| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Airway Obstruction | D000402 | 13 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Hearing Loss, Sensorineural | D006319 | 8 associated lipids |
| Otitis Media | D010033 | 12 associated lipids |
| Carcinoma, Basal Cell | D002280 | 6 associated lipids |
| Bacterial Infections | D001424 | 21 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Stomach Diseases | D013272 | 7 associated lipids |
| Genital Diseases, Female | D005831 | 7 associated lipids |
| Lung Diseases | D008171 | 37 associated lipids |
| Sarcoidosis | D012507 | 13 associated lipids |
| Hyperglycemia | D006943 | 21 associated lipids |
| Carcinoma, Squamous Cell | D002294 | 14 associated lipids |
| Skin Neoplasms | D012878 | 12 associated lipids |
| Burns | D002056 | 34 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Colitis | D003092 | 69 associated lipids |
Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Graybill JR and Bocanegra R | Treatment alternatives for Mycobacterium kansasii. | 2001 | J. Antimicrob. Chemother. | pmid:11266413 |
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| Butler T et al. | In vitro effects of azithromycin on Salmonella typhi: early inhibition by concentrations less than the MIC and reduction of MIC by alkaline pH and small inocula. | 2001 | J. Antimicrob. Chemother. | pmid:11266420 |
| Kawamura-Sato K et al. | Postantibiotic suppression effect of macrolides on the expression of flagellin in Pseudomonas aeruginosa and Proteus mirabilis. | 2001 | J. Infect. Chemother. | pmid:11406758 |
| St Clair EW et al. | The effects of intravenous doxycycline therapy for rheumatoid arthritis: a randomized, double-blind, placebo-controlled trial. | 2001 | Arthritis Rheum. | pmid:11357896 |
| Kaplan EL et al. | Macrolide therapy of group A streptococcal pharyngitis: 10 days of macrolide therapy (clarithromycin) is more effective in streptococcal eradication than 5 days (azithromycin). | 2001 | Clin. Infect. Dis. | pmid:11360224 |
| Nilius AM et al. | Comparative in vitro activity of ABT-773, a novel antibacterial ketolide. | 2001 | Antimicrob. Agents Chemother. | pmid:11408246 |
| Vallejo C et al. | Resolution of cyclosporine-induced gingival hyperplasia resistant to azithromycin by switching to tacrolimus. | 2001 | Haematologica | pmid:11146586 |
| Schlegel L et al. | In vitro activity of midecamycin diacetate, a 16-membered macrolide, against Streptococcus pyogenes isolated in France, 1995-1999. | 2001 | Clin. Microbiol. Infect. | pmid:11531981 |
| Kain KC et al. | Malaria chemoprophylaxis in the age of drug resistance. I. Currently recommended drug regimens. | 2001 | Clin. Infect. Dis. | pmid:11418883 |
| Tabbara KF | Trachoma: a review. | 2001 | J Chemother | pmid:11434524 |
| Lisby G et al. | Bacteremia and meningitis caused by a macrolide-sensitive strain of Streptococcus pneumoniae during treatment with azithromycin. | 2001 | Clin. Infect. Dis. | pmid:11438918 |
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| Gieffers J et al. | Chlamydia pneumoniae infection in circulating human monocytes is refractory to antibiotic treatment. | 2001 | Circulation | pmid:11157684 |
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| Simsir A et al. | Rhodococcus equi and cytomegalovirus pneumonia in a renal transplant patient: diagnosis by fine-needle aspiration biopsy. | 2001 | Diagn. Cytopathol. | pmid:11169894 |
| Nagai K et al. | Activities of a new fluoroketolide, HMR 3787, and its (des)-fluor derivative RU 64399 compared to those of telithromycin, erythromycin A, azithromycin, clarithromycin, and clindamycin against macrolide-susceptible or -resistant Streptococcus pneumoniae and S. pyogenes. | 2001 | Antimicrob. Agents Chemother. | pmid:11600391 |
| Cascaval RI and Lancaster DJ | Hypersensitivity syndrome associated with azithromycin. | 2001 | Am. J. Med. | pmid:11247598 |
| Amábile-Cuevas CF et al. | Comparative in vitro activity of moxifloxacin by E-test against Streptococcus pyogenes. | 2001 | Clin. Infect. Dis. | pmid:11249826 |
| De Diego JI et al. | Comparison of amoxicillin and azithromycin in the prevention of recurrent acute otitis media. | 2001 | Int. J. Pediatr. Otorhinolaryngol. | pmid:11249979 |
| Intrauterine devices: antibiotic prophylaxis not necessary during insertion. | 2001 | Prescrire Int | pmid:11718174 | |
| Golledge CL and Riley TV | The efficacy of an antibiotic protocol for community-acquired pneumonia. | 2001 | Med. J. Aust. | pmid:11700844 |
| Toro C et al. | [Prevalence of primary Helicobacter pylori resistance to eight antimicrobial agents in a hospital in Madrid]. | 2001 | Rev Esp Quimioter | pmid:11704771 |
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| Samarendra P et al. | QT prolongation associated with azithromycin/amiodarone combination. | 2001 | Pacing Clin Electrophysiol | pmid:11707055 |
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| Treadway G and Reisman A | Tolerability of 3-day, once-daily azithromycin suspension versus standard treatments for community-acquired paediatric infectious diseases. | 2001 | Int. J. Antimicrob. Agents | pmid:11711256 |
| Page RL et al. | Possible interaction between intravenous azithromycin and oral cyclosporine. | 2001 | Pharmacotherapy | pmid:11714218 |
| Amsden GW | Advanced-generation macrolides: tissue-directed antibiotics. | 2001 | Int. J. Antimicrob. Agents | pmid:11574189 |
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| Butler T | Effect of increased inoculum of Salmonella typhi on MIC of azithromycin and resultant growth characteristics. | 2001 | J. Antimicrob. Chemother. | pmid:11733476 |
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| Kaiser L et al. | Role of nasopharyngeal culture in antibiotic prescription for patients with common cold or acute sinusitis. | 2001 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:11561799 |
| Gray GC et al. | Randomized, placebo-controlled clinical trial of oral azithromycin prophylaxis against respiratory infections in a high-risk, young adult population. | 2001 | Clin. Infect. Dis. | pmid:11528569 |
| Urbano F and Urbano P | Azithromycin in healthy adults? | 2001 | Clin. Microbiol. Infect. | pmid:11531993 |
| Miyazaki S et al. | Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice. | 2001 | J. Antimicrob. Chemother. | pmid:11533011 |
| Milkovic-Kraus S and Kanceljak-Macan B | Occupational airborne allergic contact dermatitis from azithromycin. | 2001 | Contact Derm. | pmid:11553158 |
| Gray GC and Ryan MA | Azithromycin chemoprophylaxis. | 2001 | J. Infect. Dis. | pmid:11494171 |
| Arellano-Rodrigo E et al. | [Torsade de pointes and cardiorespiratory arrest induced by azithromycin in a patient with congenital long QT syndrome]. | 2001 | Med Clin (Barc) | pmid:11459586 |
| Dillon JA et al. | Antimicrobial susceptibility of Neisseria gonorrhoeae isolates from three Caribbean countries: Trinidad, Guyana, and St. Vincent. | 2001 | Sex Transm Dis | pmid:11518867 |
| Dillon JA et al. | Reduced susceptibility to azithromycin and high percentages of penicillin and tetracycline resistance in Neisseria gonorrhoeae isolates from Manaus, Brazil, 1998. | 2001 | Sex Transm Dis | pmid:11518869 |
| Skerk V et al. | Azithromycin and doxycycline in the treatment of female patients with acute urethral syndrome caused by Ureaplasma urealyticum: significance of duration of clinical symptoms. | 2001 | Drugs Exp Clin Res | pmid:11822223 |
| [Antibiotics in respiratory tract infections. Enormous differences in compliance]. | 2001 | MMW Fortschr Med | pmid:11824169 | |
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| Samra Z et al. | In vitro susceptibility of recent clinical isolates of Chlamydia trachomatis to macrolides and tetracyclines. | 2001 | Diagn. Microbiol. Infect. Dis. | pmid:11337185 |
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| Kacmar J et al. | A randomized trial of azithromycin versus amoxicillin for the treatment of Chlamydia trachomatis in pregnancy. | 2001 | Infect Dis Obstet Gynecol | pmid:11916175 |
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| Bragina EY et al. | Electron microscopic evidence of persistent chlamydial infection following treatment. | 2001 | J Eur Acad Dermatol Venereol | pmid:11763379 |
| Swanston WH et al. | Single dose (direct observed) azithromycin therapy for Neisseria gonorrhoeae and Chlamydia trachomatis in STD clinic attenders with genital discharge in Trinidad and Tobago. | 2001 | West Indian Med J | pmid:11769023 |
| Mendes CM et al. | In vitro susceptibility of gram-positive cocci isolated from skin and respiratory tract to azithromycin and twelve other antimicrobial agents. | 2001 | Braz J Infect Dis | pmid:11779453 |
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| Safak MA et al. | A comparative study of azithromycin and pseudoephedrine hydrochloride for otitis media with effusion in children. | 2001 | Acta Otolaryngol. | pmid:11813896 |
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| Treadway G | Azithromycin: a new 15-membered macrolide. | 2001 | Jpn J Antibiot | pmid:11296412 |
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| Griffith DE et al. | Azithromycin-containing regimens for treatment of Mycobacterium avium complex lung disease. | 2001 | Clin. Infect. Dis. | pmid:11340525 |
| Tan JS et al. | Persistently positive culture results in a patient with community-acquired pneumonia due to Legionella pneumophila. | 2001 | Clin. Infect. Dis. | pmid:11340527 |
| Westfall DS et al. | Inoculation of two genotypes of Hemobartonella felis (California and Ohio variants) to induce infection in cats and the response to treatment with azithromycin. | 2001 | Am. J. Vet. Res. | pmid:11341386 |
| Bowden FJ et al. | Azithromycin and pelvic inflammatory disease in the Northern Territory. | 2001 | Med. J. Aust. | pmid:11346115 |
| Jacobson JM et al. | Dose-escalation, phase I/II study of azithromycin and pyrimethamine for the treatment of toxoplasmic encephalitis in AIDS. | 2001 | AIDS | pmid:11316995 |
| Kays MB and Denys GA | In vitro activity and pharmacodynamics of azithromycin and clarithromycin against Streptococcus pneumoniae based on serum and intrapulmonary pharmacokinetics. | 2001 | Clin Ther | pmid:11318076 |
| Dinos GP et al. | Insights into the mechanism of azithromycin interaction with an Escherichia coli functional ribosomal complex. | 2001 | Mol. Pharmacol. | pmid:11353804 |
| Gupta S et al. | Pharmacokinetic and safety profile of desloratadine and fexofenadine when coadministered with azithromycin: a randomized, placebo-controlled, parallel-group study. | 2001 | Clin Ther | pmid:11318079 |
| Parsad D et al. | Azithromycin monthly pulse vs daily doxycycline in the treatment of acne vulgaris. | 2001 | J. Dermatol. | pmid:11280457 |
| Waring AL et al. | Development of a genomics-based PCR assay for detection of Mycoplasma pneumoniae in a large outbreak in New York State. | 2001 | J. Clin. Microbiol. | pmid:11283060 |
| Lechner A and Bruckner DA | Oligella ureolytica in blood culture: contaminant or infection? | 2001 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:11305472 |
| Dreses-Werringloer U et al. | Effects of azithromycin and rifampin on Chlamydia trachomatis infection in vitro. | 2001 | Antimicrob. Agents Chemother. | pmid:11600348 |
| Littler WA | Clindamycin suspension and endocarditis prophylaxis. | 2001 | Br Dent J | pmid:11352383 |
| Ikegaya S et al. | [Effect of azithromycin on cytokine production by THP-1 cells]. | 2001 | Jpn J Antibiot | pmid:12575425 |
| Tateda K et al. | Azithromycin inhibits quorum sensing in Pseudomonas aeruginosa. | 2001 | Antimicrob. Agents Chemother. | pmid:11353657 |
| Kato T et al. | [Effect of azithromycin on cytokine production in human bronchial epithelial cell line, BEAS-2B]. | 2001 | Jpn J Antibiot | pmid:12575426 |
| Pechère JC | Azithromycin reduces the production of virulence factors in Pseudomonas aeruginosa by inhibiting quorum sensing. | 2001 | Jpn J Antibiot | pmid:12575427 |
| Tateda K et al. | [MIC, sub-MIC of macrolide resistant bacteria--special reference to their quorum-sensing system]. | 2001 | Jpn J Antibiot | pmid:12575433 |
| Grand A et al. | [Subacute infectious endocarditis due to the agent of cat scratch fever: Bartonella henselae]. | 2001 | Arch Mal Coeur Vaiss | pmid:11265556 |