Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Azithramycine
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Chinh NT et al. | A randomized controlled comparison of azithromycin and ofloxacin for treatment of multidrug-resistant or nalidixic acid-resistant enteric fever. | 2000 | Antimicrob. Agents Chemother. | pmid:10858343 |
Miltner EC and Bermudez LE | Mycobacterium avium grown in Acanthamoeba castellanii is protected from the effects of antimicrobials. | 2000 | Antimicrob. Agents Chemother. | pmid:10858369 |
SendaÄŸ F et al. | Single dose oral azithromycin versus seven day doxycycline in the treatment of non-gonococcal mucopurulent endocervicitis. | 2000 | Aust N Z J Obstet Gynaecol | pmid:10870778 |
Scharfstein JA et al. | The cost-effectiveness of prophylaxis for Mycobacterium avium complex in AIDS. | 1999 | Int J Technol Assess Health Care | pmid:10874380 |
Gruber F et al. | Treatment of early syphilis with azithromycin. | 2000 | J Chemother | pmid:10877520 |
Barsic B et al. | Comparison of azithromycin and doxycycline in the treatment of erythema migrans. | 2000 May-Jun | Infection | pmid:10879639 |
Koch CC et al. | Apoptosis, oxidative metabolism and interleukin-8 production in human neutrophils exposed to azithromycin: effects of Streptococcus pneumoniae. | 2000 | J. Antimicrob. Chemother. | pmid:10882684 |
Herrera D et al. | The periodontal abscess (II). Short-term clinical and microbiological efficacy of 2 systemic antibiotic regimes. | 2000 | J. Clin. Periodontol. | pmid:10883868 |
McBroom JW | Medical management of interstitial pregnancy with a retained IUD. A case report. | 2000 | J Reprod Med | pmid:10900583 |
Drugs for sexually transmitted infections. | 1999 | Med Lett Drugs Ther | pmid:10906932 | |
Gomperts BN and White LK | Gonococcal hand abscess. | 2000 | Pediatr. Infect. Dis. J. | pmid:10917235 |
Hammerschlag MR | Treatment of Chlamydia pneumoniae. | 2000 | Int. J. Antimicrob. Agents | pmid:10926449 |
Rekart M et al. | Mass treatment/prophylaxis during an outbreak of infectious syphilis in Vancouver, British Columbia. | 2000 | Can. Commun. Dis. Rep. | pmid:10932390 |
Ng DK et al. | A randomized controlled trial of azithromycin and amoxycillin/clavulanate in the management of subacute childhood rhinosinusitis. | 2000 | J Paediatr Child Health | pmid:10940175 |
Vranes J | Effect of subminimal inhibitory concentrations of azithromycin on adherence of Pseudomonas aeruginosa to polystyrene. | 2000 | J Chemother | pmid:10949976 |
Dean D et al. | Evidence for long-term cervical persistence of Chlamydia trachomatis by omp1 genotyping. | 2000 | J. Infect. Dis. | pmid:10950788 |
Mandell GL and Coleman EJ | Activities of antimicrobial agents against intracellular pneumococci. | 2000 | Antimicrob. Agents Chemother. | pmid:10952618 |
Thompson C | Azithromycin v oxytetracycline for the treatment of non-specific urethritis. | 2000 | Sex Transm Infect | pmid:10961211 |
Scaglione F et al. | In vitro comparative dynamics of modified-release clarithromycin and of azithromycin. | 2000 Sep-Oct | Chemotherapy | pmid:10965100 |
Guzey M et al. | Three-day course of oral azithromycin vs topical oxytetracycline/polymyxin in treatment of active endemic trachoma. | 2000 Jul-Aug | Jpn. J. Ophthalmol. | pmid:10974295 |