Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Amsden G et al. | Lack of an effect of azithromycin on the disposition of zidovudine and dideoxyinosine in HIV-infected patients. | 2001 | J Clin Pharmacol | pmid:11210404 |
| Mizen L | The activity of antibiotics against Legionella pneumophila: in vitro and in vivo studies. | 2001 | J. Antimicrob. Chemother. | pmid:11222573 |
| Amsden GW and Gray CL | Serum and WBC pharmacokinetics of 1500 mg of azithromycin when given either as a single dose or over a 3 day period in healthy volunteers. | 2001 | J. Antimicrob. Chemother. | pmid:11152432 |
| Giacometti A et al. | Activity of buforin II alone and in combination with azithromycin and minocycline against Cryptosporidium parvum in cell culture. | 2001 | J. Antimicrob. Chemother. | pmid:11152438 |
| Page RL et al. | Possible interaction between intravenous azithromycin and oral cyclosporine. | 2001 | Pharmacotherapy | pmid:11714218 |
| Amsden GW | Advanced-generation macrolides: tissue-directed antibiotics. | 2001 | Int. J. Antimicrob. Agents | pmid:11574189 |
| Malizia T et al. | Interaction between piroxicam and azithromycin during distribution to human periodontal tissues. | 2001 | J. Periodontol. | pmid:11577945 |
| Salopek-Rabatić J | Chlamydial conjunctivitis in contact lens wearers: successful treatment with single dose azithromycin. | 2001 | CLAO J | pmid:11725983 |
| Butler T | Effect of increased inoculum of Salmonella typhi on MIC of azithromycin and resultant growth characteristics. | 2001 | J. Antimicrob. Chemother. | pmid:11733476 |
| Calvo A et al. | [Activity of different antimicrobial agents against penicillin-resistant Streptococcus pneumoniae]. | 2001 | Rev Esp Quimioter | pmid:11856980 |
| Kastner U and Guggenbichler JP | Influence of macrolide antibiotics on promotion of resistance in the oral flora of children. | 2001 | Infection | pmid:11688901 |
| Treadway G | Azithromycin: a new 15-membered macrolide. | 2001 | Jpn J Antibiot | pmid:11296412 |
| Hafner R et al. | Tolerance and pharmacokinetic interactions of rifabutin and azithromycin. | 2001 | Antimicrob. Agents Chemother. | pmid:11302832 |
| Chetchotisakd P et al. | Maintenance therapy of melioidosis with ciprofloxacin plus azithromycin compared with cotrimoxazole plus doxycycline. | 2001 Jan-Feb | Am. J. Trop. Med. Hyg. | pmid:11425157 |
| Baumann U et al. | Buccal adherence of Pseudomonas aeruginosa in patients with cystic fibrosis under long-term therapy with azithromycin. | 2001 Jan-Feb | Infection | pmid:11261763 |
| Kent JR et al. | Azithromycin: an assessment of its pharmacokinetics and therapeutic potential in CAPD. | 2001 Jul-Aug | Perit Dial Int | pmid:11587400 |
| Gakiya E et al. | [Experimental infection in mice by Plasmodium berghei: an evidence of antiparasitic action of azithromycin]. | 2001 Mar-Apr | Rev. Soc. Bras. Med. Trop. | pmid:11391444 |
| Lorenz J et al. | Treatment outcomes in acute exacerbations of chronic bronchitis: comparison of macrolides and moxifloxacin from the patient perspective. | 2001 Mar-Apr | J. Int. Med. Res. | pmid:11393351 |
| Postma MJ et al. | Cost-effectiveness of partner pharmacotherapy in screening women for asymptomatic infection with Chlamydia Trachomatis. | 2001 May-Jun | Value Health | pmid:11705188 |
| Akritopoulou-Zanze I and Sowin TJ | Solid-phase synthesis of macrolide analogues. | 2001 May-Jun | J Comb Chem | pmid:11350254 |
| Aberg JA et al. | Presence of macrolide resistance in respiratory flora of HIV-Infected patients receiving either clarithromycin or azithromycin for Mycobacterium avium complex prophylaxis. | 2001 Nov-Dec | HIV Clin Trials | pmid:11742432 |
| Biswas S | In-vitro antimalarial activity of azithromycin against chloroquine sensitive and chloroquine resistant Plasmodium falciparum. | 2001 Oct-Dec | J Postgrad Med | pmid:11832638 |
| Pukrittayakamee S et al. | Therapeutic responses to antibacterial drugs in vivax malaria. | 2001 Sep-Oct | Trans. R. Soc. Trop. Med. Hyg. | pmid:11706666 |
| Schilling F and Kessler S | [Chronic recurrent multifocal osteomyelitis-- I. Review]. | 2001 Sep-Oct | Klin Padiatr | pmid:11582525 |
| Schilling F et al. | [Pelvic type of chronic recurrent multifocal osteomyelitis]. | 2001 Sep-Oct | Klin Padiatr | pmid:11582526 |
| Dubois J and St-Pierre C | In vitro susceptibility study of BMS-284756 against Legionella species. | 2001 Sep-Oct | Diagn. Microbiol. Infect. Dis. | pmid:11687318 |
| [Azithromycin for pediatric indications. Brief therapy is ideal for children]. | 2002 | MMW Fortschr Med | pmid:12532527 | |
| Dakdouki GK et al. | Azithromycin-induced rash in infectious mononucleosis. | 2002 | Scand. J. Infect. Dis. | pmid:12587634 |
| Esteban J et al. | A comparison between disk diffusion and microdilution for susceptibility testing of Mycobacterium fortuitum complex. | 2002 | J Chemother | pmid:12583544 |
| Williams K | Patient-delivered therapy: an additional means for addressing the Chlamydia trachomatis problem. | 2002 | Tenn Med | pmid:12491815 |
| Ranque S et al. | Triangular test applied to the clinical trial of azithromycin against relapses in Plasmodium vivax infections. | 2002 | Malar. J. | pmid:12473182 |
| Allam AF and Shehab AY | Efficacy of azithromycin, praziquantel and mirazid in treatment of cryptosporidiosis in school children. | 2002 | J Egypt Soc Parasitol | pmid:12512828 |
| Hook EW et al. | A randomized, comparative pilot study of azithromycin versus benzathine penicillin G for treatment of early syphilis. | 2002 | Sex Transm Dis | pmid:12172535 |
| Ohrt C et al. | Assessment of azithromycin in combination with other antimalarial drugs against Plasmodium falciparum in vitro. | 2002 | Antimicrob. Agents Chemother. | pmid:12121927 |
| Gandhi R et al. | Characterization of azithromycin hydrates. | 2002 | Eur J Pharm Sci | pmid:12128172 |
| Fulcher SF et al. | Delayed-onset mycobacterial keratitis after LASIK. | 2002 | Cornea | pmid:12131028 |
| Gaynor BD et al. | Rationale for mass antibiotic distribution for trachoma elimination. | 2002 | Int Ophthalmol Clin | pmid:12189619 |
| Fry AM et al. | Adverse and beneficial secondary effects of mass treatment with azithromycin to eliminate blindness due to trachoma in Nepal. | 2002 | Clin. Infect. Dis. | pmid:12145722 |
| Shelby-James TM et al. | Impact of single dose azithromycin on group A streptococci in the upper respiratory tract and skin of Aboriginal children. | 2002 | Pediatr. Infect. Dis. J. | pmid:12150171 |
| Blondeau JM | The evolution and role of macrolides in infectious diseases. | 2002 | Expert Opin Pharmacother | pmid:12150692 |
| Khan WA et al. | Comparison of single-dose azithromycin and 12-dose, 3-day erythromycin for childhood cholera: a randomised, double-blind trial. | 2002 | Lancet | pmid:12480424 |
| Weiss LM | Babesiosis in humans: a treatment review. | 2002 | Expert Opin Pharmacother | pmid:12150690 |
| Rao RU et al. | Brugia malayi: effects of antibacterial agents on larval viability and development in vitro. | 2002 | Exp. Parasitol. | pmid:12243742 |
| Pastor E et al. | [Macrolide consumption according to geographic areas in the province of Valladolid]. | 2002 | Enferm. Infecc. Microbiol. Clin. | pmid:12433351 |
| Matute AJ et al. | Double-blind, placebo-controlled study comparing the effect of azithromycin with clarithromycin on oropharyngeal and bowel microflora in volunteers. | 2002 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:12111597 |
| Williams ES and Miller JM | Results from late-breaking clinical trial sessions at the American College of Cardiology 51st Annual Scientific Session. | 2002 | J. Am. Coll. Cardiol. | pmid:12113263 |
| Kopjar B | Azithromycin is effective in patients with chronic bronchitis. | 2002 | J. Antimicrob. Chemother. | pmid:12205072 |
| Baschiera F et al. | Improved tonsillar disposition of azithromycin following a 3-day oral treatment with 20 mg kg(-1) in paediatric patients. | 2002 | Pharmacol. Res. | pmid:12208127 |
| Maizumi N et al. | Quantitative comparison of the cytocidal effect of seven macrolide antibiotics on human periodontal ligament fibroblasts. | 2002 | J. Periodont. Res. | pmid:12200967 |
| House D et al. | Cytokine release by lipopolysaccharide-stimulated whole blood from patients with typhoid fever. | 2002 | J. Infect. Dis. | pmid:12134261 |
| Paladino JA et al. | Cost-effectiveness of IV-to-oral switch therapy: azithromycin vs cefuroxime with or without erythromycin for the treatment of community-acquired pneumonia. | 2002 | Chest | pmid:12377852 |
| Kutlin A et al. | Effect of gemifloxacin on viability of Chlamydia pneumoniae (Chlamydophila pneumoniae) in an in vitro continuous infection model. | 2002 | J. Antimicrob. Chemother. | pmid:12003969 |
| Rustomjee R et al. | A randomized controlled trial of azithromycin versus doxycycline/ciprofloxacin for the syndromic management of sexually transmitted infections in a resource-poor setting. | 2002 | J. Antimicrob. Chemother. | pmid:12003988 |
| Voytilla KL et al. | Visual compatibility of azithromycin with 24 commonly used drugs during simulated Y-site delivery. | 2002 | Am J Health Syst Pharm | pmid:12004465 |
| Amsden GW et al. | A study of the interaction potential of azithromycin and clarithromycin with atorvastatin in healthy volunteers. | 2002 | J Clin Pharmacol | pmid:11936570 |
| Lacroix JS et al. | Symptoms and clinical and radiological signs predicting the presence of pathogenic bacteria in acute rhinosinusitis. | 2002 | Acta Otolaryngol. | pmid:11936912 |
| Ghaffar F et al. | Effects of large dosages of amoxicillin/clavulanate or azithromycin on nasopharyngeal carriage of Streptococcus pneumoniae, Haemophilus influenzae, nonpneumococcal alpha-hemolytic streptococci, and Staphylococcus aureus in children with acute otitis media. | 2002 | Clin. Infect. Dis. | pmid:11981724 |
| Edelstein PH | Predicting the emergence of antimicrobial resistance. | 2002 | Clin. Infect. Dis. | pmid:11981741 |
| Bosch-Driessen LH et al. | A prospective, randomized trial of pyrimethamine and azithromycin vs pyrimethamine and sulfadiazine for the treatment of ocular toxoplasmosis. | 2002 | Am. J. Ophthalmol. | pmid:12095805 |
| Champney WS and Miller M | Inhibition of 50S ribosomal subunit assembly in Haemophilus influenzae cells by azithromycin and erythromycin. | 2002 | Curr. Microbiol. | pmid:12000992 |
| Butler T | Reduction of MIC of azithromycin for Salmonella typhi and Staphylococcus aureus in broth exposed to previous growth of Salmonella typhi. | 2002 | J. Antimicrob. Chemother. | pmid:12096025 |
| White RL et al. | Comparative activity of gatifloxacin and other antibiotics against 4009 clinical isolates of Streptococcus pneumoniae in the United States during 1999-2000. | 2002 | Diagn. Microbiol. Infect. Dis. | pmid:12106954 |
| Cohen R et al. | Comparison of two dosages of azithromycin for three days versus penicillin V for ten days in acute group A streptococcal tonsillopharyngitis. | 2002 | Pediatr. Infect. Dis. J. | pmid:12075760 |
| Schaad UB et al. | Azithromycin versus penicillin V for treatment of acute group A streptococcal pharyngitis. | 2002 | Pediatr. Infect. Dis. J. | pmid:12075761 |
| Domeika M et al. | Chlamydia trachomatis infections in eastern Europe: legal aspects, epidemiology, diagnosis, and treatment. | 2002 | Sex Transm Infect | pmid:12081171 |
| Patrick DM et al. | Heterosexual outbreak of infectious syphilis: epidemiological and ethnographic analysis and implications for control. | 2002 | Sex Transm Infect | pmid:12083438 |
| Campos-Outcalt D et al. | Use of directly observed azithromycin treatment for syphilis in a homeless woman. | 2002 | Sex Transm Dis | pmid:12035029 |
| Lisby JG et al. | [Bacteremia and meningitis caused by Streptococcus pneumoniae during treatment with azithromycin]. | 2002 | Ugeskr. Laeg. | pmid:12043408 |
| Jung R et al. | Intracellular activity of ABT-773 and other antimicrobial agents against Legionella pneumophila. | 2002 | J. Antimicrob. Chemother. | pmid:12003984 |
| Gaylor AS and Reilly JC | Therapy with macrolides in patients with cystic fibrosis. | 2002 | Pharmacotherapy | pmid:11837560 |
| Ohara T et al. | Effects of azithromycin on shiga toxin production by Escherichia coli and subsequent host inflammatory response. | 2002 | Antimicrob. Agents Chemother. | pmid:12384353 |
| Sullivan B et al. | Comparison of azithromycin and clarithromycin in triple therapy regimens for the eradication of Helicobacter pylori. | 2002 | Am. J. Gastroenterol. | pmid:12385435 |
| Brook I | Antibacterial therapy for acute group a streptococcal pharyngotonsillitis: short-course versus traditional 10-day oral regimens. | 2002 | Paediatr Drugs | pmid:12390046 |
| Tambiah J and Powell JT | Chlamydia pneumoniae antigens facilitate experimental aortic dilatation: prevention with azithromycin. | 2002 | J. Vasc. Surg. | pmid:12422113 |
| Arnez M et al. | Solitary erythema migrans in children: comparison of treatment with azithromycin and phenoxymethylpenicillin. | 2002 | Wien. Klin. Wochenschr. | pmid:12422590 |
| Maraspin V et al. | Development of erythema migrans in spite of treatment with antibiotics after a tick bite. | 2002 | Wien. Klin. Wochenschr. | pmid:12422612 |
| Hall IH et al. | Disposition and intracellular activity of azithromycin in human THP-1 acute monocytes. | 2002 | Int. J. Antimicrob. Agents | pmid:12431870 |
| Wolter JM et al. | Macrolides in cystic fibrosis: is there a role? | 2002 | Am J Respir Med | pmid:14720043 |
| Stone AF et al. | Effect of treatment for Chlamydia pneumoniae and Helicobacter pylori on markers of inflammation and cardiac events in patients with acute coronary syndromes: South Thames Trial of Antibiotics in Myocardial Infarction and Unstable Angina (STAMINA). | 2002 | Circulation | pmid:12208796 |
| Sirois F | [Delirium associated with azithromycin administration]. | 2002 | Can J Psychiatry | pmid:12211892 |
| Fraser-Hurt N and Mabey D | Trachoma. | 2002 | Clin Evid | pmid:12230687 |
| Frank E et al. | A multicenter, open-label, randomized comparison of levofloxacin and azithromycin plus ceftriaxone in hospitalized adults with moderate to severe community-acquired pneumonia. | 2002 | Clin Ther | pmid:12240780 |
| Shor A | Atherosclerosis: lipid infiltration or Chlamydia pneumoniae infection? | 2002 | Circulation | pmid:12403680 |
| Orfila J et al. | [Systematic screening for Chlamydia trachomatis with the molecular biological AMP-CT test in urine samples from young women]. | 2002 | J Gynecol Obstet Biol Reprod (Paris) | pmid:12407326 |
| Krolewiecki A et al. | Activity of azithromycin against Leishmania major in vitro and in vivo. | 2002 | Am. J. Trop. Med. Hyg. | pmid:12408666 |
| Ortega E et al. | In vitro and ex vivo effects of erythromycin A, azithromycin and josamycin on the splenic response to specific antigens and mitogens. | 2002 | J. Antimicrob. Chemother. | pmid:12039899 |
| Steinberg JM and Srugo I | Reoccurrence of culture-positive pertussis in an infant initially treated with azithromycin and steroids. | 2002 | Arch Pediatr Adolesc Med | pmid:12361458 |
| Hauben M and Amsden GW | The association of erythromycin and infantile hypertrophic pyloric stenosis: causal or coincidental? | 2002 | Drug Saf | pmid:12381214 |
| Vorbach H et al. | Endothelial cell compatibility of azithromycin and erythromycin. | 2002 | J. Antimicrob. Chemother. | pmid:11815590 |
| Kim MK et al. | Bactericidal effect and pharmacodynamics of cethromycin (ABT-773) in a murine pneumococcal pneumonia model. | 2002 | Antimicrob. Agents Chemother. | pmid:12234843 |
| Milberg P et al. | Divergent proarrhythmic potential of macrolide antibiotics despite similar QT prolongation: fast phase 3 repolarization prevents early afterdepolarizations and torsade de pointes. | 2002 | J. Pharmacol. Exp. Ther. | pmid:12235254 |
| Cascio A and Colomba C | [Macrolides in the treatment of children with Mediterranean spotted fever]. | 2002 | Infez Med | pmid:12704264 |
| Parchure N et al. | Effect of azithromycin treatment on endothelial function in patients with coronary artery disease and evidence of Chlamydia pneumoniae infection. | 2002 | Circulation | pmid:11901039 |
| SoRelle R | Treatment with azithromycin improves endothelial function. | 2002 | Circulation | pmid:11902195 |
| Firsov AA et al. | Comparative pharmacodynamics of azithromycin and roxithromycin with S. pyogenes and S. pneumoniae in a model that simulates in vitro pharmacokinetics in human tonsils. | 2002 | J. Antimicrob. Chemother. | pmid:11751774 |
| Corbu C et al. | [Ocular toxoplasmosis and consecutive complicated cataract]. | 2002 | Oftalmologia | pmid:12677800 |
| Cascio A et al. | Clarithromycin versus azithromycin in the treatment of Mediterranean spotted fever in children: a randomized controlled trial. | 2002 | Clin. Infect. Dis. | pmid:11740701 |
| Rapp RP | Clinical and economic outcomes in respiratory tract infections: The impact of bacterial resistance. | 2002 | Postgrad Med | pmid:19667590 |
| Lau CY and Qureshi AK | Azithromycin versus doxycycline for genital chlamydial infections: a meta-analysis of randomized clinical trials. | 2002 | Sex Transm Dis | pmid:12218839 |
| Culić O et al. | Azithromycin modulates neutrophil function and circulating inflammatory mediators in healthy human subjects. | 2002 | Eur. J. Pharmacol. | pmid:12208321 |