Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| [Antibiotics in routine practice. With proper selection rapid success]. | 2002 | MMW Fortschr Med | pmid:12532526 | |
| [Azithromycin for pediatric indications. Brief therapy is ideal for children]. | 2002 | MMW Fortschr Med | pmid:12532527 | |
| Dakdouki GK et al. | Azithromycin-induced rash in infectious mononucleosis. | 2002 | Scand. J. Infect. Dis. | pmid:12587634 |
| Esteban J et al. | A comparison between disk diffusion and microdilution for susceptibility testing of Mycobacterium fortuitum complex. | 2002 | J Chemother | pmid:12583544 |
| Hook EW et al. | A randomized, comparative pilot study of azithromycin versus benzathine penicillin G for treatment of early syphilis. | 2002 | Sex Transm Dis | pmid:12172535 |
| Ohrt C et al. | Assessment of azithromycin in combination with other antimalarial drugs against Plasmodium falciparum in vitro. | 2002 | Antimicrob. Agents Chemother. | pmid:12121927 |
| Gandhi R et al. | Characterization of azithromycin hydrates. | 2002 | Eur J Pharm Sci | pmid:12128172 |
| Fulcher SF et al. | Delayed-onset mycobacterial keratitis after LASIK. | 2002 | Cornea | pmid:12131028 |
| Gaynor BD et al. | Rationale for mass antibiotic distribution for trachoma elimination. | 2002 | Int Ophthalmol Clin | pmid:12189619 |
| Fry AM et al. | Adverse and beneficial secondary effects of mass treatment with azithromycin to eliminate blindness due to trachoma in Nepal. | 2002 | Clin. Infect. Dis. | pmid:12145722 |
| Shelby-James TM et al. | Impact of single dose azithromycin on group A streptococci in the upper respiratory tract and skin of Aboriginal children. | 2002 | Pediatr. Infect. Dis. J. | pmid:12150171 |
| Blondeau JM | The evolution and role of macrolides in infectious diseases. | 2002 | Expert Opin Pharmacother | pmid:12150692 |
| Khan WA et al. | Comparison of single-dose azithromycin and 12-dose, 3-day erythromycin for childhood cholera: a randomised, double-blind trial. | 2002 | Lancet | pmid:12480424 |
| Weiss LM | Babesiosis in humans: a treatment review. | 2002 | Expert Opin Pharmacother | pmid:12150690 |
| Pastor E et al. | [Macrolide consumption according to geographic areas in the province of Valladolid]. | 2002 | Enferm. Infecc. Microbiol. Clin. | pmid:12433351 |
| Matute AJ et al. | Double-blind, placebo-controlled study comparing the effect of azithromycin with clarithromycin on oropharyngeal and bowel microflora in volunteers. | 2002 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:12111597 |
| Maizumi N et al. | Quantitative comparison of the cytocidal effect of seven macrolide antibiotics on human periodontal ligament fibroblasts. | 2002 | J. Periodont. Res. | pmid:12200967 |
| Paladino JA et al. | Cost-effectiveness of IV-to-oral switch therapy: azithromycin vs cefuroxime with or without erythromycin for the treatment of community-acquired pneumonia. | 2002 | Chest | pmid:12377852 |
| Mandell GL and Coleman EJ | Effect of antipyretic agents on uptake, transport, and release of antimicrobial agents by human polymorphonuclear leukocytes. | 2002 | J. Infect. Dis. | pmid:12001049 |
| Treadway G et al. | The safety of azithromycin in the treatment of adults with community-acquired respiratory tract infections. | 2002 | Int. J. Antimicrob. Agents | pmid:11932140 |
| [Unfortunately without effectiveness: chlamydia eradication after infarct]. | 2002 | MMW Fortschr Med | pmid:12014269 | |
| Suriawinata A and Min AD | A 33-year-old woman with jaundice after azithromycin use. | 2002 | Semin. Liver Dis. | pmid:12016551 |
| Evans AT et al. | Azithromycin for acute bronchitis: a randomised, double-blind, controlled trial. | 2002 | Lancet | pmid:12020525 |
| Kutlin A et al. | Effect of gemifloxacin on viability of Chlamydia pneumoniae (Chlamydophila pneumoniae) in an in vitro continuous infection model. | 2002 | J. Antimicrob. Chemother. | pmid:12003969 |
| Rustomjee R et al. | A randomized controlled trial of azithromycin versus doxycycline/ciprofloxacin for the syndromic management of sexually transmitted infections in a resource-poor setting. | 2002 | J. Antimicrob. Chemother. | pmid:12003988 |
| Voytilla KL et al. | Visual compatibility of azithromycin with 24 commonly used drugs during simulated Y-site delivery. | 2002 | Am J Health Syst Pharm | pmid:12004465 |
| Amsden GW et al. | A study of the interaction potential of azithromycin and clarithromycin with atorvastatin in healthy volunteers. | 2002 | J Clin Pharmacol | pmid:11936570 |
| Lacroix JS et al. | Symptoms and clinical and radiological signs predicting the presence of pathogenic bacteria in acute rhinosinusitis. | 2002 | Acta Otolaryngol. | pmid:11936912 |
| Ghaffar F et al. | Effects of large dosages of amoxicillin/clavulanate or azithromycin on nasopharyngeal carriage of Streptococcus pneumoniae, Haemophilus influenzae, nonpneumococcal alpha-hemolytic streptococci, and Staphylococcus aureus in children with acute otitis media. | 2002 | Clin. Infect. Dis. | pmid:11981724 |
| Edelstein PH | Predicting the emergence of antimicrobial resistance. | 2002 | Clin. Infect. Dis. | pmid:11981741 |
| Bosch-Driessen LH et al. | A prospective, randomized trial of pyrimethamine and azithromycin vs pyrimethamine and sulfadiazine for the treatment of ocular toxoplasmosis. | 2002 | Am. J. Ophthalmol. | pmid:12095805 |
| Butler T | Reduction of MIC of azithromycin for Salmonella typhi and Staphylococcus aureus in broth exposed to previous growth of Salmonella typhi. | 2002 | J. Antimicrob. Chemother. | pmid:12096025 |
| White RL et al. | Comparative activity of gatifloxacin and other antibiotics against 4009 clinical isolates of Streptococcus pneumoniae in the United States during 1999-2000. | 2002 | Diagn. Microbiol. Infect. Dis. | pmid:12106954 |
| Cohen R et al. | Comparison of two dosages of azithromycin for three days versus penicillin V for ten days in acute group A streptococcal tonsillopharyngitis. | 2002 | Pediatr. Infect. Dis. J. | pmid:12075760 |
| Schaad UB et al. | Azithromycin versus penicillin V for treatment of acute group A streptococcal pharyngitis. | 2002 | Pediatr. Infect. Dis. J. | pmid:12075761 |
| Gomberg MA | [Combined treatment of persisting urogenital chlamydia infection with sumamed and interferon alfa]. | 2002 | Antibiot. Khimioter. | pmid:12365322 |
| Hammerschlag MR | Effect of azithromycin on endothelial function of patients with coronary artery disease and evidence of Chlamydia pneumoniae infection. | 2002 | Circulation | pmid:12370232 |
| Adimora AA | Treatment of uncomplicated genital Chlamydia trachomatis infections in adults. | 2002 | Clin. Infect. Dis. | pmid:12353204 |
| Augenbraun MH | Treatment of syphilis 2001: nonpregnant adults. | 2002 | Clin. Infect. Dis. | pmid:12353205 |
| Itoh M et al. | [A case of immotile-dyskinetic cilia syndrome responding to clenbuterol hydrochloride and azithromycin]. | 2002 | Nihon Kokyuki Gakkai Zasshi | pmid:12382429 |
| Equi A et al. | Long term azithromycin in children with cystic fibrosis: a randomised, placebo-controlled crossover trial. | 2002 | Lancet | pmid:12383667 |
| Ohara T et al. | Effects of azithromycin on shiga toxin production by Escherichia coli and subsequent host inflammatory response. | 2002 | Antimicrob. Agents Chemother. | pmid:12384353 |
| Sullivan B et al. | Comparison of azithromycin and clarithromycin in triple therapy regimens for the eradication of Helicobacter pylori. | 2002 | Am. J. Gastroenterol. | pmid:12385435 |
| Brook I | Antibacterial therapy for acute group a streptococcal pharyngotonsillitis: short-course versus traditional 10-day oral regimens. | 2002 | Paediatr Drugs | pmid:12390046 |
| Tambiah J and Powell JT | Chlamydia pneumoniae antigens facilitate experimental aortic dilatation: prevention with azithromycin. | 2002 | J. Vasc. Surg. | pmid:12422113 |
| Arnez M et al. | Solitary erythema migrans in children: comparison of treatment with azithromycin and phenoxymethylpenicillin. | 2002 | Wien. Klin. Wochenschr. | pmid:12422590 |
| Maraspin V et al. | Development of erythema migrans in spite of treatment with antibiotics after a tick bite. | 2002 | Wien. Klin. Wochenschr. | pmid:12422612 |
| Hall IH et al. | Disposition and intracellular activity of azithromycin in human THP-1 acute monocytes. | 2002 | Int. J. Antimicrob. Agents | pmid:12431870 |
| Wolter JM et al. | Macrolides in cystic fibrosis: is there a role? | 2002 | Am J Respir Med | pmid:14720043 |
| Stone AF et al. | Effect of treatment for Chlamydia pneumoniae and Helicobacter pylori on markers of inflammation and cardiac events in patients with acute coronary syndromes: South Thames Trial of Antibiotics in Myocardial Infarction and Unstable Angina (STAMINA). | 2002 | Circulation | pmid:12208796 |
| Sirois F | [Delirium associated with azithromycin administration]. | 2002 | Can J Psychiatry | pmid:12211892 |
| Ortega E et al. | In vitro and ex vivo effects of erythromycin A, azithromycin and josamycin on the splenic response to specific antigens and mitogens. | 2002 | J. Antimicrob. Chemother. | pmid:12039899 |
| Steinberg JM and Srugo I | Reoccurrence of culture-positive pertussis in an infant initially treated with azithromycin and steroids. | 2002 | Arch Pediatr Adolesc Med | pmid:12361458 |
| Hauben M and Amsden GW | The association of erythromycin and infantile hypertrophic pyloric stenosis: causal or coincidental? | 2002 | Drug Saf | pmid:12381214 |
| Salaria M and Singh M | Atypical pneumonia in children. | 2002 | Indian Pediatr | pmid:11910135 |
| Desta Z et al. | In vitro inhibition of pimozide N-dealkylation by selective serotonin reuptake inhibitors and azithromycin. | 2002 | J Clin Psychopharmacol | pmid:11910261 |
| Ito N and Kudo S | [Case of polycystic lung disease with mixed infections due to Aspergillus and Mycobacterium fortuitum successfully treated by AZM]. | 2002 | Jpn J Antibiot | pmid:12664928 |
| Smith SR et al. | A double-blind placebo-controlled trial of azithromycin as an adjunct to non-surgical treatment of periodontitis in adults: clinical results. | 2002 | J. Clin. Periodontol. | pmid:11846850 |
| Wu ML et al. | Enterocolonic Mycobacterium avium-intracellulare. | 2002 | Arch. Pathol. Lab. Med. | pmid:11860323 |
| Cascio A and Colomba C | [Macrolides in the treatment of children with Mediterranean spotted fever]. | 2002 | Infez Med | pmid:12704264 |
| Parchure N et al. | Effect of azithromycin treatment on endothelial function in patients with coronary artery disease and evidence of Chlamydia pneumoniae infection. | 2002 | Circulation | pmid:11901039 |
| SoRelle R | Treatment with azithromycin improves endothelial function. | 2002 | Circulation | pmid:11902195 |
| Firsov AA et al. | Comparative pharmacodynamics of azithromycin and roxithromycin with S. pyogenes and S. pneumoniae in a model that simulates in vitro pharmacokinetics in human tonsils. | 2002 | J. Antimicrob. Chemother. | pmid:11751774 |
| Rapp RP | Clinical and economic outcomes in respiratory tract infections: The impact of bacterial resistance. | 2002 | Postgrad Med | pmid:19667590 |
| Zubata P et al. | A new HPLC method for azithromycin quantitation. | 2002 | J Pharm Biomed Anal | pmid:11814725 |
| Lentino JR and Krasnicka B | Association between initial empirical therapy and decreased length of stay among veteran patients hospitalized with community acquired pneumonia. | 2002 | Int. J. Antimicrob. Agents | pmid:11814769 |
| Phillips P et al. | Azithromycin prophylaxis for Mycobacterium avium complex during the era of highly active antiretroviral therapy: evaluation of a provincial program. | 2002 | Clin. Infect. Dis. | pmid:11774085 |
| Lau CY and Qureshi AK | Azithromycin versus doxycycline for genital chlamydial infections: a meta-analysis of randomized clinical trials. | 2002 | Sex Transm Dis | pmid:12218839 |
| Culić O et al. | Azithromycin modulates neutrophil function and circulating inflammatory mediators in healthy human subjects. | 2002 | Eur. J. Pharmacol. | pmid:12208321 |
| Silva FM et al. | Low efficacy of an ultra-short term, once-daily dose triple therapy with omeprazole, azithromycin, and secnidazole for Helicobacter pylori eradication in peptic ulcer. | 2002 Jan-Feb | Rev Hosp Clin Fac Med Sao Paulo | pmid:12170343 |
| Kadappu KK et al. | Azithromycin as treatment for cryptosporidiosis in human immunodeficiency virus disease. | 2002 Jul-Sep | J Postgrad Med | pmid:12432190 |
| Yaqubi GH and Anani GR | Prevalence of trachoma in chronic conjunctivitis, Birjand, Islamic Republic of Iran. | 2002 Mar-May | East. Mediterr. Health J. | pmid:15339124 |
| Basilion EV et al. | Height as a proxy for weight in determining azithromycin treatment for paediatric trachoma. | 2002 Nov-Dec | Trans. R. Soc. Trop. Med. Hyg. | pmid:12625152 |
| Mileusnic D et al. | Pathological case of the month: sudden death in a child as a result of pancreatitis during valproic acid therapy. | 2002 Sep-Oct | Pediatr Pathol Mol Med | pmid:12396903 |
| Bingen E et al. | Activity of telithromycin against penicillin-resistant Streptococcus pneumoniae isolates recovered from French children with invasive and noninvasive infections. | 2003 | Antimicrob. Agents Chemother. | pmid:12821495 |
| Arreaza L et al. | Emergence of gonococcal strains with resistance to azithromycin in Spain. | 2003 | J. Antimicrob. Chemother. | pmid:12493814 |
| Schillinger JA et al. | Patient-delivered partner treatment with azithromycin to prevent repeated Chlamydia trachomatis infection among women: a randomized, controlled trial. | 2003 | Sex Transm Dis | pmid:12514443 |
| Jennings MB et al. | Comparison of azithromycin and cefadroxil for the treatment of uncomplicated skin and skin structure infections. | 2003 | Cutis | pmid:14533837 |
| Callaghan R and Allen M | Mycobacterium malmoense infection of the knee. | 2003 | Ann. Rheum. Dis. | pmid:14583565 |
| Niederman MS | [Conservative use of antibiotics is important, but: "Resistance hysteria is exaggerated"]. | 2003 | MMW Fortschr Med | pmid:14584217 |
| Cotter CJ and Bierne JC | Azithromycin for odontogenic infection. | 2003 | J. Oral Maxillofac. Surg. | pmid:14586869 |
| Lildholdt T et al. | The natural history of recurrent acute tonsillitis and a clinical trial of azithromycin for antibiotic prophylaxis. | 2003 | Clin Otolaryngol Allied Sci | pmid:12871256 |
| Gribajcević M et al. | [Clinical effectiveness of omeprazole, azithromycin and amoxicillin in ulcer healing and eradication of Helicobacter pylori infection]. | 2003 | Med Arh | pmid:15137249 |
| Saiman L et al. | Azithromycin in patients with cystic fibrosis chronically infected with Pseudomonas aeruginosa: a randomized controlled trial. | 2003 | JAMA | pmid:14519709 |
| Schlünzen F et al. | Structural basis for the antibiotic activity of ketolides and azalides. | 2003 | Structure | pmid:12623020 |
| Zhanel GG et al. | Pharmacodynamic activity of azithromycin against macrolide-susceptible and -resistant Streptococcus pneumoniae simulating clinically achievable free serum, epithelial lining fluid and middle ear fluid concentrations. | 2003 | J. Antimicrob. Chemother. | pmid:12775677 |
| Blandford JM and Gift TL | The cost-effectiveness of single-dose azithromycin for treatment of incubating syphilis. | 2003 | Sex Transm Dis | pmid:12782951 |
| Abdelghaffar H et al. | Interaction of macrolides and ketolides with the phagocytic cell line PLB-985. | 2003 | J Chemother | pmid:12962363 |
| Miguel L and Barbas C | LC determination of impurities in azithromycin tablets. | 2003 | J Pharm Biomed Anal | pmid:12972086 |
| Sirinavin S et al. | Norfloxacin and azithromycin for treatment of nontyphoidal salmonella carriers. | 2003 | Clin. Infect. Dis. | pmid:12942401 |
| Matsuzaki K et al. | [Susceptibility of major pathogens of acute pharyngitis and tonsillitis to levofloxacin and other oral antimicrobial drugs]. | 2003 | Jpn J Antibiot | pmid:12942788 |
| DeÄŸerli K et al. | Efficacy of azithromycin in a murine toxoplasmosis model, employing a Toxoplasma gondii strain from Turkey. | 2003 | Acta Trop. | pmid:12943976 |
| Zhou WQ et al. | [Clinic efficacy of treating chronic prostatitis caused by Neisseria gonorrhoeae with azithromycin aspartic-acid injection]. | 2003 | Zhonghua Nan Ke Xue | pmid:12680331 |
| Sicklinger M et al. | In vitro susceptibility testing of four antibiotics against Borrelia burgdorferi: a comparison of results for the three genospecies Borrelia afzelii, Borrelia garinii, and Borrelia burgdorferi sensu stricto. | 2003 | J. Clin. Microbiol. | pmid:12682190 |
| Karlowsky JA et al. | Factors associated with relative rates of antimicrobial resistance among Streptococcus pneumoniae in the United States: results from the TRUST Surveillance Program (1998-2002). | 2003 | Clin. Infect. Dis. | pmid:12684907 |
| Hamdan II | Comparative in vitro investigations of the interaction between some macrolides and Cu(II), Zn(II) and Fe(II). | 2003 | Pharmazie | pmid:12685822 |
| Llor Vilà C | [I'd rather give azithromycin for three days. That way the patient complies]. | 2003 | Aten Primaria | pmid:12735886 |
| Gaynor BD et al. | Eliminating trachoma in areas with limited disease. | 2003 | Emerging Infect. Dis. | pmid:12737745 |
| Ito K et al. | Prediction of the in vivo interaction between midazolam and macrolides based on in vitro studies using human liver microsomes. | 2003 | Drug Metab. Dispos. | pmid:12814973 |
| Woods GL et al. | Multisite reproducibility of results obtained by two broth dilution methods for susceptibility testing of Mycobacterium avium complex. | 2003 | J. Clin. Microbiol. | pmid:12574258 |