Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Abnormalities, Drug-Induced D000014 10 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Abscess D000038 13 associated lipids
Achondroplasia D000130 1 associated lipids
Acinetobacter Infections D000151 4 associated lipids
Acne Vulgaris D000152 35 associated lipids
Acquired Immunodeficiency Syndrome D000163 12 associated lipids
Actinomycetales Infections D000193 4 associated lipids
Agammaglobulinemia D000361 4 associated lipids
Airway Obstruction D000402 13 associated lipids
Amebiasis D000562 2 associated lipids
Anaphylaxis D000707 35 associated lipids
Anaplasmataceae Infections D000711 3 associated lipids
Angina, Unstable D000789 14 associated lipids
Aphasia, Broca D001039 1 associated lipids
Arteriosclerosis D001161 86 associated lipids
Arthritis D001168 41 associated lipids
Arthritis, Infectious D001170 8 associated lipids
Bacterial Infections D001424 21 associated lipids
Bartonella Infections D001474 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

Download all related citations
Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Yazdanbakhsh AR et al. Reduction of non-Betalactam Antibiotics COD by Combined Coagulation and Advanced Oxidation Processes. 2016 Water Environ. Res. pmid:28661328
Liao YS et al. Azithromycin-Nonsusceptible Shigella flexneri 3a in Men Who Have Sex with Men, Taiwan, 2015-2016. 2016 Emerging Infect. Dis. pmid:28098533
Gawin A et al. Mildly pruritic palmar rash. 2016 J Fam Pract pmid:28087868
Berkowitz ST et al. Resolution of spontaneous hemoabdomen secondary to peliosis hepatis following surgery and azithromycin treatment in a Bartonella species infected dog. 2016 J Vet Emerg Crit Care (San Antonio) pmid:27074964
Martín JM et al. Azithromycin for the Treatment of Ciclosporin-Induced Gingival Hyperplasia. 2016 Actas Dermosifiliogr pmid:26996332
Petrelli F et al. Poly(ADP-ribose) polymerase is not involved in the neuroprotection exerted by azithromycin against ischemic stroke in mice. 2016 Eur. J. Pharmacol. pmid:27663279
Gerhardt P et al. [Male urethritis]. 2016 Ann Dermatol Venereol pmid:27776813
O'Farrell N Control of gonorrhoea and chlamydia in the UK. 2016 Lancet pmid:27477165
Zhu XH et al. Viral and Bacterial Etiology of Acute Diarrhea among Children under 5 Years of Age in Wuhan, China. 2016 Chin. Med. J. pmid:27503019
Zhao M et al. Comparison of minocycline and azithromycin for the treatment of mild scrub typhus in northern China. 2016 Int. J. Antimicrob. Agents pmid:27449540
Dukers-Muijrers NH et al. Design of the FemCure study: prospective multicentre study on the transmission of genital and extra-genital Chlamydia trachomatis infections in women receiving routine care. 2016 BMC Infect. Dis. pmid:27502928
Huang SW et al. Azithromycin impairs TLR7 signaling in dendritic cells and improves the severity of imiquimod-induced psoriasis-like skin inflammation in mice. 2016 J. Dermatol. Sci. pmid:27449383
Yoshioka D et al. Efficacy of β-Lactam-plus-Macrolide Combination Therapy in a Mouse Model of Lethal Pneumococcal Pneumonia. 2016 Antimicrob. Agents Chemother. pmid:27480866
Jacobsson S et al. WGS analysis and molecular resistance mechanisms of azithromycin-resistant (MIC >2 mg/L) Neisseria gonorrhoeae isolates in Europe from 2009 to 2014. 2016 J. Antimicrob. Chemother. pmid:27432597
Jeong BH et al. Peak Plasma Concentration of Azithromycin and Treatment Responses in Mycobacterium avium Complex Lung Disease. 2016 Antimicrob. Agents Chemother. pmid:27480854
de Zwart L et al. Ibrutinib Dosing Strategies Based on Interaction Potential of CYP3A4 Perpetrators Using Physiologically Based Pharmacokinetic Modeling. 2016 Clin. Pharmacol. Ther. pmid:27367453
Abeles SR et al. Microbial diversity in individuals and their household contacts following typical antibiotic courses. 2016 Microbiome pmid:27473422
Lockington D Oral azithromycin and blepharitis: symptoms and signs improve, so where are the publications? 2016 Clin. Experiment. Ophthalmol. pmid:27356302
Ramaiah B et al. High azithromycin concentration in lungs by way of bovine serum albumin microspheres as targeted drug delivery: lung targeting efficiency in albino mice. 2016 Daru pmid:27150818
Rajabi O et al. Topical liposomal azithromycin in the treatment of acute cutaneous leishmaniasis. 2016 Dermatol Ther pmid:27073044
Geisler WM et al. Azithromycin versus Doxycycline for Chlamydia. 2016 N. Engl. J. Med. pmid:27144856
Dunn AL et al. Naegleria fowleri That Induces Primary Amoebic Meningoencephalitis: Rapid Diagnosis and Rare Case of Survival in a 12-Year-Old Caucasian Girl. 2016 Lab Med pmid:26984830
Yelenich-Huss MJ et al. Ozena in Immigrants of Differing Backgrounds. 2016 Am. J. Trop. Med. Hyg. pmid:27114295
Saini H et al. Antimicrobial and antifouling efficacy of urinary catheters impregnated with a combination of macrolide and fluoroquinolone antibiotics against Pseudomonas aeruginosa. 2016 Biofouling pmid:26982572
Vermeersch K et al. The Belgian trial with azithromycin for acute COPD exacerbations requiring hospitalization: an investigator-initiated study protocol for a multicenter, randomized, double-blind, placebo-controlled trial. 2016 Int J Chron Obstruct Pulmon Dis pmid:27099485
Levy V et al. A Case of Persistent and Possibly Treatment Resistant Pharyngeal Gonorrhea. 2016 Sex Transm Dis pmid:26967304
Guo Y et al. Chlamydiaphage φCPG1 Capsid Protein Vp1 Inhibits Chlamydia trachomatis Growth via the Mitogen-Activated Protein Kinase Pathway. 2016 Viruses pmid:27089359
Gülses A and Ayna M Re: Comparison of Azithromycin and Amoxicillin Before Dental Implant Placement: An Exploratory Study of Bioavailability and Resolution of Postoperative Inflammation. 2016 J. Periodontol. pmid:26962889
McClure KS and Cameron ST An audit of expedited treatment for uncomplicated Chlamydia trachomatis index cases at the community pharmacy. 2016 Int J STD AIDS pmid:26945591
Lee H et al. New treatment options for infections caused by increasingly antimicrobial-resistant Neisseria gonorrhoeae. 2016 Expert Rev Anti Infect Ther pmid:26690658
Nakajima T et al. Microbiological and Clinical Effects of Sitafloxacin and Azithromycin in Periodontitis Patients Receiving Supportive Periodontal Therapy. 2016 Antimicrob. Agents Chemother. pmid:26729495
Jentsch HF et al. Nonsurgical therapy of chronic periodontitis with adjunctive systemic azithromycin or amoxicillin/metronidazole. 2016 Clin Oral Investig pmid:26685849
Slade J et al. Chlamydial Pre-Infection Protects from Subsequent Herpes Simplex Virus-2 Challenge in a Murine Vaginal Super-Infection Model. 2016 PLoS ONE pmid:26726882
Lococo F et al. Hemoptysis and Progressive Dyspnea in a 67-Year-Old Woman with History of Renal Transplantation. 2016 Am. J. Respir. Crit. Care Med. pmid:26681504
Mukai S et al. Macrolides sensitize EGFR-TKI-induced non-apoptotic cell death via blocking autophagy flux in pancreatic cancer cell lines. 2016 Int. J. Oncol. pmid:26718641
Miyagawa T et al. Azithromycin recovers reductions in barrier function in human gingival epithelial cells stimulated with tumor necrosis factor-α. 2016 Arch. Oral Biol. pmid:26655749
Smith DJ et al. Pseudomonas aeruginosa antibiotic resistance in Australian cystic fibrosis centres. 2016 Respirology pmid:26711802
Lübbert C Antimicrobial therapy of acute diarrhoea: a clinical review. 2016 Expert Rev Anti Infect Ther pmid:26641310
Lee SJ et al. Maternal azithromycin administration eradicates intra-amniotic Ureaplasma infection: The first human case report. 2016 J Obstet Gynaecol pmid:26634623
Martin I et al. Decline in Decreased Cephalosporin Susceptibility and Increase in Azithromycin Resistance in Neisseria gonorrhoeae, Canada. 2016 Emerging Infect. Dis. pmid:26689114
Luo Q et al. Surface plasmon resonance sensor for antibiotics detection based on photo-initiated polymerization molecularly imprinted array. 2016 Talanta pmid:27769483
Unger HW et al. Azithromycin-containing intermittent preventive treatment in pregnancy affects gestational weight gain, an important predictor of birthweight in Papua New Guinea - an exploratory analysis. 2016 Matern Child Nutr pmid:26373537
Zhang Z et al. Clinical effect of azithromycin as an adjunct to non-surgical treatment of chronic periodontitis: a meta-analysis of randomized controlled clinical trials. 2016 J. Periodont. Res. pmid:26362529
Chang Y et al. Factors Influencing the HPLC Determination for Related Substances of Azithromycin. 2016 J Chromatogr Sci pmid:26324196
Steeples LR et al. Real-time PCR using the 529 bp repeat element for the diagnosis of atypical ocular toxoplasmosis. 2016 Br J Ophthalmol pmid:26174811
Arora N et al. Origin of modern syphilis and emergence of a pandemic Treponema pallidum cluster. 2016 Nat Microbiol pmid:27918528
Retallack H et al. Zika virus cell tropism in the developing human brain and inhibition by azithromycin. 2016 Proc. Natl. Acad. Sci. U.S.A. pmid:27911847
Brittain C et al. Gentamicin versus ceftriaxone for the treatment of gonorrhoea (G-TOG trial): study protocol for a randomised trial. 2016 Trials pmid:27881151
Libois A and De Wit S Which empiric syndromic treatment for urethritis? 2016 Int J STD AIDS pmid:27794143
Gaudreau C et al. Shigella flexneri with Ciprofloxacin Resistance and Reduced Azithromycin Susceptibility, Canada, 2015. 2016 Emerging Infect. Dis. pmid:27767915