Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Airway Obstruction D000402 13 associated lipids
Stomach Ulcer D013276 75 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Otitis Media D010033 12 associated lipids
Carcinoma, Basal Cell D002280 6 associated lipids
Bacterial Infections D001424 21 associated lipids
Pain D010146 64 associated lipids
Stomach Diseases D013272 7 associated lipids
Genital Diseases, Female D005831 7 associated lipids
Lung Diseases D008171 37 associated lipids
Sarcoidosis D012507 13 associated lipids
Hyperglycemia D006943 21 associated lipids
Carcinoma, Squamous Cell D002294 14 associated lipids
Skin Neoplasms D012878 12 associated lipids
Burns D002056 34 associated lipids
Inflammation D007249 119 associated lipids
Colitis D003092 69 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Spangler SK et al. Effect of CO2 on susceptibilities of anaerobes to erythromycin, azithromycin, clarithromycin, and roxithromycin. 1994 Antimicrob. Agents Chemother. pmid:8192445
Stamler DA et al. Azithromycin pharmacokinetics and intracellular concentrations in Legionella pneumophila-infected and uninfected guinea pigs and their alveolar macrophages. 1994 Antimicrob. Agents Chemother. pmid:8192446
Wang JH et al. Azithromycin in the treatment of pneumonia caused by Chlamydia pneumoniae: report of a case. 1994 J. Formos. Med. Assoc. pmid:7866068
[Newly approved specialty drugs in Austria and new knowledge about currently available specialty drugs. Zithromax capsules, dried syrup]. 1994 Wien. Klin. Wochenschr. pmid:7975673
Cynamon MH et al. Comparative activities of azithromycin and clarithromycin against Mycobacterium avium infection in beige mice. 1994 Antimicrob. Agents Chemother. pmid:7979270
Klemens SP and Cynamon MH Activities of azithromycin and clarithromycin against nontuberculous mycobacteria in beige mice. 1994 Antimicrob. Agents Chemother. pmid:7979271
Schönwald S et al. Three-day azithromycin compared with ten-day roxithromycin treatment of atypical pneumonia. 1994 Scand. J. Infect. Dis. pmid:7747094
Steingrímsson O et al. Single dose azithromycin treatment of gonorrhea and infections caused by C. trachomatis and U. urealyticum in men. 1994 Jan-Feb Sex Transm Dis pmid:8140488
Tyndall MW et al. Single dose azithromycin for the treatment of chancroid: a randomized comparison with erythromycin. 1994 Jul-Aug Sex Transm Dis pmid:7974076
Lang R et al. Therapeutic effects of roxithromycin and azithromycin in experimental murine brucellosis. 1994 Jul-Aug Chemotherapy pmid:8082413
Handsfield HH et al. Multicenter trial of single-dose azithromycin vs. ceftriaxone in the treatment of uncomplicated gonorrhea. Azithromycin Gonorrhea Study Group. 1994 Mar-Apr Sex Transm Dis pmid:9071422
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Ives DV et al. Impact of clarithromycin and azithromycin on patterns of treatment and survival among AIDS patients with disseminated Mycobacterium avium complex. 1995 AIDS pmid:7755914
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Adal KA et al. Photo quiz. Bacillary angiomatosis. 1995 Clin. Infect. Dis. pmid:7727641
Bermudez LE et al. Efficacy of azithromycin and rifabutin in preventing infection by Mycobacterium avium complex in beige mice. 1995 J. Antimicrob. Chemother. pmid:8591938
Domingo S et al. Comparative activity of azithromycin and doxycycline against Brucella spp. infection in mice. 1995 J. Antimicrob. Chemother. pmid:8591939
Nash KA and Inderlied CB Genetic basis of macrolide resistance in Mycobacterium avium isolated from patients with disseminated disease. 1995 Antimicrob. Agents Chemother. pmid:8592991
Bohte R et al. Levels of azithromycin and alpha-1 acid glycoprotein in serum in patients with community-acquired pneumonia. 1995 Antimicrob. Agents Chemother. pmid:8593024
Tribble D et al. Efficacy of azithromycin for typhoid fever. 1995 Clin. Infect. Dis. pmid:8645805
Silvestri M et al. Azithromycin induces in vitro a time-dependent increase in the intracellular killing of Staphylococcus aureus by human polymorphonuclear leucocytes without damaging phagocytes. 1995 J. Antimicrob. Chemother. pmid:8821593
Patton DL et al. The activity of azithromycin on the infectivity of Chlamydia trachomatis in human amniotic cells. 1995 J. Antimicrob. Chemother. pmid:8821594
Lo KK et al. An open non-comparative pilot study with azithromycin in the treatment of non-gonococcal urethritis in the sexually transmitted disease clinics in Hong Kong. 1995 Ann. Acad. Med. Singap. pmid:8849186
Martin DH et al. Comparison of azithromycin and ceftriaxone for the treatment of chancroid. 1995 Clin. Infect. Dis. pmid:8562752
Clancy J et al. Assays to detect and characterize synthetic agents that inhibit the ErmC methyltransferase. 1995 J. Antibiot. pmid:8557568
Amsden GW Macrolides versus azalides: a drug interaction update. 1995 Ann Pharmacother pmid:8547740
Kuschner RA et al. Use of azithromycin for the treatment of Campylobacter enteritis in travelers to Thailand, an area where ciprofloxacin resistance is prevalent. 1995 Clin. Infect. Dis. pmid:8527539
Wahlstrom E et al. Improvement in cyclosporine-associated gingival hyperplasia with azithromycin therapy. 1995 N. Engl. J. Med. pmid:7854392
Beckers CJ et al. Inhibition of cytoplasmic and organellar protein synthesis in Toxoplasma gondii. Implications for the target of macrolide antibiotics. 1995 J. Clin. Invest. pmid:7814637
Friis HM [Azithromycin--an exciting new antibiotic]. 1995 Ugeskr. Laeg. pmid:7831724
Dessau RB [Azithromycin]. 1995 Ugeskr. Laeg. pmid:7831733
Péc J et al. [Treatment of chlamydia infections and a brief review of the problems]. 1995 Bratisl Lek Listy pmid:7633932
Bowden FJ et al. Azithromycin and syphilis. 1995 Genitourin Med pmid:7635501
Yeo AE and Rieckmann KH Increased antimalarial activity of azithromycin during prolonged exposure of Plasmodium falciparum in vitro. 1995 Int. J. Parasitol. pmid:7635629
Bamberger DM et al. Azithromycin in an experimental Staphylococcus aureus abscess model. 1995 J. Antimicrob. Chemother. pmid:7592175
Adegbola RA et al. Effect of azithromycin on pharyngeal microflora. 1995 Pediatr. Infect. Dis. J. pmid:7603826
Vartiovaara I Living with Lyme. 1995 Lancet pmid:7605437
Fouda HG and Schneider RP Quantitative determination of the antibiotic azithromycin in human serum by high-performance liquid chromatography (HPLC)-atmospheric pressure chemical ionization mass spectrometry: correlation with a standard HPLC-electrochemical method. 1995 Ther Drug Monit pmid:7624907
Goldstein EJ et al. Comparative in vitro activities of azithromycin, Bay y 3118, levofloxacin, sparfloxacin, and 11 other oral antimicrobial agents against 194 aerobic and anaerobic bite wound isolates. 1995 Antimicrob. Agents Chemother. pmid:7625795
Barry AL et al. Relative potencies of azithromycin, clarithromycin and five other orally administered antibiotics. 1995 J. Antimicrob. Chemother. pmid:7628991
Stamm WE et al. Azithromycin for empirical treatment of the nongonococcal urethritis syndrome in men. A randomized double-blind study. 1995 JAMA pmid:7629982
Schmid GP and Fontanarosa PB Evolving strategies for management of the nongonococcal urethritis syndrome. 1995 JAMA pmid:7629989
Sadiq ST et al. Effects of azithromycin on malariometric indices in The Gambia. 1995 Lancet pmid:7564674
Pascual A et al. Factors affecting the intracellular accumulation and activity of azithromycin. 1995 J. Antimicrob. Chemother. pmid:7768786
Beghi G et al. Efficacy and tolerability of azithromycin versus amoxicillin/clavulanic acid in acute purulent exacerbation of chronic bronchitis. 1995 J Chemother pmid:7666122
Amland PF et al. A prospective, double-blind, placebo-controlled trial of a single dose of azithromycin on postoperative wound infections in plastic surgery. 1995 Plast. Reconstr. Surg. pmid:7480237
[New ways of antibiotic therapy]. 1995 Internist (Berl) pmid:9431354
Bessette RE and Amsden GW Treatment of non-HIV cryptosporidial diarrhea with azithromycin. 1995 Ann Pharmacother pmid:8845560