Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Roblin PM and Hammerschlag MR | Microbiologic efficacy of azithromycin and susceptibilities to azithromycin of isolates of Chlamydia pneumoniae from adults and children with community-acquired pneumonia. | 1998 | Antimicrob. Agents Chemother. | pmid:9449287 |
| Bermudez LE et al. | Emergence of Mycobacterium avium populations resistant to macrolides during experimental chemotherapy. | 1998 | Antimicrob. Agents Chemother. | pmid:9449283 |
| Nguyen MH et al. | Potentiation of antifungal activity of amphotericin B by azithromycin against Aspergillus species. | 1997 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:9447909 |
| Malizia T et al. | Periodontal tissue disposition of azithromycin. | 1997 | J. Periodontol. | pmid:9444596 |
| Kalenić S et al. | Helicobacter pylori: in vitro induction of resistance to azithromycin. | 1998 Jan-Feb | Chemotherapy | pmid:9444404 |
| Edelstein PH | Legionnaires' disease. | 1998 | N. Engl. J. Med. | pmid:9441231 |
| Hillis SD et al. | Doxycycline and azithromycin for prevention of chlamydial persistence or recurrence one month after treatment in women. A use-effectiveness study in public health settings. | 1998 | Sex Transm Dis | pmid:9437777 |
| Nyström-Rosander C et al. | Susceptibility of Chlamydia pneumoniae to azithromycin and doxycycline: methodological aspects on the determination of minimal inhibitory and minimal bactericidal concentrations. | 1997 | Scand. J. Infect. Dis. | pmid:9435043 |
| [New ways of antibiotic therapy]. | 1995 | Internist (Berl) | pmid:9431354 | |
| Gómez E et al. | Treatment of cyclosporin-induced gingival hyperplasia with azithromycin. | 1997 | Nephrol. Dial. Transplant. | pmid:9430874 |
| Feldman C et al. | Roxithromycin, clarithromycin, and azithromycin attenuate the injurious effects of bioactive phospholipids on human respiratory epithelium in vitro. | 1997 | Inflammation | pmid:9429912 |
| Champney WS and Burdine R | Azithromycin and clarithromycin inhibition of 50S ribosomal subunit formation in Staphylococcus aureus cells. | 1998 | Curr. Microbiol. | pmid:9425251 |
| Kobayashi I et al. | A new semi-solid agar dilution method for determining amoxycillin, clarithromycin and azithromycin MICs for Helicobacter pylori isolates. | 1997 | J. Antimicrob. Chemother. | pmid:9421321 |
| Lo Bue AM et al. | Antimicrobial interference of a subinhibitory concentration of azithromycin on fimbrial production of Porphyromonas gingivalis. | 1997 | J. Antimicrob. Chemother. | pmid:9421312 |
| Klausner JD et al. | Enhanced control of an outbreak of Mycoplasma pneumoniae pneumonia with azithromycin prophylaxis. | 1998 | J. Infect. Dis. | pmid:9419183 |
| Cohen DA et al. | A school-based Chlamydia control program using DNA amplification technology. | 1998 | Pediatrics | pmid:9417165 |
| Barry AL et al. | In vitro activity of the new ketolide HMR 3004 compared to an azalide and macrolides against Streptococcus pneumoniae and Haemophilus influenzae. | 1997 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:9405952 |
| Cadle RM et al. | Symptomatic syndrome of inappropriate antidiuretic hormone secretion associated with azithromycin. | 1997 | Ann Pharmacother | pmid:9391684 |
| Fichera ME and Roos DS | A plastid organelle as a drug target in apicomplexan parasites. | 1997 | Nature | pmid:9389481 |
| Kränke B and Aberer W | Macrolide-induced Churg-Strauss syndrome in patient with atopy. | 1997 | Lancet | pmid:9388427 |