Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Airway Obstruction D000402 13 associated lipids
Stomach Ulcer D013276 75 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Otitis Media D010033 12 associated lipids
Carcinoma, Basal Cell D002280 6 associated lipids
Bacterial Infections D001424 21 associated lipids
Pain D010146 64 associated lipids
Stomach Diseases D013272 7 associated lipids
Genital Diseases, Female D005831 7 associated lipids
Lung Diseases D008171 37 associated lipids
Sarcoidosis D012507 13 associated lipids
Hyperglycemia D006943 21 associated lipids
Carcinoma, Squamous Cell D002294 14 associated lipids
Skin Neoplasms D012878 12 associated lipids
Burns D002056 34 associated lipids
Inflammation D007249 119 associated lipids
Colitis D003092 69 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Kuzman I et al. Azithromycin for treatment of community acquired pneumonia caused by Legionella pneumophila: a retrospective study. 1995 Scand. J. Infect. Dis. pmid:8588143
Carbon C [Azithromycin: from macrolides to azalides]. 1995 Pathol. Biol. pmid:8539067
[Special issue devoted to azithromycin]. 1995 Pathol. Biol. pmid:8539068
Bergogne-Bérézin E [Azithromycin: tissue pharmacology]. 1995 Pathol. Biol. pmid:8539071
Singlas E [Clinical pharmacokinetics of azithromycin]. 1995 Pathol. Biol. pmid:8539072
Schlossberg D Azithromycin and clarithromycin. 1995 Med. Clin. North Am. pmid:7791424
Weber JT and Johnson RE New treatments for Chlamydia trachomatis genital infection. 1995 Clin. Infect. Dis. pmid:7795110
Nilsen OG Pharmacokinetics of macrolides. Comparison of plasma, tissue and free concentrations with special reference to roxithromycin. 1995 Infection pmid:7782117
Backman JT et al. Azithromycin does not increase plasma concentrations of oral midazolam. 1995 Int J Clin Pharmacol Ther pmid:7582388
Harris S et al. Azithromycin and terfenadine: lack of drug interaction. 1995 Clin. Pharmacol. Ther. pmid:7554704
Bokemeyer B [Combined therapy with azithromycin and omeprazole for the eradication of Helicobacter pylori]. 1995 Dtsch. Med. Wochenschr. pmid:7555645
Rizzato G et al. Efficacy of a three day course of azithromycin in moderately severe community-acquired pneumonia. 1995 Eur. Respir. J. pmid:7789484
Sher AA et al. [Interactions in the system of copper ion-azalide (azithromycin)]. 1994 Sep-Oct Antibiot. Khimioter. pmid:7695446
Handsfield HH et al. Multicenter trial of single-dose azithromycin vs. ceftriaxone in the treatment of uncomplicated gonorrhea. Azithromycin Gonorrhea Study Group. 1994 Mar-Apr Sex Transm Dis pmid:9071422
Tyndall MW et al. Single dose azithromycin for the treatment of chancroid: a randomized comparison with erythromycin. 1994 Jul-Aug Sex Transm Dis pmid:7974076
Lang R et al. Therapeutic effects of roxithromycin and azithromycin in experimental murine brucellosis. 1994 Jul-Aug Chemotherapy pmid:8082413
Steingrímsson O et al. Single dose azithromycin treatment of gonorrhea and infections caused by C. trachomatis and U. urealyticum in men. 1994 Jan-Feb Sex Transm Dis pmid:8140488
Pacor ML et al. [Safety of azithromycin in patients allergic to penicillin and cephalosporin]. 1994 Clin Ter pmid:8001336
Carlier MB et al. Accumulation, release and subcellular localization of azithromycin in phagocytic and non-phagocytic cells in culture. 1994 Int J Tissue React pmid:7558665
Kelsey JJ et al. Presence of azithromycin breast milk concentrations: a case report. 1994 Am. J. Obstet. Gynecol. pmid:8178871