| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Airway Obstruction | D000402 | 13 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Hearing Loss, Sensorineural | D006319 | 8 associated lipids |
| Otitis Media | D010033 | 12 associated lipids |
| Carcinoma, Basal Cell | D002280 | 6 associated lipids |
| Bacterial Infections | D001424 | 21 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Stomach Diseases | D013272 | 7 associated lipids |
| Genital Diseases, Female | D005831 | 7 associated lipids |
| Lung Diseases | D008171 | 37 associated lipids |
| Sarcoidosis | D012507 | 13 associated lipids |
| Hyperglycemia | D006943 | 21 associated lipids |
| Carcinoma, Squamous Cell | D002294 | 14 associated lipids |
| Skin Neoplasms | D012878 | 12 associated lipids |
| Burns | D002056 | 34 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Colitis | D003092 | 69 associated lipids |
Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Cole MJ et al. | Risk factors for antimicrobial-resistant Neisseria gonorrhoeae in Europe. | 2014 | Sex Transm Dis | pmid:25581808 |
| Zhou P et al. | Occurrence of congenital syphilis after maternal treatment with azithromycin during pregnancy. | 2007 | Sex Transm Dis | pmid:17589329 |
| Yasin RM et al. | Comparison of E-test with agar dilution methods in testing susceptibility of N. gonorrhoeae to azithromycin. | 1997 | Sex Transm Dis | pmid:9153733 |
| Steen R et al. | Evidence of declining STD prevalence in a South African mining community following a core-group intervention. | 2000 | Sex Transm Dis | pmid:10654860 |
| Jordan SJ and Geisler WM | Azithromycin for rectal chlamydia: is it time to leave azithromycin on the shelf?...Not yet. | 2014 | Sex Transm Dis | pmid:24413485 |
| Nieuwenhuis RF et al. | Unusual presentation of early lymphogranuloma venereum in an HIV-1 infected patient: effective treatment with 1 g azithromycin. | 2003 | Sex Transm Infect | pmid:14663119 |
| Bignell C and Garley J | Azithromycin in the treatment of infection with Neisseria gonorrhoeae. | 2010 | Sex Transm Infect | pmid:20940153 |
| Downing J et al. | Management of cases testing positive for gonococcal infection in a community-based chlamydia screening programme. | 2010 | Sex Transm Infect | pmid:20940161 |
| Falk L et al. | Tetracycline treatment does not eradicate Mycoplasma genitalium. | 2003 | Sex Transm Infect | pmid:12902584 |
| Björnelius E et al. | macrolide resistance in Stockholm, Sweden. | 2017 | Sex Transm Infect | pmid:27502694 |
| Horner PJ | Azithromycin antimicrobial resistance and genital Chlamydia trachomatis infection: duration of therapy may be the key to improving efficacy. | 2012 | Sex Transm Infect | pmid:22416272 |
| Bartelsman M et al. | Comparison of two Gram stain point-of-care systems for urogenital gonorrhoea among high-risk patients: diagnostic accuracy and cost-effectiveness before and after changing the screening algorithm at an STI clinic in Amsterdam. | 2014 | Sex Transm Infect | pmid:24860102 |
| Murray S and Marshall L | Empiric NSU treatment needs updating. | 2014 | Sex Transm Infect | pmid:25028712 |
| Jang D et al. | Correlation between culture testing of swabs and ligase chain reaction of first void urine from patients recently treated for Chlamydia trachomatis. | 2003 | Sex Transm Infect | pmid:12794211 |
| Gayet-Ageron A et al. | Assessment of a real-time PCR test to diagnose syphilis from diverse biological samples. | 2009 | Sex Transm Infect | pmid:19155240 |
| Ito S et al. | Selection of Mycoplasma genitalium strains harbouring macrolide resistance-associated 23S rRNA mutations by treatment with a single 1 g dose of azithromycin. | 2011 | Sex Transm Infect | pmid:21653933 |
| Fifer H et al. | Gonorrhoea treatment position statement. | 2015 | Sex Transm Infect | pmid:26195472 |
| Björnelius E et al. | Antibiotic treatment of symptomatic Mycoplasma genitalium infection in Scandinavia: a controlled clinical trial. | 2008 | Sex Transm Infect | pmid:17932127 |
| Horner P | The case for further treatment studies of uncomplicated genital Chlamydia trachomatis infection. | 2006 | Sex Transm Infect | pmid:16877590 |
| Rice LB | Will use of combination cephalosporin/azithromycin therapy forestall resistance to cephalosporins in Neisseria gonorrhoeae? | 2015 | Sex Transm Infect | pmid:25926405 |