Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Azithramycine
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Mitrokhin SD et al. | [Susceptibility of community-acquired pneumonia pathogens to azithromycin]. | 1998 | Antibiot. Khimioter. | pmid:9606504 |
Andreeva IV et al. | [Diagnostic and treatment patterns in management of male patients with nongonococcal urethritis: results of Russian multicentral cross-sectional study]. | 2012 | Antibiot. Khimioter. | pmid:23156042 |
Sher AA et al. | [Interactions in the system of copper ion-azalide (azithromycin)]. | 1994 Sep-Oct | Antibiot. Khimioter. | pmid:7695446 |
Khrianin AA et al. | [Efficacy of azithromycin and its impact on cytokine system in urogenital infections]. | 2012 | Antibiot. Khimioter. | pmid:22993937 |
Suskova VS et al. | [Immuno-modulating properties of a macrolide antibiotic "Z-factor"]. | 2003 | Antibiot. Khimioter. | pmid:15002174 |
Pisarev VV et al. | [Comparative study of azithromycin pharmacokinetics in healthy volunteers in open cross randomized procedure]. | 2003 | Antibiot. Khimioter. | pmid:15004973 |
Bogomil'skiÄ MP and Komarov RM | [Azithromycin in the treatment of acute otitis media]. | 2002 | Antibiot. Khimioter. | pmid:12515096 |
Hand WI and Hand DL | [Mechanisms of azithromycin accumulation and efflux in human polymorphonuclear leukocytes]. | 2002 | Antibiot. Khimioter. | pmid:12516190 |
ZaÄtseva EA et al. | [Comparative study of the antimicrobial activity of pefloxacin, ciprofloxacin, norfloxacin and azithromycin with respect to Strains of Yersinia pseudotuberculosis]. | 1996 | Antibiot. Khimioter. | pmid:8762820 |
Karpov OI | [The clinical and economic efficacies of short courses of azithromycin in acute sinusitis]. | 1999 | Antibiot. Khimioter. | pmid:10635419 |
DvoretskiÄ LI et al. | [Levofloxacin and macrolides in chronic bronchitis exacerbation: comparative analysis of the treatment efficacy and nonrelapsing periods]. | 2007 | Antibiot. Khimioter. | pmid:18986021 |
Reshetniak VI et al. | [Eradication of Helicobacter pylori in patients with duodenal ulcer following the short course of treatment with azitromycin and amoxycillin]. | 2002 | Antibiot. Khimioter. | pmid:12087718 |
Budanov SV | [Azithromycin (sumamed)--basic properties and therapy of community-acquired pneumonia]. | 2000 | Antibiot. Khimioter. | pmid:11212397 |
Gomberg MA | [Combined treatment of persisting urogenital chlamydia infection with sumamed and interferon alfa]. | 2002 | Antibiot. Khimioter. | pmid:12365322 |
Molchanova OV et al. | [Antibiotic therapy of severe community-acquired pneumonia]. | 2009 | Antibiot. Khimioter. | pmid:19711847 |
Iur'ev SIu et al. | [Azithromycin levels in the chorion tissue within the first three months of the pregnancy term]. | 2004 | Antibiot. Khimioter. | pmid:15850052 |
Tets VV et al. | [Characteristics of azithromycin action on bacterial biofilms of pneumonia pathogens]. | 2007 | Antibiot. Khimioter. | pmid:18476468 |
Iakovlev SV and Ukhin SA | [Azithromycin: general properties and regimen optimization based on pharmacokinetic and pharmacological parameters]. | 2003 | Antibiot. Khimioter. | pmid:12803047 |
Gomberg MA and MashkilleÄson AL | [Use of azithromycin in long existing urogenital chlamydia infections and its association with primary syphilis]. | 1993 | Antibiot. Khimioter. | pmid:8060178 |
Sidorenko SV | [Azithromycin--an antibiotic of the azalide group]. | 1993 | Antibiot. Khimioter. | pmid:8060181 |
Lopatkin NA et al. | [Use of azithromycin ("Sumamded") in the treatment of infectious-inflammatory diseases of the lower urinary tract and male genitalia]. | 1993 | Antibiot. Khimioter. | pmid:8060189 |
Khrianin AA et al. | [Impact of exogenous proteolytic enzymes on immunogenesis in patients with urogenital infections]. | 2012 | Antibiot. Khimioter. | pmid:23477217 |
Khrianin AA and Reshetnikov OV | [Use of macrolides in pregnancy and lactation according to evidence-based medicine: pro et contra]. | 2010 | Antibiot. Khimioter. | pmid:21400756 |
Chulig I | [Pharmacokinetic profile of azithromycin. Role in the treatment of genital Chlamydia infections]. | 1996 | Antibiot. Khimioter. | pmid:8929112 |
Kuznetsova SM | ["Sumamed in the treatment of urogenital infections"]. | 1996 | Antibiot. Khimioter. | pmid:8929115 |
Skripkin IuK et al. | [The problem of diagnosis and treatment of urogenital chlamydiosis in Russia]. | 1996 | Antibiot. Khimioter. | pmid:8929120 |
Vasil'ev MM and Gazarian IIu | [Clinico-laboratory evaluation of the effectiveness of azithromycin in the treatment of patients with Chlamydia and mixed Chlamydia-gonorrhea infections]. | 1996 | Antibiot. Khimioter. | pmid:8929122 |
Nowicki M et al. | Partial regression of advanced cyclosporin-induced gingival hyperplasia after treatment with azithromycin. A case report. | 1998 | Ann. Transplant. | pmid:10234432 |
Callaghan R and Allen M | Mycobacterium malmoense infection of the knee. | 2003 | Ann. Rheum. Dis. | pmid:14583565 |
Kvien TK et al. | Three month treatment of reactive arthritis with azithromycin: a EULAR double blind, placebo controlled study. | 2004 | Ann. Rheum. Dis. | pmid:15308521 |
Carter JD et al. | Antimicrobial treatment for Chlamydia induced reactive arthritis. | 2005 | Ann. Rheum. Dis. | pmid:15708913 |
Ress BD and Gross EM | Irreversible sensorineural hearing loss as a result of azithromycin ototoxicity. A case report. | 2000 | Ann. Otol. Rhinol. Laryngol. | pmid:10778901 |
Mamikoglu B and Mamikoglu O | Irreversible sensorineural hearing loss as a result of azithromycin ototoxicity. A case report. | 2001 | Ann. Otol. Rhinol. Laryngol. | pmid:11201801 |
Ibarra V et al. | Effect of antibiotic treatment in patients with DEBONEL/TIBOLA. | 2005 | Ann. N. Y. Acad. Sci. | pmid:16481523 |
Patel AM et al. | Statin toxicity from macrolide antibiotic coprescription: a population-based cohort study. | 2013 | Ann. Intern. Med. | pmid:23778904 |
Khan WA et al. | Treatment of shigellosis: V. Comparison of azithromycin and ciprofloxacin. A double-blind, randomized, controlled trial. | 1997 | Ann. Intern. Med. | pmid:9139555 |
Hook EW et al. | Azithromycin compared with penicillin G benzathine for treatment of incubating syphilis. | 1999 | Ann. Intern. Med. | pmid:10498560 |
Pursnani A et al. | Hypersensitivity myocarditis associated with azithromycin exposure. | 2009 | Ann. Intern. Med. | pmid:19189924 |
Wang SA et al. | Antimicrobial resistance for Neisseria gonorrhoeae in the United States, 1988 to 2003: the spread of fluoroquinolone resistance. | 2007 | Ann. Intern. Med. | pmid:17638718 |
Luft BJ et al. | Azithromycin compared with amoxicillin in the treatment of erythema migrans. A double-blind, randomized, controlled trial. | 1996 | Ann. Intern. Med. | pmid:8610947 |
Johnson JR | Therapy for Legionnaires disease. | 1999 | Ann. Intern. Med. | pmid:10366385 |
Neu HC | New macrolide antibiotics: azithromycin and clarithromycin. | 1992 | Ann. Intern. Med. | pmid:1310839 |
Sacks HS | In older adults, macrolide antibiotics were not linked to increased risk for ventricular arrhythmia. | 2016 | Ann. Intern. Med. | pmid:27323264 |
Magid D et al. | Doxycycline compared with azithromycin for treating women with genital Chlamydia trachomatis infections: an incremental cost-effectiveness analysis. | 1996 | Ann. Intern. Med. | pmid:8554247 |
Currier JS et al. | Discontinuation of Mycobacterium avium complex prophylaxis in patients with antiretroviral therapy-induced increases in CD4+ cell count. A randomized, double-blind, placebo-controlled trial. AIDS Clinical Trials Group 362 Study Team. | 2000 | Ann. Intern. Med. | pmid:11015162 |
Anderson SL et al. | Prophylaxis of Plasmodium falciparum malaria with azithromycin administered to volunteers. | 1995 | Ann. Intern. Med. | pmid:7574195 |
Kirkcaldy RD et al. | Neisseria gonorrhoeae antimicrobial resistance among men who have sex with men and men who have sex exclusively with women: the Gonococcal Isolate Surveillance Project, 2005-2010. | 2013 | Ann. Intern. Med. | pmid:23460055 |
Genç M and Mårdh A | A cost-effectiveness analysis of screening and treatment for Chlamydia trachomatis infection in asymptomatic women. | 1996 | Ann. Intern. Med. | pmid:7503471 |
Mansoor GA et al. | Azithromycin-induced acute interstitial nephritis. | 1993 | Ann. Intern. Med. | pmid:8395778 |
Glazer JL | Customer disservice? | 2006 | Ann. Intern. Med. | pmid:16389257 |