with hospital exposure. 2001 Am J Infect Control pmid:11287873
Lilley LL and Guanci R Distraction delays a dose. 1998 Am J Nurs pmid:9473978
Hashisaki GT Update on macrolide antibiotics. 1995 May-Jun Am J Otolaryngol pmid:7661309
Marple BF et al. Azithromycin extended release vs amoxicillin/clavulanate: symptom resolution in acute sinusitis. 2010 Jan-Feb Am J Otolaryngol pmid:19944891
El Hennawi DED et al. Management of recurrent tonsillitis in children. Am J Otolaryngol pmid:28385329
Klapan I et al. Azithromycin versus amoxicillin/clavulanate in the treatment of acute sinusitis. 1999 Jan-Feb Am J Otolaryngol pmid:9950107
Mvundura E et al. Good pregnancy outcome with emergent cerclage placed in the presence of intra-amniotic microbial invasion. 2007 Am J Perinatol pmid:17597442
Crum NF et al. Halting a pneumococcal pneumonia outbreak among United States Marine Corps trainees. 2003 Am J Prev Med pmid:12880877
Wolter JM et al. Macrolides in cystic fibrosis: is there a role? 2002 Am J Respir Med pmid:14720043
Margaritis VK et al. Sinus fluid penetration of oral clarithromycin and azithromycin in patients with acute rhinosinusitis. 2007 Sep-Oct Am J Rhinol pmid:17999793
Maniakas A and Desrosiers M Azithromycin add-on therapy in high-risk postendoscopic sinus surgery patients failing corticosteroid irrigations: A clinical practice audit. Am J Rhinol Allergy pmid:24598145
Amali A et al. Long-term postoperative azithromycin in patients with chronic rhinosinusitis: A randomized clinical trial. Am J Rhinol Allergy pmid:26637580
Bin Abdulhak AA et al. Azithromycin and Risk of Cardiovascular Death: A Meta-Analytic Review of Observational Studies. Am J Ther pmid:25748818
Sutera L et al. Azithromycin in an older woman with diabetic gastroparesis. 2008 Jan-Feb Am J Ther pmid:18223358
Muhlestein JB Animal models of chlamydia and atherosclerosis. 1999 Am. Heart J. pmid:10539862
Gupta S Chlamydia pneumoniae, monocyte activation, and azithromycin in coronary heart disease. 1999 Am. Heart J. pmid:10539869