Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Azithramycine
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Skerk V et al. | Comparative analysis of azithromycin and doxycycline efficacy in the treatment of female patients with acute urethral syndrome caused by Ureaplasma urealyticum. | 2000 | J Chemother | pmid:10789560 |
Kozyrskyj AL et al. | Short course antibiotics for acute otitis media. | 2000 | Cochrane Database Syst Rev | pmid:10796591 |
Sasaki TY and Sumida KN | Angioimmunoblastic T-cell lymphoma (AIL-TCL) following macrolide administration. | 2000 | Hawaii Med J | pmid:10800250 |
Vergis EN et al. | Azithromycin vs cefuroxime plus erythromycin for empirical treatment of community-acquired pneumonia in hospitalized patients: a prospective, randomized, multicenter trial. | 2000 | Arch. Intern. Med. | pmid:10809032 |
Turcinov D et al. | Failure of azithromycin in treatment of Brill-Zinsser disease. | 2000 | Antimicrob. Agents Chemother. | pmid:10817744 |
Tsitsika A et al. | Single-oral-dose azithromycin prophylaxis against experimental streptococcal or staphylococcal aortic valve endocarditis. | 2000 | Antimicrob. Agents Chemother. | pmid:10817749 |
Bin XX et al. | Effect of azithromycin plus rifampin versus amoxicillin alone on eradication and inflammation in the chronic course of Chlamydia pneumoniae pneumonitis in mice. | 2000 | Antimicrob. Agents Chemother. | pmid:10817751 |
Zuckerman JM | The newer macrolides: azithromycin and clarithromycin. | 2000 | Infect. Dis. Clin. North Am. | pmid:10829265 |
Mirmiran R et al. | Disseminated gonococcal infection: a case of beta-lactamase-producing Neisseria gonorrhoeae. | 2000 | J Am Podiatr Med Assoc | pmid:10833879 |
Straubinger RK | PCR-Based quantification of Borrelia burgdorferi organisms in canine tissues over a 500-Day postinfection period. | 2000 | J. Clin. Microbiol. | pmid:10834975 |
Moshkani SK and Dalimi A | Evaluation of the efficacy of atovaquone alone or in combination with azithromycin against acute murine toxoplasmosis. | 2000 | Vet. Res. Commun. | pmid:10836275 |
Matute AJ et al. | Is a 5 day course of azithromycin enough for infections caused by Legionella pneumophila? | 2000 | J. Antimicrob. Chemother. | pmid:10837459 |
Anderson JL and Muhlestein JB | The ACADEMIC study in perspective (Azithromycin in coronary artery disease: elimination of myocardial infection with Chlamydia). | 2000 | J. Infect. Dis. | pmid:10839761 |
Dunne MW | Rationale and design of a secondary prevention trial of antibiotic use in patients after myocardial infarction: the WIZARD (weekly intervention with zithromax [azithromycin] for atherosclerosis and its related disorders) trial. | 2000 | J. Infect. Dis. | pmid:10839762 |
Jackson LA | Description and status of the azithromycin and coronary events study (ACES). | 2000 | J. Infect. Dis. | pmid:10839763 |
Heikkinen T et al. | The transplacental transfer of the macrolide antibiotics erythromycin, roxithromycin and azithromycin. | 2000 | BJOG | pmid:10847234 |
Raja Babu KK et al. | Confluent and reticulate papillomatosis: successful treatment with azithromycin. | 2000 | Br. J. Dermatol. | pmid:10848767 |
Ernst EJ et al. | Comparison of the serum and intracellular pharmacokinetics of azithromycin in healthy and diabetic volunteers. | 2000 | Pharmacotherapy | pmid:10853621 |
Criqui GI et al. | Effects of azithromycin on ozone-induced airway neutrophilia and cytokine release. | 2000 | Eur. Respir. J. | pmid:10853849 |
Plouffe J et al. | Clinical efficacy of intravenous followed by oral azithromycin monotherapy in hospitalized patients with community-acquired pneumonia. The Azithromycin Intravenous Clinical Trials Group. | 2000 | Antimicrob. Agents Chemother. | pmid:10858333 |