Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Shigemura K et al. | Azithromycin resistance and its mechanism in Neisseria gonorrhoeae strains in Hyogo, Japan. | 2015 | Antimicrob. Agents Chemother. | pmid:25712352 |
| Mitjà O et al. | Mass treatment with single-dose azithromycin for yaws. | 2015 | N. Engl. J. Med. | pmid:25693010 |
| Singh N et al. | Cat-scratch fever and lymphadenopathy in a rheumatoid arthritis patient on tocilizumab. | 2015 | J Clin Rheumatol | pmid:25539435 |
| Bissessor M et al. | Macrolide resistance and azithromycin failure in a Mycoplasma genitalium-infected cohort and response of azithromycin failures to alternative antibiotic regimens. | 2015 | Clin. Infect. Dis. | pmid:25537875 |
| Kapil R et al. | Investigating the epidemiology of repeat Chlamydia trachomatis detection after treatment by using C. trachomatis OmpA genotyping. | 2015 | J. Clin. Microbiol. | pmid:25472488 |
| Vora GK et al. | Conjunctival pseudotumor caused by herpes simplex virus infection. | 2015 | JAMA Ophthalmol | pmid:25232655 |
| Wan YF et al. | Azithromycin attenuates pulmonary inflammation and emphysema in smoking-induced COPD model in rats. | 2015 | Respir Care | pmid:25249648 |
| Quinn TC and Gaydos CA | Treatment for Chlamydia Infection--Doxycycline versus Azithromycin. | 2015 | N. Engl. J. Med. | pmid:26699174 |
| Marks M et al. | Challenges and key research questions for yaws eradication. | 2015 | Lancet Infect Dis | pmid:26362174 |
| Muralidharan V and Striepen B | Teaching old drugs new tricks to stop malaria invasion in its tracks. | 2015 | BMC Biol. | pmid:26349580 |
| Fifer H et al. | Gonorrhoea treatment position statement. | 2015 | Sex Transm Infect | pmid:26195472 |
| Arnež M and Ružić-Sabljić E | Azithromycin Is Equally Effective as Amoxicillin in Children with Solitary Erythema Migrans. | 2015 | Pediatr. Infect. Dis. J. | pmid:26186104 |
| Lu H et al. | High frequency of the 23S rRNA A2058G mutation of Treponema pallidum in Shanghai is associated with a current strategy for the treatment of syphilis. | 2015 | Emerg Microbes Infect | pmid:26038763 |
| Washington AZ et al. | Exploiting translational stalling peptides in an effort to extend azithromycin interaction within the prokaryotic ribosome nascent peptide exit tunnel. | 2015 | Bioorg. Med. Chem. | pmid:26037612 |
| Schreeg ME et al. | Rapid High-Resolution Melt Analysis of Cytauxzoon felis Cytochrome b To Aid in the Prognosis of Cytauxzoonosis. | 2015 | J. Clin. Microbiol. | pmid:26019197 |
| Chazan B et al. | Susceptibility of Group A Streptococcus to Antimicrobial Agents in Northern Israel: A Surveillance Study. | 2015 | Microb. Drug Resist. | pmid:26430943 |
| Lynagh Y et al. | Detailed characterization of the first high-level azithromycin-resistant Neisseria gonorrhoeae cases in Ireland. | 2015 | J. Antimicrob. Chemother. | pmid:25907073 |
| Choi AH et al. | Clinicocytopathologic correlation in an atypical presentation of lymphadenopathy with review of literature. | 2015 | Am. J. Clin. Pathol. | pmid:25873511 |
| Riesselman A and El-Mallakh RS | Akathisia with azithromycin. | 2015 | Ann Pharmacother | pmid:25870444 |
| He X et al. | Synergistic combination of marine oligosaccharides and azithromycin against Pseudomonas aeruginosa. | 2014 Sep-Oct | Microbiol. Res. | pmid:24529598 |
| Rai S | Azithromycin zone interpretation for Salmonella: time to adopt BSAC's zone diameters? | 2014 Oct-Dec | Indian J Med Microbiol | pmid:25297045 |
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| Rajaii RM et al. | Acute generalized exanthematous pustulosis reported due to loxosceles envenomation may be secondary to azithromycin therapy. | 2014 May-Jun | Mo Med | pmid:25011333 |
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| Pandhi D et al. | The efficacy of azithromycin in pityriasis rosea: a randomized, double-blind, placebo-controlled trial. | 2014 Jan-Feb | Indian J Dermatol Venereol Leprol | pmid:24448121 |
| Lis G et al. | Add-on treatment with nebulized hypertonic saline in a child with plastic bronchitis after the Glenn procedure. | 2014 Jan-Feb | J Bras Pneumol | pmid:24626275 |
| Lahra MM | Australian gonococcal surveillance programme, 1 April to 30 June 2014. | 2014 | Commun Dis Intell Q Rep | pmid:25631604 |
| Dumke R et al. | Molecular characterization of macrolide resistance of a Mycoplasma pneumoniae strain that developed during therapy of a patient with pneumonia. | 2014 | Int. J. Infect. Dis. | pmid:25449256 |
| Sagara I et al. | Efficacy and safety of a combination of azithromycin and chloroquine for the treatment of uncomplicated Plasmodium falciparum malaria in two multi-country randomised clinical trials in African adults. | 2014 | Malar. J. | pmid:25425434 |
| van Bijnen EM et al. | Primary care treatment guidelines for skin infections in Europe: congruence with antimicrobial resistance found in commensal Staphylococcus aureus in the community. | 2014 | BMC Fam Pract | pmid:25413920 |
| Cole MJ et al. | Emerging cephalosporin and multidrug-resistant gonorrhoea in Europe. | 2014 | Euro Surveill. | pmid:25411689 |
| Khoshnood A et al. | Replacement of clarithromycin with azithromycin in triple therapy regimens for the eradication of Helicobacter pylori: A randomized clinical trial. | 2014 | J Med Life | pmid:25408735 |
| Burr SE et al. | Anthropometric indices of Gambian children after one or three annual rounds of mass drug administration with azithromycin for trachoma control. | 2014 | BMC Public Health | pmid:25407464 |
| Beyda RM et al. | Azithromycin efficacy in the treatment of Chlamydia trachomatis among detained youth. | 2014 | Sex Transm Dis | pmid:25211253 |
| Zhong M et al. | Azithromycin cationic non-lecithoid nano/microparticles improve bioavailability and targeting efficiency. | 2014 | Pharm. Res. | pmid:25208873 |
| Nambudiri VE | More than skin deep--the costs of antibiotic overuse: a teachable moment. | 2014 | JAMA Intern Med | pmid:25178174 |
| Filist M et al. | Simplified LC-MS/MS method enabling the determination of azithromycin in human plasma after a low 100mg dose administration. | 2014 | J Pharm Biomed Anal | pmid:25168217 |
| Schuhfried G et al. | Gilles de la Tourette Syndrome caused by Mycoplasma pneumoniae successfully treated with macrolides. | 2014 | Klin Padiatr | pmid:25153913 |
| de Barsy M et al. | Antibiotic susceptibility of Estrella lausannensis, a potential emerging pathogen. | 2014 | Microbes Infect. | pmid:25150688 |
| Sundaramurthi P and Suryanarayanan R | Azithromycin hydrates-implications of processing-induced phase transformations. | 2014 | J Pharm Sci | pmid:25139082 |
| Gao D et al. | Optimal seasonal timing of oral azithromycin for malaria. | 2014 | Am. J. Trop. Med. Hyg. | pmid:25223942 |
| Amza A et al. | Does mass azithromycin distribution impact child growth and nutrition in Niger? A cluster-randomized trial. | 2014 | PLoS Negl Trop Dis | pmid:25210836 |
| Lourdesamy Anthony AI and Muthukumaru U | Efficacy of azithromycin in the treatment of bronchiectasis. | 2014 | Respirology | pmid:25183304 |
| Caceres SM et al. | Enhanced in vitro formation and antibiotic resistance of nonattached Pseudomonas aeruginosa aggregates through incorporation of neutrophil products. | 2014 | Antimicrob. Agents Chemother. | pmid:25182651 |
| Tsai MS et al. | Jarisch-Herxheimer reaction among HIV-positive patients with early syphilis: azithromycin versus benzathine penicillin G therapy. | 2014 | J Int AIDS Soc | pmid:25174641 |
| Edwards T et al. | Non-participation during azithromycin mass treatment for trachoma in The Gambia: heterogeneity and risk factors. | 2014 | PLoS Negl Trop Dis | pmid:25165994 |
| Pierson RC et al. | A retrospective comparison of antibiotic regimens for preterm premature rupture of membranes. | 2014 | Obstet Gynecol | pmid:25162251 |
| Kemp MW et al. | Maternal intravenous administration of azithromycin results in significant fetal uptake in a sheep model of second trimester pregnancy. | 2014 | Antimicrob. Agents Chemother. | pmid:25155606 |
| Zheng S et al. | Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects. | 2014 | Antimicrob. Agents Chemother. | pmid:25155592 |
| Morita-Ishihara T et al. | Treatment failure with 2 g of azithromycin (extended-release formulation) in gonorrhoea in Japan caused by the international multidrug-resistant ST1407 strain of Neisseria gonorrhoeae. | 2014 | J. Antimicrob. Chemother. | pmid:24777907 |
| Goldstein RC et al. | Fluoroquinolone- and ceftriaxone-based therapy of community-acquired pneumonia in hospitalized patients: the risk of subsequent isolation of multidrug-resistant organisms. | 2014 | Am J Infect Control | pmid:24773792 |
| He S et al. | [Clinical analysis of scrub typhus-associated hemophagocytic syndrome]. | 2014 | Zhonghua Er Ke Za Zhi | pmid:25476431 |
| Pocock JM et al. | Septic arthritis of the hip in a Cambodian child caused by multidrug-resistant Salmonella enterica serovar Typhi with intermediate susceptibility to ciprofloxacin treated with ceftriaxone and azithromycin. | 2014 | Paediatr Int Child Health | pmid:24749773 |
| Uzun S et al. | Azithromycin maintenance treatment in patients with frequent exacerbations of chronic obstructive pulmonary disease (COLUMBUS): a randomised, double-blind, placebo-controlled trial. | 2014 | Lancet Respir Med | pmid:24746000 |
| Wong C and Herath S | Azithromycin for patients with frequent COPD exacerbations. | 2014 | Lancet Respir Med | pmid:24745999 |
| Rodgers S et al. | Challenges in implementing the new BASHH guidelines for the management of gonorrhoea. | 2014 | Int J STD AIDS | pmid:23970641 |
| Kong FY et al. | Azithromycin versus doxycycline for the treatment of genital chlamydia infection: a meta-analysis of randomized controlled trials. | 2014 | Clin. Infect. Dis. | pmid:24729507 |
| Lechtenberg RJ et al. | Variation in adherence to the treatment guidelines for Neisseria gonorrhoeae by clinical practice setting, California, 2009 to 2011. | 2014 | Sex Transm Dis | pmid:24722391 |
| Matheson AI et al. | Prioritizing countries for interventions to reduce child mortality: tools for maximizing the impact of mass drug administration of azithromycin. | 2014 | PLoS ONE | pmid:24837459 |
| Mendu ML and Waikar SS | Drug-drug interactions and acute kidney injury: caveat prescriptor. | 2014 | Am. J. Kidney Dis. | pmid:24820318 |
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| Assani K et al. | IFN-γ stimulates autophagy-mediated clearance of Burkholderia cenocepacia in human cystic fibrosis macrophages. | 2014 | PLoS ONE | pmid:24798083 |
| Chu DJ et al. | Azithromycin enhances the favorable results of paclitaxel and cisplatin in patients with advanced non-small cell lung cancer. | 2014 | Genet. Mol. Res. | pmid:24782093 |
| Mukherjee P et al. | Emergence of high-level azithromycin resistance in Campylobacter jejuni isolates from pediatric diarrhea patients in Kolkata, India. | 2014 | Antimicrob. Agents Chemother. | pmid:24777098 |
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| West SK et al. | Is there evidence for resistance of ocular Chlamydia trachomatis to azithromycin after mass treatment for trachoma control? | 2014 | J. Infect. Dis. | pmid:24446528 |
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| Kaiser C | A coughing spell. | 2014 | JEMS | pmid:24724329 |
| Phillips-Campbell R et al. | Induction of the Chlamydia muridarum stress/persistence response increases azithromycin treatment failure in a murine model of infection. | 2014 | Antimicrob. Agents Chemother. | pmid:24342653 |
| Jang MO et al. | Outcome of intravenous azithromycin therapy in patients with complicated scrub typhus compared with that of doxycycline therapy using propensity-matched analysis. | 2014 | Antimicrob. Agents Chemother. | pmid:24366734 |
| Han MK et al. | Predictors of chronic obstructive pulmonary disease exacerbation reduction in response to daily azithromycin therapy. | 2014 | Am. J. Respir. Crit. Care Med. | pmid:24779680 |
| Khosropour CM et al. | Lack of association between azithromycin and death from cardiovascular causes. | 2014 | N. Engl. J. Med. | pmid:24827057 |