Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Azithramycine
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Stork CM et al. | Elevated International Normalized Ratio associated with long-term azithromycin therapy in a child with cerebral palsy. | 2011 | Am J Health Syst Pharm | pmid:21593229 |
Howard KB et al. | Azithromycin versus erythromycin for community-acquired pneumonia: a cost-minimization analysis. | 1999 | Am J Health Syst Pharm | pmid:10478989 |
Lockwood AM et al. | Azithromycin-induced liver injury. | 2010 | Am J Health Syst Pharm | pmid:20479103 |
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Voytilla KL et al. | Visual compatibility of azithromycin with 24 commonly used drugs during simulated Y-site delivery. | 2002 | Am J Health Syst Pharm | pmid:12004465 |
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Lo SH et al. | Azithromycin-induced hearing loss. | 1999 | Am J Health Syst Pharm | pmid:10690220 |
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Tindberg Y et al. | Helicobacter pylori eradication in children and adolescents by a once daily 6-day treatment with or without a proton pump inhibitor in a double-blind randomized trial. | 2004 | Aliment. Pharmacol. Ther. | pmid:15274666 |
Chey WD et al. | Low- versus high-dose azithromycin triple therapy for Helicobacter pylori infection. | 1998 | Aliment. Pharmacol. Ther. | pmid:9882036 |
Trevisani L et al. | Evaluation of a new ultrashort triple therapy for Helicobacter pylori disease. | 1998 | Aliment. Pharmacol. Ther. | pmid:9882037 |
Calabrese C et al. | Pantoprazole, azithromycin and tinidazole: short duration triple therapy for eradication of Helicobacter pylori infection. | 2000 | Aliment. Pharmacol. Ther. | pmid:11121909 |
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Katelaris PH et al. | Activity of metronidazole, azithromycin and three benzimidazoles on Giardia lamblia growth and attachment to a human intestinal cell line. | 1994 | Aliment. Pharmacol. Ther. | pmid:8038350 |
Cammarota G et al. | Helicobacter pylori eradication using one-week low-dose lansoprazole plus amoxycillin and either clarithromycin or azithromycin. | 1996 | Aliment. Pharmacol. Ther. | pmid:8971300 |
Pilotto A et al. | Cure of Helicobacter pylori infection in the elderly: effects of eradication on gastritis and serological markers. | 1996 | Aliment. Pharmacol. Ther. | pmid:8971305 |
Vcev A et al. | Pantoprazole, amoxycillin and either azithromycin or clarithromycin for eradication of Helicobacter pylori in duodenal ulcer. | 2000 | Aliment. Pharmacol. Ther. | pmid:10632647 |
Vcev A et al. | Omeprazole, azithromycin and either amoxycillin or metronidazole in eradication of Helicobacter pylori in duodenal ulcer patients. | 1998 | Aliment. Pharmacol. Ther. | pmid:9663725 |
Preheim LC et al. | Ethanol feeding does not affect the efficacy or pharmacokinetics of azithromycin, trovafloxacin, or ceftriaxone in a rat model of pneumococcal pneumonia. | 1999 | Alcohol. Clin. Exp. Res. | pmid:10371404 |
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Nalbanski B and Nalbanski A | [Treatment of Chlamydia trachomatis with azatril]. | 2002 | Akush Ginekol (Sofiia) | pmid:11935692 |
Krumov G et al. | [Treatment of chlamydial cervicitis with azatril]. | 2002 | Akush Ginekol (Sofiia) | pmid:11935693 |
Borisov I | [A new therapeutic approach in the treatment of genital chlamydial infections. Azithromycin (Sumamed)]. | 1998 | Akush Ginekol (Sofiia) | pmid:10204275 |
Clearance to market azithromycin as prevention for a common OI in advanced AIDS. | 1996 | AIDS Patient Care STDS | pmid:11361535 | |
Prophylactic antibiotic receives speedy FDA approval to reduce MAC disease in advanced HIV. | 1996 | AIDS Patient Care STDS | pmid:11361569 | |
Azithromycin and OIs. | 1996 | AIDS Patient Care STDS | pmid:11361699 | |
Yangco BG et al. | Is primary mycobacterium avium complex prophylaxis necessary in patients with CD4 <50 cells/μL who are virologically suppressed on cART? | 2014 | AIDS Patient Care STDS | pmid:24833016 |
Benson C | Advances in the diagnosis and treatment of Mycobacterium avium complex (MAC) disease. | 1994 | AIDS Patient Care | pmid:11362136 |
Currier J | Progress report: prophylaxis and therapy for MAC. | 1996 | AIDS Clin Care | pmid:11363599 |
Old drug approved for MAC prevention. | 1996 | AIDS Alert | pmid:11363659 |