Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Azithramycine
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Schouten JT and Whittemore S | Recent development in the treatment and prevention of disseminated Mycobacterium avium complex (MAC). | 1996 | STEP Perspect | pmid:11364267 |
Foulds G et al. | The absence of an effect of food on the bioavailability of azithromycin administered as tablets, sachet or suspension. | 1996 | J. Antimicrob. Chemother. | pmid:8818844 |
Vaudaux BP et al. | Concentrations of azithromycin in tonsilar and/or adenoid tissue from paediatric patients. | 1996 | J. Antimicrob. Chemother. | pmid:8818845 |
Pukander J and Rautianen M | Penetration of azithromycin into middle ear effusions in acute and secretory otitis media in children. | 1996 | J. Antimicrob. Chemother. | pmid:8818846 |
Rodriguez AF | An open study to compare azithromycin with cefaclor in the treatment of children with acute otitis media. | 1996 | J. Antimicrob. Chemother. | pmid:8818847 |
Hultén K et al. | New pharmacokinetic in vitro model for studies of antibiotic activity against intracellular microorganisms. | 1996 | Antimicrob. Agents Chemother. | pmid:9124830 |
Marchisio P et al. | Comparative study of once-weekly azithromycin and once-daily amoxicillin treatments in prevention of recurrent acute otitis media in children. | 1996 | Antimicrob. Agents Chemother. | pmid:9124831 |
McCutchan JA | Azithromycin in the prophylaxis of opportunistic infections in AIDS. | 1996 | Int J STD AIDS | pmid:8652726 |
Ridgway GL | Azithromycin in the management of Chlamydia trachomatis infections. | 1996 | Int J STD AIDS | pmid:8652727 |
Ballard RC et al. | Treatment of chancroid with azithromycin. | 1996 | Int J STD AIDS | pmid:8652728 |
Bowden FJ et al. | Pilot study of azithromycin in the treatment of genital donovanosis. | 1996 | Genitourin Med | pmid:8655160 |
Luke DR et al. | Safety, toleration, and pharmacokinetics of intravenous azithromycin. | 1996 | Antimicrob. Agents Chemother. | pmid:8913468 |
Olsen KM et al. | Intrapulmonary pharmacokinetics of azithromycin in healthy volunteers given five oral doses. | 1996 | Antimicrob. Agents Chemother. | pmid:8913469 |
Kuo CC et al. | In vitro activities of azithromycin, clarithromycin, and other antibiotics against Chlamydia pneumoniae. | 1996 | Antimicrob. Agents Chemother. | pmid:8913488 |
Magid D et al. | Doxycycline compared with azithromycin for treating women with genital Chlamydia trachomatis infections: an incremental cost-effectiveness analysis. | 1996 | Ann. Intern. Med. | pmid:8554247 |
Roord JJ et al. | Prospective open randomized study comparing efficacies and safeties of a 3-day course of azithromycin and a 10-day course of erythromycin in children with community-acquired acute lower respiratory tract infections. | 1996 | Antimicrob. Agents Chemother. | pmid:9124837 |
McLinn S | A multicenter, double blind comparison of azithromycin and amoxicillin/ clavulanate for the treatment of acute otitis media in children. | 1996 | Pediatr. Infect. Dis. J. | pmid:8878242 |
Khurana CM | A multicenter, randomized, open label comparison of azithromycin and amoxicillin/clavulanate in acute otitis media among children attending day care or school. | 1996 | Pediatr. Infect. Dis. J. | pmid:8878243 |
Powers JL | Properties of azithromycin that enhance the potential for compliance in children with upper respiratory tract infections. | 1996 | Pediatr. Infect. Dis. J. | pmid:8878244 |
Wenisch C et al. | Effect of single oral dose of azithromycin, clarithromycin, and roxithromycin on polymorphonuclear leukocyte function assessed ex vivo by flow cytometry. | 1996 | Antimicrob. Agents Chemother. | pmid:8878577 |