| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Airway Obstruction | D000402 | 13 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Hearing Loss, Sensorineural | D006319 | 8 associated lipids |
| Otitis Media | D010033 | 12 associated lipids |
| Carcinoma, Basal Cell | D002280 | 6 associated lipids |
| Bacterial Infections | D001424 | 21 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Stomach Diseases | D013272 | 7 associated lipids |
| Genital Diseases, Female | D005831 | 7 associated lipids |
| Lung Diseases | D008171 | 37 associated lipids |
| Sarcoidosis | D012507 | 13 associated lipids |
| Hyperglycemia | D006943 | 21 associated lipids |
| Carcinoma, Squamous Cell | D002294 | 14 associated lipids |
| Skin Neoplasms | D012878 | 12 associated lipids |
| Burns | D002056 | 34 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Colitis | D003092 | 69 associated lipids |
Azithramycine
Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.
Cross Reference
Introduction
To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Azithramycine?
Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (156)
- Clin. Infect. Dis. (64)
- J. Antimicrob. Chemother. (50)
- Others (435)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Azithramycine
PubChem Associated disorders and diseases
What pathways are associated with Azithramycine
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Azithramycine?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (66)
- J. Antimicrob. Chemother. (25)
- Clin. Infect. Dis. (13)
- Others (151)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Azithramycine?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Azithramycine?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Azithramycine?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (44)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (10)
- Others (126)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Azithramycine?
Mouse Model
Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).
Knock-out
Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).
Tissue Model
Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Azithramycine
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Skerk V et al. | Azithromycin and doxycycline in the treatment of female patients with acute urethral syndrome caused by Ureaplasma urealyticum: significance of duration of clinical symptoms. | 2001 | Drugs Exp Clin Res | pmid:11822223 |
| [Antibiotics in respiratory tract infections. Enormous differences in compliance]. | 2001 | MMW Fortschr Med | pmid:11824169 | |
| [Chronic bronchitis. When to use antibiotics?]. | 2001 | MMW Fortschr Med | pmid:11824170 | |
| Burton MJ et al. | Azithromycin for the treatment and control of trachoma. | 2002 | Expert Opin Pharmacother | pmid:11829725 |
| Biswas S | In-vitro antimalarial activity of azithromycin against chloroquine sensitive and chloroquine resistant Plasmodium falciparum. | 2001 Oct-Dec | J Postgrad Med | pmid:11832638 |
| Gaylor AS and Reilly JC | Therapy with macrolides in patients with cystic fibrosis. | 2002 | Pharmacotherapy | pmid:11837560 |
| Smith SR et al. | A double-blind placebo-controlled trial of azithromycin as an adjunct to non-surgical treatment of periodontitis in adults: clinical results. | 2002 | J. Clin. Periodontol. | pmid:11846850 |
| Calvo A et al. | [Activity of different antimicrobial agents against penicillin-resistant Streptococcus pneumoniae]. | 2001 | Rev Esp Quimioter | pmid:11856980 |
| Wu ML et al. | Enterocolonic Mycobacterium avium-intracellulare. | 2002 | Arch. Pathol. Lab. Med. | pmid:11860323 |
| Duff P | Antibiotic selection in obstetrics: making cost-effective choices. | 2002 | Clin Obstet Gynecol | pmid:11862059 |
| Wolter J et al. | Effect of long term treatment with azithromycin on disease parameters in cystic fibrosis: a randomised trial. | 2002 | Thorax | pmid:11867823 |
| Zhou F et al. | High accuracy mass measurement of peptides with internal calibration using a dual electrospray ionization sprayer system for protein identification. | 2002 | Rapid Commun. Mass Spectrom. | pmid:11870887 |
| Martinez SM et al. | Azithromycin prophylaxis during a hospitalwide outbreak of a pertussis-like illness. | 2001 | Infect Control Hosp Epidemiol | pmid:11876458 |
| Muirhead GJ et al. | The effects of steady-state erythromycin and azithromycin on the pharmacokinetics of sildenafil in healthy volunteers. | 2002 | Br J Clin Pharmacol | pmid:11879258 |
| Parchure N et al. | Effect of azithromycin treatment on endothelial function in patients with coronary artery disease and evidence of Chlamydia pneumoniae infection. | 2002 | Circulation | pmid:11901039 |
| SoRelle R | Treatment with azithromycin improves endothelial function. | 2002 | Circulation | pmid:11902195 |
| Ohara T et al. | [Protective effect of azithromycin against verotoxin]. | 2002 | Kansenshogaku Zasshi | pmid:11905000 |
| Salaria M and Singh M | Atypical pneumonia in children. | 2002 | Indian Pediatr | pmid:11910135 |
| Desta Z et al. | In vitro inhibition of pimozide N-dealkylation by selective serotonin reuptake inhibitors and azithromycin. | 2002 | J Clin Psychopharmacol | pmid:11910261 |
| Kacmar J et al. | A randomized trial of azithromycin versus amoxicillin for the treatment of Chlamydia trachomatis in pregnancy. | 2001 | Infect Dis Obstet Gynecol | pmid:11916175 |
| Treadway G et al. | The safety of azithromycin in the treatment of adults with community-acquired respiratory tract infections. | 2002 | Int. J. Antimicrob. Agents | pmid:11932140 |
| Nalbanski B and Nalbanski A | [Treatment of Chlamydia trachomatis with azatril]. | 2002 | Akush Ginekol (Sofiia) | pmid:11935692 |
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| Amsden GW et al. | A study of the interaction potential of azithromycin and clarithromycin with atorvastatin in healthy volunteers. | 2002 | J Clin Pharmacol | pmid:11936570 |
| Lacroix JS et al. | Symptoms and clinical and radiological signs predicting the presence of pathogenic bacteria in acute rhinosinusitis. | 2002 | Acta Otolaryngol. | pmid:11936912 |
| King A et al. | Erythromycin susceptibility of viridans streptococci from the normal throat flora of patients treated with azithromycin or clarithromycin. | 2002 | Clin. Microbiol. Infect. | pmid:11952721 |
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| Ekici A et al. | Effect of azithromycin on the severity of bronchial hyperresponsiveness in patients with mild asthma. | 2002 | J Asthma | pmid:11990233 |
| Mohler AM | Treatment of streptococcal pharyngitis. | 2002 | Am Fam Physician | pmid:11996411 |
| Davis JL et al. | Pharmacokinetics of azithromycin in foals after i.v. and oral dose and disposition into phagocytes. | 2002 | J. Vet. Pharmacol. Ther. | pmid:12000529 |
| Champney WS and Miller M | Inhibition of 50S ribosomal subunit assembly in Haemophilus influenzae cells by azithromycin and erythromycin. | 2002 | Curr. Microbiol. | pmid:12000992 |
| Mandell GL and Coleman EJ | Effect of antipyretic agents on uptake, transport, and release of antimicrobial agents by human polymorphonuclear leukocytes. | 2002 | J. Infect. Dis. | pmid:12001049 |
| Kutlin A et al. | Effect of gemifloxacin on viability of Chlamydia pneumoniae (Chlamydophila pneumoniae) in an in vitro continuous infection model. | 2002 | J. Antimicrob. Chemother. | pmid:12003969 |
| Jung R et al. | Intracellular activity of ABT-773 and other antimicrobial agents against Legionella pneumophila. | 2002 | J. Antimicrob. Chemother. | pmid:12003984 |
| Rustomjee R et al. | A randomized controlled trial of azithromycin versus doxycycline/ciprofloxacin for the syndromic management of sexually transmitted infections in a resource-poor setting. | 2002 | J. Antimicrob. Chemother. | pmid:12003988 |
| Voytilla KL et al. | Visual compatibility of azithromycin with 24 commonly used drugs during simulated Y-site delivery. | 2002 | Am J Health Syst Pharm | pmid:12004465 |
| [Unfortunately without effectiveness: chlamydia eradication after infarct]. | 2002 | MMW Fortschr Med | pmid:12014269 | |
| Suriawinata A and Min AD | A 33-year-old woman with jaundice after azithromycin use. | 2002 | Semin. Liver Dis. | pmid:12016551 |
| Valleala H et al. | [The unknown SAPHO]. | 2000 | Duodecim | pmid:12017613 |
| Evans AT et al. | Azithromycin for acute bronchitis: a randomised, double-blind, controlled trial. | 2002 | Lancet | pmid:12020525 |
| Campos-Outcalt D et al. | Use of directly observed azithromycin treatment for syphilis in a homeless woman. | 2002 | Sex Transm Dis | pmid:12035029 |
| Ortega E et al. | In vitro and ex vivo effects of erythromycin A, azithromycin and josamycin on the splenic response to specific antigens and mitogens. | 2002 | J. Antimicrob. Chemother. | pmid:12039899 |
| Chokephaibulkit K et al. | Intestinal parasitic infections among human immunodeficiency virus-infected and -uninfected children hospitalized with diarrhea in Bangkok, Thailand. | 2001 | Southeast Asian J. Trop. Med. Public Health | pmid:12041552 |
| Lisby JG et al. | [Bacteremia and meningitis caused by Streptococcus pneumoniae during treatment with azithromycin]. | 2002 | Ugeskr. Laeg. | pmid:12043408 |
| Nishikawa T | [Comment on the contribution by Weigl CB et al. "Papillomatosis confluens et reticularis"]. | 2002 | Hautarzt | pmid:12063751 |
| Batieha A et al. | No advantage of treating acute respiratory tract infections with azithromycin in a placebo-controlled study. | 2002 | Scand. J. Infect. Dis. | pmid:12064684 |
| Carryn S et al. | Comparative intracellular (THP-1 macrophage) and extracellular activities of beta-lactams, azithromycin, gentamicin, and fluoroquinolones against Listeria monocytogenes at clinically relevant concentrations. | 2002 | Antimicrob. Agents Chemother. | pmid:12069960 |
| Babl FE et al. | Experimental acute otitis media due to nontypeable Haemophilus influenzae: comparison of high and low azithromycin doses with placebo. | 2002 | Antimicrob. Agents Chemother. | pmid:12069974 |
| Chimura T | [Changes of antibody titers during antimicrobial therapy including levofloxacin for Chlamydia infections in the obstetrics and gynecology field]. | 2002 | Jpn J Antibiot | pmid:12071097 |
| Cohen R et al. | Comparison of two dosages of azithromycin for three days versus penicillin V for ten days in acute group A streptococcal tonsillopharyngitis. | 2002 | Pediatr. Infect. Dis. J. | pmid:12075760 |
| Schaad UB et al. | Azithromycin versus penicillin V for treatment of acute group A streptococcal pharyngitis. | 2002 | Pediatr. Infect. Dis. J. | pmid:12075761 |
| Domeika M et al. | Chlamydia trachomatis infections in eastern Europe: legal aspects, epidemiology, diagnosis, and treatment. | 2002 | Sex Transm Infect | pmid:12081171 |
| Patrick DM et al. | Heterosexual outbreak of infectious syphilis: epidemiological and ethnographic analysis and implications for control. | 2002 | Sex Transm Infect | pmid:12083438 |
| Reshetniak VI et al. | [Eradication of Helicobacter pylori in patients with duodenal ulcer following the short course of treatment with azitromycin and amoxycillin]. | 2002 | Antibiot. Khimioter. | pmid:12087718 |
| Kays MB et al. | Azithromycin treatment failure in community-acquired pneumonia caused by Streptococcus pneumoniae resistant to macrolides by a 23S rRNA mutation. | 2002 | Diagn. Microbiol. Infect. Dis. | pmid:12088625 |
| Breier AR et al. | Microbiological assay for azithromycin in pharmaceutical formulations. | 2002 | J Pharm Biomed Anal | pmid:12093530 |
| Bosch-Driessen LH et al. | A prospective, randomized trial of pyrimethamine and azithromycin vs pyrimethamine and sulfadiazine for the treatment of ocular toxoplasmosis. | 2002 | Am. J. Ophthalmol. | pmid:12095805 |
| Butler T | Reduction of MIC of azithromycin for Salmonella typhi and Staphylococcus aureus in broth exposed to previous growth of Salmonella typhi. | 2002 | J. Antimicrob. Chemother. | pmid:12096025 |
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| Williams ES and Miller JM | Results from late-breaking clinical trial sessions at the American College of Cardiology 51st Annual Scientific Session. | 2002 | J. Am. Coll. Cardiol. | pmid:12113263 |
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| Infection fighters. MAC prevention takes a holiday. | 2000 | TreatmentUpdate | pmid:12132450 | |
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| Fry AM et al. | Adverse and beneficial secondary effects of mass treatment with azithromycin to eliminate blindness due to trachoma in Nepal. | 2002 | Clin. Infect. Dis. | pmid:12145722 |
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| Yee CL et al. | Tendon or joint disorders in children after treatment with fluoroquinolones or azithromycin. | 2002 | Pediatr. Infect. Dis. J. | pmid:12182376 |
| Clark C et al. | In vitro selection of resistance in Haemophilus influenzae by amoxicillin-clavulanate, cefpodoxime, cefprozil, azithromycin, and clarithromycin. | 2002 | Antimicrob. Agents Chemother. | pmid:12183253 |
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| Lau CY and Qureshi AK | Azithromycin versus doxycycline for genital chlamydial infections: a meta-analysis of randomized clinical trials. | 2002 | Sex Transm Dis | pmid:12218839 |
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| Frank E et al. | A multicenter, open-label, randomized comparison of levofloxacin and azithromycin plus ceftriaxone in hospitalized adults with moderate to severe community-acquired pneumonia. | 2002 | Clin Ther | pmid:12240780 |
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| Augenbraun MH | Treatment of syphilis 2001: nonpregnant adults. | 2002 | Clin. Infect. Dis. | pmid:12353205 |
| Steinberg JM and Srugo I | Reoccurrence of culture-positive pertussis in an infant initially treated with azithromycin and steroids. | 2002 | Arch Pediatr Adolesc Med | pmid:12361458 |
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| Hammerschlag MR | Effect of azithromycin on endothelial function of patients with coronary artery disease and evidence of Chlamydia pneumoniae infection. | 2002 | Circulation | pmid:12370232 |