Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Agarwal P et al. | susceptibility of Indian isolates to different antimalarial drugs & antibiotics. | 2017 | Indian J. Med. Res. | pmid:29512604 |
| Hoogewoud F et al. | Prognostic Factors in Syphilitic Uveitis. | 2017 | Ophthalmology | pmid:28779905 |
| Bloch EM et al. | Antibiotic Resistance in Young Children in Kilosa District, Tanzania 4 Years after Mass Distribution of Azithromycin for Trachoma Control. | 2017 | Am. J. Trop. Med. Hyg. | pmid:28722638 |
| O'Brien KS et al. | Mass Azithromycin and Malaria Parasitemia in Niger: Results from a Community-Randomized Trial. | 2017 | Am. J. Trop. Med. Hyg. | pmid:28722569 |
| Stoney RJ et al. | Travelers' Diarrhea and Other Gastrointestinal Symptoms Among Boston-Area International Travelers. | 2017 | Am. J. Trop. Med. Hyg. | pmid:28719282 |
| Harper LM et al. | Economic Evaluation of Adjunctive Azithromycin Prophylaxis for Cesarean Delivery. | 2017 | Obstet Gynecol | pmid:28697108 |
| Fan LC et al. | Macrolides protect against infection via inhibition of inflammasomes. | 2017 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:28684545 |
| Emmanuel R et al. | Antimicrobial efficacy of drug blended biosynthesized colloidal gold nanoparticles from Justicia glauca against oral pathogens: A nanoantibiotic approach. | 2017 | Microb. Pathog. | pmid:29101061 |
| Riddle MS et al. | Trial Evaluating Ambulatory Therapy of Travelers' Diarrhea (TrEAT TD) Study: A Randomized Controlled Trial Comparing 3 Single-Dose Antibiotic Regimens With Loperamide. | 2017 | Clin. Infect. Dis. | pmid:29029033 |
| Alchakaki A et al. | Which patients with respiratory disease need long-term azithromycin? | 2017 | Cleve Clin J Med | pmid:28985171 |
| Senilă S et al. | Infliximab-induced acne and acute localized exanthematous pustulosis: Case report. | 2017 | Dermatol Ther | pmid:28976720 |
| Giguère S et al. | Antimicrobial Resistance in . | 2017 | Microbiol Spectr | pmid:29052538 |
| Boggess KA et al. | Risk Factors for Postcesarean Maternal Infection in a Trial of Extended-Spectrum Antibiotic Prophylaxis. | 2017 | Obstet Gynecol | pmid:28178058 |
| Ullah S et al. | Creatinine-based non-phospholipid vesicular carrier for improved oral bioavailability of Azithromycin. | 2017 | Drug Dev Ind Pharm | pmid:28157445 |
| Mohammed H et al. | First line dual therapy for gonorrhoea to limit the spread of antimicrobial resistance. | 2017 | BMJ | pmid:28153820 |
| Oluwalana C et al. | Azithromycin in Labor Lowers Clinical Infections in Mothers and Newborns: A Double-Blind Trial. | 2017 | Pediatrics | pmid:28130432 |
| Gerber JS and Zaoutis TE | Azithromycin Prophylaxis for Laboring Mothers. | 2017 | Pediatrics | pmid:28130431 |
| Cogen JD et al. | Characterization of Inpatient Cystic Fibrosis Pulmonary Exacerbations. | 2017 | Pediatrics | pmid:28126911 |
| Varano GP et al. | Post-ischemic treatment with azithromycin protects ganglion cells against retinal ischemia/reperfusion injury in the rat. | 2017 | Mol. Vis. | pmid:29296071 |
| White AC | Treatment of Early Syphilis in HIV: What Do We Really Know? | 2017 | Clin. Infect. Dis. | pmid:28362951 |
| Sharpton R et al. | Do cystic fibrosis patients on azithromycin need electrocardiogram monitoring? | 2017 | Pulm Pharmacol Ther | pmid:28219728 |
| Braam JF et al. | High prevalence of the A2058T macrolide resistance-associated mutation in Mycoplasma genitalium strains from the Netherlands. | 2017 | J. Antimicrob. Chemother. | pmid:28158595 |
| Gensel JC et al. | Predictive screening of M1 and M2 macrophages reveals the immunomodulatory effectiveness of post spinal cord injury azithromycin treatment. | 2017 | Sci Rep | pmid:28057928 |
| Sutton SS | Is cardiovascular risk a concern when prescribing azithromycin? | 2017 | JAAPA | pmid:28033168 |
| Shapiro ED and Wormser GP | Prophylaxis with topical azithromycin against Lyme borreliosis. | 2017 | Lancet Infect Dis | pmid:28007427 |
| Babić I et al. | Therapeutic efficacy of azithromycin and acetylcysteine in chronic otitis media with effusion. | 2017 | Eur Arch Otorhinolaryngol | pmid:27873023 |
| Seyama S et al. | Emergence and molecular characterization of Haemophilus influenzae harbouring mef(A). | 2017 | J. Antimicrob. Chemother. | pmid:27999037 |
| Demczuk W et al. | Neisseria gonorrhoeae Sequence Typing for Antimicrobial Resistance, a Novel Antimicrobial Resistance Multilocus Typing Scheme for Tracking Global Dissemination of N. gonorrhoeae Strains. | 2017 | J. Clin. Microbiol. | pmid:28228492 |
| Yan M et al. | Synthesis and antibacterial activity of novel 3-O-descladinosylazithromycin derivatives. | 2017 | Eur J Med Chem | pmid:27836198 |
| Ginouvès M et al. | In Vitro Sensitivity of Cutaneous Leishmania Promastigote Isolates Circulating in French Guiana to a Set of Drugs. | 2017 | Am. J. Trop. Med. Hyg. | pmid:28167598 |
| Haque F et al. | Evaluation of a Smartphone Decision-Support Tool for Diarrheal Disease Management in a Resource-Limited Setting. | 2017 | PLoS Negl Trop Dis | pmid:28103233 |
| Bulman ZP et al. | Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin. | 2017 | Antimicrob. Agents Chemother. | pmid:28096154 |
| Wind CM et al. | Trends in antimicrobial susceptibility for azithromycin and ceftriaxone in Neisseria gonorrhoeae isolates in Amsterdam, the Netherlands, between 2012 and 2015. | 2017 | Euro Surveill. | pmid:28079519 |
| Tita ATN et al. | Adjunctive Azithromycin Prophylaxis for Cesarean Delivery. | 2017 | N. Engl. J. Med. | pmid:28076707 |
| Giguère S | Treatment of Infections Caused by Rhodococcus equi. | 2017 | Vet. Clin. North Am. Equine Pract. | pmid:28161038 |
| Björnelius E et al. | macrolide resistance in Stockholm, Sweden. | 2017 | Sex Transm Infect | pmid:27502694 |
| O'Rourke VJ | Azithromycin as an adjunct to non-surgical periodontal therapy: a systematic review. | 2017 | Aust Dent J | pmid:27492140 |
| Illia R et al. | Role of cervical cerclage and prolonged antibiotic therapy with azithromycin in patients with previous perinatal loss amnionitis. | 2017 | J. Matern. Fetal. Neonatal. Med. | pmid:27094535 |
| Massip C et al. | Macrolide resistance in Legionella pneumophila: the role of LpeAB efflux pump. | 2017 | J. Antimicrob. Chemother. | pmid:28137939 |
| Srivastava S et al. | Failure of the azithromycin and ethambutol combination regimen in the hollow-fibre system model of pulmonary Mycobacterium avium infection is due to acquired resistance. | 2017 | J. Antimicrob. Chemother. | pmid:28922805 |
| Cole MJ et al. | Overall Low Extended-Spectrum Cephalosporin Resistance but high Azithromycin Resistance in Neisseria gonorrhoeae in 24 European Countries, 2015. | 2017 | BMC Infect. Dis. | pmid:28893203 |
| Xue Y et al. | An in vitro model of azithromycin-induced persistent Chlamydia trachomatis infection. | 2017 | FEMS Microbiol. Lett. | pmid:28854672 |
| Barberá MJ et al. | Mycoplasma genitalium Macrolide and Fluoroquinolone Resistance: Prevalence and Risk Factors Among a 2013-2014 Cohort of Patients in Barcelona, Spain. | 2017 | Sex Transm Dis | pmid:28703723 |
| Brusselle G and Pavord I | Azithromycin in uncontrolled asthma. | 2017 | Lancet | pmid:28687412 |
| Fohner AE et al. | PharmGKB summary: Macrolide antibiotic pathway, pharmacokinetics/pharmacodynamics. | 2017 | Pharmacogenet. Genomics | pmid:28146011 |
| Teng F et al. | In vitro characterization of pH-sensitive azithromycin-loaded methoxy poly (ethylene glycol)-block-poly (aspartic acid-graft-imidazole) micelles. | 2017 | J Colloid Interface Sci | pmid:28209540 |
| Koop AH et al. | 56-Year-Old Woman With Cough and Fatigue for 1 Week. | 2017 | Mayo Clin. Proc. | pmid:28110893 |
| Murray K et al. | Increasing Antibiotic Resistance in Shigella spp. from Infected New York City Residents, New York, USA. | 2017 | Emerging Infect. Dis. | pmid:28098543 |
| Nichols DP et al. | Impact of azithromycin on the clinical and antimicrobial effectiveness of tobramycin in the treatment of cystic fibrosis. | 2017 | J. Cyst. Fibros. | pmid:28025037 |
| Marks M et al. | Mathematical Modeling of Programmatic Requirements for Yaws Eradication. | 2017 | Emerging Infect. Dis. | pmid:27983500 |