Azithramycine

Azithramycine is a lipid of Polyketides (PK) class. Azithramycine is associated with abnormalities such as Respiratory Tract Infections, Pneumonia, Lower respiratory tract infection, Infection and Nonspecific urethritis. The involved functions are known as Lysis, Selection, Genetic, Mutation, Relapse and Adaptation. Azithramycine often locates in Blood, Respiratory System, Genitourinary system, Back and Chest. The associated genes with Azithramycine are Genes, rRNA, Genome, RPL22 gene, OPRM1 gene and tryptic soy broth. The related lipids are Liposomes, Phosphatidylserines, Promega, Lipopolysaccharides and Steroids. The related experimental models are Mouse Model, Knock-out and Tissue Model.

Cross Reference

Introduction

To understand associated biological information of Azithramycine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Azithramycine?

Azithramycine is suspected in Infection, Pneumonia, Trachoma, Respiratory Tract Infections, Gonorrhea, Infectious disease of lung and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Azithramycine

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Airway Obstruction D000402 13 associated lipids
Stomach Ulcer D013276 75 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Otitis Media D010033 12 associated lipids
Carcinoma, Basal Cell D002280 6 associated lipids
Bacterial Infections D001424 21 associated lipids
Pain D010146 64 associated lipids
Stomach Diseases D013272 7 associated lipids
Genital Diseases, Female D005831 7 associated lipids
Lung Diseases D008171 37 associated lipids
Sarcoidosis D012507 13 associated lipids
Hyperglycemia D006943 21 associated lipids
Carcinoma, Squamous Cell D002294 14 associated lipids
Skin Neoplasms D012878 12 associated lipids
Burns D002056 34 associated lipids
Inflammation D007249 119 associated lipids
Colitis D003092 69 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Azithramycine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Azithramycine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Azithramycine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Azithramycine?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Azithramycine?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Azithramycine?

Mouse Model

Mouse Model are used in the study 'Azithromycin increases in vitro fibronectin production through interactions between macrophages and fibroblasts stimulated with Pseudomonas aeruginosa.' (Cory TJ et al., 2013), Mouse Model are used in the study 'Efficacy of azithromycin, clarithromycin and beta-lactam agents against experimentally induced bronchopneumonia caused by Haemophilus influenzae in mice.' (Miyazaki S et al., 2001), Mouse Model are used in the study 'Oral anti-pneumococcal activity and pharmacokinetic profiling of a novel peptide deformylase inhibitor.' (Gross M et al., 2004), Mouse Model are used in the study 'Inhibition of quorum sensing in Pseudomonas aeruginosa by azithromycin and its effectiveness in urinary tract infections.' (Bala A et al., 2011) and Mouse Model are used in the study 'Enhanced efficacy of single-dose versus multi-dose azithromycin regimens in preclinical infection models.' (Girard D et al., 2005).

Knock-out

Knock-out are used in the study 'Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.' (Bulman ZP et al., 2017) and Knock-out are used in the study 'Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.' (Mulet X et al., 2009).

Tissue Model

Tissue Model are used in the study 'Development of a population pharmacokinetic model characterizing the tissue distribution of azithromycin in healthy subjects.' (Zheng S et al., 2014).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Azithramycine

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Per page 10 20 50 100 | Total 4404
Authors Title Published Journal PubMed Link
Slavinsky J et al. Factors associated with the decline in sexually transmitted infections among HIV-positive women. 2000 J. Acquir. Immune Defic. Syndr. pmid:10708065
Angelilli ML et al. Palatability of oral antibiotics among children in an urban primary care center. 2000 Arch Pediatr Adolesc Med pmid:10710025
Rino BE et al. Azithromycin in the treatment of plasmodium falciparum gametocytes: a preliminary observation. 2000 J. Trop. Pediatr. pmid:10730047
Canut Blasco A et al. [A randomized, prospective and comparative study is a clinical trial]. 2000 Med Clin (Barc) pmid:10734631
Potts JM et al. Association of chronic urinary symptoms in women and Ureaplasma urealyticum. 2000 Urology pmid:10736488
Ouchi K Chlamydia pneumoniae and atherosclerosis. 1999 Jpn. J. Infect. Dis. pmid:10738358
Schissel DJ et al. Azithromycin eruption in infectious mononucleosis: a proposed mechanism of interaction. 2000 Cutis pmid:10738636
Giacometti A et al. Activity of nitazoxanide alone and in combination with azithromycin and rifabutin against Cryptosporidium parvum in cell culture. 2000 J. Antimicrob. Chemother. pmid:10747821
Nishi Y et al. [Effect of macrolide antibiotics on adhesion by cancer cells]. 2000 Jpn J Antibiot pmid:10756450
Wenisch C [Pharmacokinetic effects of antibiotics on the development of bacterial resistance particularly in reference to azithromycin]. 2000 Wien Med Wochenschr pmid:10756595
Diculencu D et al. [The postantibiotic effect of azithromycin on respiratory pathogens]. 1998 Jul-Dec Rev Med Chir Soc Med Nat Iasi pmid:10756861
Somani J et al. Multiple drug-resistant Chlamydia trachomatis associated with clinical treatment failure. 2000 J. Infect. Dis. pmid:10762573
El-Sadr WM et al. Discontinuation of prophylaxis for Mycobacterium avium complex disease in HIV-infected patients who have a response to antiretroviral therapy. Terry Beirn Community Programs for Clinical Research on AIDS. 2000 N. Engl. J. Med. pmid:10766581
Brieland JK et al. Efficacy of SCH27899 in an animal model of Legionnaires' disease using immunocompromised A/J mice. 2000 Antimicrob. Agents Chemother. pmid:10770771
Najib MM et al. Cost-effectiveness of sparfloxacin compared with other oral antimicrobials in outpatient treatment of community-acquired pneumonia. 2000 Pharmacotherapy pmid:10772376
Laming AC et al. A targeted, single-dose azithromycin strategy for trachoma. 2000 Med. J. Aust. pmid:10772587
Donders GG Treatment of sexually transmitted bacterial diseases in pregnant women. 2000 Drugs pmid:10776830
Bujanda L et al. Ranitidine bismuth citrate plus azithromycin for Helicobacter pylori eradication. 2000 J. Clin. Gastroenterol. pmid:10777206
Ress BD and Gross EM Irreversible sensorineural hearing loss as a result of azithromycin ototoxicity. A case report. 2000 Ann. Otol. Rhinol. Laryngol. pmid:10778901
Miller SA et al. Chlamydia pneumoniae activates nuclear factor kappaB and activator protein 1 in human vascular smooth muscle and induces cellular proliferation. 2000 J. Surg. Res. pmid:10781378