Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Tick Bites D064927 1 associated lipids
Chlamydial Pneumonia D061387 2 associated lipids
Reproductive Tract Infections D060737 1 associated lipids
Granulomatous Mastitis D058890 1 associated lipids
Trichiasis D058457 1 associated lipids
Asymptomatic Infections D058345 1 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Neglected Diseases D058069 3 associated lipids
Corneal Endothelial Cell Loss D055954 1 associated lipids
Multiple Pulmonary Nodules D055613 2 associated lipids
Acute Lung Injury D055371 33 associated lipids
Failed Back Surgery Syndrome D055111 3 associated lipids
Tracheobronchomalacia D055089 1 associated lipids
Precursor Cell Lymphoblastic Leukemia-Lymphoma D054198 10 associated lipids
Hyper-IgM Immunodeficiency Syndrome D053306 1 associated lipids
Pyomyositis D052880 2 associated lipids
Male Urogenital Diseases D052801 1 associated lipids
Tendinopathy D052256 3 associated lipids
Mucositis D052016 7 associated lipids
Pyloric Stenosis, Hypertrophic D046248 2 associated lipids
Moraxellaceae Infections D045828 3 associated lipids
Desulfovibrionaceae Infections D045824 5 associated lipids
Pulmonary Disease, Chronic Obstructive D029424 16 associated lipids
Chlamydophila Infections D023521 4 associated lipids
Communicable Diseases, Emerging D021821 3 associated lipids
Central Nervous System Protozoal Infections D020808 3 associated lipids
Multiple Sclerosis, Relapsing-Remitting D020529 7 associated lipids
Focal Nodular Hyperplasia D020518 1 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Acquired Hyperostosis Syndrome D020083 1 associated lipids
Syncope, Vasovagal D019462 1 associated lipids
Pouchitis D019449 3 associated lipids
Pseudolymphoma D019310 1 associated lipids
Gingival Overgrowth D019214 7 associated lipids
Abdominal Abscess D018784 2 associated lipids
Parasitemia D018512 5 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
T-Lymphocytopenia, Idiopathic CD4-Positive D018344 1 associated lipids
Furcation Defects D017823 1 associated lipids
Granuloma, Pyogenic D017789 2 associated lipids
Community-Acquired Infections D017714 8 associated lipids
Pelvic Pain D017699 7 associated lipids
Aortic Aneurysm, Abdominal D017544 5 associated lipids
Pityriasis Rosea D017515 3 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
AIDS-Related Opportunistic Infections D017088 9 associated lipids
Common Variable Immunodeficiency D017074 4 associated lipids
Gram-Negative Bacterial Infections D016905 16 associated lipids
Neisseriaceae Infections D016870 3 associated lipids
Ureaplasma Infections D016869 5 associated lipids
Malaria, Falciparum D016778 22 associated lipids
Leishmaniasis, Cutaneous D016773 6 associated lipids
Pneumocystis Infections D016720 1 associated lipids
Vaginosis, Bacterial D016585 10 associated lipids
Purpura, Thrombocytopenic, Idiopathic D016553 4 associated lipids
Bronchial Hyperreactivity D016535 15 associated lipids
Helicobacter Infections D016481 21 associated lipids
Lymphoma, B-Cell D016393 24 associated lipids
Uveitis, Intermediate D015867 3 associated lipids
Erythema Chronicum Migrans D015787 3 associated lipids
Corneal Edema D015715 3 associated lipids
Frontal Sinusitis D015522 1 associated lipids
Ethmoid Sinusitis D015521 2 associated lipids
Weight Loss D015431 56 associated lipids
Weight Gain D015430 101 associated lipids
Dry Eye Syndromes D015352 10 associated lipids
Mycobacterium avium-intracellulare Infection D015270 4 associated lipids
Sexually Transmitted Diseases, Bacterial D015231 5 associated lipids
Superinfection D015163 3 associated lipids
Yaws D015001 4 associated lipids
Wound Infection D014946 12 associated lipids
Whooping Cough D014917 6 associated lipids
Vomiting D014839 21 associated lipids
Vertigo D014717 4 associated lipids
Urticaria D014581 13 associated lipids
Urinary Tract Infections D014552 11 associated lipids
Urethritis D014526 9 associated lipids
Urethral Diseases D014522 4 associated lipids
Typhus, Endemic Flea-Borne D014437 3 associated lipids
Typhoid Fever D014435 2 associated lipids
Tuberculosis, Urogenital D014401 2 associated lipids
Tuberculosis, Pulmonary D014397 18 associated lipids
Tuberculosis, Avian D014379 2 associated lipids
Trismus D014313 1 associated lipids
Trichomonas Infections D014245 3 associated lipids
Toxoplasmosis, Ocular D014126 2 associated lipids
Toxoplasmosis, Congenital D014125 2 associated lipids
Toxoplasmosis D014123 9 associated lipids
Tooth, Impacted D014095 9 associated lipids
Tooth Mobility D014086 2 associated lipids
Tooth Erosion D014077 2 associated lipids
Tick Infestations D013984 4 associated lipids
Tenosynovitis D013717 3 associated lipids
Syphilis, Latent D013592 4 associated lipids
Syphilis D013587 6 associated lipids
Stomatitis D013280 14 associated lipids
Stomach Ulcer D013276 75 associated lipids
Stomach Diseases D013272 7 associated lipids
Stevens-Johnson Syndrome D013262 3 associated lipids
Staphylococcal Infections D013203 15 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

Download all related citations
Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Wareham DW and Bean DC In-vitro activity of polymyxin B in combination with imipenem, rifampicin and azithromycin versus multidrug resistant strains of Acinetobacter baumannii producing OXA-23 carbapenemases. 2006 Ann. Clin. Microbiol. Antimicrob. pmid:16630352
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Luft BJ et al. Azithromycin compared with amoxicillin in the treatment of erythema migrans. A double-blind, randomized, controlled trial. 1996 Ann. Intern. Med. pmid:8610947
Johnson JR Therapy for Legionnaires disease. 1999 Ann. Intern. Med. pmid:10366385
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Magid D et al. Doxycycline compared with azithromycin for treating women with genital Chlamydia trachomatis infections: an incremental cost-effectiveness analysis. 1996 Ann. Intern. Med. pmid:8554247
Currier JS et al. Discontinuation of Mycobacterium avium complex prophylaxis in patients with antiretroviral therapy-induced increases in CD4+ cell count. A randomized, double-blind, placebo-controlled trial. AIDS Clinical Trials Group 362 Study Team. 2000 Ann. Intern. Med. pmid:11015162
Anderson SL et al. Prophylaxis of Plasmodium falciparum malaria with azithromycin administered to volunteers. 1995 Ann. Intern. Med. pmid:7574195
Kirkcaldy RD et al. Neisseria gonorrhoeae antimicrobial resistance among men who have sex with men and men who have sex exclusively with women: the Gonococcal Isolate Surveillance Project, 2005-2010. 2013 Ann. Intern. Med. pmid:23460055
Genç M and Mårdh A A cost-effectiveness analysis of screening and treatment for Chlamydia trachomatis infection in asymptomatic women. 1996 Ann. Intern. Med. pmid:7503471
Mansoor GA et al. Azithromycin-induced acute interstitial nephritis. 1993 Ann. Intern. Med. pmid:8395778
Glazer JL Customer disservice? 2006 Ann. Intern. Med. pmid:16389257
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Ibarra V et al. Effect of antibiotic treatment in patients with DEBONEL/TIBOLA. 2005 Ann. N. Y. Acad. Sci. pmid:16481523
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Carter JD et al. Antimicrobial treatment for Chlamydia induced reactive arthritis. 2005 Ann. Rheum. Dis. pmid:15708913
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