Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

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Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Abnormalities, Drug-Induced D000014 10 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Abscess D000038 13 associated lipids
Achondroplasia D000130 1 associated lipids
Acinetobacter Infections D000151 4 associated lipids
Acne Vulgaris D000152 35 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Actinomycetales Infections D000193 4 associated lipids
Agammaglobulinemia D000361 4 associated lipids
Airway Obstruction D000402 13 associated lipids
Amebiasis D000562 2 associated lipids
Anaphylaxis D000707 35 associated lipids
Anaplasmataceae Infections D000711 3 associated lipids
Angina, Unstable D000789 14 associated lipids
Aphasia, Broca D001039 1 associated lipids
Arteriosclerosis D001161 86 associated lipids
Arthritis D001168 41 associated lipids
Arthritis, Infectious D001170 8 associated lipids
Bacterial Infections D001424 21 associated lipids
Bartonella Infections D001474 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Vajpayee S et al. Scrub typhus causing neonatal hepatitis with acute liver failure-A case series. 2017 Indian J Gastroenterol pmid:28612320
Tsubouchi K et al. Azithromycin attenuates myofibroblast differentiation and lung fibrosis development through proteasomal degradation of NOX4. 2017 Autophagy pmid:28613983
Sanders AM et al. Burden of trachoma in five counties of Eastern Equatoria state, South Sudan: Results from population-based surveys. 2017 PLoS Negl Trop Dis pmid:28614375
Turner KM et al. Analysis of the potential for point-of-care test to enable individualised treatment of infections caused by antimicrobial-resistant and susceptible strains of : a modelling study. 2017 BMJ Open pmid:28615273
Nozawa H et al. Pertussis without apparent cough in a disabled girl with a tracheostomy. 2017 J. Infect. Chemother. pmid:28623110
Kirk SK et al. Efficacy of Azithromycin and Compounded Atovaquone for Treatment of Babesia gibsoni in Dogs. 2017 J. Vet. Intern. Med. pmid:28625019
Kawamura K et al. Azithromycin for idiopathic acute exacerbation of idiopathic pulmonary fibrosis: a retrospective single-center study. 2017 BMC Pulm Med pmid:28629448
Wang Y et al. Synthesis and antibacterial activity of novel 4″-O-(1-aralkyl-1,2,3-triazol-4-methyl-carbamoyl) azithromycin analogs. 2017 Bioorg. Med. Chem. Lett. pmid:28655423
Lendermon EA et al. Azithromycin decreases NALP3 mRNA stability in monocytes to limit inflammasome-dependent inflammation. 2017 Respir. Res. pmid:28659178
Yazdanbakhsh AR et al. Reduction of non-Betalactam Antibiotics COD by Combined Coagulation and Advanced Oxidation Processes. 2016 Water Environ. Res. pmid:28661328
West SK et al. Treating village newcomers and travelers for trachoma: Results from ASANTE cluster randomized trial. 2017 PLoS ONE pmid:28662043
Xiao Z et al. Comparison of the ameliorative effects of Qingfei Tongluo formula and azithromycin on Mycoplasma pneumoniae pneumonia. 2017 J Nat Med pmid:28664473
Koetsveld J et al. Susceptibility of the Relapsing-Fever Spirochete Borrelia miyamotoi to Antimicrobial Agents. 2017 Antimicrob. Agents Chemother. pmid:28674060
Molefe NI et al. Oral administration of azithromycin ameliorates trypanosomosis in Trypanosoma congolense-infected mice. 2017 Parasitol. Res. pmid:28674747
Balci O and Gulkilik G Assessment of efficacy of topical azithromycin 1.5 per cent ophthalmic solution for the treatment of meibomian gland dysfunction. 2018 Clin Exp Optom pmid:28677153
Paul P et al. Capillary electrophoresis with capacitively coupled contactless conductivity detection method development and validation for the determination of azithromycin, clarithromycin, and clindamycin. 2017 J Sep Sci pmid:28683179
Fan LC et al. Macrolides protect against infection via inhibition of inflammasomes. 2017 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:28684545
Brusselle G and Pavord I Azithromycin in uncontrolled asthma. 2017 Lancet pmid:28687412
Gibson PG et al. Effect of azithromycin on asthma exacerbations and quality of life in adults with persistent uncontrolled asthma (AMAZES): a randomised, double-blind, placebo-controlled trial. 2017 Lancet pmid:28687413
Harper LM et al. Economic Evaluation of Adjunctive Azithromycin Prophylaxis for Cesarean Delivery. 2017 Obstet Gynecol pmid:28697108
Barberá MJ et al. Mycoplasma genitalium Macrolide and Fluoroquinolone Resistance: Prevalence and Risk Factors Among a 2013-2014 Cohort of Patients in Barcelona, Spain. 2017 Sex Transm Dis pmid:28703723
Horner P et al. Which azithromycin regimen should be used for treating ? A meta-analysis. 2018 Sex Transm Infect pmid:28717050
Stoney RJ et al. Travelers' Diarrhea and Other Gastrointestinal Symptoms Among Boston-Area International Travelers. 2017 Am. J. Trop. Med. Hyg. pmid:28719282
O'Brien KS et al. Mass Azithromycin and Malaria Parasitemia in Niger: Results from a Community-Randomized Trial. 2017 Am. J. Trop. Med. Hyg. pmid:28722569
Bloch EM et al. Antibiotic Resistance in Young Children in Kilosa District, Tanzania 4 Years after Mass Distribution of Azithromycin for Trachoma Control. 2017 Am. J. Trop. Med. Hyg. pmid:28722638
Zhao L et al. Trends in antimicrobial resistance in Neisseria gonorrhoeae and molecular characteristics of N. gonorrhoeae with decreased susceptibility to ceftriaxone in Shandong, China, 2007 to 2014. 2018 Int. J. Antimicrob. Agents pmid:28729124
McConnell K and Shields M Azithromycin for episodes with asthma-like symptoms in young children aged 1-3 years. 2017 Arch Dis Child Educ Pract Ed pmid:28735295
Subedi Y Around Manaslu Ultramarathon: Diarrhea Is Still the King. 2017 Wilderness Environ Med pmid:28735656
Li Y et al. Synergistic Activity of Berberine with Azithromycin against Pseudomonas Aeruginosa Isolated from Patients with Cystic Fibrosis of Lung In Vitro and In Vivo. 2017 Cell. Physiol. Biochem. pmid:28738346
Li R et al. Effects of oral florfenicol and azithromycin on gut microbiota and adipogenesis in mice. 2017 PLoS ONE pmid:28742883
Fleming-Dutra KE et al. Variations in Antibiotic and Azithromycin Prescribing for Children by Geography and Specialty-United States, 2013. 2018 Pediatr. Infect. Dis. J. pmid:28746259
Tada H et al. The effects of Lactobacillus reuteri probiotics combined with azithromycin on peri-implantitis: A randomized placebo-controlled study. 2018 J Prosthodont Res pmid:28756115
Casas-Maldonado F Bronchiectasis and Azithromycin. 2018 Arch. Bronconeumol. pmid:28757281
Upadhyay K et al. Combination therapy with ampicillin and azithromycin improved outcomes in a mouse model of group B streptococcal sepsis. 2017 PLoS ONE pmid:28759625
Gifford J et al. Decision support during electronic prescription to stem antibiotic overuse for acute respiratory infections: a long-term, quasi-experimental study. 2017 BMC Infect. Dis. pmid:28760143
Mandhane PJ et al. Treatment of preschool children presenting to the emergency department with wheeze with azithromycin: A placebo-controlled randomized trial. 2017 PLoS ONE pmid:28771627
Hoogewoud F et al. Prognostic Factors in Syphilitic Uveitis. 2017 Ophthalmology pmid:28779905
Bergeron A et al. Effect of Azithromycin on Airflow Decline-Free Survival After Allogeneic Hematopoietic Stem Cell Transplant: The ALLOZITHRO Randomized Clinical Trial. 2017 JAMA pmid:28787506
Fage C et al. The combination of oseltamivir with azithromycin does not show additional benefits over oseltamivir monotherapy in mice infected with influenza A(H1N1)pdm2009 virus. 2017 J. Med. Virol. pmid:28792077
Benn K et al. Bradycardia and Hypothermia Complicating Azithromycin Treatment. 2017 Am J Case Rep pmid:28798290
Ribeiro M et al. Azithromycin treatment is able to control the infection by two genotypes of Toxoplasma gondii in human trophoblast BeWo cells. 2017 Exp. Parasitol. pmid:28803905
Whiley DM et al. Molecular Antimicrobial Resistance Surveillance for Neisseria gonorrhoeae, Northern Territory, Australia. 2017 Emerging Infect. Dis. pmid:28820128
Yoon HY et al. Clinical significance of QT-prolonging drug use in patients with MDR-TB or NTM disease. 2017 Int. J. Tuberc. Lung Dis. pmid:28826448
Hallström H et al. Open flap debridement of peri-implantitis with or without adjunctive systemic antibiotics: A randomized clinical trial. 2017 J. Clin. Periodontol. pmid:28836279
Gaydos CA Mycoplasma genitalium: Accurate Diagnosis Is Necessary for Adequate Treatment. 2017 J. Infect. Dis. pmid:28838072
Bradshaw CS et al. New Horizons in Mycoplasma genitalium Treatment. 2017 J. Infect. Dis. pmid:28838073
Horner PJ and Martin DH Mycoplasma genitalium Infection in Men. 2017 J. Infect. Dis. pmid:28838074
Iannetta M et al. Azithromycin Shows Anti-Zika Virus Activity in Human Glial Cells. 2017 Antimicrob. Agents Chemother. pmid:28839081
Saiz JC and Martín-Acebes MA Reply to Iannetta et al., "Azithromycin Shows Anti-Zika Virus Activity in Human Glial Cells". 2017 Antimicrob. Agents Chemother. pmid:28839084
Seyama S et al. Amino Acid Substitution in the Major Multidrug Efflux Transporter Protein AcrB Contributes to Low Susceptibility to Azithromycin in Haemophilus influenzae. 2017 Antimicrob. Agents Chemother. pmid:28848006
Xue Y et al. An in vitro model of azithromycin-induced persistent Chlamydia trachomatis infection. 2017 FEMS Microbiol. Lett. pmid:28854672
Asano N et al. Limited Azithromycin Localization to Rabbit Meibomian Glands Revealed by LC-MS-Based Bioanalysis and DESI Imaging. 2017 Biol. Pharm. Bull. pmid:28867744
Lee SC et al. Comparative effectiveness of azithromycin for treating scrub typhus: A PRISMA-compliant systematic review and meta-analysis. 2017 Medicine (Baltimore) pmid:28885357
Tribble DR Antibiotic Therapy for Acute Watery Diarrhea and Dysentery. 2017 Mil Med pmid:28885920
Ito A et al. A Case of Community-Acquired Pneumonia Due to Legionella pneumophila Serogroup 9 Wherein Initial Treatment with Single-Dose Oral Azithromycin Appeared Useful. 2017 Jpn. J. Infect. Dis. pmid:28890505
Cole MJ et al. Overall Low Extended-Spectrum Cephalosporin Resistance but high Azithromycin Resistance in Neisseria gonorrhoeae in 24 European Countries, 2015. 2017 BMC Infect. Dis. pmid:28893203
Trembizki E et al. High levels of macrolide-resistant Mycoplasma genitalium in Queensland, Australia. 2017 J. Med. Microbiol. pmid:28893363
Jacobsson S et al. Activity of the Novel Pleuromutilin Lefamulin (BC-3781) and Effect of Efflux Pump Inactivation on Multidrug-Resistant and Extensively Drug-Resistant Neisseria gonorrhoeae. 2017 Antimicrob. Agents Chemother. pmid:28893785
Wang R et al. IncA/C plasmids conferring high azithromycin resistance in vibrio cholerae. 2018 Int. J. Antimicrob. Agents pmid:28919196
Srivastava S et al. Failure of the azithromycin and ethambutol combination regimen in the hollow-fibre system model of pulmonary Mycobacterium avium infection is due to acquired resistance. 2017 J. Antimicrob. Chemother. pmid:28922805
Srivastava S et al. A 'shock and awe' thioridazine and moxifloxacin combination-based regimen for pulmonary Mycobacterium avium-intracellulare complex disease. 2017 J. Antimicrob. Chemother. pmid:28922810
Koeva M et al. An Antipersister Strategy for Treatment of Chronic Pseudomonas aeruginosa Infections. 2017 Antimicrob. Agents Chemother. pmid:28923873
Cluver C et al. Interventions for treating genital Chlamydia trachomatis infection in pregnancy. 2017 Cochrane Database Syst Rev pmid:28937705
Glanternik JR et al. A Cluster of Cases of Babesia microti Among Neonates Traced to a Single Unit of Donor Blood. 2018 Pediatr. Infect. Dis. J. pmid:28945680
Bogdan M et al. In vitro effect of subminimal inhibitory concentrations of antibiotics on the biofilm formation ability of Acinetobacter baumannii clinical isolates. 2018 J Chemother pmid:28956494
Brown JD et al. Shigella species epidemiology and antimicrobial susceptibility: the implications of emerging azithromycin resistance for guiding treatment, guidelines and breakpoints. 2017 J. Antimicrob. Chemother. pmid:28961759
Atkinson CT et al. Expression of acquired macrolide resistance genes in Haemophilus influenzae. 2017 J. Antimicrob. Chemother. pmid:28961896
Li B et al. The efficacy of azithromycin and doxycycline treatment for rectal chlamydial infection: a retrospective cohort study in South Australia. 2018 Intern Med J pmid:28967178
Tuite AR et al. Impact of Rapid Susceptibility Testing and Antibiotic Selection Strategy on the Emergence and Spread of Antibiotic Resistance in Gonorrhea. 2017 J. Infect. Dis. pmid:28968710
Pokharel S et al. Co-trimoxazole versus azithromycin for the treatment of undifferentiated febrile illness in Nepal: study protocol for a randomized controlled trial. 2017 Trials pmid:28969659
Lee S et al. The therapeutic efficacy of azithromycin and nitazoxanide in the acute pig model of Cryptosporidium hominis. 2017 PLoS ONE pmid:28973041
Senilă S et al. Infliximab-induced acne and acute localized exanthematous pustulosis: Case report. 2017 Dermatol Ther pmid:28976720
Liu D et al. Mycoplasma-associated multidrug resistance of hepatocarcinoma cells requires the interaction of P37 and Annexin A2. 2017 PLoS ONE pmid:28976984
Alchakaki A et al. Which patients with respiratory disease need long-term azithromycin? 2017 Cleve Clin J Med pmid:28985171
Lu Y et al. Antibiotics Promote Escherichia coli-Pseudomonas aeruginosa Conjugation through Inhibiting Quorum Sensing. 2017 Antimicrob. Agents Chemother. pmid:28993333
González-Beiras C et al. Single-Dose Azithromycin for the Treatment of Haemophilus ducreyi Skin Ulcers in Papua New Guinea. 2017 Clin. Infect. Dis. pmid:29020192
Riddle MS et al. Trial Evaluating Ambulatory Therapy of Travelers' Diarrhea (TrEAT TD) Study: A Randomized Controlled Trial Comparing 3 Single-Dose Antibiotic Regimens With Loperamide. 2017 Clin. Infect. Dis. pmid:29029033
Thakur SD et al. High levels of susceptibility to new and older antibiotics in Neisseria gonorrhoeae isolates from Saskatchewan (2003-15): time to consider point-of-care or molecular testing for precision treatment? 2018 J. Antimicrob. Chemother. pmid:29029217
Vermillion Maier ML and Tjeerdema RS Azithromycin sorption and biodegradation in a simulated California river system. 2018 Chemosphere pmid:29031188
Karhu E et al. Identification of Privileged Antichlamydial Natural Products by a Ligand-Based Strategy. 2017 J. Nat. Prod. pmid:29043803
Stanbrook MB Azithromycin reduced exacerbations and improved QoL in symptomatic asthma despite inhaled maintenance therapy. 2017 Ann. Intern. Med. pmid:29049761
Giguère S et al. Antimicrobial Resistance in . 2017 Microbiol Spectr pmid:29052538
Terkelsen D et al. Multidrug-resistant infection with ceftriaxone resistance and intermediate resistance to azithromycin, Denmark, 2017. 2017 Euro Surveill. pmid:29067905
Chatterjee S and Agrawal D Azithromycin in the Management of Pythium insidiosum Keratitis. 2018 Cornea pmid:29095755
Emmanuel R et al. Antimicrobial efficacy of drug blended biosynthesized colloidal gold nanoparticles from Justicia glauca against oral pathogens: A nanoantibiotic approach. 2017 Microb. Pathog. pmid:29101061
Mitjà O et al. Effectiveness of single-dose azithromycin to treat latent yaws: a longitudinal comparative cohort study. 2017 Lancet Glob Health pmid:29107621
Marks M and Mabey D Single-dose azithromycin to treat latent yaws. 2017 Lancet Glob Health pmid:29107622
Skeith AE et al. Adding Azithromycin to Cephalosporin for Cesarean Delivery Infection Prophylaxis: A Cost-Effectiveness Analysis. 2017 Obstet Gynecol pmid:29112658
Pan H and Ba-Thein W Diagnostic Accuracy of Global Pharma Health Fund Minilabâ„¢ in Assessing Pharmacopoeial Quality of Antimicrobials. 2018 Am. J. Trop. Med. Hyg. pmid:29141717
Rasmussen LD et al. Follicular bronchiolitis in an HIV-infected individual on combination antiretroviral therapy with low CD4+ cell count but sustained viral suppression. 2017 BMJ Case Rep pmid:29191821
Castelli G et al. PURLs: Does azithromycin have a role in cesarean sections? 2017 J Fam Pract pmid:29202146
Wang CM et al. Synthesis and Antibacterial Evaluation of a Series of 11,12-Cyclic Carbonate Azithromycin-3-O-descladinosyl-3-O-carbamoyl Glycosyl Derivatives. 2017 Molecules pmid:29207567
Dolezelova E et al. Resveratrol modifies biliary secretion of cholephilic compounds in sham-operated and cholestatic rats. 2017 World J. Gastroenterol. pmid:29209109
Medeiros PHQS et al. Molecular characterization of virulence and antimicrobial resistance profile of Shigella species isolated from children with moderate to severe diarrhea in northeastern Brazil. 2018 Diagn. Microbiol. Infect. Dis. pmid:29217418
Papp JR et al. Accuracy and reproducibility of the Etest to detect drug-resistant Neisseria gonorrhoeae to contemporary treatment. 2018 J. Med. Microbiol. pmid:29219803
Romero L et al. Macrolides for treatment of Haemophilus ducreyi infection in sexually active adults. 2017 Cochrane Database Syst Rev pmid:29226307
Sanchez Garcia D et al. Cellular accumulation and lipid binding of perfluorinated alkylated substances (PFASs) - A comparison with lysosomotropic drugs. 2018 Chem. Biol. Interact. pmid:29248446
Oldenburg CE et al. Comparison of Mass Azithromycin Coverage Targets of Children in Niger: A Cluster-Randomized Trachoma Trial. 2018 Am. J. Trop. Med. Hyg. pmid:29260659
Mascarenhas TR et al. Tick-borne illness after transplantation: Case and review. 2018 Transpl Infect Dis pmid:29277955
Fuji S Azithromycin and Survival After Hematopoietic Stem Cell Transplant. 2017 JAMA pmid:29279920