Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Airway Obstruction D000402 13 associated lipids
Stomach Ulcer D013276 75 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Otitis Media D010033 12 associated lipids
Carcinoma, Basal Cell D002280 6 associated lipids
Bacterial Infections D001424 21 associated lipids
Pain D010146 64 associated lipids
Stomach Diseases D013272 7 associated lipids
Genital Diseases, Female D005831 7 associated lipids
Lung Diseases D008171 37 associated lipids
Sarcoidosis D012507 13 associated lipids
Hyperglycemia D006943 21 associated lipids
Carcinoma, Squamous Cell D002294 14 associated lipids
Skin Neoplasms D012878 12 associated lipids
Burns D002056 34 associated lipids
Inflammation D007249 119 associated lipids
Colitis D003092 69 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


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Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Azithromycin treatment failures in syphilis infections--San Francisco, California, 2002-2003. 2004 MMWR Morb. Mortal. Wkly. Rep. pmid:15017376
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Pieh C et al. [Cotton wool spots in a 16-year-old girl]. 2005 Ophthalmologe pmid:15095109
Riedner G et al. Single-dose azithromycin versus penicillin G benzathine for the treatment of early syphilis. 2005 N. Engl. J. Med. pmid:16177249
Holmes KK Azithromycin versus penicillin G benzathine for early syphilis. 2005 N. Engl. J. Med. pmid:16177256
Tripathi R et al. Blood schizontocidal activity of azithromycin and its combination with alpha/beta arteether against multi-drug resistant Plasmodium yoelii nigeriensis, a novel MDR parasite model for antimalarial screening. 2005 Parasitology pmid:16178350
Azithromycin extended-release (Zmax) for sinusitis and pneumonia. 2005 Med Lett Drugs Ther pmid:16186790
Chaudhary C et al. A pilot study on antimicrobial susceptibility of Neisseria gonorrhoeae isolates from Nepal. 2005 Sex Transm Dis pmid:16205307
West ES et al. Surgery for Trichiasis, Antibiotics to prevent Recurrence (STAR) Clinical Trial methodology. 2005 Ophthalmic Epidemiol pmid:16033749
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Alexander ND et al. An index of community ocular Chlamydia trachomatis load for control of trachoma. 2005 Trans. R. Soc. Trop. Med. Hyg. pmid:15653119
Cárceles CM et al. Pharmacokinetics of azithromycin after i.v. and i.m. administration to sheep. 2005 J. Vet. Pharmacol. Ther. pmid:16207311
Barker PM et al. Effect of macrolides on in vivo ion transport across cystic fibrosis nasal epithelium. 2005 Am. J. Respir. Crit. Care Med. pmid:15657462
D'Ignazio J et al. Novel, single-dose microsphere formulation of azithromycin versus 7-day levofloxacin therapy for treatment of mild to moderate community-acquired Pneumonia in adults. 2005 Antimicrob. Agents Chemother. pmid:16189077
Schalock PC and Dinulos JG Mycoplasma pneumoniae-induced Stevens-Johnson syndrome without skin lesions: fact or fiction? 2005 J. Am. Acad. Dermatol. pmid:15692479
No value in antibiotic therapy for HD. 2005 Health News pmid:16189853
Preheim LC et al. Effect of cirrhosis on antibiotic efficacy in a rat model of pneumococcal pneumonia. 2005 Diagn. Microbiol. Infect. Dis. pmid:15698715
Valdes A and Johnson JR Septic pleuritis and abdominal abscess formation caused by Rhodococcus equi in a foal. 2005 J. Am. Vet. Med. Assoc. pmid:16190597
Arguedas A et al. A randomized, multicenter, double blind, double dummy trial of single dose azithromycin versus high dose amoxicillin for treatment of uncomplicated acute otitis media. 2005 Pediatr. Infect. Dis. J. pmid:15702045
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Cárceles CM et al. Pharmacokinetics of azithromycin after intravenous and intramuscular administration to goats. 2005 J. Vet. Pharmacol. Ther. pmid:15720515
Jacobs RF et al. Pharmacokinetics of intravenously administered azithromycin in pediatric patients. 2005 Pediatr. Infect. Dis. J. pmid:15665708
Verma A and Dhawan A Re: Trial of metronidazole vs. azithromycin for treatment of cyclosporine-induced gingival overgrowth. 2005 Pediatr Transplant pmid:15667627
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Bahrami G et al. High performance liquid chromatographic determination of azithromycin in serum using fluorescence detection and its application in human pharmacokinetic studies. 2005 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:15876560
Zou CC and Liang L Multiple hypoechoic lesions in spleen and Mycoplasma pneumoniae infection. 2005 Indian Pediatr pmid:15876602
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Cazzola M et al. Treatment of acute exacerbation of severe-to-very severe COPD with azithromycin in patients vaccinated against Streptococcus pneumoniae. 2005 Respir Med pmid:15878482
Sommer A Systemic antibiotics for communitywide trachoma control. 2005 Arch. Ophthalmol. pmid:15883291
Babic Z et al. Increased activity of Pgp multidrug transporter in patients with Helicobacter pylori infection. 2005 World J. Gastroenterol. pmid:15884110
Grayston JT et al. Azithromycin for the secondary prevention of coronary events. 2005 N. Engl. J. Med. pmid:15843666
Anderson JL Infection, antibiotics, and atherothrombosis--end of the road or new beginnings? 2005 N. Engl. J. Med. pmid:15843674
Blessing E et al. A 6 week course of azithromycin treatment has no beneficial effect on atherosclerotic lesion development in apolipoprotein E-deficient mice chronically infected with Chlamydia pneumoniae. 2005 J. Antimicrob. Chemother. pmid:15845780
Ritchlin CT Treatment of reactive arthritis with azithromycin. 2005 Curr Rheumatol Rep pmid:15918991
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Spooner K et al. Azithromcyin might not protect against Treponema pallidum infection or reactivation in HIV type 1-infected patients. 2005 Clin. Infect. Dis. pmid:16007551
Koch DE et al. Azithromycin extraction from municipal wastewater and quantitation using liquid chromatography/mass spectrometry. 2005 J Chromatogr A pmid:15941034
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Srinivasan R and Yeo TH Are newer macrolides effective in eradicating carriage of pertussis? 2005 Arch. Dis. Child. pmid:15723933
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Berquand A et al. Interaction of the macrolide antibiotic azithromycin with lipid bilayers: effect on membrane organization, fluidity, and permeability. 2005 Pharm. Res. pmid:15835753
Dunne MW et al. A multicenter study of azithromycin, alone and in combination with chloroquine, for the treatment of acute uncomplicated Plasmodium falciparum malaria in India. 2005 J. Infect. Dis. pmid:15838784
Vainas T et al. Secondary prevention of atherosclerosis through chlamydia pneumoniae eradication (SPACE Trial): a randomised clinical trial in patients with peripheral arterial disease. 2005 Eur J Vasc Endovasc Surg pmid:15749042
Hansen CR et al. Long-term azitromycin treatment of cystic fibrosis patients with chronic Pseudomonas aeruginosa infection; an observational cohort study. 2005 J. Cyst. Fibros. pmid:15752679
Janahi IA et al. Rapidly progressive lung disease in a patient with cystic fibrosis on long-term azithromycin: possible role of mycoplasma infection. 2005 J. Cyst. Fibros. pmid:15752685
García Vázquez E et al. Lower mortality among patients with community-acquired pneumonia treated with a macrolide plus a beta-lactam agent versus a beta-lactam agent alone. 2005 Eur. J. Clin. Microbiol. Infect. Dis. pmid:15782278
Holas C et al. A pooled analysis of seven randomized crossover studies of the palatability of cefdinir oral suspension versus amoxicillin/clavulanate potassium, cefprozil, azithromycin, and amoxicillin in children aged 4 to 8 years. 2005 Clin Ther pmid:16507381
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Halpern MT et al. Meta-analysis of bacterial resistance to macrolides. 2005 J. Antimicrob. Chemother. pmid:15772147
Kuzman I et al. Clinical efficacy and safety of a short regimen of azithromycin sequential therapy vs standard cefuroxime sequential therapy in the treatment of community-acquired pneumonia: an international, randomized, open-label study. 2005 J Chemother pmid:16433194
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Drago L et al. Kinetic bactericidal activity of telithromycin, azithromycin and clarithromycin against respiratory pathogens. 2005 APMIS pmid:16309423
Baciewicz AM et al. Azithromycin-induced hepatoxicity. 2005 Am. J. Med. pmid:16378809
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Amsden GW Anti-inflammatory effects of macrolides--an underappreciated benefit in the treatment of community-acquired respiratory tract infections and chronic inflammatory pulmonary conditions? 2005 J. Antimicrob. Chemother. pmid:15590715
Kim MH et al. Polymorphic ventricular tachycardia with a normal QT interval following azithromycin. 2005 Pacing Clin Electrophysiol pmid:16359290
Dereli T et al. Azithromycin in the treatment of papulopustular rosacea. 2005 J. Dermatol. pmid:16361757