Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Abnormalities, Drug-Induced D000014 10 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Abscess D000038 13 associated lipids
Achondroplasia D000130 1 associated lipids
Acinetobacter Infections D000151 4 associated lipids
Acne Vulgaris D000152 35 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Actinomycetales Infections D000193 4 associated lipids
Agammaglobulinemia D000361 4 associated lipids
Airway Obstruction D000402 13 associated lipids
Amebiasis D000562 2 associated lipids
Anaphylaxis D000707 35 associated lipids
Anaplasmataceae Infections D000711 3 associated lipids
Angina, Unstable D000789 14 associated lipids
Aphasia, Broca D001039 1 associated lipids
Arteriosclerosis D001161 86 associated lipids
Arthritis D001168 41 associated lipids
Arthritis, Infectious D001170 8 associated lipids
Bacterial Infections D001424 21 associated lipids
Bartonella Infections D001474 3 associated lipids
Birth Weight D001724 23 associated lipids
Bites, Human D001734 2 associated lipids
Blister D001768 16 associated lipids
Body Weight D001835 333 associated lipids
Boutonneuse Fever D001907 5 associated lipids
Bronchiolitis D001988 6 associated lipids
Bronchiolitis Obliterans D001989 8 associated lipids
Burns D002056 34 associated lipids
Carcinoma, Basal Cell D002280 6 associated lipids
Carcinoma, Squamous Cell D002294 14 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Cat Diseases D002371 12 associated lipids
Cat-Scratch Disease D002372 4 associated lipids
Uterine Cervicitis D002575 3 associated lipids
Chancroid D002602 4 associated lipids
Chlamydia Infections D002690 7 associated lipids
Chlamydiaceae Infections D002694 2 associated lipids
Chronic Disease D002908 7 associated lipids
Ciliary Motility Disorders D002925 2 associated lipids
Colitis D003092 69 associated lipids
Conjunctivitis, Bacterial D003234 3 associated lipids
Conjunctivitis, Inclusion D003235 4 associated lipids
Corneal Opacity D003318 3 associated lipids
Coronary Disease D003327 70 associated lipids
Corynebacterium Infections D003354 7 associated lipids
Crohn Disease D003424 12 associated lipids
Cross Infection D003428 9 associated lipids
Cryptosporidiosis D003457 3 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Cytomegalovirus Infections D003586 7 associated lipids
Drug Eruptions D003875 30 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diarrhea D003967 32 associated lipids
Digestive System Diseases D004066 3 associated lipids
Dog Diseases D004283 5 associated lipids
Drug Hypersensitivity D004342 20 associated lipids
Dry Socket D004368 3 associated lipids
Dysentery, Bacillary D004405 6 associated lipids
Dyspnea D004417 10 associated lipids
Ectodermal Dysplasia D004476 1 associated lipids
Edema D004487 152 associated lipids
Eisenmenger Complex D004541 1 associated lipids
Elephantiasis D004604 2 associated lipids
Elephantiasis, Filarial D004605 4 associated lipids
Encephalomyelitis, Autoimmune, Experimental D004681 26 associated lipids
Enteritis D004751 8 associated lipids
Epiglottitis D004826 1 associated lipids
Erythema Nodosum D004893 5 associated lipids
Escherichia coli Infections D004927 17 associated lipids
Exanthema D005076 11 associated lipids
Eye Diseases D005128 12 associated lipids
Eyelid Diseases D005141 4 associated lipids
Fatty Liver D005234 48 associated lipids
Fetal Membranes, Premature Rupture D005322 4 associated lipids
Fever D005334 35 associated lipids
Fever of Unknown Origin D005335 3 associated lipids
Food Hypersensitivity D005512 7 associated lipids
Furunculosis D005667 2 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Genital Diseases, Female D005831 7 associated lipids
Genital Diseases, Male D005832 3 associated lipids
Giardiasis D005873 3 associated lipids
Gingival Hyperplasia D005885 3 associated lipids
Gonorrhea D006069 7 associated lipids
Granuloma Inguinale D006100 2 associated lipids
Haemophilus Infections D006192 3 associated lipids
Hearing Disorders D006311 10 associated lipids
Hearing Loss, Conductive D006314 2 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Heart Defects, Congenital D006330 20 associated lipids
Heartburn D006356 2 associated lipids
Hemolysis D006461 131 associated lipids
Hernia, Hiatal D006551 3 associated lipids
Herpes Genitalis D006558 2 associated lipids
HIV Seropositivity D006679 15 associated lipids
Hoarseness D006685 2 associated lipids
Hyperbilirubinemia D006932 11 associated lipids
Hyperglycemia D006943 21 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

Download all related citations
Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Sidhu H et al. Risk assessment of biosolids-borne ciprofloxacin and azithromycin. 2019 Sci. Total Environ. pmid:30463165
Sidhu H et al. Plant toxicity and accumulation of biosolids-borne ciprofloxacin and azithromycin. 2019 Sci. Total Environ. pmid:30340267
Sidhu H et al. Retention-release of ciprofloxacin and azithromycin in biosolids and biosolids-amended soils. 2019 Sci. Total Environ. pmid:30196217
Sidhu H et al. Bioavailability of biosolids-borne ciprofloxacin and azithromycin to terrestrial organisms: Microbial toxicity and earthworm responses. 2019 Sci. Total Environ. pmid:30195128
Horner P et al. Which azithromycin regimen should be used for treating ? A meta-analysis. 2018 Sex Transm Infect pmid:28717050
Latif AS et al. Antimicrobial susceptibility in isolates from five sentinel surveillance sites in Zimbabwe, 2015-2016. 2018 Sex Transm Infect pmid:28476914
de Oliveira Alves A et al. Young Boy With Roughening in the Inner Eyelids. 2018 Ann Emerg Med pmid:29458812
Astale T et al. Population-based coverage survey results following the mass drug administration of azithromycin for the treatment of trachoma in Amhara, Ethiopia. 2018 PLoS Negl Trop Dis pmid:29451881
Šmajs D and Pospíšilová P Macrolide resistance in yaws. 2018 Lancet pmid:29428184
Mitjà O et al. Re-emergence of yaws after single mass azithromycin treatment followed by targeted treatment: a longitudinal study. 2018 Lancet pmid:29428183
Brereton CJ et al. Is gentamicin safe and effective for severe community-acquired pneumonia? An 8-year retrospective cohort study. 2018 Int. J. Antimicrob. Agents pmid:29410326
Ting CY and Shahdadpuri R Fuchs syndrome: a case of fever, mucositis and conjunctivitis. 2018 BMJ Case Rep pmid:29378740
Huang S et al. Human babesiosis in Southeast China: A case report. 2018 Int. J. Infect. Dis. pmid:29355731
Jenson A et al. Patient-centered communication of community treatment assistants in Tanzania predicts coverage of future mass drug administration for trachoma. 2018 Patient Educ Couns pmid:29329726
Sarathchandran P et al. infection presenting as stroke and meningoencephalitis with aortic and subclavian aneurysms without pulmonary involvement. 2018 BMJ Case Rep pmid:29326371
Mascarenhas TR et al. Tick-borne illness after transplantation: Case and review. 2018 Transpl Infect Dis pmid:29277955
Casas-Maldonado F Bronchiectasis and Azithromycin. 2018 Arch. Bronconeumol. pmid:28757281
Zhao L et al. Trends in antimicrobial resistance in Neisseria gonorrhoeae and molecular characteristics of N. gonorrhoeae with decreased susceptibility to ceftriaxone in Shandong, China, 2007 to 2014. 2018 Int. J. Antimicrob. Agents pmid:28729124
Bakshi SS In reference to 'Therapeutic efficacy of azithromycin and acetylcysteine in chronic otitis media with effusion'. 2018 Eur Arch Otorhinolaryngol pmid:28612316
Revello R et al. Prediction of chorioamnionitis in cases of intraamniotic infection by ureaplasma urealyticum in women with very preterm premature rupture of membranes or preterm labour. 2018 J. Matern. Fetal. Neonatal. Med. pmid:28502201
Ersoy B et al. The anti-inflammatory effects of erythromycin, clarithromycin, azithromycin and roxithromycin on histamine-induced otitis media with effusion in guinea pigs. 2018 J Laryngol Otol pmid:29888693
Lietman TM et al. Identifying a sufficient core group for trachoma transmission. 2018 PLoS Negl Trop Dis pmid:30296259
Hassan KS and Al-Khadouri G Pneumonia with Worsening Pleural Effusion Despite Treatment with Appropriate Antimicrobials: Case report. 2018 Sultan Qaboos Univ Med J pmid:30210860
Williams PCM and Berkley JA Guidelines for the management of paediatric cholera infection: a systematic review of the evidence. 2018 Paediatr Int Child Health pmid:29790841
Al-Darraji A et al. Azithromycin therapy reduces cardiac inflammation and mitigates adverse cardiac remodeling after myocardial infarction: Potential therapeutic targets in ischemic heart disease. 2018 PLoS ONE pmid:30001416
Glanternik JR et al. A Cluster of Cases of Babesia microti Among Neonates Traced to a Single Unit of Donor Blood. 2018 Pediatr. Infect. Dis. J. pmid:28945680
Li JG et al. [Eperythrozoonosis complicated with hemophagocytic syndrome: report of four cases and review of literature]. 2018 Zhonghua Er Ke Za Zhi pmid:29614573
Xu L et al. Nursing care of a boy seriously infected with Steven-Johnson syndrome after treatment with azithromycin: A case report and literature review. 2018 Medicine (Baltimore) pmid:29505509
Mikalová L and Šmajs D Low-dose versus standard-dose azithromycin for treatment of yaws. 2018 Lancet Glob Health pmid:29456192
Cai X et al. Anti-N-methyl-D-aspartate receptor encephalitis associated with acute Toxoplasma gondii infection: A case report. 2018 Medicine (Baltimore) pmid:29443773
Yang D et al. The timing of azithromycin treatment is not associated with the clinical prognosis of childhood Mycoplasma pneumoniae pneumonia in high macrolide-resistant prevalence settings. 2018 PLoS ONE pmid:29377957
Morales A et al. Microbiological and clinical effects of probiotics and antibiotics on nonsurgical treatment of chronic periodontitis: a randomized placebo- controlled trial with 9-month follow-up. 2018 J Appl Oral Sci pmid:29364340
Buder S et al. Antimicrobial resistance of Neisseria gonorrhoeae in Germany: low levels of cephalosporin resistance, but high azithromycin resistance. 2018 BMC Infect. Dis. pmid:29343220
Crooks MG et al. How does azithromycin improve asthma exacerbations? 2018 Lancet pmid:29323653
Gibson PG How does azithromycin improve asthma exacerbations? - Author's reply. 2018 Lancet pmid:29323652
Sanchez Garcia D et al. Cellular accumulation and lipid binding of perfluorinated alkylated substances (PFASs) - A comparison with lysosomotropic drugs. 2018 Chem. Biol. Interact. pmid:29248446
Obaro S Azithromycin and Childhood Mortality in Africa. 2018 N. Engl. J. Med. pmid:30284804
Michelow IC and Sánchez PJ Azithromycin and Childhood Mortality in Africa. 2018 N. Engl. J. Med. pmid:30284803
Kalua K et al. One round of azithromycin MDA adequate to interrupt transmission in districts with prevalence of trachomatous inflammation-follicular of 5.0-9.9%: Evidence from Malawi. 2018 PLoS Negl Trop Dis pmid:29897902
Smotrys M et al. Babesiosis as a cause of false-positive HIV serology. 2018 BMJ Case Rep pmid:29884713
Nüesch-Inderbinen M et al. Genetic characterization of Shiga toxin producing Escherichia coli belonging to the emerging hybrid pathotype O80:H2 isolated from humans 2010-2017 in Switzerland. 2018 Int. J. Med. Microbiol. pmid:29884331
Iguidbashian JP et al. and coinfection in the setting of ulcerative colitis. 2018 BMJ Case Rep pmid:29880626
Lendermon EA et al. Azithromycin Fails to Prevent Accelerated Airway Obliteration in T-bet Mouse Lung Allograft Recipients. 2018 Transplant. Proc. pmid:29880387
Lam-Franco L et al. IL-1α and MMP-9 Tear Levels of Patients with Active Ocular Rosacea before and after Treatment with Systemic Azithromycin or Doxycycline. 2018 Ophthalmic Res. pmid:29874670
Saita MG et al. pH-Dependent stability of azithromycin in aqueous solution and structure identification of two new degradation products. 2018 J Pharm Biomed Anal pmid:29860178
Naderi N et al. Long-term azithromycin therapy to reduce acute exacerbations in patients with severe chronic obstructive pulmonary disease. 2018 Respir Med pmid:29724384
Zmora N et al. Open label comparative trial of mono versus dual antibiotic therapy for Typhoid Fever in adults. 2018 PLoS Negl Trop Dis pmid:29684022
Wei W et al. MPEG-PCL Copolymeric Micelles for Encapsulation of Azithromycin. 2018 AAPS PharmSciTech pmid:29675667
Barge L et al. Transient immune-mediated agranulocytosis following infection. 2018 BMJ Case Rep pmid:29669774
Papp JR et al. Accuracy and reproducibility of the Etest to detect drug-resistant Neisseria gonorrhoeae to contemporary treatment. 2018 J. Med. Microbiol. pmid:29219803