Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Azithramycine
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Nash KA and Inderlied CB | Genetic basis of macrolide resistance in Mycobacterium avium isolated from patients with disseminated disease. | 1995 | Antimicrob. Agents Chemother. | pmid:8592991 |
Bohte R et al. | Levels of azithromycin and alpha-1 acid glycoprotein in serum in patients with community-acquired pneumonia. | 1995 | Antimicrob. Agents Chemother. | pmid:8593024 |
Tribble D et al. | Efficacy of azithromycin for typhoid fever. | 1995 | Clin. Infect. Dis. | pmid:8645805 |
Strickman D et al. | In vitro effectiveness of azithromycin against doxycycline-resistant and -susceptible strains of Rickettsia tsutsugamushi, etiologic agent of scrub typhus. | 1995 | Antimicrob. Agents Chemother. | pmid:8585717 |
Kuzman I et al. | Azithromycin for treatment of community acquired pneumonia caused by Legionella pneumophila: a retrospective study. | 1995 | Scand. J. Infect. Dis. | pmid:8588143 |
Patton DL et al. | The activity of azithromycin on the infectivity of Chlamydia trachomatis in human amniotic cells. | 1995 | J. Antimicrob. Chemother. | pmid:8821594 |
Ramadan MA et al. | Post-antibiotic effect of azithromycin and erythromycin on streptococcal susceptibility to phagocytosis. | 1995 | J. Med. Microbiol. | pmid:7752216 |
Martin DH et al. | Comparison of azithromycin and ceftriaxone for the treatment of chancroid. | 1995 | Clin. Infect. Dis. | pmid:8562752 |
Kieserman SP et al. | Streptococcal pharyngitis: alternative treatments. | 1995 | Ear Nose Throat J | pmid:8536567 |
van Rijsoort-Vos JH et al. | In-vitro activity of a new quinolone (CP-99,219) compared with ciprofloxacin, pefloxacin, azithromycin and penicillin against Neisseria gonorrhoeae. | 1995 | J. Antimicrob. Chemother. | pmid:8537268 |
Tajima T et al. | [Pharmacokinetic and clinical studies with azithromycin (fine granule) in the pediatric field. Pediatric Study Group of Azithromycin]. | 1995 | Jpn J Antibiot | pmid:7474329 |
Fujii R et al. | [Pharmacokinetic and clinical studies with azithromycin (capsule) in the pediatric field. Pediatric Study Group of Azithromycin]. | 1995 | Jpn J Antibiot | pmid:7474330 |
al-Assi MT et al. | Azithromycin triple therapy for Helicobacter pylori infection: azithromycin, tetracycline, and bismuth. | 1995 | Am. J. Gastroenterol. | pmid:7872278 |
Andersen SL et al. | Activity of azithromycin as a blood schizonticide against rodent and human plasmodia in vivo. | 1995 | Am. J. Trop. Med. Hyg. | pmid:7872444 |
Stamm WE et al. | Azithromycin for empirical treatment of the nongonococcal urethritis syndrome in men. A randomized double-blind study. | 1995 | JAMA | pmid:7629982 |
Schmid GP and Fontanarosa PB | Evolving strategies for management of the nongonococcal urethritis syndrome. | 1995 | JAMA | pmid:7629989 |
Sadiq ST et al. | Effects of azithromycin on malariometric indices in The Gambia. | 1995 | Lancet | pmid:7564674 |
Wawer MJ et al. | AIDS intervention in Uganda. | 1995 | Science | pmid:7570005 |
Gastearena I et al. | Determination of the alpha1-acid glycoprotein binding of azithromycin in vitro by equilibrium dialysis. | 1995 | J Chemother | pmid:8904095 |
Van Asselt GJ et al. | Susceptibility of Streptococcus pyogenes to azithromycin, clarithromycin, erythromycin and roxithromycin in vitro. | 1995 | J. Med. Microbiol. | pmid:7563004 |